메뉴 건너뛰기




Volumn 83, Issue 13, 2009, Pages 6578-6590

Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CLATHRIN; LYSINE; NEF PROTEIN; TRANSCRIPTION FACTOR AP 2; NEF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 67449092266     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00548-09     Document Type: Article
Times cited : (56)

References (79)
  • 1
    • 0023036903 scopus 로고
    • Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen
    • Acres, R. B., P. J. Conlon, D. Y. Mochizuki, and B. Gallis. 1986. Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen. J. Biol. Chem. 261:16210-16214.
    • (1986) J. Biol. Chem. , vol.261 , pp. 16210-16214
    • Acres, R.B.1    Conlon, P.J.2    Mochizuki, D.Y.3    Gallis, B.4
  • 2
    • 0028180868 scopus 로고
    • Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
    • DOI 10.1016/0092-8674(94)90360-3
    • Aiken, C., J. Konner, N. R. Landau, M. E. Lenburg, and D. Trono. 1994. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76:853-864. (Pubitemid 2046514)
    • (1994) Cell , vol.76 , Issue.5 , pp. 853-864
    • Aiken, C.1    Konner, J.2    Landau, N.R.3    Lenburg, M.E.4    Trono, D.5
  • 3
    • 0029924038 scopus 로고    scopus 로고
    • Mutational analysis of HIV-1 Nef: Identification of two mutants that are temperature-sensitive for CD4 downregulation
    • DOI 10.1006/viro.1996.0116
    • Aiken, C., L. Krause, Y. L. Chen, and D. Trono. 1996. Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation. Virology 217:293-300. (Pubitemid 26103618)
    • (1996) Virology , vol.217 , Issue.1 , pp. 293-300
    • Aiken, C.1    Krause, L.2    Chen, Y.-L.3    Trono, D.4
  • 4
    • 0028216346 scopus 로고
    • The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef
    • Anderson, S. J., M. Lenburg, N. R. Landau, and J. V. Garcia. 1994. The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef. J. Virol. 68:3092-3101. (Pubitemid 24129758)
    • (1994) Journal of Virology , vol.68 , Issue.5 , pp. 3092-3101
    • Anderson, S.J.1    Lenburg, M.2    Landau, N.R.3    Victor Garcia, J.4
  • 5
    • 44649173294 scopus 로고    scopus 로고
    • HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: Analysis using short interfering RNA and knock-out mice
    • Atkins, K. M., L. Thomas, R. T. Youker, M. J. Harriff, F. Pissani, H. You, and G. Thomas. 2008. HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice. J. Biol. Chem. 283:11772-11784.
    • (2008) J. Biol. Chem. , vol.283 , pp. 11772-11784
    • Atkins, K.M.1    Thomas, L.2    Youker, R.T.3    Harriff, M.J.4    Pissani, F.5    You, H.6    Thomas, G.7
  • 6
    • 0032101334 scopus 로고    scopus 로고
    • The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function
    • DOI 10.1093/emboj/17.11.2982
    • Babst, M., B. Wendland, E. J. Estepa, and S. D. Emr. 1998. The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J. 17:2982-2993. (Pubitemid 28254371)
    • (1998) EMBO Journal , vol.17 , Issue.11 , pp. 2982-2993
    • Babst, M.1    Wendland, B.2    Estepa, E.J.3    Emr, S.D.4
  • 7
    • 0028062729 scopus 로고
    • Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic
    • Benichou, S., M. Bomsel, M. Bodeus, H. Durand, M. Doute, F. Letourneur, J. Camonis, and R. Benarous. 1994. Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic. J. Biol. Chem. 269:30073-30076.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30073-30076
    • Benichou, S.1    Bomsel, M.2    Bodeus, M.3    Durand, H.4    Doute, M.5    Letourneur, F.6    Camonis, J.7    Benarous, R.8
  • 8
    • 0027158904 scopus 로고
    • Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
    • Benson, R. E., A. Sanfridson, J. S. Ottinger, C. Doyle, and B. R. Cullen. 1993. Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection. J. Exp. Med. 177:1561-1566.
    • (1993) J. Exp. Med. , vol.177 , pp. 1561-1566
    • Benson, R.E.1    Sanfridson, A.2    Ottinger, J.S.3    Doyle, C.4    Cullen, B.R.5
  • 9
    • 37749032764 scopus 로고    scopus 로고
    • Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum
    • Binette, J., M. Dube, J. Mercier, D. Halawani, M. Latterich, and E. A. Cohen. 2007. Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum. Retrovirology 4:75.
    • (2007) Retrovirology , vol.4 , pp. 75
    • Binette, J.1    Dube, M.2    Mercier, J.3    Halawani, D.4    Latterich, M.5    Cohen, E.A.6
  • 10
    • 0033959713 scopus 로고    scopus 로고
    • ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking
    • Bishop, N., and P. Woodman. 2000. ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking. Mol. Biol. Cell 11:227-239.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 227-239
    • Bishop, N.1    Woodman, P.2
  • 11
    • 0037074008 scopus 로고    scopus 로고
    • HIV-1 Nef downregulates MHC-I by a PACS-1- And PI3K-regulated ARF6 endocytic pathway
    • DOI 10.1016/S0092-8674(02)01162-5
    • Blagoveshchenskaya, A. D., L. Thomas, S. F. Feliciangeli, C. H. Hung, and G. Thomas. 2002. HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway. Cell 111:853-866. (Pubitemid 36106406)
    • (2002) Cell , vol.111 , Issue.6 , pp. 853-866
    • Blagoveshchenskaya, A.D.1    Thomas, L.2    Feliciangeli, S.F.3    Hung, C.-H.4    Thomas, G.5
  • 12
    • 0003362844 scopus 로고    scopus 로고
    • Protein labeling and immunoprecipitation
    • J. S. Bonifacino, M. Dasso, J. B. Harford, J. Lippincott-Schwartz, and K. Yamada (ed.), John Wiley & Sons, New York, NY
    • Bonifacino, J. S. 1998. Protein labeling and immunoprecipitation. In J. S. Bonifacino, M. Dasso, J. B. Harford, J. Lippincott-Schwartz, and K. Yamada (ed.), Current protocols in cell biology. John Wiley & Sons, New York, NY.
    • (1998) Current Protocols in Cell Biology
    • Bonifacino, J.S.1
  • 14
    • 0032488027 scopus 로고    scopus 로고
    • A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
    • Bresnahan, P. A., W. Yonemoto, S. Ferrell, D. Williams-Herman, R. Geleziunas, and W. C. Greene. 1998. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr. Biol. 8:1235-1238.
    • (1998) Curr. Biol. , vol.8 , pp. 1235-1238
    • Bresnahan, P.A.1    Yonemoto, W.2    Ferrell, S.3    Williams-Herman, D.4    Geleziunas, R.5    Greene, W.C.6
  • 15
    • 33845513921 scopus 로고    scopus 로고
    • Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane
    • DOI 10.1111/j.1600-0854.2006.00512.x
    • Burtey, A., J. Z. Rappoport, J. Bouchet, S. Basmaciogullari, J. Guatelli, S. M. Simon, S. Benichou, and A. Benmerah. 2007. Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane. Traffic 8:61-76. (Pubitemid 44921883)
    • (2007) Traffic , vol.8 , Issue.1 , pp. 61-76
    • Burtey, A.1    Rappoport, J.Z.2    Bouchet, J.3    Basmaciogullari, S.4    Guatelli, J.5    Simon, S.M.6    Benichou, S.7    Benmerah, A.8
  • 16
    • 21744433861 scopus 로고    scopus 로고
    • Biochemistry: Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase
    • DOI 10.1126/science.1110340
    • Cadwell, K., and L. Coscoy. 2005. Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase. Science 309:127-130. (Pubitemid 40934990)
    • (2005) Science , vol.309 , Issue.5731 , pp. 127-130
    • Cadwell, K.1    Coscoy, L.2
  • 17
    • 34247129671 scopus 로고    scopus 로고
    • Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor
    • DOI 10.1128/JVI.02725-06
    • Chaudhuri, R., O. W. Lindwasser, W. J. Smith, J. H. Hurley, and J. S. Bonifacino. 2007. Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. J. Virol. 81:3877-3890. (Pubitemid 46586884)
    • (2007) Journal of Virology , vol.81 , Issue.8 , pp. 3877-3890
    • Chaudhuri, R.1    Lindwasser, O.W.2    Smith, W.J.3    Hurley, J.H.4    Bonifacino, J.S.5
  • 18
    • 62749181801 scopus 로고    scopus 로고
    • A basic patch on α-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex
    • Chaudhuri, R., R. Mattera, O. W. Lindwasser, M. S. Robinson, and J. S. Bonifacino. 2009. A basic patch on α-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. J. Virol. 83:2518-2530.
    • (2009) J. Virol. , vol.83 , pp. 2518-2530
    • Chaudhuri, R.1    Mattera, R.2    Lindwasser, O.W.3    Robinson, M.S.4    Bonifacino, J.S.5
  • 19
    • 0028302998 scopus 로고
    • Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene
    • Chowers, M. Y., C. A. Spina, T. J. Kwoh, N. J. Fitch, D. D. Richman, and J. C. Guatelli. 1994. Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. J. Virol. 68:2906-2914. (Pubitemid 24129738)
    • (1994) Journal of Virology , vol.68 , Issue.5 , pp. 2906-2914
    • Chowers, M.Y.1    Spina, C.A.2    Kwoh, T.J.3    Fitch, N.J.S.4    Richman, D.D.5    Guatelli, J.C.6
  • 20
    • 13444291133 scopus 로고    scopus 로고
    • Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes
    • DOI 10.1128/JVI.79.4.2066-2078.2005
    • Coleman, S. H., N. Van Damme, J. R. Day, C. M. Noviello, D. Hitchin, R. Madrid, S. Benichou, and J. C. Guatelli. 2005. Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes. J. Virol. 79:2066-2078. (Pubitemid 40204564)
    • (2005) Journal of Virology , vol.79 , Issue.4 , pp. 2066-2078
    • Coleman, S.H.1    Van Damme, N.2    Day, J.R.3    Noviello, C.M.4    Hitchin, D.5    Madrid, R.6    Benichou, S.7    Guatelli, J.C.8
  • 21
  • 22
    • 0032530773 scopus 로고    scopus 로고
    • Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
    • Craig, H. M., M. W. Pandori, and J. C. Guatelli. 1998. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. Proc. Natl. Acad. Sci. USA 95:11229-11234.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11229-11234
    • Craig, H.M.1    Pandori, M.W.2    Guatelli, J.C.3
  • 24
    • 0026717493 scopus 로고
    • Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes
    • de Ronde, A., B. Klaver, W. Keulen, L. Smit, and J. Goudsmit. 1992. Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes. Virology 188:391-395.
    • (1992) Virology , vol.188 , pp. 391-395
    • De Ronde, A.1    Klaver, B.2    Keulen, W.3    Smit, L.4    Goudsmit, J.5
  • 25
    • 34248198351 scopus 로고    scopus 로고
    • The γ/σ1 and α/σ2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site
    • Doray, B., I. Lee, J. Knisely, G. Bu, and S. Kornfeld. 2007. The γ/σ1 and α/σ2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site. Mol. Biol. Cell 18:1887-1896.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1887-1896
    • Doray, B.1    Lee, I.2    Knisely, J.3    Bu, G.4    Kornfeld, S.5
  • 26
  • 27
    • 53549119688 scopus 로고    scopus 로고
    • HIV-1 Nef: At the crossroads
    • Foster, J. L., and J. V. Garcia. 2008. HIV-1 Nef: at the crossroads. Retrovirology 5:84.
    • (2008) Retrovirology , vol.5 , pp. 84
    • Foster, J.L.1    Garcia, J.V.2
  • 28
    • 0025733252 scopus 로고
    • Serine phosphorylationindependent downregulation of cell-surface CD4 by nef
    • Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350:508-511. (Pubitemid 21912265)
    • (1991) Nature , vol.350 , Issue.6318 , pp. 508-511
    • Garcia, J.V.1    Miller, A.D.2
  • 29
    • 0034894379 scopus 로고    scopus 로고
    • Structure-function relationships in HIV-1 Nef
    • DOI 10.1093/embo-reports/kve141
    • Geyer, M., O. T. Fackler, and B. M. Peterlin. 2001. Structure-function relationships in HIV-1 Nef. EMBO Rep. 2:580-585. (Pubitemid 32707703)
    • (2001) EMBO Reports , vol.2 , Issue.7 , pp. 580-585
    • Geyer, M.1    Fackler, O.T.2    Peterlin, B.M.3
  • 31
    • 0030587831 scopus 로고    scopus 로고
    • Molecular Analysis of the Cytoplasmic Domain of CD4: Overlapping but Noncompetitive Requirement for lck Association and Down-Regulation by Nef
    • Gratton, S., X. J. Yao, S. Venkatesan, E. A. Cohen, and R. P. Sekaly. 1996. Molecular analysis of the cytoplasmic domain of CD4: overlapping but noncompetitive requirement for lck association and down-regulation by Nef. J. Immunol. 157:3305-3311. (Pubitemid 126449140)
    • (1996) Journal of Immunology , vol.157 , Issue.8 , pp. 3305-3311
    • Gratton, S.1    Yao, X.-J.2    Venkatesan, S.3    Cohen, E.A.4    Sekaly, R.-P.5
  • 32
    • 0032488055 scopus 로고    scopus 로고
    • A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
    • Greenberg, M., L. DeTulleo, I. Rapoport, J. Skowronski, and T. Kirchhausen. 1998. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Curr. Biol. 8:1239-1242.
    • (1998) Curr. Biol. , vol.8 , pp. 1239-1242
    • Greenberg, M.1    Detulleo, L.2    Rapoport, I.3    Skowronski, J.4    Kirchhausen, T.5
  • 33
    • 0030684068 scopus 로고    scopus 로고
    • Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
    • Greenberg, M. E., S. Bronson, M. Lock, M. Neumann, G. N. Pavlakis, and J. Skowronski. 1997. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16:6964-6976. (Pubitemid 27520797)
    • (1997) EMBO Journal , vol.16 , Issue.23 , pp. 6964-6976
    • Greenberg, M.E.1    Bronson, S.2    Lock, M.3    Neumann, M.4    Pavlakis, G.N.5    Skowronski, J.6
  • 34
    • 0029795040 scopus 로고    scopus 로고
    • The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR
    • Grzesiek, S., S. J. Stahl, P. T. Wingfield, and A. Bax. 1996. The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR. Biochemistry 35:10256-10261.
    • (1996) Biochemistry , vol.35 , pp. 10256-10261
    • Grzesiek, S.1    Stahl, S.J.2    Wingfield, P.T.3    Bax, A.4
  • 36
    • 2542448950 scopus 로고    scopus 로고
    • Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomes
    • Hislop, J. N., A. Marley, and M. Von Zastrow. 2004. Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomes. J. Biol. Chem. 279:22522-22531.
    • (2004) J. Biol. Chem. , vol.279 , pp. 22522-22531
    • Hislop, J.N.1    Marley, A.2    Von Zastrow, M.3
  • 37
    • 0030958508 scopus 로고    scopus 로고
    • Identification of regions in HIV-1 Nef required for efficient downregulation of cell surface CD4
    • DOI 10.1006/viro.1997.8517
    • Hua, J., W. Blair, R. Truant, and B. R. Cullen. 1997. Identification of regions in HIV-1 Nef required for efficient downregulation of cell surface CD4. Virology 231:231-238. (Pubitemid 27244189)
    • (1997) Virology , vol.231 , Issue.2 , pp. 231-238
    • Hua, J.1    Blair, W.2    Truant, R.3    Cullen, B.R.4
  • 38
    • 34347377736 scopus 로고    scopus 로고
    • The transmembrane domain of acid trehalase mediates ubiquitin-independent multivesicular body pathway sorting
    • Huang, J., F. Reggiori, and D. J. Klionsky. 2007. The transmembrane domain of acid trehalase mediates ubiquitin-independent multivesicular body pathway sorting. Mol. Biol. Cell 18:2511-2524.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 2511-2524
    • Huang, J.1    Reggiori, F.2    Klionsky, D.J.3
  • 40
    • 39149132089 scopus 로고    scopus 로고
    • ESCRT complexes and the biogenesis of multivesicular bodies
    • Hurley, J. H. 2008. ESCRT complexes and the biogenesis of multivesicular bodies. Curr. Opin. Cell Biol. 20:4-11.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 4-11
    • Hurley, J.H.1
  • 42
    • 0035080263 scopus 로고    scopus 로고
    • Nef-induced CD4 downregulation: A diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to β-COP
    • DOI 10.1128/JVI.75.8.3971-3976.2001
    • Janvier, K., H. Craig, S. Le Gall, R. Benarous, J. Guatelli, O. Schwartz, and S. Benichou. 2001. Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to β-COP. J. Virol. 75:3971-3976. (Pubitemid 32246406)
    • (2001) Journal of Virology , vol.75 , Issue.8 , pp. 3971-3976
    • Janvier, K.1    Craig, H.2    Le Gall, S.3    Benarous, R.4    Guatelli, J.5    Schwartz, O.6    Benichou, S.7
  • 43
    • 0346102461 scopus 로고    scopus 로고
    • Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ-σ1 and AP-3 δ-σ3 hemicomplexes
    • DOI 10.1083/jcb.200307157
    • Janvier, K., Y. Kato, M. Boehm, J. R. Rose, J. A. Martina, B. Y. Kim, S. Venkatesan, and J. S. Bonifacino. 2003. Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ-σ1 and AP-3 δ-σ3 hemicomplexes. J. Cell Biol. 163:1281-1290. (Pubitemid 38032089)
    • (2003) Journal of Cell Biology , vol.163 , Issue.6 , pp. 1281-1290
    • Janvier, K.1    Kato, Y.2    Boehm, M.3    Rose, J.R.4    Martina, J.A.5    Kim, B.-Y.6    Venkatesan, S.7    Bonifacino, J.S.8
  • 44
    • 50949130687 scopus 로고    scopus 로고
    • Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation
    • Jin, Y. J., C. Y. Cai, X. Zhang, and S. J. Burakoff. 2008. Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation. J. Immunol. 180:7878-7886.
    • (2008) J. Immunol. , vol.180 , pp. 7878-7886
    • Jin, Y.J.1    Cai, C.Y.2    Zhang, X.3    Burakoff, S.J.4
  • 45
    • 23844509821 scopus 로고    scopus 로고
    • HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent
    • Jin, Y. J., C. Y. Cai, X. Zhang, H. T. Zhang, J. A. Hirst, and S. J. Burakoff. 2005. HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent. J. Immunol. 175:3157-3164. (Pubitemid 41170537)
    • (2005) Journal of Immunology , vol.175 , Issue.5 , pp. 3157-3164
    • Jin, Y.-J.1    Cai, C.Y.2    Zhang, X.3    Zhang, H.-T.4    Hirst, J.A.5    Burakoff, S.J.6
  • 46
    • 0036902646 scopus 로고    scopus 로고
    • Receptor downregulation and multivesicular-body sorting
    • Katzmann, D. J., G. Odorizzi, and S. D. Emr. 2002. Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell Biol. 3:893-905.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 893-905
    • Katzmann, D.J.1    Odorizzi, G.2    Emr, S.D.3
  • 48
    • 0028835788 scopus 로고
    • Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
    • Kirchhoff, F., T. C. Greenough, D. B. Brettler, J. L. Sullivan, and R. C. Desrosiers. 1995. Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N. Engl. J. Med. 332:228-232.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 228-232
    • Kirchhoff, F.1    Greenough, T.C.2    Brettler, D.B.3    Sullivan, J.L.4    Desrosiers, R.C.5
  • 49
    • 0033578072 scopus 로고    scopus 로고
    • Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- And Vpu-inhibitable manner
    • Lama, J., A. Mangasarian, and D. Trono. 1999. Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Curr. Biol. 9:622-631.
    • (1999) Curr. Biol. , vol.9 , pp. 622-631
    • Lama, J.1    Mangasarian, A.2    Trono, D.3
  • 50
    • 33947627531 scopus 로고    scopus 로고
    • Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses
    • Lindwasser, O. W., R. Chaudhuri, and J. S. Bonifacino. 2007. Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses. Curr. Mol. Med. 7:171-184.
    • (2007) Curr. Mol. Med. , vol.7 , pp. 171-184
    • Lindwasser, O.W.1    Chaudhuri, R.2    Bonifacino, J.S.3
  • 51
    • 38349109364 scopus 로고    scopus 로고
    • A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2
    • Lindwasser, O. W., W. J. Smith, R. Chaudhuri, P. Yang, J. H. Hurley, and J. S. Bonifacino. 2008. A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2. J. Virol. 82:1166-1174.
    • (2008) J. Virol. , vol.82 , pp. 1166-1174
    • Lindwasser, O.W.1    Smith, W.J.2    Chaudhuri, R.3    Yang, P.4    Hurley, J.H.5    Bonifacino, J.S.6
  • 52
    • 0028076866 scopus 로고
    • Cell surface CD4 downregulation and resistance to superinfection induced by a defective provirus of HIV-1
    • DOI 10.1006/viro.1994.1683
    • Little, S. J., N. L. Riggs, M. Y. Chowers, N. J. Fitch, D. D. Richman, C. A. Spina, and J. C. Guatelli. 1994. Cell surface CD4 downregulation and re- sistance to superinfection induced by a defective provirus of HIV-1. Virology 205:578-582. (Pubitemid 24371704)
    • (1994) Virology , vol.205 , Issue.2 , pp. 578-582
    • Little, S.J.1    Riggs, N.L.2    Chowers, M.Y.3    Fitch, N.J.S.4    Richman, D.D.5    Spina, C.A.6    Guatelli, J.C.7
  • 53
    • 34548510349 scopus 로고    scopus 로고
    • HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2
    • Lubben, N. B., D. A. Sahlender, A. M. Motley, P. J. Lehner, P. Benaroch, and M. S. Robinson. 2007. HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2. Mol. Biol. Cell 18:3351-3365.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 3351-3365
    • Lubben, N.B.1    Sahlender, D.A.2    Motley, A.M.3    Lehner, P.J.4    Benaroch, P.5    Robinson, M.S.6
  • 54
    • 0037228216 scopus 로고    scopus 로고
    • The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4
    • DOI 10.1128/JVI.77.2.1427-1440.2003
    • Mansouri, M., E. Bartee, K. Gouveia, B. T. Hovey Nerenberg, J. Barrett, L. Thomas, G. Thomas, G. McFadden, and K. Fruh. 2003. The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4. J. Virol. 77:1427-1440. (Pubitemid 36055564)
    • (2003) Journal of Virology , vol.77 , Issue.2 , pp. 1427-1440
    • Mansouri, M.1    Bartee, E.2    Gouveia, K.3    Hovey Nerenberg, B.T.4    Barrett, J.5    Thomas, L.6    Thomas, G.7    McFadden, G.8    Fruh, K.9
  • 55
    • 34548482956 scopus 로고    scopus 로고
    • The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting
    • Mardones, G. A., P. V. Burgos, D. A. Brooks, E. Parkinson-Lawrence, R. Mattera, and J. S. Bonifacino. 2007. The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting. Mol. Biol. Cell 18:3486-3501.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 3486-3501
    • Mardones, G.A.1    Burgos, P.V.2    Brooks, D.A.3    Parkinson-Lawrence, E.4    Mattera, R.5    Bonifacino, J.S.6
  • 56
    • 0032012456 scopus 로고    scopus 로고
    • A novel human WD protein, h-βTrCP, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif
    • Margottin, F., S. P. Bour, H. Durand, L. Selig, S. Benichou, V. Richard, D. Thomas, K. Strebel, and R. Benarous. 1998. A novel human WD protein, h-βTrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif. Mol. Cell 1:565-574. (Pubitemid 128374692)
    • (1998) Molecular Cell , vol.1 , Issue.4 , pp. 565-574
    • Margottin, F.1    Bour, S.P.2    Durand, H.3    Selig, L.4    Benichou, S.5    Richard, V.6    Thomas, D.7    Strebel, K.8    Benarous, R.9
  • 57
    • 0027315870 scopus 로고
    • CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals
    • Mariani, R., and J. Skowronski. 1993. CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals. Proc. Natl. Acad. Sci. USA 90:5549-5553.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5549-5553
    • Mariani, R.1    Skowronski, J.2
  • 58
    • 33846821642 scopus 로고    scopus 로고
    • Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway
    • McNatt, M. W., I. McKittrick, M. West, and G. Odorizzi. 2007. Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway. Mol. Biol. Cell 18:697-706.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 697-706
    • McNatt, M.W.1    McKittrick, I.2    West, M.3    Odorizzi, G.4
  • 59
    • 0028006247 scopus 로고
    • The human immunodeficiency virus-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages
    • Miller, M. D., M. T. Warmerdam, I. Gaston, W. C. Greene, and M. B. Feinberg. 1994. The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J. Exp. Med. 179:101-113.
    • (1994) J. Exp. Med. , vol.179 , pp. 101-113
    • Miller, M.D.1    Warmerdam, M.T.2    Gaston, I.3    Greene, W.C.4    Feinberg, M.B.5
  • 60
    • 33846807370 scopus 로고    scopus 로고
    • Characterization of multiple multivesicular body sorting determinants within Sna3: A role for the ubiquitin ligase Rsp5
    • Oestreich, A. J., M. Aboian, J. Lee, I. Azmi, J. Payne, R. Issaka, B. A. Davies, and D. J. Katzmann. 2007. Characterization of multiple multivesicular body sorting determinants within Sna3: a role for the ubiquitin ligase Rsp5. Mol. Biol. Cell 18:707-720.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 707-720
    • Oestreich, A.J.1    Aboian, M.2    Lee, J.3    Azmi, I.4    Payne, J.5    Issaka, R.6    Davies, B.A.7    Katzmann, D.J.8
  • 61
    • 0033515427 scopus 로고    scopus 로고
    • Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes
    • Piguet, V., F. Gu, M. Foti, N. Demaurex, J. Gruenberg, J. L. Carpentier, and D. Trono. 1999. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes. Cell 97:63-73. (Pubitemid 29165890)
    • (1999) Cell , vol.97 , Issue.1 , pp. 63-73
    • Piguet, V.1    Gu, F.2    Foti, M.3    Demaurex, N.4    Gruenberg, J.5    Carpentier, J.-L.6    Trono, D.7
  • 62
    • 33645414100 scopus 로고    scopus 로고
    • HIV-1 coreceptors and their inhibitors
    • Ray, N., and R. W. Doms. 2006. HIV-1 coreceptors and their inhibitors. Curr. Top. Microbiol. Immunol. 303:97-120.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.303 , pp. 97-120
    • Ray, N.1    Doms, R.W.2
  • 63
    • 0035903635 scopus 로고    scopus 로고
    • Sorting of proteins into multivesicular bodies: Ubiquitin-dependent and -independent targeting
    • DOI 10.1093/emboj/20.18.5176
    • Reggiori, F., and H. R. Pelham. 2001. Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting. EMBO J. 20:5176-5186. (Pubitemid 32910912)
    • (2001) EMBO Journal , vol.20 , Issue.18 , pp. 5176-5186
    • Reggiori, F.1    Pelham, H.R.B.2
  • 64
    • 0028200761 scopus 로고
    • Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4
    • Rhee, S. S., and J. W. Marsh. 1994. Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. J. Virol. 68:5156-5163. (Pubitemid 24226584)
    • (1994) Journal of Virology , vol.68 , Issue.8 , pp. 5156-5163
    • Rhee, S.S.1    Marsh, J.W.2
  • 65
    • 33745122662 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef: Adapting to intracellular trafficking pathways
    • Roeth, J. F., and K. L. Collins. 2006. Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways. Microbiol. Mol. Biol. Rev. 70:548-563.
    • (2006) Microbiol. Mol. Biol. Rev. , vol.70 , pp. 548-563
    • Roeth, J.F.1    Collins, K.L.2
  • 66
    • 10344258588 scopus 로고    scopus 로고
    • HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail
    • DOI 10.1083/jcb.200407031
    • Roeth, J. F., M. Williams, M. R. Kasper, T. M. Filzen, and K. L. Collins. 2004. HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail. J. Cell Biol. 167:903-913. (Pubitemid 39628112)
    • (2004) Journal of Cell Biology , vol.167 , Issue.5 , pp. 903-913
    • Roeth, J.F.1    Kasper, M.R.2    Filzen, T.M.3    Collins, K.L.4
  • 67
    • 0029989195 scopus 로고    scopus 로고
    • NEF-CD4 physical interaction sensed with the yeast two-hybrid system
    • DOI 10.1006/viro.1996.0130
    • Rossi, F., A. Gallina, and G. Milanesi. 1996. Nef-CD4 physical interaction sensed with the yeast two-hybrid system. Virology 217:397-403. (Pubitemid 26103630)
    • (1996) Virology , vol.217 , Issue.1 , pp. 397-403
    • Rossi, F.1    Gallina, A.2    Milanesi, G.3
  • 68
    • 0027968920 scopus 로고
    • The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells
    • Sanfridson, A., B. R. Cullen, and C. Doyle. 1994. The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells. J. Biol. Chem. 269:3917-3920.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3917-3920
    • Sanfridson, A.1    Cullen, B.R.2    Doyle, C.3
  • 69
    • 50849129910 scopus 로고    scopus 로고
    • HIV-1 Nef targets MHC-I and CD4 for degradation via a final common β-COP-dependent pathway in T cells
    • Schaefer, M. R., E. R. Wonderlich, J. F. Roeth, J. A. Leonard, and K. L. Collins. 2008. HIV-1 Nef targets MHC-I and CD4 for degradation via a final common β-COP-dependent pathway in T cells. PLoS Pathog. 4:e1000131.
    • (2008) PLoS Pathog. , vol.4
    • Schaefer, M.R.1    Wonderlich, E.R.2    Roeth, J.F.3    Leonard, J.A.4    Collins, K.L.5
  • 72
    • 23844471509 scopus 로고    scopus 로고
    • Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8αβ
    • DOI 10.1128/JVI.79.17.11422-11433.2005
    • Stove, V., I. Van de Walle, E. Naessens, E. Coene, C. Stove, J. Plum, and B. Verhasselt. 2005. Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8αβ. J. Virol. 79:11422-11433. (Pubitemid 41170683)
    • (2005) Journal of Virology , vol.79 , Issue.17 , pp. 11422-11433
    • Stove, V.1    Van De Walle, I.2    Naessens, E.3    Coene, E.4    Stove, C.5    Plum, J.6    Verhasselt, B.7
  • 73
    • 0035794535 scopus 로고    scopus 로고
    • Mechanism for down-regulation of CD28 by Nef
    • DOI 10.1093/emboj/20.7.1593
    • Swigut, T., N. Shohdy, and J. Skowronski. 2001. Mechanism for down-regulation of CD28 by Nef. EMBO J. 20:1593-1604. (Pubitemid 32299397)
    • (2001) EMBO Journal , vol.20 , Issue.7 , pp. 1593-1604
    • Swigut, T.1    Shohdy, N.2    Skowronski, J.3
  • 74
    • 0025748151 scopus 로고
    • Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1
    • Terwilliger, E. F., E. Langhoff, D. Gabuzda, E. Zazopoulos, and W. A. Haseltine. 1991. Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 88:10971-10975.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10971-10975
    • Terwilliger, E.F.1    Langhoff, E.2    Gabuzda, D.3    Zazopoulos, E.4    Haseltine, W.A.5
  • 75
    • 20544465126 scopus 로고    scopus 로고
    • Common principles in clathrin-mediated sorting at the Golgi and the plasma membrane
    • Traub, L. M. 2005. Common principles in clathrin-mediated sorting at the Golgi and the plasma membrane. Biochim. Biophys. Acta 1744:415-437.
    • (2005) Biochim. Biophys. Acta , vol.1744 , pp. 415-437
    • Traub, L.M.1
  • 76
    • 33750716106 scopus 로고    scopus 로고
    • Expression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surfaces of target cells and thereby enhances resistance to superinfection
    • DOI 10.1128/JVI.01556-06
    • Venzke, S., N. Michel, I. Allespach, O. T. Fackler, and O. T. Keppler. 2006. Expression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surfaces of target cells and thereby enhances resistance to superinfection. J. Virol. 80:11141-11152. (Pubitemid 44706554)
    • (2006) Journal of Virology , vol.80 , Issue.22 , pp. 11141-11152
    • Venzke, S.1    Michel, N.2    Allespach, I.3    Fackler, O.T.4    Keppler, O.T.5
  • 77
    • 34249042608 scopus 로고    scopus 로고
    • Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3
    • DOI 10.1083/jcb.200611063
    • Wang, X., R. Herr, W. Chua, L. Lybarger, E. Wiertz, and T. Hansen. 2007. Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3. J. Cell Biol. 177:613-624. (Pubitemid 46799833)
    • (2007) Journal of Cell Biology , vol.177 , Issue.4 , pp. 613-624
    • Wang, X.1    Herr, R.A.2    Chua, W.-J.3    Lybarger, L.4    Wiertz, E.J.H.J.5    Hansen, T.H.6
  • 78
    • 34248162393 scopus 로고    scopus 로고
    • Direct binding to Rsp5p regulates ubiquitination-independent vacuolar transport of Sna3p
    • Watson, H., and J. S. Bonifacino. 2007. Direct binding to Rsp5p regulates ubiquitination-independent vacuolar transport of Sna3p. Mol. Biol. Cell 18:1781-1789.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1781-1789
    • Watson, H.1    Bonifacino, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.