메뉴 건너뛰기




Volumn 125, Issue 3, 2015, Pages 908-917

Gut chemosensing mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; SOMATOSTATIN; GASTROINTESTINAL HORMONE;

EID: 84924070363     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI76309     Document Type: Review
Times cited : (194)

References (150)
  • 1
    • 84888199705 scopus 로고    scopus 로고
    • Enteroendocrine secretion of gut hormones in diabetes, obesity and after bariatric surgery
    • Holst J. Enteroendocrine secretion of gut hormones in diabetes, obesity and after bariatric surgery. Curr Opin Pharmacol. 2013;13(6):983-988.
    • (2013) Curr Opin Pharmacol. , vol.13 , Issue.6 , pp. 983-988
    • Holst, J.1
  • 2
    • 79954427764 scopus 로고    scopus 로고
    • Characterization of basal pseudopodlike processes in ileal and colonic pyy cells
    • Bohórquez D, Chandra R, Samsa L, Vigna S, Liddle R. Characterization of basal pseudopodlike processes in ileal and colonic PYY cells. J Mol Histol. 2011;42(1):3-13.
    • (2011) J Mol Histol. , vol.42 , Issue.1 , pp. 3-13
    • Bohórquez, D.1    Chandra, R.2    Samsa, L.3    Vigna, S.4    Liddle, R.5
  • 3
    • 79952315396 scopus 로고    scopus 로고
    • The g-protei n-coupled receptor gpr40 directly mediates long-chain fatty acidinduced secretion of cholecystokinin
    • Liou A, et al. The G-protei n-coupled receptor GPR40 directly mediates long-chain fatty acidinduced secretion of cholecystokinin. Gastroenterology. 2011;140(3):903-912.
    • (2011) Gastroenterology. , vol.140 , Issue.3 , pp. 903-912
    • Liou, A.1
  • 4
    • 58149464981 scopus 로고    scopus 로고
    • Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine k cells
    • Parker H, Habib A, Rogers G, Gribble F, Reimann F. Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells. Diabetologia. 2009;52(2):289-298.
    • (2009) Diabetologia. , vol.52 , Issue.2 , pp. 289-298
    • Parker, H.1    Habib, A.2    Rogers, G.3    Gribble, F.4    Reimann, F.5
  • 5
    • 56449093424 scopus 로고    scopus 로고
    • Glucose sensing in l cells: A primary cell study
    • Reimann F, et al. Glucose sensing in L cells: a primary cell study. Cell Metab. 2008;8(6):532-539.
    • (2008) Cell Metab. , vol.8 , Issue.6 , pp. 532-539
    • Reimann, F.1
  • 6
    • 84862743498 scopus 로고    scopus 로고
    • Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
    • Habib A, et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology. 2012;153(7):3054-3065.
    • (2012) Endocrinology. , vol.153 , Issue.7 , pp. 3054-3065
    • Habib, A.1
  • 7
    • 84870225450 scopus 로고    scopus 로고
    • A major lineage of enteroendocrine cells coexpress cck, secretin, gip, glp-1, pyy, and neurotensin but not somatostatin
    • Egerod K, et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology. 2012;153(12):5782-5795.
    • (2012) Endocrinology. , vol.153 , Issue.12 , pp. 5782-5795
    • Egerod, K.1
  • 9
    • 0020501561 scopus 로고
    • Endocrine cells in human intestine: An immunocytochemical study
    • Sjölund K, Sandén G, Håkanson R, Sundler F. Endocrine cells in human intestine: an immunocytochemical study. Gastroenterology. 1983;85(5):1120-1130.
    • (1983) Gastroenterology. , vol.85 , Issue.5 , pp. 1120-1130
    • Sjölund, K.1    Sandén, G.2    Håkanson, R.3    Sundler, F.4
  • 10
    • 84924069033 scopus 로고    scopus 로고
    • Cross-species comparison of genes related to nutrient sensing mechanisms expressed along the intestine
    • van der Wielen N, et al. Cross-species comparison of genes related to nutrient sensing mechanisms expressed along the intestine. PLoS One. 2014;9(9):e107531.
    • (2014) PLoS One. , vol.9 , Issue.9 , pp. e107531
    • Van Der Wielen, N.1
  • 11
    • 0032552112 scopus 로고    scopus 로고
    • The stomach is a source of leptin
    • Bado A, et al. The stomach is a source of leptin. Nature. 1998;394(6695):790-793.
    • (1998) Nature. , vol.394 , Issue.6695 , pp. 790-793
    • Bado, A.1
  • 12
    • 84874996532 scopus 로고    scopus 로고
    • A review on gastric leptin: The exocrine secretion of a gastric hormone
    • Cammisotto P, Bendayan M. A review on gastric leptin: the exocrine secretion of a gastric hormone. Anat Cell Biol. 2012;45(1):1-16.
    • (2012) Anat Cell Biol. , vol.45 , Issue.1 , pp. 1-16
    • Cammisotto, P.1    Bendayan, M.2
  • 13
    • 0006525096 scopus 로고    scopus 로고
    • Expression of leptin and leptin receptor isoforms in the human stomach
    • Mix H, et al. Expression of leptin and leptin receptor isoforms in the human stomach. Gut. 2000;47(4):481-486.
    • (2000) Gut. , vol.47 , Issue.4 , pp. 481-486
    • Mix, H.1
  • 14
    • 0025830648 scopus 로고
    • Regulation of intestinal proglucagonderived peptide secretion by intestinal regulatory peptides
    • Brubaker P. Regulation of intestinal proglucagonderived peptide secretion by intestinal regulatory peptides. Endocrinology. 1991;128(6):3175-3182.
    • (1991) Endocrinology. , vol.128 , Issue.6 , pp. 3175-3182
    • Brubaker, P.1
  • 15
  • 16
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormonereleasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date Y,et al Ghrelin, a novel growth hormonereleasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans Endocr inology. 2000, 141, 11, 4255-4261.
    • (2000) Endocr Inology. , vol.141 , Issue.11 , pp. 4255-4261
    • Date, Y.1
  • 17
  • 18
    • 84863962816 scopus 로고    scopus 로고
    • Ghrelin's second life: From appetite stimulator to glucose regulator
    • Verhulst PJ, Depoortere I. Ghrelin's second life: from appetite stimulator to glucose regulator. World J Gastroenterol. 2012;18(25):3183-3195.
    • (2012) World J Gastroenterol. , vol.18 , Issue.25 , pp. 3183-3195
    • Verhulst, P.J.1    Depoortere, I.2
  • 19
    • 84891852494 scopus 로고    scopus 로고
    • Jejunal leptin-pi3k signaling lowers glucose production
    • Rasmussen BA, et al. Jejunal leptin-PI3K signaling lowers glucose production. Cell Metab. 2014;19(1):155-161.
    • (2014) Cell Metab. , vol.19 , Issue.1 , pp. 155-161
    • Rasmussen, B.A.1
  • 20
    • 84904985324 scopus 로고    scopus 로고
    • Insulin-like peptide 5 is an orexigenic gastrointestinal hormone
    • Grosse J, et al. Insulin-like peptide 5 is an orexigenic gastrointestinal hormone. Proc Natl Acad Sci U S A. 2014;111(30):11133-11138.
    • (2014) Proc Natl Acad Sci U S A. , vol.111 , Issue.30 , pp. 11133-11138
    • Grosse, J.1
  • 21
    • 0026510891 scopus 로고
    • Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man
    • Eissele R, et al. Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur J Clin Invest. 1992;22(4):238-291.
    • (1992) Eur J Clin Invest. , vol.22 , Issue.4 , pp. 238-291
    • Eissele, R.1
  • 22
    • 33846574365 scopus 로고    scopus 로고
    • Peptide YY: A neuroendocrine neighbor of note
    • Cox HM. Peptide YY: a neuroendocrine neighbor of note. Peptides. 2007;28(2):345-351.
    • (2007) Peptides. , vol.28 , Issue.2 , pp. 345-351
    • Cox, H.M.1
  • 23
    • 0016764430 scopus 로고
    • Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: An immunohistochemical and immunochemical study
    • Larsson L, Holst J, Hå kanson R, Sundler F. Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: an immunohistochemical and immunochemical study. Histochemistry. 1975;44(4):281-290.
    • (1975) Histochemistry. , vol.44 , Issue.4 , pp. 281-290
    • Larsson, L.1    Holst, J.2    Håkanson, R.3    Sundler, F.4
  • 24
    • 84896341216 scopus 로고    scopus 로고
    • An enteroendocrine cellenteric glia connection revealed by 3d electron microscopy
    • Bohórquez D, et al. An enteroendocrine cellenteric glia connection revealed by 3D electron microscopy. PLoS One. 2014;9(2):e89881.
    • (2014) PLoS One. , vol.9 , Issue.2 , pp. e89881
    • Bohórquez, D.1
  • 25
    • 79951648986 scopus 로고    scopus 로고
    • Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic ca2+ and camp
    • Tolhurst G, et al. Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP. Endocrinology. 2011;152(2):405-413.
    • (2011) Endocrinology. , vol.152 , Issue.2 , pp. 405-413
    • Tolhurst, G.1
  • 26
    • 51449117395 scopus 로고    scopus 로고
    • Effects of mid-jejunal compared to duodenal glucose infusion on peptide hormone release and appetite in healthy men
    • Chaikomin R, et al. Effects of mid-jejunal compared to duodenal glucose infusion on peptide hormone release and appetite in healthy men. Regul Pept. 2008;150(1):38-42.
    • (2008) Regul Pept. , vol.150 , Issue.1 , pp. 38-42
    • Chaikomin, R.1
  • 27
    • 0030007475 scopus 로고    scopus 로고
    • Oral glucose ingestion stimulates cholecystokinin release in normal subjects and patient s with non-insulin-dependent diabetes mellitus
    • Hasegawa H, et al. Oral glucose ingestion stimulates cholecystokinin release in normal subjects and patient s with non-insulin-dependent diabetes mellitus. Metabolism. 1996;45(2):196-202.
    • (1996) Metabolism. , vol.45 , Issue.2 , pp. 196-202
    • Hasegawa, H.1
  • 28
    • 18444394018 scopus 로고    scopus 로고
    • Effects of small intestinal and gastric glucose administration on the suppression of plasma ghrelin concentrations in healthy older men and women
    • Parker BA, Doran S, Wishart J, Horowitz M, Chapman IM. Effects of small intestinal and gastric glucose administration on the suppression of plasma ghrelin concentrations in healthy older men and women. Clin Endocrinol (Oxf). 2005;62(5):539-546.
    • (2005) Clin Endocrinol (Oxf). , vol.62 , Issue.5 , pp. 539-546
    • Parker, B.A.1    Doran, S.2    Wishart, J.3    Horowitz, M.4    Chapman, I.M.5
  • 29
    • 0030898014 scopus 로고    scopus 로고
    • Release of glucagon-like peptide-1 (glp-1) by carbohydrates in the perfused rat ileum
    • Ritzel U, Fromme A, Ottleben M, Leonhardt U, Ramadori G. Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum. Acta Diabetol. 1997;34(1):18-21.
    • (1997) Acta Diabetol. , vol.34 , Issue.1 , pp. 18-21
    • Ritzel, U.1    Fromme, A.2    Ottleben, M.3    Leonhardt, U.4    Ramadori, G.5
  • 30
    • 0025116147 scopus 로고
    • Relat ionship between molecular structures of sugars and their ability to stimulate the release of glucagon-like peptide-1 from canine ileal loops
    • Shima K, Suda T, Nishimoto K, Yoshimoto S. Relat ionship between molecular structures of sugars and their ability to stimulate the release of glucagon-like peptide-1 from canine ileal loops. Acta Endocrinol (Copenh). 1990;123(4):464-470.
    • (1990) Acta Endocrinol (Copenh). , vol.123 , Issue.4 , pp. 464-470
    • Shima, K.1    Suda, T.2    Nishimoto, K.3    Yoshimoto, S.4
  • 31
    • 0018893741 scopus 로고
    • Evidence for preferential stimulation of gastric inhibitory polypeptide secretion in the rat by actively transported carbohydrates and their analogues
    • Sykes S, M organ L, English J, Marks V. Evidence for preferential stimulation of gastric inhibitory polypeptide secretion in the rat by actively transported carbohydrates and their analogues. J Endocrinol. 1980;85(2):201-207.
    • (1980) J Endocrinol. , vol.85 , Issue.2 , pp. 201-207
    • Sykes, S.1    Morgan, L.2    English, J.3    Marks, V.4
  • 32
    • 0141532690 scopus 로고    scopus 로고
    • A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the glutag cell line
    • Gribble F, Williams L, Simpson A, Reimann F. A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line. Diabetes. 2003;52(5):1147-1154.
    • (2003) Diabetes. , vol.52 , Issue.5 , pp. 1147-1154
    • Gribble, F.1    Williams, L.2    Simpson, A.3    Reimann, F.4
  • 33
    • 84866065884 scopus 로고    scopus 로고
    • Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion
    • Parker H, et al. Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion. Diabetologia. 2012;55(9):2445-2455.
    • (2012) Diabetologia. , vol.55 , Issue.9 , pp. 2445-2455
    • Parker, H.1
  • 34
    • 84555186977 scopus 로고    scopus 로고
    • Na(+)-d-glucose cotransporter sglt1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion
    • Gorboulev V, et al. Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes. 2012;61(1):187-196.
    • (2012) Diabetes. , vol.61 , Issue.1 , pp. 187-196
    • Gorboulev, V.1
  • 35
    • 84876519168 scopus 로고    scopus 로고
    • Lx4211 increases serum glucagonlike peptide 1 and peptide yy levels by reducing sodium/glucose cotransporter 1 (sglt1)-mediated absorption of intestinal glucose
    • Powell D, et al. LX4211 increases serum glucagonlike peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose. J Pharmacol Exp Ther. 2013;345(2):250-259.
    • (2013) J Pharmacol Exp Ther. , vol.345 , Issue.2 , pp. 250-259
    • Powell, D.1
  • 36
    • 81255157890 scopus 로고    scopus 로고
    • Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus
    • Stephens J, et al. Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus. Diabetes Res Clin Pra ct. 2011;94(2):199-206.
    • (2011) Diabetes Res Clin Pra Ct. , vol.94 , Issue.2 , pp. 199-206
    • Stephens, J.1
  • 37
    • 84900555168 scopus 로고    scopus 로고
    • Fructose stimulates glp-1 but not gip secretion in mice, rats, and humans
    • Kuhre R,et al Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans Am J Physiol Gastrointest Liver Physiol. 2014 306 7, G622-G630.
    • (2014) Am J Physiol Gastrointest Liver Physiol. , vol.306 , Issue.7 , pp. G622-G630
    • Kuhre, R.1
  • 38
    • 35448986920 scopus 로고    scopus 로고
    • Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1
    • Jang H, et al. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A. 2007;104(38):15069-15074.
    • (2007) Proc Natl Acad Sci U S A. , vol.104 , Issue.38 , pp. 15069-15074
    • Jang, H.1
  • 39
    • 35448995622 scopus 로고    scopus 로고
    • T1r3 and gustducin in gut sense sugars to regulate expression of na+-glucose cotransporter 1
    • Margolskee R, et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proc Natl Acad Sci U S A. 2007;104(38):15075-15080.
    • (2007) Proc Natl Acad Sci U S A. , vol.104 , Issue.38 , pp. 15075-15080
    • Margolskee, R.1
  • 40
    • 84888198946 scopus 로고    scopus 로고
    • Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes
    • Young R, et al. Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes. Diabetes. 2013;62(10):3532-3541.
    • (2013) Diabetes. , vol.62 , Issue.10 , pp. 3532-3541
    • Young, R.1
  • 41
    • 84865147548 scopus 로고    scopus 로고
    • Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery
    • Geraedts MC, et al. Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery. Am J Physiol Endocrinol Metab. 2012;303(4):E464-E474.
    • (2012) Am J Physiol Endocrinol Metab. , vol.303 , Issue.4 , pp. E464-E474
    • Geraedts, M.C.1
  • 42
    • 64749083079 scopus 로고    scopus 로고
    • Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo
    • Fujita Y, et al. Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo. Am J Physiol Endocrinol Metab. 2009;296(3):E473-E479.
    • (2009) Am J Physiol Endocrinol Metab. , vol.296 , Issue.3 , pp. E473-E479
    • Fujita, Y.1
  • 43
    • 67149121867 scopus 로고    scopus 로고
    • Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects
    • Ma J, et al. Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects. Am J Physiol Gastrointest Liver Physiol. 2009;296(4):G735-G739.
    • (2009) Am J Physiol Gastrointest Liver Physiol. , vol.296 , Issue.4 , pp. G735-G739
    • Ma, J.1
  • 44
    • 33748128913 scopus 로고    scopus 로고
    • Critical role for peptide yy in protein-mediated satiation and body-weight regulation
    • Batterham R, et al. Critical role for peptide YY in protein-mediated satiation and body-weight regulation. Cell Metab. 2006;4(3):223-233.
    • (2006) Cell Metab. , vol.4 , Issue.3 , pp. 223-233
    • Batterham, R.1
  • 45
    • 5644240984 scopus 로고    scopus 로고
    • Glutamine potently stimulates glucagon-like peptide-1 secretion from glutag cells
    • Reimann F, Williams L, da Silva Xavier G, Rutter G, Gribble F. Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells. Diabetologia. 2004;47(9):1592-1601.
    • (2004) Diabetologia. , vol.47 , Issue.9 , pp. 1592-1601
    • Reimann, F.1    Williams, L.2    Da Silva Xavier, G.3    Rutter, G.4    Gribble, F.5
  • 46
    • 58149373780 scopus 로고    scopus 로고
    • Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects
    • Greenfield J, et al. Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects. Am J Clin Nutr. 2009;89(1):106-113.
    • (2009) Am J Clin Nutr. , vol.89 , Issue.1 , pp. 106-113
    • Greenfield, J.1
  • 47
    • 84862560443 scopus 로고    scopus 로고
    • The regulation of k-And l-cell activity by glut2 an d the calciumsensing receptor casr in rat small intestine
    • Mace O, Schindler M, Patel S. The regulation of K-And L-cell activity by GLUT2 an d the calciumsensing receptor CasR in rat small intestine. J Physiol. 2012;590(pt 12):2917-2936.
    • (2012) J Physiol. , vol.590 , pp. 2917-2936
    • Mace, O.1    Schindler, M.2    Patel, S.3
  • 48
    • 84889093491 scopus 로고    scopus 로고
    • Seven transmembrane g protein-coupled receptor repertoire of gastric ghrelin cells
    • Engelstoft MS, et al. Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells. Mol Metab. 2013;2(4):376-392.
    • (2013) Mol Metab. , vol.2 , Issue.4 , pp. 376-392
    • Engelstoft, M.S.1
  • 49
    • 79955069352 scopus 로고    scopus 로고
    • The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to l-phenylalanine in acutely isolated intestinal i cells
    • Liou A, et al. The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to L-phenylalanine in acutely isolated intestinal I cells. Am J Physiol Gastrointest Liver Physiol. 2011;300(4):G538-G546.
    • (2011) Am J Physiol Gastrointest Liver Physiol. , vol.300 , Issue.4 , pp. G538-G546
    • Liou, A.1
  • 50
    • 80054787845 scopus 로고    scopus 로고
    • Umami receptor activation increases duodenal bicarbonate secretion via glucagonlike peptide-2 release in rats
    • Wang J, et al. Umami receptor activation increases duodenal bicarbonate secretion via glucagonlike peptide-2 release in rats. J Pharmacol Exp Ther. 2011;339(2):464-473.
    • (2011) J Pharmacol Exp Ther. , vol.339 , Issue.2 , pp. 464-473
    • Wang, J.1
  • 51
    • 84874040640 scopus 로고    scopus 로고
    • The g protein-coupled receptor family c group 6 subtype a (gprc6a) receptor is involved in amino acid-induced glucagon-like peptide-1 secreti on from glutag cells
    • Oya M, et al. The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secreti on from GLUTag cells. J Biol Chem. 2013;288(7):4513-4521.
    • (2013) J Biol Chem. , vol.288 , Issue.7 , pp. 4513-4521
    • Oya, M.1
  • 52
    • 0031750108 scopus 로고    scopus 로고
    • Peptones stimulate both the secretion of the incretin hormone glucagonlike peptide 1 and the transcription of the p roglucagon gene
    • Cordier-Bussat M, et al. Peptones stimulate both the secretion of the incretin hormone glucagonlike peptide 1 and the transcription of the p roglucagon gene. Diabetes. 1998;47(7):1038-1045.
    • (1998) Diabetes. , vol.47 , Issue.7 , pp. 1038-1045
    • Cordier-Bussat, M.1
  • 53
    • 0034812998 scopus 로고    scopus 로고
    • A human cellular model for studying the regulation of glucagonlike peptide-1 secretion
    • Reimer R, et al. A human cellular model for studying the regulation of glucagonlike peptide-1 secretion. Endocrinology. 2001;142(10):4522-4528.
    • (2001) Endocrinology. , vol.142 , Issue.10 , pp. 4522-4528
    • Reimer, R.1
  • 54
    • 79955559414 scopus 로고    scopus 로고
    • Protein hydrolysate-induced cholecystokinin secretion from enteroendocrine cells is indirectly mediated by the intestinal oligopeptide transporter pept1
    • Liou A, et al. Protein hydrolysate-induced cholecystokinin secretion from enteroendocrine cells is indirectly mediated by the intestinal oligopeptide transporter PepT1. Am J Physiol Gastroin test Liver Physiol. 2011;300(5):G895-G902.
    • (2011) Am J Physiol Gastroin Test Liver Physiol. , vol.300 , Issue.5 , pp. G895-G902
    • Liou, A.1
  • 56
    • 84888000680 scopus 로고    scopus 로고
    • Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor
    • Diakogiannaki E, et al. Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor. Diabetologia. 2 013;56(12):2688-2696.
    • (2013) Diabetologia. , vol.56 , Issue.12 , pp. 2688-2696
    • Diakogiannaki, E.1
  • 57
    • 34347389492 scopus 로고    scopus 로고
    • Gpr93 activation by protein hydrolysate induces cck transcription and secretion in stc-1 cells
    • Choi S, et al. GPR93 activation by protein hydrolysate induces CCK transcription and secretion in STC-1 cells. Am J Physiol Gastrointest Liver Physiol. 2007;292(5):G1366-G1375.
    • (2007) Am J Physiol Gastrointest Liver Physiol. , vol.292 , Issue.5 , pp. G1366-G1375
    • Choi, S.1
  • 58
    • 0027227370 scopus 로고
    • Glucagon-like peptide-17-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: Acute post-prandial and 24-h secretio n patterns
    • Elliott R, et al. Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretio n patterns. J Endocrinol. 1993;138(1):159-166.
    • (1993) J Endocrinol. , vol.138 , Issue.1 , pp. 159-166
    • Elliott, R.1
  • 59
    • 0021905218 scopus 로고
    • Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, an d relationship to gallbladder contraction
    • Liddle R, Goldfine I, Rosen M, Taplitz R, Williams J. Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, an d relationship to gallbladder contraction. J Clin Invest. 1985;75(4):1144-1152.
    • (1985) J Clin Invest. , vol.75 , Issue.4 , pp. 1144-1152
    • Liddle, R.1    Goldfine, I.2    Rosen, M.3    Taplitz, R.4    Williams, J.5
  • 60
    • 0023789380 scopus 로고
    • Further characterisation of the 'ileal brake' reflex in man-Effect of ileal infusion of partia l digests of fat, protein, and starch on jejunal motility and release of neurotensin, enteroglucagon, and peptide yy
    • Spiller R, et al. Further characterisation of the 'ileal brake' reflex in man-effect of ileal infusion of partia l digests of fat, protein, and starch on jejunal motility and release of neurotensin, enteroglucagon, and peptide YY. Gut. 1988;29(8):1042-1051.
    • (1988) Gut. , vol.29 , Issue.8 , pp. 1042-1051
    • Spiller, R.1
  • 61
    • 13444263540 scopus 로고    scopus 로고
    • Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through gpr120
    • Hirasawa A, et al. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med. 2005;11(1):90-94.
    • (2005) Nat Med. , vol.11 , Issue.1 , pp. 90-94
    • Hirasawa, A.1
  • 62
    • 42449126696 scopus 로고    scopus 로고
    • A role for intes tinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagonlike peptide-1 and glucose-dependent insulinotropic peptide release
    • Chu Z, et al. A role for intes tinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagonlike Peptide-1 and glucose-dependent insulinotropic Peptide release. Endocrinology. 2008;149(5):2038-2047.
    • (2008) Endocrinology. , vol.149 , Issue.5 , pp. 2038-2047
    • Chu, Z.1
  • 63
    • 65549142522 scopus 로고    scopus 로고
    • Gpr119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine l-cell
    • Lauffer L, Iakoubov R, Brubaker P. GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell. Diabetes. 2009;58(5):1058-1066.
    • (2009) Diabetes. , vol.58 , Issue.5 , pp. 1058-1066
    • Lauffer, L.1    Iakoubov, R.2    Brubaker, P.3
  • 64
    • 52749098923 scopus 로고    scopus 로고
    • Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion
    • Edfalk S, Steneberg O, Edlund H. Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes. 2008;57(9):2280-2287.
    • (2008) Diabetes. , vol.57 , Issue.9 , pp. 2280-2287
    • Edfalk, S.1    Steneberg, O.2    Edlund, H.3
  • 65
    • 80955180014 scopus 로고    scopus 로고
    • Free fatty acid receptors ffar1 and gpr120 as novel therapeutic targets for metabolic disorders
    • Hara T, Hirasawa A, Ichimura A, Kimura I, Tsujimoto G. Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders. J Pharm Sci. 2011;100(9):3594-3601.
    • (2011) J Pharm Sci. , vol.100 , Issue.9 , pp. 3594-3601
    • Hara, T.1    Hirasawa, A.2    Ichimura, A.3    Kimura, I.4    Tsujimoto, G.5
  • 66
    • 84877763148 scopus 로고    scopus 로고
    • Co-localisation and secretion of glucagon-like peptide 1 and peptide yy from primary cultured human l cells
    • Ha bib A, Richards P, Rogers G, Reimann F, Gribble F. Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells. Diabetologia. 2013;56(6):1413-1416.
    • (2013) Diabetologia. , vol.56 , Issue.6 , pp. 1413-1416
    • Habib, A.1    Richards, P.2    Rogers, G.3    Reimann, F.4    Gribble, F.5
  • 67
    • 80052521074 scopus 로고    scopus 로고
    • 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
    • Hansen K, et al. 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. J Clin Endocrinol Metab. 2011;96(9):E1409-E1417.
    • (2011) J Clin Endocrinol Metab. , vol.96 , Issue.9 , pp. E1409-E1417
    • Hansen, K.1
  • 68
    • 77956397360 scopus 로고    scopus 로고
    • Peptide yy is critical for acylethanolamine receptor gpr119-induced activation of gastrointestinal mucosal responses
    • Cox H, et al. Peptide YY is critical for acylethanolamine receptor Gpr119-induced activation of gastrointestinal mucosal responses. Cell Metab. 2010;11(6):532-542.
    • (2010) Cell Metab. , vol.11 , Issue.6 , pp. 532-542
    • Cox, H.1
  • 69
    • 33644627958 scopus 로고    scopus 로고
    • Deorphanization of a g proteincoupled receptor for ole oylethanolamide and its use in the discovery of small-molecule hypophagic agents
    • Overton H, et al. Deorphanization of a G proteincoupled receptor for ole oylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 2006;3(3):167-175.
    • (2006) Cell Metab. , vol.3 , Issue.3 , pp. 167-175
    • Overton, H.1
  • 70
    • 0028575660 scopus 로고
    • Activation of proglucag on gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line
    • Drucker D, Jin T, Asa S, Young T, Brubaker P. Activation of proglucag on gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line. Mol Endocrinol. 1994;8(12):1646-1655.
    • (1994) Mol Endocrinol. , vol.8 , Issue.12 , pp. 1646-1655
    • Drucker, D.1    Jin, T.2    Asa, S.3    Young, T.4    Brubaker, P.5
  • 71
    • 58249117850 scopus 로고    scopus 로고
    • Epac is involved in camp-stimulated proglucagon expres sion and hormone production but not hormone secretion in pancreatic alpha-And intestinal l-cell lines
    • Islam D, et al. Epac is involved in cAMP-stimulated proglucagon expres sion and hormone production but not hormone secretion in pancreatic alpha-And intestinal L-cell lines. Am J Physiol Endocrinol Metab. 2009;296(1):E174-E181.
    • (2009) Am J Physiol Endocrinol Metab. , vol.296 , Issue.1 , pp. E174-E181
    • Islam, D.1
  • 72
    • 34548487959 scopus 로고    scopus 로고
    • Cyclic amp triggers glucagonlike peptide-1 secretion from the glutag enteroendocrine cell line
    • Simpson A, et al. Cyclic AMP triggers glucagonlike peptide-1 secretion from the GLUTag enteroendocrine cell line. Diabetologia. 2007;50(10):2181-2189.
    • (2007) Diabetologia. , vol.50 , Issue.10 , pp. 2181-2189
    • Simpson, A.1
  • 73
    • 84863307279 scopus 로고    scopus 로고
    • Effects of jnj-38431055, a novel gpr119 receptor agonist, in rand omized, double-blind, placebo-controlled studies in subjects with type 2 diabetes
    • Katz L, et al. Effects of JNJ-38431055, a novel GPR119 receptor agonist, in rand omized, double-blind, placebo-controlled studies in subjects with type 2 diabetes. Diabetes Obes Metab. 2012;14(8):709-716.
    • (2012) Diabetes Obes Metab. , vol.14 , Issue.8 , pp. 709-716
    • Katz, L.1
  • 74
    • 84867175373 scopus 로고    scopus 로고
    • Role of fatty acid transport protein 4 in oleic acid-indu ced glucagon-like peptide-1 secretion from murine intestinal l cells
    • Poreba M, et al. Role of fatty acid transport protein 4 in oleic acid-indu ced glucagon-like peptide-1 secretion from murine intestinal L cells. Am J Physiol Endocrinol Metab. 2012;303(7):E899-E907.
    • (2012) Am J Physiol Endocrinol Metab. , vol.303 , Issue.7 , pp. E899-E907
    • Poreba, M.1
  • 75
    • 79953214920 scopus 로고    scopus 로고
    • Essential role for protein kinase c? in oleic acid-induced glucagon-like peptide-1 secretion in vivo in the rat
    • Iakoubov R, Ahmed A, Lauffer L, Bazinet R, Brubaker P. Essential role for protein kinase C? in oleic acid-induced glucagon-like peptide-1 secretion in vivo in the rat. Endocrinology. 2011;152(4):1244-1252.
    • (2011) Endocrinology. , vol.152 , Issue.4 , pp. 1244-1252
    • Iakoubov, R.1    Ahmed, A.2    Lauffer, L.3    Bazinet, R.4    Brubaker, P.5
  • 76
    • 33845562666 scopus 로고    scopus 로고
    • Pluronic l81 enhances triacylglycerol accumulation in the cytosol and inhibits chylomicron secretion
    • Fatma S, Yakubov R, Anwar K, Hussain M. Pluronic L81 enhances triacylglycerol accumulation in the cytosol and inhibits chylomicron secretion. J Lipid Res. 2006;47(11):2422-2 432.
    • (2006) J Lipid Res. , vol.47 , Issue.11 , pp. 2422-2432
    • Fatma, S.1    Yakubov, R.2    Anwar, K.3    Hussain, M.4
  • 77
    • 66449133688 scopus 로고    scopus 로고
    • Coingestion of acylglycerols differentially affects glucose-induced insulin secretion via glucose-dependent insulinotropic polypeptide in c57bl/6j mice
    • Shimotoyodome A, et al. Coingestion of acylglycerols differentially affects glucose-induced insulin secretion via glucose-dependent insulinotropic polypeptide in C57BL/6J mice. Endocrinology. 2009;150( 5):2118-2126.
    • (2009) Endocrinology. , vol.150 , Issue.5 , pp. 2118-2126
    • Shimotoyodome, A.1
  • 78
    • 84863466415 scopus 로고    scopus 로고
    • Chylomicron formation and secretion is required for lipid-stimulated release of incretins glp-1 and gip
    • Lu W, et al. Chylomicron formation and secretion is required for lipid-stimulated release of incretins GLP-1 and GIP. Lipids. 2012;47(6):571-580.
    • (2012) Lipids. , vol.47 , Issue.6 , pp. 571-580
    • Lu, W.1
  • 79
    • 84881263806 scopus 로고    scopus 로고
    • Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion
    • Chandra R, et al. Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion. J Clin Invest. 2013;123(8):3343-3352.
    • (2013) J Clin Invest. , vol.123 , Issue.8 , pp. 3343-3352
    • Chandra, R.1
  • 80
    • 70449722754 scopus 로고    scopus 로고
    • Role of mgat2 and dgat1 in the release of gut peptides after triglyceride ingestion
    • Okawa M,et al Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion Biochem Biophys Res Commun. 2009, 390, 3, 377-381.
    • (2009) Biochem Biophys Res Commun. , vol.390 , Issue.3 , pp. 377-381
    • Okawa, M.1
  • 81
    • 79951961905 scopus 로고    scopus 로고
    • Jtt-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses food intake and gastric emptying with the elevation of plasma peptide yy and glucagon-like peptide-1 in a diet ary fat-dependent manner
    • Hata T, et al. JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses food intake and gastric emptying with the elevation of plasma peptide YY and glucagon-like peptide-1 in a diet ary fat-dependent manner. J Pharmacol Exp Ther. 2011;336(3):850-856.
    • (2011) J Pharmacol Exp Ther. , vol.336 , Issue.3 , pp. 850-856
    • Hata, T.1
  • 82
    • 84872022090 scopus 로고    scopus 로고
    • Activation of enteroendocrine membrane progesterone receptors promotes incretin sec retion and improves glucose tolerance in mice
    • Flock G, Cao X, Maziarz M, Drucker D. Activation of enteroendocrine membrane progesterone receptors promotes incretin sec retion and improves glucose tolerance in mice. Diabetes. 2013;62(1):283-290.
    • (2013) Diabetes. , vol.62 , Issue.1 , pp. 283-290
    • Flock, G.1    Cao, X.2    Maziarz, M.3    Drucker, D.4
  • 83
    • 44749084540 scopus 로고    scopus 로고
    • Overexpression of il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice
    • Franckhauser S, et al. Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice. Diabetologia. 2008;51(7):1306-1316.
    • (2008) Diabetologia. , vol.51 , Issue.7 , pp. 1306-1316
    • Franckhauser, S.1
  • 84
    • 51349111709 scopus 로고    scopus 로고
    • Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle ppar? and ucp2 expression in rats
    • Holmes A, et al. Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPAR? and UCP2 expression in rats. J Endocrinol. 2008;198(2):367-374.
    • (2008) J Endocrinol. , vol.198 , Issue.2 , pp. 367-374
    • Holmes, A.1
  • 85
    • 9744247597 scopus 로고    scopus 로고
    • Activityinduced glp-1 release in lean and obese subjects
    • Adam T, Westerterp-Plantenga M. Activityinduced GLP-1 release in lean and obese subjects. Physiol Behav. 2004;83(3):459-466.
    • (2004) Physiol Behav. , vol.83 , Issue.3 , pp. 459-466
    • Adam, T.1    Westerterp-Plantenga, M.2
  • 86
    • 34250311663 scopus 로고    scopus 로고
    • Effects of exercise on gut peptides, energy intake and appetite
    • Martins C, Morgan L, Bloom S, Robertson M. Effects of exercise on gut peptides, energy intake and appetite. J Endocrinol. 2007;193(2):251-258.
    • (2007) J Endocrinol. , vol.193 , Issue.2 , pp. 251-258
    • Martins, C.1    Morgan, L.2    Bloom, S.3    Robertson, M.4
  • 87
    • 81255157471 scopus 로고    scopus 로고
    • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from l cells and alpha cells
    • Ellingsgaard H, et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med. 2011;17(11):1481-1489.
    • (2011) Nat Med. , vol.17 , Issue.11 , pp. 1481-1489
    • Ellingsgaard, H.1
  • 88
    • 84866125785 scopus 로고    scopus 로고
    • Rectal taurocholate increase s l cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers
    • Adrian T, et al. Rectal taurocholate increase s L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia. 2012;55(9):2343-2347.
    • (2012) Diabetologia. , vol.55 , Issue.9 , pp. 2343-2347
    • Adrian, T.1
  • 89
    • 84876248677 scopus 로고    scopus 로고
    • Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans
    • Wu T, et al. Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans. J Clin Endocrinol Metab. 2013;98(4):E718-E722.
    • (2013) J Clin Endocrinol Metab. , vol.98 , Issue.4 , pp. E718-E722
    • Wu, T.1
  • 90
    • 69749127975 scopus 로고    scopus 로고
    • Serum bile acids are higher in humans with prior gastric bypass: Potential contribution to improved glucose and lipid metabolism
    • Patti M, et al. Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity (Silver Spring). 2009;17(9):1671-1677.
    • (2009) Obesity (Silver Spring). , vol.17 , Issue.9 , pp. 1671-1677
    • Patti, M.1
  • 91
    • 84864394573 scopus 로고    scopus 로고
    • The role of bile after rouxen-y gastric bypass in promoting weight loss and improving glycaemic control
    • Pournaras D, et al. The role of bile after Rouxen-Y gastric bypass in promoting weight loss and improving glycaemic control. Endocrinology. 2012;153(8):3613-3619.
    • (2012) Endocrinology. , vol.153 , Issue.8 , pp. 3613-3619
    • Pournaras, D.1
  • 92
    • 83755220083 scopus 로고    scopus 로고
    • Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion
    • Parker H, et al. Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br J Pharmacol. 2012;165(2):414-423.
    • (2012) Br J Pharmacol. , vol.165 , Issue.2 , pp. 414-423
    • Parker, H.1
  • 93
    • 69149083245 scopus 로고    scopus 로고
    • Tgr5-mediated bile acid sensing controls glucose homeostasis
    • Thomas C, et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 2009;10(3):167-177.
    • (2009) Cell Metab. , vol.10 , Issue.3 , pp. 167-177
    • Thomas, C.1
  • 94
    • 84867581999 scopus 로고    scopus 로고
    • Somatostatin receptor 5 and cannabinoid receptor 1 activation inhibit secretion of glucose-dependent insulinotropic polypepti de from intestinal k cells in rodents
    • Moss C, et al. Somatostatin receptor 5 and cannabinoid receptor 1 activation inhibit secretion of glucose-dependent insulinotropic polypepti de from intestinal K cells in rodents. Diabetologia. 2012;55(11):3094-3103.
    • (2012) Diabetologia. , vol.55 , Issue.11 , pp. 3094-3103
    • Moss, C.1
  • 95
    • 0041859261 scopus 로고    scopus 로고
    • Inhibition of food intake in obese subjects by peptide yy3-36
    • Batterham RL, et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med. 2003;349(10):941-948.
    • (2003) N Engl J Med. , vol.349 , Issue.10 , pp. 941-948
    • Batterham, R.L.1
  • 96
    • 34147178061 scopus 로고    scopus 로고
    • Effect of cck-1 receptor blockade on ghrelin and pyy secretion in men
    • Degen L, et al. Effect of CCK-1 receptor blockade on ghrelin and PYY secretion in men. Am J Physiol Regul Integr Comp Physiol. 2007;292(4):R1391-R1399.
    • (2007) Am J Physiol Regul Integr Comp Physiol. , vol.292 , Issue.4 , pp. R1391-R1399
    • Degen, L.1
  • 97
    • 80053252842 scopus 로고    scopus 로고
    • Metabolomic linkage reveals functional interaction between glucosedependent insulinotropic polypeptide and ghrelin in humans
    • Rudovich NN, et al. Metabolomic linkage reveals functional interaction between glucosedependent insulinotropic polypeptide and ghrelin in humans. Am J Physiol Endocrinol Metab. 2011;301(4):E608-E617.
    • (2011) Am J Physiol Endocrinol Metab. , vol.301 , Issue.4 , pp. E608-E617
    • Rudovich, N.N.1
  • 98
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed F, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A. 2004;101(44):15718-15723.
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , Issue.44 , pp. 15718-15723
    • Backhed, F.1
  • 99
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature. 2006;444(7122):1022-1023.
    • (2006) Nature. , vol.444 , Issue.7122 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 100
    • 84883478660 scopus 로고    scopus 로고
    • Gut microbiota from twins discordant for obesity modulate metabolism in mice
    • Ridaura VK, et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science. 2013;341(6150):1241214.
    • (2013) Science. , vol.341 , Issue.6150 , pp. 1241214
    • Ridaura, V.K.1
  • 101
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-Associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh PJ,et al An obesity-Associated gut microbiome with increased capacity for energy harvest Nature. 2006 444 7122, 1027-1031.
    • (2006) Nature. , vol.444 , Issue.7122 , pp. 1027-1031
    • Turnbaugh, P.J.1
  • 102
    • 0038363378 scopus 로고    scopus 로고
    • The orphan g protein-coupled receptors gpr41 and gpr43 are activated by propionate and other short chain carboxylic acids
    • Brown A, et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem. 2003;278(13):11312-113 19.
    • (2003) J Biol Chem. , vol.278 , Issue.13 , pp. 11312-11319
    • Brown, A.1
  • 103
    • 0038491435 scopus 로고    scopus 로고
    • Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation
    • Le Poul E, et al. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem. 2003;278(28):25481-25489.
    • (2003) J Biol Chem. , vol.278 , Issue.28 , pp. 25481-25489
    • Le Poul, E.1
  • 104
    • 33646376658 scopus 로고    scopus 로고
    • Short-chain fatty acid receptor, gpr43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine
    • Karaki S, et al. Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res. 2006;324(3):353-360.
    • (2006) Cell Tissue Res. , vol.324 , Issue.3 , pp. 353-360
    • Karaki, S.1
  • 105
    • 41049090425 scopus 로고    scopus 로고
    • Expression of the short-chain fatty acid receptor, gpr43, in the human colon
    • Karaki S, et al. Expression of the short-chain fatty acid receptor, GPR43, in the human colon. J Mol Histol. 2008;39(2):135-142.
    • (2008) J Mol Histol. , vol.39 , Issue.2 , pp. 135-142
    • Karaki, S.1
  • 106
    • 70149102106 scopus 로고    scopus 로고
    • Expression of short-chain fatty acid receptor gpr41 in the human colon
    • Tazoe H, et al. Expression of short-chain fatty acid receptor GPR41 in the human colon. Biomed Res. 2009;30(3):149-156.
    • (2009) Biomed Res. , vol.30 , Issue.3 , pp. 149-156
    • Tazoe, H.1
  • 107
    • 84884693129 scopus 로고    scopus 로고
    • Gpr41/ffar3 and gpr43/ffar2 as cosensors for short-chain fatty acids in enteroendocrine cells vs ffar3 in enteric neuro ns and ffar2 in enteric leukocytes
    • Nøhr M, et al. GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neuro ns and FFAR2 in enteric leukocytes. Endocrinology. 2013;154(10):3552-3564.
    • (2013) Endocrinology. , vol.154 , Issue.10 , pp. 3552-3564
    • Nøhr, M.1
  • 108
    • 84856509724 scopus 로고    scopus 로고
    • Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the g-protein-coupled receptor ffar2
    • Tolhurst G, et al. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes. 2012;61(2):364-371.
    • (2012) Diabetes. , vol.61 , Issue.2 , pp. 364-371
    • Tolhurst, G.1
  • 109
    • 84864053102 scopus 로고    scopus 로고
    • Receptor-specific regulation of erk1/2 activation by members of the " free fatty acid receptor" family
    • Seljeset S, Siehler S. Receptor-specific regulation of ERK1/2 activation by members of the " free fatty acid receptor" family. J Recept Signal Transduct Res. 2012;32(4):196-201.
    • (2012) J Recept Signal Transduct Res. , vol.32 , Issue.4 , pp. 196-201
    • Seljeset, S.1    Siehler, S.2
  • 110
    • 59649088932 scopus 로고    scopus 로고
    • Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine l cell
    • Lim G, et al. Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell. Endocrinology. 2009;150(2):580-591.
    • (2009) Endocrinology. , vol.150 , Issue.2 , pp. 580-591
    • Lim, G.1
  • 111
    • 84924700879 scopus 로고    scopus 로고
    • The short chain fatty acid propionate stimulates glp-1 pyy secretion via free fatty acid receptor 2 in rodents [published online ahead of print august 11 2014]
    • Psichas A, et al. The short chain fatty acid propionate stimulates GLP-1 PYY secretion via free fatty acid receptor 2 in rodents [published online ahead of print August 11, 2014]. Int J Obes (Lond). doi:10.1038/ijo. 2014.153.
    • Int J Obes (Lond).
    • Psichas, A.1
  • 112
    • 84864491110 scopus 로고    scopus 로고
    • Duodenal enteroendocrine i-cells contain mrna transcripts encoding key endocannabinoid and fatty acid receptors
    • Sykaras A, Demenis C, Case R, McLaughlin J, Smith C. Duodenal enteroendocrine I-cells contain mRNA transcripts encoding key endocannabinoid and fatty acid receptors. PLoS One. 2012;7( 8):e42373.
    • (2012) PLoS One. , vol.7 , Issue.8 , pp. e42373
    • Sykaras, A.1    Demenis, C.2    Case, R.3    McLaughlin, J.4    Smith, C.5
  • 113
    • 84905235179 scopus 로고    scopus 로고
    • Minireview: Gut microbiota: The neglected endocrine organ
    • Clarke G, et al. Minireview: Gut microbiota: the neglected endocrine organ. Mol Endocrinol. 2014;28(8):1221-1238.
    • (2014) Mol Endocrinol. , vol.28 , Issue.8 , pp. 1221-1238
    • Clarke, G.1
  • 114
    • 84861978076 scopus 로고    scopus 로고
    • Host-gu t microbiota metabolic interactions
    • Nicholson JK, et al. Host-gu t microbiota metabolic interactions. Science. 2012;336(6086):1262-1267.
    • (2012) Science. , vol.336 , Issue.6086 , pp. 1262-1267
    • Nicholson, J.K.1
  • 115
    • 84912137874 scopus 로고    scopus 로고
    • Bacterial metabolite indole modulates incre tin secretion from intestinal enteroendocrine l-cells
    • Chimerel C, Emery E, Summers DK, Keyser U, Gribble FM, Reimann F. Bacterial metabolite indole modulates incre tin secretion from intestinal enteroendocrine L-cells. Cell Rep. 2014;9(4):1202-1208.
    • (2014) Cell Rep. , vol.9 , Issue.4 , pp. 1202-1208
    • Chimerel, C.1    Emery, E.2    Summers, D.K.3    Keyser, U.4    Gribble, F.M.5    Reimann, F.6
  • 116
    • 84894207845 scopus 로고    scopus 로고
    • Physiology and pharmacology of the enteroendocrine hormone glucagonlike peptide-2
    • Drucker DJ, Yusta B. Physiology and pharmacology of the enteroendocrine hormone glucagonlike peptide-2. Annu Rev Physiol. 2014;76:561-583.
    • (2014) Annu Rev Physiol. , vol.76 , pp. 561-583
    • Drucker, D.J.1    Yusta, B.2
  • 117
    • 34447505100 scopus 로고    scopus 로고
    • Enteroendocrine cells express functional toll-like receptors
    • Bogunovic M, et al. Enteroendocrine cells express functional Toll-like receptors. Am J Physiol Gastrointest Liver Physiol. 2007;292(6):G1770-G1783.
    • (2007) Am J Physiol Gastrointest Liver Physiol. , vol.292 , Issue.6 , pp. G1770-G1783
    • Bogunovic, M.1
  • 118
    • 33947667036 scopus 로고    scopus 로고
    • Activation of enteroendocrine cells via tlrs induces hormone, chemokine, and defensin secretion
    • Palazzo M, et al. Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion. J Immunol. 2007;178(7):4296-4303.
    • (2007) J Immunol. , vol.178 , Issue.7 , pp. 4296-4303
    • Palazzo, M.1
  • 119
    • 48249099626 scopus 로고    scopus 로고
    • Induction of pro-inflammatory programs in enteroendocrine cell s by the tolllike receptor agonists flagellin and bacterial lps
    • Selleri S, et al. Induction of pro-inflammatory programs in enteroendocrine cell s by the Tolllike receptor agonists flagellin and bacterial LPS. Int Immunol. 2008;20(8):961-970.
    • (2008) Int Immunol. , vol.20 , Issue.8 , pp. 961-970
    • Selleri, S.1
  • 120
    • 0038604293 scopus 로고    scopus 로고
    • Bacterial dna evokes epithelial il-8 productio n by a mapk-dependent nf-?b-independent pathway
    • Akhtar M, Watson JL, Nazli A, McKay DM. Bacterial DNA evokes epithelial IL-8 productio n by a MAPK-dependent, NF-?B-independent pathway. FASEB J. 2003;17(10):1319-1321.
    • (2003) FASEB J. , vol.17 , Issue.10 , pp. 1319-1321
    • Akhtar, M.1    Watson, J.L.2    Nazli, A.3    McKay, D.M.4
  • 121
    • 0038781673 scopus 로고    scopus 로고
    • Interferon augments the intracellular pathway for lipopolysaccharide (lps) recognition in human intestinal epithelial cells through coordinated up-regulation of lps uptake and expression of the intracellular toll-like recept or 4-md-2 complex
    • Suzuki M, Hisama tsu T, Podolsky DK. ?-Interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like recept or 4-MD-2 complex. Infect Immun. 2003;71(6):3503-3511.
    • (2003) Infect Immun. , vol.71 , Issue.6 , pp. 3503-3511
    • Suzuki, M.1    Hisamatsu, T.2    Podolsky, D.K.3
  • 122
    • 33645112510 scopus 로고    scopus 로고
    • Immune control of food intake: Enteroendocrine cells are regulated by cd4+ t lymphocytes during small intestinal inflammation
    • McDermott JR, et al. Immune control of food intake: enteroendocrine cells are regulated by CD4+ T lymphocytes during small intestinal inflammation. Gut. 2006;55(4):492-497.
    • (2006) Gut. , vol.55 , Issue.4 , pp. 492-497
    • McDermott, J.R.1
  • 123
    • 84859478593 scopus 로고    scopus 로고
    • Gproteincoupled receptors in intestinal chemosensation
    • Reimann F, Tolhurst G, Gribble F. G-proteincoupled receptors in intestinal chemosensation. Cell Metab. 2012;15(4):421-431.
    • (2012) Cell Metab. , vol.15 , Issue.4 , pp. 421-431
    • Reimann, F.1    Tolhurst, G.2    Gribble, F.3
  • 124
  • 125
    • 0036090456 scopus 로고    scopus 로고
    • Muscarinic receptors control postprandial release of glucagon-like peptide-1: In vivo and in vitro studies in rats
    • Anini Y, Hansotia T, Brubaker P. Muscarinic receptors control postprandial release of glucagon-like peptide-1: in vivo and in vitro studies in rats. Endocrinology. 2002;143(6):2420-2426.
    • (2002) Endocrinology. , vol.143 , Issue.6 , pp. 2420-2426
    • Anini, Y.1    Hansotia, T.2    Brubaker, P.3
  • 126
    • 0033996948 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide potently stimulates glucagon-like peptide-1 release in the isolated perfused rat ileum
    • Herrmann-Rin ke C, McGregor G, Göke B. Calcitonin gene-related peptide potently stimulates glucagon-like peptide-1 release in the isolated perfused rat ileum. Peptides. 2000;21(3):431-437.
    • (2000) Peptides. , vol.21 , Issue.3 , pp. 431-437
    • Herrmann-Rinke, C.1    McGregor, G.2    Göke, B.3
  • 127
    • 0020458023 scopus 로고
    • Bombesin: Action on gut hormones and calcium in man
    • Ghatei M, et al. Bombesin: action on gut hormones and calcium in man. J Clin Endocrinol Metab. 1982;54(5):980-985.
    • (1982) J Clin Endocrinol Metab. , vol.54 , Issue.5 , pp. 980-985
    • Ghatei, M.1
  • 128
    • 41149176081 scopus 로고    scopus 로고
    • International union of pharma cology. Lxviii. Mammalian bombesin receptors: Nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states
    • Jensen R, Battey J, Spindel E, Benya R. International Union of Pharma cology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states. Pharmacol Rev. 2008;60(1):1-42.
    • (2008) Pharmacol Rev. , vol.60 , Issue.1 , pp. 1-42
    • Jensen, R.1    Battey, J.2    Spindel, E.3    Benya, R.4
  • 129
    • 0033662673 scopus 로고    scopus 로고
    • Reduced glp-1 and insulin responses and glucose intolerance after gastric glucose in grp receptor-deleted mice
    • Persson K, et al. Reduc ed GLP-1 and insulin responses and glucose intolerance after gastric glucose in GRP receptor-deleted mice. Am J Physiol Endocrinol Metab. 2000;279(5):E956-E962.
    • (2000) Am J Physiol Endocrinol Metab. , vol.279 , Issue.5 , pp. E956-E962
    • Persson, K.1
  • 130
    • 0029782662 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-Activating polypeptide stimulates cholecystokinin secretion in stc-1 cells
    • Chang C, Chey W, Braggins L, Coy D, Chang T. Pituitary adenylate cyclase-Activating polypeptide stimulates cholecystokinin secretion in STC-1 cells. Am J Physiol. 1996;271(3):G516-G523.
    • (1996) Am J Physiol. , vol.271 , Issue.3 , pp. G516-G523
    • Chang, C.1    Chey, W.2    Braggins, L.3    Coy, D.4    Chang, T.5
  • 131
    • 0034048147 scopus 로고    scopus 로고
    • Pituitary adenylate cyclaseactivating polypeptide and its receptors: From structure to functions
    • Vaudry D, et al. Pituitary adenylate cyclaseactivating polypeptide and its receptors: from structure to functions. Pharmacol Rev. 2000;52(2):269-324.
    • (2000) Pharmacol Rev. , vol.52 , Issue.2 , pp. 269-324
    • Vaudry, D.1
  • 132
    • 0030011599 scopus 로고    scopus 로고
    • Galanin is a potent inhibitor of glucagonlike peptide-1 secretion from rat ileum
    • Herrmann-Rinke C, Hörsch D, McGregor G, Göke B. Galanin is a potent inhibitor of glucagonlike peptide-1 secretion from rat ileum. Peptides. 1996;17(4):571-576.
    • (1996) Peptides. , vol.17 , Issue.4 , pp. 571-576
    • Herrmann-Rinke, C.1    Hörsch, D.2    McGregor, G.3    Göke, B.4
  • 133
    • 0028786302 scopus 로고
    • Galanin inhibits cholecystokinin secretion in stc-1 cells
    • Chang C, Chey W, Coy D, Chang T. Galanin inhibits cholecystokinin secretion in STC-1 cells. Biochem Biophys Res Commun. 1995;216(1):20-25.
    • (1995) Biochem Biophys Res Commun. , vol.216 , Issue.1 , pp. 20-25
    • Chang, C.1    Chey, W.2    Coy, D.3    Chang, T.4
  • 134
    • 2642611149 scopus 로고    scopus 로고
    • Galanin inhibits glucagon-like peptide-1 secretion through pertussi s toxinsensitive g protein and atp-dependent potassium channels in rat ileal l-cells
    • Saïfia S, et al. Galanin inhibits glucagon-like peptide-1 secretion through pertussi s toxinsensitive G protein and ATP-dependent potassium channels in rat ileal L-cells. J Endocrinol. 1998;157(1):33-41.
    • (1998) J Endocrinol. , vol.157 , Issue.1 , pp. 33-41
    • Saïfia, S.1
  • 135
    • 0024365476 scopus 로고
    • Inhibitory effect of galanin on postprandial gastrointestinal motility and gut hormone release in humans
    • Bauer F, et al. Inhibitory effect of galanin on postprandial gastrointestinal motility and gut hormone release in humans. Gastroenterology. 1989;97(2):260-264.
    • (1989) Gastroenterology. , vol.97 , Issue.2 , pp. 260-264
    • Bauer, F.1
  • 136
    • 84877926067 scopus 로고    scopus 로고
    • Circulating galanin levels are increased in patients with gestational diabetes mellitus
    • Fang P, Bo P, Shi M, Yu M, Zhang Z. Circulating galanin levels are increased in patients with gestational diabetes mellitus. Clin Biochem. 2013;46(9):831-833.
    • (2013) Clin Biochem. , vol.46 , Issue.9 , pp. 831-833
    • Fang, P.1    Bo, P.2    Shi, M.3    Yu, M.4    Zhang, Z.5
  • 137
    • 14644439855 scopus 로고    scopus 로고
    • Positive correlation of galanin with glucose in type 2 diabetes
    • Legakis I, Mantzouridis T, Mountokalakis T. Positive correlation of galanin with glucose in type 2 diabetes. Diabetes Care. 2005;28(3):759-760.
    • (2005) Diabetes Care. , vol.28 , Issue.3 , pp. 759-760
    • Legakis, I.1    Mantzouridis, T.2    Mountokalakis, T.3
  • 138
    • 0037043150 scopus 로고    scopus 로고
    • Localisation of cannabinoid cb1) receptor immunoreactivity in the guinea pig and rat myenteric plexus
    • Coutts A, Irving A, Mackie K, Pertwee R, Anavi-Goffer S. Localisation of cannabinoid CB(1) receptor immunoreactivity in the guinea pig and rat myenteric plexus. J Comp Neurol. 2002;448(4):410-422.
    • (2002) J Comp Neurol. , vol.448 , Issue.4 , pp. 410-422
    • Coutts, A.1    Irving, A.2    Mackie, K.3    Pertwee, R.4    Anavi-Goffer, S.5
  • 139
    • 0030856768 scopus 로고    scopus 로고
    • Effects of cannabinoid receptor ligands on electrophysiological properties of myenteric neurones of the guineapig ileum
    • Ló pez-Redondo F, Lees G, Pertwee R. Effects of cannabinoid receptor ligands on electrophysiological properties of myenteric neurones of the guineapig ileum. Br J Pharmacol. 1997;122(2):330-334.
    • (1997) Br J Pharmacol. , vol.122 , Issue.2 , pp. 330-334
    • López-Redondo, F.1    Lees, G.2    Pertwee, R.3
  • 140
    • 84897883235 scopus 로고    scopus 로고
    • Identification and characterization of glp-1 receptor-expressing cells using a new transgenic mouse model
    • Richards P, et al. Identification and characterization of GLP-1 receptor-expressing cells using a new transgenic mouse model. Diabetes. 2014;63(4):1224-1233.
    • (2014) Diabetes. , vol.63 , Issue.4 , pp. 1224-1233
    • Richards, P.1
  • 141
    • 77952109949 scopus 로고    scopus 로고
    • Peripheral motor action of glucagon-like peptide-1 through enteric neuronal receptors
    • Amato A, et al. Peripheral motor action of glucagon-like peptide-1 through enteric neuronal receptors. Neurogastroenterol Motil. 2010;22(6):664-e203.
    • (2010) Neurogastroenterol Motil. , vol.22 , Issue.6 , pp. 664-e203
    • Amato, A.1
  • 142
    • 84867605838 scopus 로고    scopus 로고
    • Glucagon-like peptide 2 induces vasoactive intestinal polypeptide expression in enteric neurons via phophatidylinositol 3-kinase-? Signaling
    • de Heuvel E, Wallace L, Sharkey K, Sigalet D. Glucagon-like peptide 2 induces vasoactive intestinal polypeptide expression in enteric neurons via phophatidylinositol 3-kinase-? signaling. Am J Physiol Endocrinol Metab. 2012; 303(8):E994-E1005.
    • (2012) Am J Physiol Endocrinol Metab. , vol.303 , Issue.8 , pp. E994-E1005
    • De Heuvel, E.1    Wallace, L.2    Sharkey, K.3    Sigalet, D.4
  • 143
    • 0036135192 scopus 로고    scopus 로고
    • Vagal afferents innervating the gastrointestinal tract and ccka-receptor immunoreactivity
    • Patterson L, Zheng H, Berthoud H. Vagal afferents innervating the gastrointestinal tract and CCKA-receptor immunoreactivity. Anat Rec. 2002;266(1):10-20.
    • (2002) Anat Rec. , vol.266 , Issue.1 , pp. 10-20
    • Patterson, L.1    Zheng, H.2    Berthoud, H.3
  • 144
    • 0030870022 scopus 로고    scopus 로고
    • Analysis of the responses of myenteric neurons in the small intestine to chemical stimulation of the mucosa
    • Bertrand P,Kunze W,Bornstein J,Furness J,Smith M Analysis of the responses of myenteric neurons in the small intestine to chemical stimulation of the mucosa Am J Physiol. 1997 273 2): G422-G435.
    • (1997) Am J Physiol. , vol.273 , Issue.2 , pp. G422-G435
    • Bertrand, P.1    Kunze, W.2    Bornstein, J.3    Furness, J.4    Smith, M.5
  • 145
    • 0033151756 scopus 로고    scopus 로고
    • Characteristics of mucosally projecting myenteric neurones in the guinea-pig proximal colon
    • Neunlist M, Dobreva G, Schemann M. Characteristics of mucosally projecting myenteric neurones in the guinea-pig proximal colon. J Physiol. 1999;517(pt 2):533-546.
    • (1999) J Physiol. , vol.517 , pp. 533-546
    • Neunlist, M.1    Dobreva, G.2    Schemann, M.3
  • 146
    • 77951684976 scopus 로고    scopus 로고
    • Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats
    • Soret R, et al. Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats. Gastroenterology. 2010;138(5):1772-1782.
    • (2010) Gastroenterology. , vol.138 , Issue.5 , pp. 1772-1782
    • Soret, R.1
  • 148
    • 0033509334 scopus 로고    scopus 로고
    • Identification and characterization of glucoresponsive neurons in the enteric nervous system
    • Liu M, Seino S, Kirchgessner A. Identification and characterization of glucoresponsive neurons in the enteric nervous system. J Neurosci. 1999;19(23):10305-10317.
    • (1999) J Neurosci. , vol.19 , Issue.23 , pp. 10305-10317
    • Liu, M.1    Seino, S.2    Kirchgessner, A.3
  • 149
    • 84904249146 scopus 로고    scopus 로고
    • Nutrient-induced changes in the phenotype and function of the enteric nervous system
    • Neunlist M, Schemann M. Nutrient-induced changes in the phenotype and function of the enteric nervous system. J Physiol. 2014; 592(pt 14):2959-2965.
    • (2014) J Physiol. , vol.592 , pp. 2959-2965
    • Neunlist, M.1    Schemann, M.2
  • 150
    • 77953352917 scopus 로고    scopus 로고
    • Expression and function of the bile acid receptor gpbar1 (tgr5) in the murine enteric nervous system
    • Poole D, et al. Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system. Neurogastroenterol Motil. 2010;22(7):814-825.
    • (2010) Neurogastroenterol Motil. , vol.22 , Issue.7 , pp. 814-825
    • Poole, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.