Epac is involved in cAMP-stimulated proglucagon expression and hormone production but not hormone secretion in pancreatic α- And intestinal L-cell lines

American Journal of Physiology - Endocrinology and Metabolism

Volumn 296, Issue 1, 2009, Pages

  Islam, Diana ^a,b   Zhang, Nina ^d   Wang, Peixiang ^a   Li, Hang ^a   Brubaker, Patricia L ^b,c   Gaisano, Herbert Y ^b,c   Wang, Qinghua ^b,c,d   Jin, Tianru ^a,b,c,e  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b Department of Medicine ^*  (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d ST MICHAEL'S HOSPITAL   (Canada)

^e UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Exchange protein directly activated by adenosine 3 ,5 cyclic monophosphate; Glucagon; Glucagon like peptide 1; Protein kinase a

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CYCLIC AMP; FORSKOLIN; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; INSULIN; MESSENGER RNA; PEPTIDE HORMONE; PROGLUCAGON; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENDOCRINE CELL; HORMONE RELEASE; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; INSULIN RELEASE; INTESTINE CELL; PANCREAS ISLET ALPHA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENTEROENDOCRINE CELLS; FORSKOLIN; GLUCAGON-LIKE PEPTIDE 1; GLUCAGON-SECRETING CELLS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; PROGLUCAGON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 58249117850     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90419.2008     Document Type: Article

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