Hypermutable non-synonymous sites are under stronger negative selection

PLoS Genetics

Volumn 4, Issue 11, 2008, Pages

  Schmidt, Steffen ^a,b   Gerasimova, Anna ^c   Kondrashov, Fyodor A ^d   Adzuhbei, Ivan A ^a   Kondrashov, Alexey S ^c   Sunyaev, Shamil ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE;

ARTICLE; CHIMPANZEE; CODON; CONTROLLED STUDY; GENE MUTATION; GENETIC VARIABILITY; HUMAN; MOLECULAR GENETICS; MUTATION RATE; NONHUMAN; PHENOTYPE; ANIMAL; CPG ISLAND; GENETIC SELECTION; GENETICS; GENOME; HUMAN GENOME; MOLECULAR EVOLUTION; MUTATION; PAN TROGLODYTES;

PAN;

ANIMALS; CPG ISLANDS; EVOLUTION, MOLECULAR; GENOME; GENOME, HUMAN; HUMANS; MUTATION; PAN TROGLODYTES; SELECTION (GENETICS);

EID: 57149120515     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000281     Document Type: Article

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