Non-traditional cytokines: How catecholamines and adipokines influence macrophages in immunity, metabolism and the central nervous system

Cytokine

Volumn 72, Issue 2, 2015, Pages 210-219

  Barnes, Mark A ^a   Carson, Monica J ^a   Nair, Meera G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adipokine; Atherosclerosis; Dopamine; Macrophage; Resistin like molecules

Indexed keywords

ADIPOCYTOKINE; ADRENALIN; ALPHA ADRENERGIC RECEPTOR; ARGINASE 1; BETA ADRENERGIC RECEPTOR; CATECHOLAMINE; CHEMOKINE RECEPTOR CCR5; DOPAMINE; HISTONE DEACETYLASE 4; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; LEPTIN; LIPOPROTEIN; LIPOPROTEIN LIPASE; MONOCYTE CHEMOTACTIC PROTEIN 1; NORADRENALIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR; PROTEIN KINASE C; RESISTIN; ROSIGLITAZONE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE 3 MONOOXYGENASE; CYTOKINE; HORMONE;

ACUTE RESPIRATORY TRACT DISEASE; ADIPOGENESIS; ADRENERGIC SYSTEM; ANTIINFLAMMATORY ACTIVITY; ATHEROGENESIS; ATHEROSCLEROSIS; BURN; CELL MIGRATION; CENTRAL NERVOUS SYSTEM; CHOLESTEROL TRANSPORT; CYTOKINE PRODUCTION; DOWN REGULATION; ENDOTOXEMIA; FOAM CELL; HORMONE SYNTHESIS; HUMAN; IMMUNITY; IMMUNOMODULATION; INNATE IMMUNITY; LIPID STORAGE; LIPID TRANSPORT; MACROPHAGE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SEPSIS; SIGNAL TRANSDUCTION; TH2 CELL; THERMOGENESIS; WOUND HEALING; ANIMAL; CLASSIFICATION; IMMUNOLOGY; METABOLISM; NERVE TRACT; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ADIPOKINES; ANIMALS; BIOLOGICAL TRANSPORT; CATECHOLAMINES; CENTRAL NERVOUS SYSTEM; CYTOKINES; HORMONES; HUMANS; LIPOPROTEINS; MACROPHAGES; NEURAL PATHWAYS; RESISTIN; THERMOGENESIS;

EID: 84923786712     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2015.01.008     Document Type: Review

References (89)

1. Schulze J., Vogelgesang A., Dressel A. Catecholamines, steroids and immune alterations in ischemic stroke and other acute diseases. Aging Dis 2014, 5:327-339.
2. Andersson U., Tracey K.J. Neural reflexes in inflammation and immunity. J Exp Med 2012, 209:1057-1068.
3. Musso N.R., Brenci S., Setti M., Indiveri F., Lotti G. Catecholamine content and in vitro catecholamine synthesis in peripheral human lymphocytes. J Clin Endocrinol Metab 1996, 81:3553-3557.
4. Torres-Rosas R., Yehia G., Pena G., Mishra P., del Rocio Thompson-Bonilla M., Moreno-Eutimio M.A., et al. Dopamine mediates vagal modulation of the immune system by electroacupuncture. Nat Med 2014, 20:291-295.
5. Watkins L.R., Goehler L.E., Relton J.K., Tartaglia N., Silbert L., Martin D., et al. Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication. Neurosci Lett 1995, 183:27-31.
6. Bergquist J., Tarkowski A., Ekman R., Ewing A. Discovery of endogenous catecholamines in lymphocytes and evidence for catecholamine regulation of lymphocyte function via an autocrine loop. Proc Nat Acad Sci 1994, 91:12912-12916.
7. Offen D., Ziv I., Gorodin S., Barzilai A., Malik Z., Melamed E. Dopamine-induced programmed cell death in mouse thymocytes. Biochim Biophys Acta 1995, 31:171-177.
8. Brown S.W., Meyers R.T., Brennan K.M., Rumble J.M., Narasimhachari N., Perozzi E.F., et al. Catecholamines in a macrophage cell line. J Neuroimmunol 2003, 135:47-55.
9. Goridis C., Rohrer H. Specification of catecholaminergic and serotonergic neurons. Nat Rev Neurosci 2002, 3:531-541.
10. Perreault M.L., Hasbi A., O'Dowd B.F., George S.R. Heteromeric dopamine receptor signaling complexes: emerging neurobiology and disease relevance. Neuropsychopharmacology 2014, 39:156-168.
11. Dorn GW. Adrenergic signaling polymorphisms and their impact on cardiovascular disease, 2010.
12. Stanojevic S., Dimitrijevic M., Kustrimovic N., Mitic K., Vujic V., Leposavic G. Adrenal hormone deprivation affects macrophage catecholamine metabolism and beta2-adrenoceptor density, but not propranolol stimulation of tumour necrosis factor-alpha production. Exp Physiol 2013, 98:665-678.
13. Guo Y.P., Liu Y., Li J.B., Huang Y., Qi H.P., Xie J., et al. Chronic beta-adrenoceptor antagonists upregulate the rat alveolar macrophage adrenergic system through the beta1-subtype. Cell Physiol Biochem 2011, 28:315-322.
14. Pekarova M., Kralova J., Kubala L., Ciz M., Papezikova I., Macickova T., et al. Carvedilol and adrenergic agonists suppress the lipopolysaccharide-induced NO production in RAW 264.7 macrophages via the adrenergic receptors. J Physiol Pharmacol 2009, 60:143-150.
15. Bosmann M., Grailer J.J., Zhu K., Matthay M.A., Sarma J.V., Zetoune F.S., et al. Anti-inflammatory effects of beta2 adrenergic receptor agonists in experimental acute lung injury. Faseb J 2012, 26:2137-2144.
16. Grailer J.J., Haggadone M.D., Sarma J.V., Zetoune F.S., Ward P.A. Induction of M2 regulatory macrophages through the beta2-adrenergic receptor with protection during endotoxemia and acute lung injury. J Innate Immun 2014, 6:607-618.
17. Spengler R.N., Chensue S.W., Giacherio D.A., Blenk N., Kunkel S.L. Endogenous norepinephrine regulates tumor necrosis factor-alpha production from macrophages in vitro. J Immunol 1994, 152:3024-3031.
18. Grisanti L.A., Woster A.P., Dahlman J., Sauter E.R., Combs C.K., Porter J.E. Alpha1-adrenergic receptors positively regulate Toll-like receptor cytokine production from human monocytes and macrophages. J Pharmacol Exp Ther 2011, 338:648-657.
19. Rosas-Ballina M., Olofsson P.S., Ochani M., Valdés-Ferrer S.I., Levine Y.A., Reardon C., et al. Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science 2011, 334:98-101.
20. Gaskill P.J., Yano H.H., Kalpana G.V., Javitch J.A., Berman J.W. Dopamine receptor activation increases HIV entry into primary human macrophages. PLoS One 2014, 9.
21. Gaskill P.J., Calderon T.M., Luers A.J., Eugenin E.A., Javitch J.A., Berman J.W. Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse. Am J Pathol 2009, 175:1148-1159.
22. Czub S., Koutsilieri E., Sopper S., Czub M., Stahl-Hennig C., Muller J.G., et al. Enhancement of central nervous system pathology in early simian immunodeficiency virus infection by dopaminergic drugs. Acta Neuropathol 2001, 101:85-91.
23. Sedowofia K., Barclay C., Quaba A., Smith A., Stephen R., Thomson M., et al. The systemic stress response to thermal injury in children. Clin Endocrinol 1998, 49:335-341.
24. Sivamani R.K., Pullar C.E., Manabat-Hidalgo C.G., Rocke D.M., Carlsen R.C., Greenhalgh D.G., et al. Stress-mediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for beta blockers. PLoS Med 2009, 6:e1000012.
25. Romana-Souza B., Nascimento A.P., Brum P.C., Monte-Alto-Costa A. Deletion of the alpha2A/alpha2C-adrenoceptors accelerates cutaneous wound healing in mice. Int J Exp Pathol 2014, 95:330-341.
26. Kim M.H., Gorouhi F., Ramirez S., Granick J.L., Byrne B.A., Soulika A.M., et al. Catecholamine stress alters neutrophil trafficking and impairs wound healing by beta2-adrenergic receptor-mediated upregulation of IL-6. J Invest Dermatol 2014, 134:809-817.
27. Davis D., Carson M. An Introduction to CNS-resident microglia: definitions, assays, and functional roles in health and disease. Neural-immune interactions in brain function and alcohol related disorders 2013, 3-29. Springer, US. C. Cui, L. Grandison, A. Noronha (Eds.).
28. Carson M.J., Crane J., Xie A.X. Modeling CNS microglia: the quest to identify predictive models. Drug Discov Today Dis Models 2008, 5:19-25.
29. Gyoneva S., Shapiro L., Lazo C., Garnier-Amblard E., Smith Y., Miller G.W., et al. Adenosine A2A receptor antagonism reverses inflammation-induced impairment of microglial process extension in a model of Parkinson's disease. Neurobiol Dis 2014, 67:191-202.
30. Pannell M., Meier M.A., Szulzewsky F., Matyash V., Endres M., Kronenberg G., et al. The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease. Brain Struct Funct 2014, 19:19.
31. Gyoneva S., Traynelis S.F. Norepinephrine modulates the motility of resting and activated microglia via different adrenergic receptors. J Biol Chem 2013, 288:15291-15302.
32. Nguyen K.D., Qiu Y., Cui X., Goh Y.P., Mwangi J., David T., et al. Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature 2011, 480:104-108.
33. Qiu Y., Nguyen K.D., Odegaard J.I., Cui X., Tian X., Locksley R.M., et al. Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat. Cell 2014, 157:1292-1308.
34. Ouchi N., Parker J.L., Lugus J.J., Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol 2011, 11:85-97.
35. Abella V., Scotece M., Conde J., López V., Pez V., Nica, et al. Adipokines, metabolic syndrome and rheumatic diseases. J Immunol Res 2014, 2014:14.
36. Deng Y., Scherer P.E. Adipokines as novel biomarkers and regulators of the metabolic syndrome. Ann N Y Acad Sci 2010, 10.
37. Tilg H., Moschen A.R. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 2006, 6:772-783.
38. Navab M., Reddy S.T., Van Lenten B.J., Fogelman A.M. HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol 2011, 8:222-232.
39. Lu M., Gursky O. Aggregation and fusion of low-density lipoproteins and. Biomol Concepts 2013, 4:501-518.
40. Emanuel R., Sergin I., Bhattacharya S., Turner J.N., Epelman S., Settembre C., et al. Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae. Arterioscler Thromb Vasc Biol 2014, 34:1942-1952.
41. Yurdagul A., Green J., Albert P., McInnis M.C., Mazar A.P., Orr A.W. Alpha5beta1 integrin signaling mediates oxidized low-density lipoprotein-induced inflammation and early atherosclerosis. Arterioscler Thromb Vasc Biol 2014, 34:1362-1373.
42. Sherman C.B., Peterson S.J., Frishman W.H. Apolipoprotein A-I mimetic peptides: a potential new therapy for the prevention of atherosclerosis. Cardiol Rev 2010, 18:141-147.
43. Aluganti Narasimhulu C., Selvarajan K., Brown M., Parthasarathy S. Cationic peptides neutralize Ox-LDL, prevent its uptake by macrophages, and attenuate inflammatory response. Atherosclerosis 2014, 236:133-141.
44. Yang Y., Thyagarajan N., Coady B.M., Brown R.J. Cholesterol efflux from THP-1 macrophages is impaired by the fatty acid component from lipoprotein hydrolysis by lipoprotein lipase. Biochem Biophys Res Commun 2014, 451:632-636.
45. Qin X., Qiu C., Zhao L. Lysophosphatidylcholine perpetuates macrophage polarization toward classically activated phenotype in inflammation. Cell Immunol 2014, 289:185-190.
46. Park S.J., Lee K.P., Kang S., Lee J., Sato K., Chung H.Y., et al. Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4. Cell Signal 2014, 26:2249-2258.
47. Coleman D.L. Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 1973, 9:294-298.
48. Park HK, Ahima RS. Leptin signaling. F1000Prime Rep. 1000; 6: pp. 6-73.
49. Fernández-Riejos P., Najib S., Santos-Alvarez J., Mart, et al. Role of leptin in the activation of immune cells. Mediators Inflammation 2010, 2010.
50. Cava A.L., Matarese G. The weight of leptin in immunity. Nat Rev Immunol 2004, 4:371-379.
51. Dib L.H., Ortega M.T., Fleming S.D., Chapes S.K., Melgarejo T. Bone marrow leptin signaling mediates obesity-associated adipose tissue inflammation in male mice. Endocrinology 2014, 155:40-46.
52. Jitprasertwong P., Jaedicke K.M., Nile C.J., Preshaw P.M., Taylor J.J. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1. Cytokine 2014, 65:222-230.
53. Liu M.J., Bao S., Bolin E.R., Burris D.L., Xu X., Sun Q., et al. Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet. J Nutr 2013, 143:1036-1045.
54. Amarilyo G., Iikuni N., Liu A., Matarese G., La Cava A. Leptin enhances availability of apoptotic cell-derived self-antigen in systemic lupus erythematosus. PLoS One 2014, 9.
55. Luan B., Goodarzi M.O., Phillips N.G., Guo X., Chen Y.D., Yao J., et al. Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4. Cell Metab 2014, 19:1058-1065.
56. Abu-Farha M., Tiss A., Abubaker J., Khadir A., Al-Ghimlas F., Al-Khairi I., et al. Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity. PLoS One 2013, 8:e75342.
57. Nedvidkova J., Smitka K., Kopsky V., Hainer V. Adiponectin, an adipocyte-derived protein. Physiol Res 2005, 54:133-140.
58. Wolf A.M., Wolf D., Rumpold H., Enrich B., Tilg H. Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes. Biochem Biophys Res Commun 2004, 323:630-635.
59. Yamaguchi N., Argueta J.G., Masuhiro Y., Kagishita M., Nonaka K., Saito T., et al. Adiponectin inhibits Toll-like receptor family-induced signaling. FEBS Lett 2005, 579:6821-6826.
60. Yokota T., Oritani K., Takahashi I., Ishikawa J., Matsuyama A., Ouchi N., et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000, 96:1723-1732.
61. Hulsmans M., Geeraert B., Arnould T., Tsatsanis C., Holvoet P. PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression. PLoS One 2013, 8:e62253.
62. Wang M., Wang D., Zhang Y., Wang X., Liu Y., Xia M. Adiponectin increases macrophages cholesterol efflux and suppresses foam cell formation in patients with type 2 diabetes mellitus. Atherosclerosis 2013, 229:62-70.
63. Mandal P., Roychowdhury S., Park P.H., Pratt B.T., Roger T., Nagy L.E. Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure. J Immunol 2010, 185:4928-4937.
64. Thakur V., Pritchard M.T., McMullen M.R., Nagy L.E. Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feeding. Am J Physiol Gastrointest Liver Physiol 2006, 290:12.
65. Mandal P., Pratt B.T., Barnes M., McMullen M.R., Nagy L.E. Molecular mechanism for adiponectin-dependent M2 macrophage polarization: link between the metabolic and innate immune activity of full-length adiponectin. J. Biol. Chem. 2011, 286:13460-13469.
66. van Stijn C.M.W., Kim J., Lusis A.J., Barish G.D., Tangirala R.K. Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response. FASEB J 2014.
67. Steppan C.M., Bailey S.T., Bhat S., Brown E.J., Banerjee R.R., Wright C.M., et al. The hormone resistin links obesity to diabetes. Nature 2001, 409:307-312.
68. Schwartz D.R., Lazar M.A. Human resistin: found in translation from mouse to man. Trends Endocrinol Metab: TEM 2011, 22:259-265.
69. Nair M.G., Guild K.J., Artis D. Novel effector molecules in type 2 inflammation: lessons drawn from helminth infection and allergy. J Immunol 2006, 177:1393-1399.
70. McTernan P.G., Kusminski C.M., Kumar S. Resistin. Curr Opin Lipidol 2006, 17:170-175.
71. Park H.K., Ahima R.S. Resistin in rodents and humans. Diabetes Metab J 2013, 37:404-414.
72. Hasegawa G., Ohta M., Ichida Y., Obayashi H., Shigeta M., Yamasaki M., et al. Increased serum resistin levels in patients with type 2 diabetes are not linked with markers of insulin resistance and adiposity. Acta Diabetol 2005, 42:104-109.
73. Cho Y., Lee S.E., Lee H.C., Hur J., Lee S., Youn S.W., et al. Adipokine resistin is a key player to modulate monocytes, endothelial cells, and smooth muscle cells, leading to progression of atherosclerosis in rabbit carotid artery. J Am Coll Cardiol 2011, 57:99-109.
74. Pirvulescu M.M., Gan A.M., Stan D., Simion V., Calin M., Butoi E., et al. Subendothelial resistin enhances monocyte transmigration in a co-culture of human endothelial and smooth muscle cells by mechanisms involving fractalkine, MCP-1 and activation of TLR4 and Gi/o proteins signaling. Int J Biochem Cell Biol 2014, 50:29-37.
75. Jang J.C., Chen G., Wang S.H., Barnes M.A., Chung J.I., Camberis M., et al. Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. PLoS Pathog 2015, 11.
76. Nair M.G., Du Y., Perrigoue J.G., Zaph C., Taylor J.J., Goldschmidt M., et al. Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung. J Exp Med 2009, 206:937-952.
77. Pesce J.T., Ramalingam T.R., Wilson M.S., Mentink-Kane M.M., Thompson R.W., Cheever A.W., et al. Retnla (Relmα/Fizz1) suppresses helminth-induced Th2-type immunity. PLoS Pathog 2009, 5:e1000393.
78. Nair M.G., Gallagher I.J., Taylor M.D., Loke Pn., Coulson P.S., Wilson R.A., et al. Chitinase and fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells. Infect Immun 2005, 73:385-394.
79. Cook P.C., Jones L.H., Jenkins S.J., Wynn T.A., Allen J.E., MacDonald A.S. Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo. Proc Natl Acad Sci USA 2012, 109:9977-9982.
80. Liu T., Yu H., Ullenbruch M., Jin H., Ito T., Wu Z., et al. The In Vivo fibrotic role of FIZZ1 in pulmonary fibrosis. PLoS One 2014, 9:e88362.
81. Lee M.-R., Shim D., Yoon J., Jang H.S., Oh S.-W., Suh S.H., et al. Retnla overexpression attenuates allergic inflammation of the airway. PLoS One 2014, 9:e112666.
82. Osborne L.C., Joyce K.L., Alenghat T., Sonnenberg G.F., Giacomin P.R., Du Y., et al. Resistin-like molecule alpha promotes pathogenic Th17 cell responses and bacterial-induced intestinal inflammation. J Immunol 2013, 190:2292-2300.
83. Munitz A., Waddell A., Seidu L., Cole E.T., Ahrens R., Hogan S.P., et al. Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis. J Allergy Clin Immunol 2008, 122:1200-1207.
84. Lee M.-R., Lim C-j, Lee Y.-H., Park J.-G., Sonn S.K., Lee M.-N., et al. The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice. Nat Commun 2014, 5.
85. Herbert D.R., Yang J.Q., Hogan S.P., Groschwitz K., Khodoun M., Munitz A., et al. Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection. J Exp Med 2009, 206:2947-2957.
86. Nair M.G., Guild K.J., Du Y., Zaph C., Yancopoulos G.D., Valenzuela D.M., et al. Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation. J Immunol 2008, 181:4709-4715.
87. Kushiyama A., Sakoda H., Oue N., Okubo M., Nakatsu Y., Ono H., et al. Resistin-like molecule beta is abundantly expressed in foam cells and is involved in atherosclerosis development. Arterioscler Thromb Vasc Biol 2013, 33:1986-1993.
88. Shojima N., Ogihara T., Inukai K., Fujishiro M., Sakoda H., Kushiyama A., et al. Serum concentrations of resistin-like molecules beta and gamma are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow. Diabetologia 2005, 48:984-992.
89. Murray Peter J., Allen Judith E., Biswas Subhra K., Fisher Edward A., Gilroy Derek W., Goerdt S., et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 2014, 41:14-20.