메뉴 건너뛰기




Volumn 134, Issue 3, 2014, Pages 809-817

Catecholamine stress alters neutrophil trafficking and impairs wound healing by β 2 -adrenergic receptor-mediated Upregulation of Il-6

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BETA 2 ADRENERGIC RECEPTOR; CATECHOLAMINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; SALBUTAMOL; STRESS HORMONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84894031801     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.415     Document Type: Article
Times cited : (98)

References (51)
  • 1
    • 34248997759 scopus 로고    scopus 로고
    • Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
    • Arnold L, Henry A, Poron F et al. (2007) Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J Exp Med 204:1057-699
    • (2007) J Exp Med , vol.204 , pp. 1057-1699
    • Arnold, L.1    Henry, A.2    Poron, F.3
  • 2
    • 3042687755 scopus 로고    scopus 로고
    • In vivo interleukin-6 protects neutrophils from apoptosis in osteomyelitis
    • Asensi V, Valle E, Meana A et al. (2004) In vivo interleukin-6 protects neutrophils from apoptosis in osteomyelitis. Infect Immun 72:3823-88
    • (2004) Infect Immun , vol.72 , pp. 3823-3888
    • Asensi, V.1    Valle, E.2    Meana, A.3
  • 3
    • 14644421602 scopus 로고    scopus 로고
    • The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors
    • Baker JG (2005) The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol 144:317-222
    • (2005) Br J Pharmacol , vol.144 , pp. 317-222
    • Baker, J.G.1
  • 4
    • 0037201295 scopus 로고    scopus 로고
    • Immunomodulatory effects of vasoactive catecholamines
    • Bergmann M, Sautner T (2002) Immunomodulatory effects of vasoactive catecholamines. Wien Klin Wochenschr 114:752-611
    • (2002) Wien Klin Wochenschr , vol.114 , pp. 752-611
    • Bergmann, M.1    Sautner, T.2
  • 5
    • 0035160579 scopus 로고    scopus 로고
    • The effects of restraint stress on the neuropathogenesis of Theiler's virus infection: I
    • Campbell T, Meagher MW, Sieve A et al. (2001) The effects of restraint stress on the neuropathogenesis of Theiler's virus infection: I. Acute disease. Brain Behav Immun 15:235-544
    • (2001) Acute Disease. Brain Behav Immun , vol.15 , pp. 235-544
    • Campbell, T.1    Meagher, M.W.2    Sieve, A.3
  • 6
    • 78149467757 scopus 로고    scopus 로고
    • Association between plasma IL-6 response to acute stress and early-life adversity in healthy adults
    • Carpenter LL, Gawuga CE, Tyrka AR et al. (2010) Association between plasma IL-6 response to acute stress and early-life adversity in healthy adults. Neuropsychopharmacology 35:2617-233
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2617-2243
    • Carpenter, L.L.1    Gawuga, C.E.2    Tyrka, A.R.3
  • 7
    • 0033174282 scopus 로고    scopus 로고
    • Multiple epithelial cell-derived factors enhance neutrophil survival. Regulation by glucocorticoids and tumor necrosis factor-alpha
    • Daffern PJ, Jagels MA, Hugli TE (1999) Multiple epithelial cell-derived factors enhance neutrophil survival. Regulation by glucocorticoids and tumor necrosis factor-alpha. Am J Respir Cell Mol Biol 21:259-677
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 259-677
    • Daffern, P.J.1    Jagels, M.A.2    Hugli, T.E.3
  • 8
    • 2542478053 scopus 로고    scopus 로고
    • Wound healing: An overview of acute, fibrotic and delayed healing
    • Diegelmann RF, Evans MC (2004) Wound healing: an overview of acute, fibrotic and delayed healing. Front Biosci 9:283-99
    • (2004) Front Biosci , vol.9 , pp. 283-299
    • Diegelmann, R.F.1    Evans, M.C.2
  • 9
    • 0020507393 scopus 로고
    • Mechanism of plasma catecholamine increases during coronary artery bypass and valve procedures
    • Engelman RM, Haag B, Lemeshow S et al. (1983) Mechanism of plasma catecholamine increases during coronary artery bypass and valve procedures. J Thorac Cardiovasc Surg 86:608-155
    • (1983) J Thorac Cardiovasc Surg , vol.86 , pp. 608-155
    • Engelman, R.M.1    Haag, B.2    Lemeshow, S.3
  • 10
    • 0034662159 scopus 로고    scopus 로고
    • Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages
    • Faust N, Varas F, Kelly LM et al. (2000) Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood 96:719-266
    • (2000) Blood , vol.96 , pp. 719-266
    • Faust, N.1    Varas, F.2    Kelly, L.M.3
  • 11
    • 35148896954 scopus 로고    scopus 로고
    • Phagocyte-derived catecholamines enhance acute inflammatory injury
    • Flierl MA, Rittirsch D, Nadeau BA et al. (2007) Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature 449:721-55
    • (2007) Nature , vol.449 , pp. 721-755
    • Flierl, M.A.1    Rittirsch, D.2    Nadeau, B.A.3
  • 12
    • 1942518730 scopus 로고    scopus 로고
    • Epinephrine stimulates IL-6 expression in skeletal muscle and C2C12 myoblasts: Role of c-Jun NH2-terminal kinase and histone deacetylase activity
    • Frost RA, Nystrom GJ, Lang CH (2004) Epinephrine stimulates IL-6 expression in skeletal muscle and C2C12 myoblasts: role of c-Jun NH2-terminal kinase and histone deacetylase activity. Am J Physiol Endocrinol Metab 286:E809-177
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Frost, R.A.1    Nystrom, G.J.2    Lang, C.H.3
  • 13
    • 14944351958 scopus 로고    scopus 로고
    • Stress-induced immune dysfunction: Implications for health
    • Glaser R, Kiecolt-Glaser JK (2005) Stress-induced immune dysfunction: implications for health. Nat Rev Immunol 5:243-511
    • (2005) Nat Rev Immunol , vol.5 , pp. 243-511
    • Glaser, R.1    Kiecolt-Glaser, J.K.2
  • 14
    • 55049130410 scopus 로고    scopus 로고
    • The relationship between cytokine concentrations and wound healing in chronic venous ulceration
    • Gohel MS, Windhaber RA, Tarlton JF et al. (2008) The relationship between cytokine concentrations and wound healing in chronic venous ulceration. J Vasc Surg 48:1272-77
    • (2008) J Vasc Surg , vol.48 , pp. 1272-1277
    • Gohel, M.S.1    Windhaber, R.A.2    Tarlton, J.F.3
  • 15
    • 57149104111 scopus 로고    scopus 로고
    • Immune dysregulation and chronic stress among older adults: A review
    • Gouin JP, Hantsoo L, Kiecolt-Glaser JK (2008) Immune dysregulation and chronic stress among older adults: a review. Neuroimmunomodulation 15:251-99
    • (2008) Neuroimmunomodulation , vol.15 , pp. 251-299
    • Gouin, J.P.1    Hantsoo, L.2    Kiecolt-Glaser, J.K.3
  • 16
    • 84873358810 scopus 로고    scopus 로고
    • Behavioral stress accelerates prostate cancer development in mice
    • Hassan S, Karpova Y, Baiz D et al. (2013) Behavioral stress accelerates prostate cancer development in mice. J Clin Invest 123:874-866
    • (2013) J Clin Invest , vol.123 , pp. 874-866
    • Hassan, S.1    Karpova, Y.2    Baiz, D.3
  • 17
    • 0030198562 scopus 로고    scopus 로고
    • Differential regulation of proinflammatory cytokines during wound healing in normal and glucocorticoid- treated mice
    • Hubner G, Brauchle M, Smola H et al. (1996) Differential regulation of proinflammatory cytokines during wound healing in normal and glucocorticoid- treated mice. Cytokine 8:548-566
    • (1996) Cytokine , vol.8 , pp. 548-566
    • Hubner, G.1    Brauchle, M.2    Smola, H.3
  • 18
    • 0030605375 scopus 로고    scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston. Adrenergic receptors-evolving concepts and clinical implications
    • Insel PA (1996) Seminars in medicine of the Beth Israel Hospital, Boston. Adrenergic receptors-evolving concepts and clinical implications. N Engl J Med 334:580-55
    • (1996) N Engl J Med , vol.334 , pp. 580-565
    • Insel, P.A.1
  • 19
    • 33745826273 scopus 로고    scopus 로고
    • Attenuated stress-induced catecholamine release in mice lacking the vasopressin V1b receptor
    • Itoh S, Yamada S, Mori T et al. (2006) Attenuated stress-induced catecholamine release in mice lacking the vasopressin V1b receptor. Am J Physiol Endocrinol Metab 291:E147-511
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Itoh, S.1    Yamada, S.2    Mori, T.3
  • 20
    • 79960569443 scopus 로고    scopus 로고
    • Long-term persistance of the pathophysiologic response to severe burn injury
    • Jeschke MG, Gauglitz GG, Kulp GA et al. (2011) Long-term persistance of the pathophysiologic response to severe burn injury. PLoS One 6:e212455
    • (2011) PLoS One , vol.6
    • Jeschke, M.G.1    Gauglitz, G.G.2    Kulp, G.A.3
  • 21
    • 26244440570 scopus 로고    scopus 로고
    • Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines
    • Johnson JD, Campisi J, Sharkey CM et al. (2005) Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines. Neuroscience 135:1295-3077
    • (2005) Neuroscience , vol.135 , pp. 1295-3077
    • Johnson, J.D.1    Campisi, J.2    Sharkey, C.M.3
  • 22
    • 0036919969 scopus 로고    scopus 로고
    • Regulated expression of alpha-1 adrenergic receptors in the immune system
    • Kavelaars A (2002) Regulated expression of alpha-1 adrenergic receptors in the immune system. Brain Behav Immun 16:799-8077
    • (2002) Brain Behav Immun , vol.16 , pp. 799-8077
    • Kavelaars, A.1
  • 23
    • 0035051508 scopus 로고    scopus 로고
    • Catecholamines play a role in the production of interleukin-6 and interleukin-1alpha in unburned skin after burn injury in mice
    • Kawakami M, He J, Sakamoto T et al. (2001) Catecholamines play a role in the production of interleukin-6 and interleukin-1alpha in unburned skin after burn injury in mice. Crit Care Med 29:796-8011
    • (2001) Crit Care Med , vol.29 , pp. 796-8011
    • Kawakami, M.1    He, J.2    Sakamoto, T.3
  • 24
    • 0028792468 scopus 로고
    • Slowing of wound healing by psychological stress
    • Kiecolt-Glaser JK, Marucha PT, Malarkey WB et al. (1995) Slowing of wound healing by psychological stress. Lancet 346:1194-66
    • (1995) Lancet , vol.346 , pp. 1194-1176
    • Kiecolt-Glaser, J.K.1    Marucha, P.T.2    Malarkey, W.B.3
  • 25
    • 0041305837 scopus 로고    scopus 로고
    • Chronic stress and age-related increases in the proinflammatory cytokine IL-6
    • Kiecolt-Glaser JK, Preacher KJ, MacCallum RC et al. (2003) Chronic stress and age-related increases in the proinflammatory cytokine IL-6. Proc Natl Acad Sci USA 100:9090-55
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9090-9065
    • Kiecolt-Glaser, J.K.1    Preacher, K.J.2    Maccallum, R.C.3
  • 26
    • 79953070128 scopus 로고    scopus 로고
    • Neutrophil survival and c-kit- progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution
    • Kim MH, Granick JL, Kwok C et al. (2011) Neutrophil survival and c-kit- progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood 117:3343-522
    • (2011) Blood , vol.117 , pp. 3343-3522
    • Kim, M.H.1    Granick, J.L.2    Kwok, C.3
  • 27
    • 45349108369 scopus 로고    scopus 로고
    • Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging
    • Kim MH, Liu W, Borjesson DL et al. (2008) Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol 128:1812-200
    • (2008) J Invest Dermatol , vol.128 , pp. 1812-1210
    • Kim, M.H.1    Liu, W.2    Borjesson, D.L.3
  • 28
    • 0035210457 scopus 로고    scopus 로고
    • Norepinephrine and beta 2-adrenergic receptor stimulation regulate CD4-T and B lymphocyte function in vitro and in vivo
    • Kohm AP, Sanders VM (2001) Norepinephrine and beta 2-adrenergic receptor stimulation regulate CD4-T and B lymphocyte function in vitro and in vivo. Pharmacol Rev 53:487-5255
    • (2001) Pharmacol Rev , vol.53 , pp. 487-5255
    • Kohm, A.P.1    Sanders, V.M.2
  • 29
    • 79952754786 scopus 로고    scopus 로고
    • Does inflammation have a role in the pathogenesis of venous ulcers? A critical review of the evidence
    • Liu YC, Margolis DJ, Isseroff RR (2011) Does inflammation have a role in the pathogenesis of venous ulcers? A critical review of the evidence. J Invest Dermatol 131:818-277
    • (2011) J Invest Dermatol , vol.131 , pp. 818-277
    • Liu, Y.C.1    Margolis, D.J.2    Isseroff, R.R.3
  • 30
    • 0036632615 scopus 로고    scopus 로고
    • Epinephrine as a mediator of pulmonary neutrophil sequestration
    • Morken JJ, Warren KU, Xie Y et al. (2002) Epinephrine as a mediator of pulmonary neutrophil sequestration. Shock 18:46-500
    • (2002) Shock , vol.18 , pp. 46-500
    • Morken, J.J.1    Warren, K.U.2    Xie, Y.3
  • 31
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8:958-699
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-699
    • Mosser, D.M.1    Edwards, J.P.2
  • 32
    • 36549033197 scopus 로고    scopus 로고
    • The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
    • Nahrendorf M, Swirski FK, Aikawa E et al. (2007) The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med 204:3037-477
    • (2007) J Exp Med , vol.204 , pp. 3037-3477
    • Nahrendorf, M.1    Swirski, F.K.2    Aikawa, E.3
  • 33
    • 0036658735 scopus 로고    scopus 로고
    • Differential regulation of spontaneous and immune complex-induced neutrophil apoptosis by proinflammatory cytokines. Role of oxidants, Bax and caspase-3
    • Ottonello L, Frumento G, Arduino N et al. (2002) Differential regulation of spontaneous and immune complex-induced neutrophil apoptosis by proinflammatory cytokines. Role of oxidants, Bax and caspase-3. J Leukocyte Biol 72:125-322
    • (2002) J Leukocyte Biol , vol.72 , pp. 125-322
    • Ottonello, L.1    Frumento, G.2    Arduino, N.3
  • 35
    • 63049106661 scopus 로고    scopus 로고
    • Inflammation and neuropeptides: The connection in diabetic wound healing
    • Pradhan L, Nabzdyk C, Andersen ND et al. (2009) Inflammation and neuropeptides: the connection in diabetic wound healing. Expert Rev Mol Med 11:e22
    • (2009) Expert Rev Mol Med , vol.11
    • Pradhan, L.1    Nabzdyk, C.2    Andersen, N.D.3
  • 36
    • 21544434047 scopus 로고    scopus 로고
    • Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stressinduced depressive reactions
    • Ridder S, Chourbaji S, Hellweg R et al. (2005) Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stressinduced depressive reactions. J Neurosci 25:6243-500
    • (2005) J Neurosci , vol.25 , pp. 6243-6500
    • Ridder, S.1    Chourbaji, S.2    Hellweg, R.3
  • 37
    • 58349114669 scopus 로고    scopus 로고
    • Beta2 adrenoreceptor blockade attenuates the hyperinflammatory response induced by traumatic injury
    • Rough J, Engdahl R, Opperman K et al. (2009) Beta2 adrenoreceptor blockade attenuates the hyperinflammatory response induced by traumatic injury. Surgery 145:235-422
    • (2009) Surgery , vol.145 , pp. 235-422
    • Rough, J.1    Engdahl, R.2    Opperman, K.3
  • 38
    • 0031783482 scopus 로고    scopus 로고
    • The systemic stress response to thermal injury in children
    • Sedowofia K, Barclay C, Quaba A et al. (1998) The systemic stress response to thermal injury in children. Clin Endocrinol 49:335-411
    • (1998) Clin Endocrinol , vol.49 , pp. 335-411
    • Sedowofia, K.1    Barclay, C.2    Quaba, A.3
  • 39
    • 59249102783 scopus 로고    scopus 로고
    • Stressmediated increases in systemic and local epinephrine impair skin wound healing: Potential new indication for beta blockers
    • Sivamani RK, Pullar CE, Manabat-Hidalgo CG et al. (2009) Stressmediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for beta blockers. PLoS Med 6: e122
    • (2009) PLoS Med , vol.6
    • Sivamani, R.K.1    Pullar, C.E.2    Manabat-Hidalgo, C.G.3
  • 40
    • 0041506933 scopus 로고    scopus 로고
    • Pharmacology and physiology of human adrenergic receptor polymorphisms
    • Small KM, McGraw DW, Liggett SB (2003) Pharmacology and physiology of human adrenergic receptor polymorphisms. Annu Rev Pharmacol Toxicol 43:381-4111
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 381-4111
    • Small, K.M.1    McGraw, D.W.2    Liggett, S.B.3
  • 41
    • 68349117545 scopus 로고    scopus 로고
    • Cytokine secretion in macrophages and other cells: Pathways and mediators
    • Stow JL, Low PC, Offenhauser C et al. (2009) Cytokine secretion in macrophages and other cells: pathways and mediators. Immunobiology 214:601-122
    • (2009) Immunobiology , vol.214 , pp. 601-122
    • Stow, J.L.1    Low, P.C.2    Offenhauser, C.3
  • 42
    • 0028543542 scopus 로고
    • Immobilization stress may increase plasma interleukin-6 via central and peripheral catecholamines
    • Takaki A, Huang QH, Somogyvari-Vigh A et al. (1994) Immobilization stress may increase plasma interleukin-6 via central and peripheral catecholamines. Neuroimmunomodulation 1:335-422
    • (1994) Neuroimmunomodulation , vol.1 , pp. 335-422
    • Takaki, A.1    Huang, Q.H.2    Somogyvari-Vigh, A.3
  • 43
    • 33845907698 scopus 로고    scopus 로고
    • Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms
    • Tan KS, Nackley AG, Satterfield K et al. (2007) Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. Cell Signal 19:251-600
    • (2007) Cell Signal , vol.19 , pp. 251-600
    • Tan, K.S.1    Nackley, A.G.2    Satterfield, K.3
  • 44
    • 84872190964 scopus 로고    scopus 로고
    • Restraint stress alters neutrophil and macrophage phenotypes during wound healing
    • Tymen SD, Rojas IG, Zhou X et al. (2013) Restraint stress alters neutrophil and macrophage phenotypes during wound healing. Brain Behav Immun 28:207-177
    • (2013) Brain Behav Immun , vol.28 , pp. 207-177
    • Tymen, S.D.1    Rojas, I.G.2    Zhou, X.3
  • 45
    • 0036279933 scopus 로고    scopus 로고
    • Stress: A risk factor for serious illness
    • Vanitallie TB (2002) Stress: a risk factor for serious illness. Metabolisml 51:40-55
    • (2002) Metabolisml , vol.51 , pp. 40-55
    • Vanitallie, T.B.1
  • 46
    • 23844530949 scopus 로고    scopus 로고
    • Stress as an endogenous adjuvant: Augmentation of the immunization phase of cell-mediated immunity
    • Viswanathan K, Daugherty C, Dhabhar FS (2005) Stress as an endogenous adjuvant: augmentation of the immunization phase of cell-mediated immunity. Int Immunol 17:1059-699
    • (2005) Int Immunol , vol.17 , pp. 1059-1699
    • Viswanathan, K.1    Daugherty, C.2    Dhabhar, F.S.3
  • 47
    • 45849146525 scopus 로고    scopus 로고
    • Contribution of the sympathetic hormone epinephrine to the sensitizing effect of ethanol on LPS-induced liver damage in mice
    • von Montfort C, Beier JI, Guo L et al. (2008) Contribution of the sympathetic hormone epinephrine to the sensitizing effect of ethanol on LPS-induced liver damage in mice. Am J Physiol Gastrointest Liver Physiol 294:G1227-344
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Von Montfort, C.1    Beier, J.I.2    Guo, L.3
  • 48
    • 68549104031 scopus 로고    scopus 로고
    • Psychological stress and wound healing in humans: A systematic review and meta-analysis
    • Walburn J, Vedhara K, Hankins M et al. (2009) Psychological stress and wound healing in humans: a systematic review and meta-analysis. J Psychosom Res 67:253-711
    • (2009) J Psychosom Res , vol.67 , pp. 253-711
    • Walburn, J.1    Vedhara, K.2    Hankins, M.3
  • 50
    • 79955780432 scopus 로고    scopus 로고
    • Beta-adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat
    • Wohleb ES, Hanke ML, Corona AW et al. (2011) Beta-adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat. J Neurosci 31:6277-888
    • (2011) J Neurosci , vol.31 , pp. 6277-6888
    • Wohleb, E.S.1    Hanke, M.L.2    Corona, A.W.3
  • 51
    • 84864650145 scopus 로고    scopus 로고
    • Epinephrine: A short- and longterm regulator of stress and development of illness: A potential new role for epinephrine in stress
    • Wong DL, Tai TC, Wong-Faull DC et al. (2012) Epinephrine: a short- and longterm regulator of stress and development of illness: a potential new role for epinephrine in stress. Cell Mol Neurobiol 32:737-488
    • (2012) Cell Mol Neurobiol , vol.32 , pp. 737-488
    • Wong, D.L.1    Tai, T.C.2    Wong-Faull, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.