메뉴 건너뛰기




Volumn 3, Issue 7, 2002, Pages 531-541

Specification of catecholaminergic and serotonergic neurons

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOLAMINE; NORADRENALIN; SEROTONIN;

EID: 0036634851     PISSN: 14710048     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrn871     Document Type: Review
Times cited : (298)

References (98)
  • 4
    • 0032966607 scopus 로고    scopus 로고
    • Specification of dopaminergic and serotonergic neurons in the vertebrate CNS
    • Hynes, M. & Rosenthal, A. Specification of dopaminergic and serotonergic neurons in the vertebrate CNS. Curr. Opin. Neurobiol. 9, 26-36 (1999).
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 26-36
    • Hynes, M.1    Rosenthal, A.2
  • 6
    • 0025358029 scopus 로고
    • Target regulation of neurotransmitter phenotype
    • Landis, S. C. Target regulation of neurotransmitter phenotype. Trends Neurosci. 13, 344-350 (1990).
    • (1990) Trends Neurosci. , vol.13 , pp. 344-350
    • Landis, S.C.1
  • 7
    • 0033004556 scopus 로고    scopus 로고
    • Cellular and molecular determinants of sympathetic neuron development
    • Francis, N. J. & Landis, S. C. Cellular and molecular determinants of sympathetic neuron development. Annu. Rev. Neurosci. 22, 541-566 (1999).
    • (1999) Annu. Rev. Neurosci. , vol.22 , pp. 541-566
    • Francis, N.J.1    Landis, S.C.2
  • 8
    • 0032870841 scopus 로고    scopus 로고
    • Development of the cholinergic neurotransmitter phenotype in postganglionic sympathetic neurons
    • Emsberger, U. & Rohrer, H. Development of the cholinergic neurotransmitter phenotype in postganglionic sympathetic neurons. Cell Tissue Res. 297, 339-361 (1999).
    • (1999) Cell Tissue Res. , vol.297 , pp. 339-361
    • Emsberger, U.1    Rohrer, H.2
  • 9
    • 0027420712 scopus 로고
    • Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
    • Guillemot, F. et al. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell 75, 463-476 (1993). This paper provides the first genetic evidence for the essential role of Mash1 in sympathetic-neuron development.
    • (1993) Cell , vol.75 , pp. 463-476
    • Guillemot, F.1
  • 10
    • 0029116203 scopus 로고
    • The expression of tyrosine hydroxylase and the transcription factors cPhox-2 and Cash-1: Evidence for distinct inductive steps in the differentiation of chick sympathetic precursor cells
    • Emsberger, U. et al. The expression of tyrosine hydroxylase and the transcription factors cPhox-2 and Cash-1: evidence for distinct inductive steps in the differentiation of chick sympathetic precursor cells. Mech. Dev. 52, 125-136 (1995).
    • (1995) Mech. Dev. , vol.52 , pp. 125-136
    • Emsberger, U.1
  • 11
    • 0028915319 scopus 로고
    • Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons
    • Groves, A. K. et al. Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons. Development 121, 887-901 (1995).
    • (1995) Development , vol.121 , pp. 887-901
    • Groves, A.K.1
  • 12
    • 0031910150 scopus 로고    scopus 로고
    • Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system
    • Hirsch, M. R., Tiveron, M.-C., Guillemot, F., Brunet, J.-F. & Goridis, C. Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development 125, 599-608 (1998). This paper, together with reference 9, provides genetic evidence for the essential role of Mash1 in peripheral and central NA differentiation, acting independently of Phox2b.
    • (1998) Development , vol.125 , pp. 599-608
    • Hirsch, M.R.1    Tiveron, M.-C.2    Guillemot, F.3    Brunet, J.-F.4    Goridis, C.5
  • 13
    • 0028984464 scopus 로고
    • Number of adrenergic and islet-1 immunoreactive cells is increased in avian trunk neural crest cell cultures in the presence of human recombinant osteogenic protein-1
    • Varley, J. E., Wehby, R. G., Rueger, D. C. & Maxwell, G. D. Number of adrenergic and islet-1 immunoreactive cells is increased in avian trunk neural crest cell cultures in the presence of human recombinant osteogenic protein-1. Dev. Dyn. 203, 434-447 (1995).
    • (1995) Dev. Dyn. , vol.203 , pp. 434-447
    • Varley, J.E.1    Wehby, R.G.2    Rueger, D.C.3    Maxwell, G.D.4
  • 14
    • 0031908025 scopus 로고    scopus 로고
    • MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity
    • Lo, L., Tiveron, M.-C. & Anderson, D. J. MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity. Development 125, 609-620 (1998).
    • (1998) Development , vol.125 , pp. 609-620
    • Lo, L.1    Tiveron, M.-C.2    Anderson, D.J.3
  • 15
    • 0030018314 scopus 로고    scopus 로고
    • Involvement of bone morphogenetic protein-4 and bone morphogenetic protein-7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons
    • Reissmann, E. et al. Involvement of bone morphogenetic protein-4 and bone morphogenetic protein-7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons. Development 122, 2079-2088 (1996).
    • (1996) Development , vol.122 , pp. 2079-2088
    • Reissmann, E.1
  • 16
    • 0029897371 scopus 로고    scopus 로고
    • Alternative neural crest cell fates are instructively promoted by TGFβ superfamily members
    • Shah, N.M., Groves, A. K. & Anderson, D. J. Alternative neural crest cell fates are instructively promoted by TGFβ superfamily members. Cell 85, 331-343 (1996).
    • (1996) Cell , vol.85 , pp. 331-343
    • Shah, N.M.1    Groves, A.K.2    Anderson, D.J.3
  • 17
    • 0030198545 scopus 로고    scopus 로고
    • BMP2 and BMP4, but not BMP6 increase the number of adrenergic cells which develop in quail trunk neural crest cultures
    • Varley, J. E. & Maxwell, G. D. BMP2 and BMP4, but not BMP6 increase the number of adrenergic cells which develop in quail trunk neural crest cultures. Exp. Neurol. 140, 84-94 (1996).
    • (1996) Exp. Neurol. , vol.140 , pp. 84-94
    • Varley, J.E.1    Maxwell, G.D.2
  • 18
    • 0032053905 scopus 로고    scopus 로고
    • Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures
    • Varley, J. E., McPherson, C. E., Zou, H., Niswander, L. & Maxwell, G. D. Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures. Dev. Biol. 196, 107-118 (1998).
    • (1998) Dev. Biol. , vol.196 , pp. 107-118
    • Varley, J.E.1    McPherson, C.E.2    Zou, H.3    Niswander, L.4    Maxwell, G.D.5
  • 19
    • 0033385505 scopus 로고    scopus 로고
    • Bone morphogenetic proteins are required in vivo for the generation of sympathetic neurons
    • Schneider, C., Wicht, H., Enderich, J., Wegner, M. & Rohrer, H. Bone morphogenetic proteins are required in vivo for the generation of sympathetic neurons. Neuron 24, 861-870 (1999). This paper provides in vivo evidence for the essential role of BMPs In the development of peripheral NA neurons.
    • (1999) Neuron , vol.24 , pp. 861-870
    • Schneider, C.1    Wicht, H.2    Enderich, J.3    Wegner, M.4    Rohrer, H.5
  • 20
    • 0029958253 scopus 로고    scopus 로고
    • The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system
    • Tiveron, M.-C., Hirsch, M.-R. & Brunet, J.-F. The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system. J. Neurosci. 16, 7649-7660 (1996).
    • (1996) J. Neurosci. , vol.16 , pp. 7649-7660
    • Tiveron, M.-C.1    Hirsch, M.-R.2    Brunet, J.-F.3
  • 21
    • 0030731439 scopus 로고    scopus 로고
    • Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis
    • Pattyn, A., Morin, X., Cremer, H., Goridis, C. & Brunet, J.-F. Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development 124, 4065-4075 (1997).
    • (1997) Development , vol.124 , pp. 4065-4075
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.-F.5
  • 22
    • 0033609337 scopus 로고    scopus 로고
    • The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
    • Pattyn, A., Morin, X., Cremer, H., Goridis, C. & Brunet, J.-F. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature 399, 366-370 (1999). This paper presents genetic evidence for the crucial role of Phox2b in the development of peripheral NA neurons.
    • (1999) Nature , vol.399 , pp. 366-370
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.-F.5
  • 23
    • 0032841987 scopus 로고    scopus 로고
    • The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons
    • Stanke, M. et al. The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons. Development 126, 4087-4094 (1999). This study, together with reference 32, makes use of GOF methods to show that Phox2a and Phox2b are sufficient to initiate sympathetic-neuron development.
    • (1999) Development , vol.126 , pp. 4087-4094
    • Stanke, M.1
  • 24
    • 0030936255 scopus 로고    scopus 로고
    • Defects in sensory and autonomie ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a
    • Morin, X. et al. Defects in sensory and autonomie ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Neuron 18, 411-423 (1997). This paper shows the dependence of LC development on Phox2a.
    • (1997) Neuron , vol.18 , pp. 411-423
    • Morin, X.1
  • 25
    • 0030828004 scopus 로고    scopus 로고
    • The homeodomain protein Arix interacts synergistically with cyclic AMP to regulate expression of neurotransmitter biosynthetic genes
    • Swanson, D.J., Zellmer, E. & Lewis, E. J. The homeodomain protein Arix interacts synergistically with cyclic AMP to regulate expression of neurotransmitter biosynthetic genes. J. Biol. Chem. 272, 27382-27392 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 27382-27392
    • Swanson, D.J.1    Zellmer, E.2    Lewis, E.J.3
  • 26
    • 0031752431 scopus 로고    scopus 로고
    • Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine β-hydroxylase gene
    • Yang, C. et al. Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine β-hydroxylase gene. J. Neurochem. 71, 1813-1826 (1998).
    • (1998) J. Neurochem. , vol.71 , pp. 1813-1826
    • Yang, C.1
  • 27
    • 0032531711 scopus 로고    scopus 로고
    • Noradrenergic-specific transcription of the dopamine β-hydroxylase gene requires synergy of multiple cis-acting elements including at least two Phox2a-binding sites
    • Kim, H. S., Seo, H., Yang, C., Brunet, J.-F. &. Kim, K. S. Noradrenergic-specific transcription of the dopamine β-hydroxylase gene requires synergy of multiple cis-acting elements including at least two Phox2a-binding sites. J. Neurosci. 18, 8247-8260 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 8247-8260
    • Kim, H.S.1    Seo, H.2    Yang, C.3    Brunet, J.-F.4    Kim, K.S.5
  • 28
    • 0033819080 scopus 로고    scopus 로고
    • Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine β-hydroxylase gene transcription
    • Adachi, M., Browne, D. & Lewis, E. J. Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine β-hydroxylase gene transcription. DNA Cell Biol. 19, 539-554 (2000).
    • (2000) DNA Cell Biol. , vol.19 , pp. 539-554
    • Adachi, M.1    Browne, D.2    Lewis, E.J.3
  • 29
    • 0034723275 scopus 로고    scopus 로고
    • The homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine β-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding protein
    • Swanson, D. J., Adachi, M. & Lewis, E. J. The homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine β-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding protein. J. Biol. Chem. 275, 2911-2923 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 2911-2923
    • Swanson, D.J.1    Adachi, M.2    Lewis, E.J.3
  • 30
    • 0036312375 scopus 로고    scopus 로고
    • A direct role of the homeodomain proteins, Phox2a/b, in noradrenaline neurotransmitter identity determination
    • Seo, H. et al. A direct role of the homeodomain proteins, Phox2a/b, in noradrenaline neurotransmitter identity determination. J. Neurochem. 80, 905-916 (2002).
    • (2002) J. Neurochem. , vol.80 , pp. 905-916
    • Seo, H.1
  • 31
    • 0029583123 scopus 로고
    • A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes
    • Zellmer, E. et al. A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes. J. Neurosci. 15, 8109-8120 (1995).
    • (1995) J. Neurosci. , vol.15 , pp. 8109-8120
    • Zellmer, E.1
  • 32
    • 0033119681 scopus 로고    scopus 로고
    • Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells
    • Lo, L., Morin, X., Brunet, J.-F. & Anderson, D.J. Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells. Neuron 22, 693-705 (1999). This paper makes use of GOF methods to show that Phox2 genes are sufficient to initiate sympathetic-neuron development. It also provides evidence that implicates cAMP signalling in this process.
    • (1999) Neuron , vol.22 , pp. 693-705
    • Lo, L.1    Morin, X.2    Brunet, J.-F.3    Anderson, D.J.4
  • 33
    • 0034053353 scopus 로고    scopus 로고
    • Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b
    • Pattyn, A., Hirsch, M.-R., Goridis, C. & Brunet, J.-F. Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b. Development 127, 1349-1358 (2000).
    • (2000) Development , vol.127 , pp. 1349-1358
    • Pattyn, A.1    Hirsch, M.-R.2    Goridis, C.3    Brunet, J.-F.4
  • 34
    • 0033230089 scopus 로고    scopus 로고
    • Expression of HAND gene products may be sufficient for the differentiation of avian neural crest-derived cells into catecholaminergic neurons in culture
    • Howard, M., Foster, D. N. & Cserjesi, P. Expression of HAND gene products may be sufficient for the differentiation of avian neural crest-derived cells into catecholaminergic neurons in culture. Dev. Biol. 215, 62-77 (1999).
    • (1999) Dev. Biol. , vol.215 , pp. 62-77
    • Howard, M.1    Foster, D.N.2    Cserjesi, P.3
  • 35
    • 0033792535 scopus 로고    scopus 로고
    • The transcription factor dHAND is a downstream effector of BMPs in sympathetic neuron specification
    • Howard, M.J., Stanke, M., Schneider, C., Wu, X. & Rohrer, H. The transcription factor dHAND is a downstream effector of BMPs in sympathetic neuron specification. Development 127, 4073-4081 (2000). This study makes use of GOF methods to show the involvement of dHand in the development of sympathetic neurons.
    • (2000) Development , vol.127 , pp. 4073-4081
    • Howard, M.J.1    Stanke, M.2    Schneider, C.3    Wu, X.4    Rohrer, H.5
  • 37
    • 0030903857 scopus 로고    scopus 로고
    • Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
    • Srivastava, D. et al. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nature Genet. 16, 154-160 (1997).
    • (1997) Nature Genet. , vol.16 , pp. 154-160
    • Srivastava, D.1
  • 38
    • 0034096902 scopus 로고    scopus 로고
    • Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system
    • Lim, K. C. et al. Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. Nature Genet. 25, 209-212 (2000). This paper provides genetic evidence for a role of Gata3 in NA differentiation of the sympathetic lineage, but not in generic neuronal differentiation.
    • (2000) Nature Genet. , vol.25 , pp. 209-212
    • Lim, K.C.1
  • 39
    • 0026433037 scopus 로고
    • Expression cloning of a cocaine- And antidepressant-sensitive human noradrenaline transporter
    • Pacholczyk, T., Blakely, R. D. & Amara, S. G. Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter. Nature 350, 350-354 (1991).
    • (1991) Nature , vol.350 , pp. 350-354
    • Pacholczyk, T.1    Blakely, R.D.2    Amara, S.G.3
  • 40
    • 0022411868 scopus 로고
    • Non-neuronal cells from chick sympathetic and dorsal root sensory ganglia express catecholamine uptake and receptors for nerve growth factor during development
    • Rohrer, H. Non-neuronal cells from chick sympathetic and dorsal root sensory ganglia express catecholamine uptake and receptors for nerve growth factor during development. Dev. Biol. 111, 95-107 (1985).
    • (1985) Dev. Biol. , vol.111 , pp. 95-107
    • Rohrer, H.1
  • 41
    • 0033525881 scopus 로고    scopus 로고
    • A previously undescribed intron and extensive 5′ upstream sequence, but not Phox2a-mediated transactivation, are necessary for high level cell type-specific expression of the human norepinephrine transporter gene
    • Kim, C. H., Kim, H. S., Cubells, J. F. & Kim, K. S. A previously undescribed intron and extensive 5′ upstream sequence, but not Phox2a-mediated transactivation, are necessary for high level cell type-specific expression of the human norepinephrine transporter gene. J. Biol. Chem. 274, 6507-6518 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 6507-6518
    • Kim, C.H.1    Kim, H.S.2    Cubells, J.F.3    Kim, K.S.4
  • 42
    • 0015775446 scopus 로고
    • Time of origin of neurons in the brain stem of the mouse
    • Taber Pierce, E. Time of origin of neurons in the brain stem of the mouse. Prog. Brain Res. 40, 53-65 (1973).
    • (1973) Prog. Brain Res. , vol.40 , pp. 53-65
    • Taber Pierce, E.1
  • 43
    • 0024562741 scopus 로고
    • Two types of locus coeruleus neurons born on different embryonic days in the mouse
    • Steindler, D. A. & Trosko, B. K. Two types of locus coeruleus neurons born on different embryonic days in the mouse. Anat. Embryol. (Berl.) 179, 423-434 (1989).
    • (1989) Anat. Embryol. (Berl.) , vol.179 , pp. 423-434
    • Steindler, D.A.1    Trosko, B.K.2
  • 44
    • 0034034865 scopus 로고    scopus 로고
    • Specification of the central noradrenergic phenotype by the homeobox gene Phox2b
    • Pattyn, A, Goridis, C. & Brunet, J.-F. Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. Mol. Cell. Neurosci. 15, 235-243 (2000). This paper provides evidence for the essential role of Phox2b in LC development, acting downstream of Phox2a.
    • (2000) Mol. Cell. Neurosci. , vol.15 , pp. 235-243
    • Pattyn, A.1    Goridis, C.2    Brunet, J.-F.3
  • 45
    • 0036336407 scopus 로고    scopus 로고
    • The specification of noradrenergic locus coeruleus neurons depends on bone morphogenetic proteins
    • Vogel-Höpker, A. & Rohrer, H. The specification of noradrenergic locus coeruleus neurons depends on bone morphogenetic proteins. Development 129, 933-991 (2002). This paper, together with reference 48, presents in vivo evidence for a role of BMPs in the development of central NA neurons.
    • (2002) Development , vol.129 , pp. 933-991
    • Vogel-Höpker, A.1    Rohrer, H.2
  • 46
    • 0029162584 scopus 로고
    • Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
    • Liem, K. F. Jr, Tremml, G., Roelink, H. & Jessell, T. M. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82, 969-979 (1995).
    • (1995) Cell , vol.82 , pp. 969-979
    • Liem Jr., K.F.1    Tremml, G.2    Roelink, H.3    Jessell, T.M.4
  • 47
    • 0035213755 scopus 로고    scopus 로고
    • Neural patterning in the vertebrate embryo
    • Attmann, C. R. & Brivanlou, A. H. Neural patterning in the vertebrate embryo. Int. Rev. Cytol. 203, 447-482 (2001).
    • (2001) Int. Rev. Cytol. , vol.203 , pp. 447-482
    • Attmann, C.R.1    Brivanlou, A.H.2
  • 48
    • 0033231292 scopus 로고    scopus 로고
    • Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a
    • Guo, S. et al. Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a. Neuron 24, 555-566 (1999). This study provides genetic evidence in zebrafish for the involvement of BMPs, FGF8 and Phox2a in LC development.
    • (1999) Neuron , vol.24 , pp. 555-566
    • Guo, S.1
  • 49
    • 0033405806 scopus 로고    scopus 로고
    • Bmp activity establishes a gradient of positional information throughout the entire neural plate
    • Barth, K. A. et al. Bmp activity establishes a gradient of positional information throughout the entire neural plate. Development 126, 4977-4987 (1999).
    • (1999) Development , vol.126 , pp. 4977-4987
    • Barth, K.A.1
  • 50
    • 0035257203 scopus 로고    scopus 로고
    • Neural plate patterning: Upstream and downstream of the isthmic organizer
    • Wurst, W. & Bally-Cuif, L. Neural plate patterning: upstream and downstream of the isthmic organizer. Nature Rev. Neurosci. 2, 99-108 (2001).
    • (2001) Nature Rev. Neurosci. , vol.2 , pp. 99-108
    • Wurst, W.1    Bally-Cuif, L.2
  • 51
    • 0035477941 scopus 로고    scopus 로고
    • Formation of brainstem (nor)adrenergic centers and first-order relay visceral neurons is dependent on homeodomain protein Rnx/Tlx3
    • Qian, Y. et al. Formation of brainstem (nor)adrenergic centers and first-order relay visceral neurons is dependent on homeodomain protein Rnx/Tlx3. Genes Dev. 15, 2533-2545 (2001). This study shows that most central NA neurons depend on Rnx3, which acts independently of Phox2a.
    • (2001) Genes Dev. , vol.15 , pp. 2533-2545
    • Qian, Y.1
  • 52
    • 0032527602 scopus 로고    scopus 로고
    • Tlx-1 and Tlx-3 homeobox gene expression in cranial sensory ganglia and hindbrain of the chick embryo: Markers of patterned connectivity
    • Logan, C., Wingate, R. J. T., McKay, I. J. & Lumsden, A. Tlx-1 and Tlx-3 homeobox gene expression in cranial sensory ganglia and hindbrain of the chick embryo: markers of patterned connectivity. J. Neurosci. 18, 5389-5402 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 5389-5402
    • Logan, C.1    Wingate, R.J.T.2    McKay, I.J.3    Lumsden, A.4
  • 53
    • 0025001744 scopus 로고
    • Early appearance of tyrosine hydroxylase immunoreactive cells in the mesencephalon of mouse embryos
    • Di Porzio, U., Zuddas, A., Cosenza-Murphy, D. B. & Barker, J. L. Early appearance of tyrosine hydroxylase immunoreactive cells in the mesencephalon of mouse embryos. Int. J. Dev. Neurosci. 8, 523-532 (1990).
    • (1990) Int. J. Dev. Neurosci. , vol.8 , pp. 523-532
    • Di Porzio, U.1    Zuddas, A.2    Cosenza-Murphy, D.B.3    Barker, J.L.4
  • 54
    • 0029164902 scopus 로고
    • The role of the notochord and floor plate in inductive interactions
    • Placzek, M. The role of the notochord and floor plate in inductive interactions. Curr. Opin. Genet. Dev. 5, 499-506 (1995).
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 499-506
    • Placzek, M.1
  • 55
    • 0031679850 scopus 로고    scopus 로고
    • Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
    • Matise, M. P., Epstein, D. J., Park, H. L., Platt, K. A. & Joyner, A. L. Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development 125, 2759-2770 (1998).
    • (1998) Development , vol.125 , pp. 2759-2770
    • Matise, M.P.1    Epstein, D.J.2    Park, H.L.3    Platt, K.A.4    Joyner, A.L.5
  • 56
    • 0032577445 scopus 로고    scopus 로고
    • FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
    • Ye, W., Shimamura, K., Rubenstein, J. L., Hynes, M. A. & Rosenthal, A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93, 755-766 (1998). This paper presents evidence for the role of extrinsic signals in providing positional information in the specification of DA and 5-HT neurons.
    • (1998) Cell , vol.93 , pp. 755-766
    • Ye, W.1    Shimamura, K.2    Rubenstein, J.L.3    Hynes, M.A.4    Rosenthal, A.5
  • 57
    • 0034234546 scopus 로고    scopus 로고
    • Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice
    • Semina, E. V., Murray, J. C., Reiter, R., Hrstka, R. F. & Graw, J. Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice. Hum. Mol. Genet. 9, 1575-1585 (2000).
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1575-1585
    • Semina, E.V.1    Murray, J.C.2    Reiter, R.3    Hrstka, R.F.4    Graw, J.5
  • 58
    • 0035864962 scopus 로고    scopus 로고
    • A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice
    • Rieger, D. K., Reichenberger, E., McLean, W., Sidow, A. & Olsen, B. R. A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice. Genomics 72, 61-72 (2001).
    • (2001) Genomics , vol.72 , pp. 61-72
    • Rieger, D.K.1    Reichenberger, E.2    McLean, W.3    Sidow, A.4    Olsen, B.R.5
  • 59
    • 0030722332 scopus 로고    scopus 로고
    • A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons
    • Smidt, M. P. et al. A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc. Natl Acad. Sci. USA 94, 13305-13310 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13305-13310
    • Smidt, M.P.1
  • 60
    • 0033572907 scopus 로고    scopus 로고
    • Fate of mesencephalic AHD2-expressing dopamine progenitor cells in Nurr1 mutant mice
    • Wallen, A. et al. Fate of mesencephalic AHD2-expressing dopamine progenitor cells in Nurr1 mutant mice. Exp. Cell Res. 253, 737-746 (1999).
    • (1999) Exp. Cell Res. , vol.253 , pp. 737-746
    • Wallen, A.1
  • 61
    • 0034034739 scopus 로고    scopus 로고
    • A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b
    • This study provides genetic evidence for the essential role of Lmx1b in DA-neuron development
    • Smid, M. P. et al. A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nature Neurosci. 3, 337-341 (2000). This study provides genetic evidence for the essential role of Lmx1b in DA-neuron development.
    • (2000) Nature Neurosci. , vol.3 , pp. 337-341
    • Smid, M.P.1
  • 62
    • 0031002024 scopus 로고    scopus 로고
    • Dopamine neuron agenesis in Nurr-1 deficient mice
    • Zetterström, R. H. et al. Dopamine neuron agenesis in Nurr-1 deficient mice. Science 276, 248-250 (1997).
    • (1997) Science , vol.276 , pp. 248-250
    • Zetterström, R.H.1
  • 63
    • 0031805754 scopus 로고    scopus 로고
    • Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene
    • Castillo, S. O. et al. Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Mol. Cell. Neurosci. 11, 36-46 (1998).
    • (1998) Mol. Cell. Neurosci. , vol.11 , pp. 36-46
    • Castillo, S.O.1
  • 64
    • 0032584085 scopus 로고    scopus 로고
    • Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic fate dopaminergic precursor neurons
    • Together with references 62 and 63, this paper provides genetic evidence for a crucial role of Nurr1 in DA-neuron development
    • Saucedo-Cardenas, O. et al. Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic fate dopaminergic precursor neurons. Proc. Natl Acad. Sci. USA 95, 4013-4018 (1998). Together with references 62 and 63, this paper provides genetic evidence for a crucial role of Nurr1 in DA-neuron development.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 4013-4018
    • Saucedo-Cardenas, O.1
  • 65
    • 0032826958 scopus 로고    scopus 로고
    • Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice
    • Le, W.-D. et al. Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice. Exp. Neurol. 159, 451-458 (1999).
    • (1999) Exp. Neurol. , vol.159 , pp. 451-458
    • Le, W.-D.1
  • 66
    • 0034624242 scopus 로고    scopus 로고
    • Nigrostriatal innervation is preserved in Nurr1-null mice, although dopaminergic neuron precursors are arrested from terminal differentiation
    • Witta, J. et al. Nigrostriatal innervation is preserved in Nurr1-null mice, although dopaminergic neuron precursors are arrested from terminal differentiation. Brain Res. Mol. Brain Res. 84, 67-78 (2000).
    • (2000) Brain Res. Mol. Brain Res. , vol.84 , pp. 67-78
    • Witta, J.1
  • 67
    • 0029588435 scopus 로고
    • Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic
    • Zhou, Q.-Y. & Palmiter, R. D. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 83, 1197-1209 (1995).
    • (1995) Cell , vol.83 , pp. 1197-1209
    • Zhou, Q.-Y.1    Palmiter, R.D.2
  • 68
    • 0035091751 scopus 로고    scopus 로고
    • Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism
    • Sacchetti, P., Mitchell, T. R., Granneman, J. G. & Bannon, M. J. Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism. J. Neurochem. 76, 1565-1572 (2001).
    • (2001) J. Neurochem. , vol.76 , pp. 1565-1572
    • Sacchetti, P.1    Mitchell, T.R.2    Granneman, J.G.3    Bannon, M.J.4
  • 69
    • 0000190727 scopus 로고    scopus 로고
    • Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system
    • Zetterström, R. H., Williams, R., Perlmann, T. & Olson, L. Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system. Brain Res. Mol. Brain Res. 41, 111-120 (1998).
    • (1998) Brain Res. Mol. Brain Res. , vol.41 , pp. 111-120
    • Zetterström, R.H.1    Williams, R.2    Perlmann, T.3    Olson, L.4
  • 70
    • 0035684381 scopus 로고    scopus 로고
    • Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopaminergic neurons and in the brainstem
    • Wallen, A. et al. Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopaminergic neurons and in the brainstem. Mol. Cell. Neurosci. 18, 649-663 (2001).
    • (2001) Mol. Cell. Neurosci. , vol.18 , pp. 649-663
    • Wallen, A.1
  • 71
    • 0031747153 scopus 로고    scopus 로고
    • Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome
    • Chen, H. et al. Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome. Nature Genet. 19, 51-55 (1998).
    • (1998) Nature Genet. , vol.19 , pp. 51-55
    • Chen, H.1
  • 72
    • 0035341443 scopus 로고    scopus 로고
    • Fate of midbrain dopaminergic neurons controlled by the engrailed genes
    • Simon, H. H., Saueressig, H., Wurst, W., Goulding, M. D. & O'Leary, D. D. M. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. J. Neurosci. 21, 3126-3134 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 3126-3134
    • Simon, H.H.1    Saueressig, H.2    Wurst, W.3    Goulding, M.D.4    O'Leary, D.D.M.5
  • 73
    • 0028041321 scopus 로고
    • High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system
    • McCaffery, P. & Dräger, U. C. High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system. Proc. Natl Acad. Sci. USA 91, 7772-7776 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 7772-7776
    • McCaffery, P.1    Dräger, U.C.2
  • 74
    • 0032713404 scopus 로고    scopus 로고
    • Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways
    • Haselbeck, R. J., Hoffmann, I. & Duester, G. Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways. Dev. Genet. 25, 353-364 (1999).
    • (1999) Dev. Genet. , vol.25 , pp. 353-364
    • Haselbeck, R.J.1    Hoffmann, I.2    Duester, G.3
  • 75
    • 0028946634 scopus 로고
    • A novel pathway for vitamin A signaling mediated by RXR heterodimerisation with NGFI-B and NURR1
    • Perlmann, T. & Jansson, L. A novel pathway for vitamin A signaling mediated by RXR heterodimerisation with NGFI-B and NURR1. Genes Dev. 9, 769-782 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 769-782
    • Perlmann, T.1    Jansson, L.2
  • 76
    • 0035900751 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells
    • Castro, D. S. et al. Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells. J. Biol. Chem. 276, 43277-43284 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 43277-43284
    • Castro, D.S.1
  • 77
    • 0034676431 scopus 로고    scopus 로고
    • A regulator of transcriptional elongation controls vertebrate neuronal development
    • Guo, S. et al. A regulator of transcriptional elongation controls vertebrate neuronal development. Nature 408, 366-369 (2000).
    • (2000) Nature , vol.408 , pp. 366-369
    • Guo, S.1
  • 78
    • 0032874648 scopus 로고    scopus 로고
    • Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain
    • Sakurada, K., Ohshima-Sakurada, M., Palmer, T. D. & Gage, F. H. Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development 126, 4017-4026 (1999).
    • (1999) Development , vol.126 , pp. 4017-4026
    • Sakurada, K.1    Ohshima-Sakurada, M.2    Palmer, T.D.3    Gage, F.H.4
  • 79
    • 0034005734 scopus 로고    scopus 로고
    • A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter
    • Cazorla, P., Smidt, M. R. O'Malley, K. L. & Burbach, J. P. H. A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter. J. Neurochem. 74, 1829-1837 (2000).
    • (2000) J. Neurochem. , vol.74 , pp. 1829-1837
    • Cazorla, P.1    Smidt, M.R.2    O'Malley, K.L.3    Burbach, J.P.H.4
  • 80
    • 0035051188 scopus 로고    scopus 로고
    • Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity site
    • Lebel, M., Gauthier, Y., Moreau, A. & Drouin, J. Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity site. J. Neurochem. 77, 558-567 (2001).
    • (2001) J. Neurochem. , vol.77 , pp. 558-567
    • Lebel, M.1    Gauthier, Y.2    Moreau, A.3    Drouin, J.4
  • 81
    • 0034044317 scopus 로고    scopus 로고
    • Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
    • Lee, S. H., Lumelsky, N., Studer, L., Auerbach, J. M. & McKay, R. D. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nature Biotechnol. 18, 675-679 (2000).
    • (2000) Nature Biotechnol. , vol.18 , pp. 675-679
    • Lee, S.H.1    Lumelsky, N.2    Studer, L.3    Auerbach, J.M.4    McKay, R.D.5
  • 82
    • 0033638174 scopus 로고    scopus 로고
    • Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity
    • Kawasaki, H. et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28, 31-40 (2000).
    • (2000) Neuron , vol.28 , pp. 31-40
    • Kawasaki, H.1
  • 83
    • 0032980340 scopus 로고    scopus 로고
    • Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes
    • Wagner, J. et al. Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nature Biotechnol. 17, 653-659 (1999).
    • (1999) Nature Biotechnol. , vol.17 , pp. 653-659
    • Wagner, J.1
  • 84
    • 0033560895 scopus 로고    scopus 로고
    • Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
    • Briscoe, J. et al. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature 398, 622-627 (1999). This paper shows that the correct development of 5-HT neurons depends on Nkx2.2.
    • (1999) Nature , vol.398 , pp. 622-627
    • Briscoe, J.1
  • 85
    • 0033492916 scopus 로고    scopus 로고
    • The ETS domain factor Pet-1 is an early and precise marker of central serotoninergic neurons and interacts with a conserved element in serotonergic genes
    • Hendricks, T., Francis, N., Fyodorov, D. & Deneris, E. S. The ETS domain factor Pet-1 is an early and precise marker of central serotoninergic neurons and interacts with a conserved element in serotonergic genes. J. Neurosci. 19, 10348-10356 (1999).
    • (1999) J. Neurosci. , vol.19 , pp. 10348-10356
    • Hendricks, T.1    Francis, N.2    Fyodorov, D.3    Deneris, E.S.4
  • 86
    • 0036934860 scopus 로고    scopus 로고
    • mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons
    • Pfaar, H. et al. mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons. Dev. Genes Evol. 212, 43-46 (2002).
    • (2002) Dev. Genes Evol. , vol.212 , pp. 43-46
    • Pfaar, H.1
  • 87
    • 0023813741 scopus 로고
    • Early development of serotonin-containing neurons and pathways as seen in preparations of the fetal rat brain
    • Aitken, A.R. & Törk, I. Early development of serotonin-containing neurons and pathways as seen in preparations of the fetal rat brain. J. Comp. Neurol. 274, 32-47 (1988).
    • (1988) J. Comp. Neurol. , vol.274 , pp. 32-47
    • Aitken, A.R.1    Törk, I.2
  • 88
    • 0034640087 scopus 로고    scopus 로고
    • A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
    • Briscoe, J., Pierani, A., Jessell, T. M. & Ericson, J. A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 101, 435-445 (2000).
    • (2000) Cell , vol.101 , pp. 435-445
    • Briscoe, J.1    Pierani, A.2    Jessell, T.M.3    Ericson, J.4
  • 90
    • 0033371597 scopus 로고    scopus 로고
    • The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4
    • Pata, I. et al. The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. Development 126, 5523-5531 (1999).
    • (1999) Development , vol.126 , pp. 5523-5531
    • Pata, I.1
  • 91
    • 0033563363 scopus 로고    scopus 로고
    • GATA3 is involved in the development of serotonergic neurons in the caudal raphe nuclei
    • Hikke van Doominck, J. et al. GATA3 is involved in the development of serotonergic neurons in the caudal raphe nuclei. J. Neurosci. 19, RC12 (1999). This paper provides genetic evidence for a role of Gata3 in the differentiation of 5-HT neurons.
    • (1999) J. Neurosci. , vol.19
    • Van Hikke Doominck, J.1
  • 92
    • 0032583187 scopus 로고    scopus 로고
    • Transient developmental expression of monoamine transporters in the rodent forebrain
    • Lebrand, C. et al. Transient developmental expression of monoamine transporters in the rodent forebrain. J. Comp. Neurol. 401, 506-524 (1998).
    • (1998) J. Comp. Neurol. , vol.401 , pp. 506-524
    • Lebrand, C.1
  • 93
    • 0032509799 scopus 로고    scopus 로고
    • Serotonin transporter messenger RNA in the developing rat brain: Early expression in serotonergic neurons and transient expression in non-serotonergic neurons
    • Hansson, S. R., Mezey, E. & Hofman, B. J. Serotonin transporter messenger RNA in the developing rat brain: early expression in serotonergic neurons and transient expression in non-serotonergic neurons. Neuroscience 83, 1185-1201 (1998).
    • (1998) Neuroscience , vol.83 , pp. 1185-1201
    • Hansson, S.R.1    Mezey, E.2    Hofman, B.J.3
  • 94
    • 0035855787 scopus 로고    scopus 로고
    • The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2
    • Zhou, Q., Choi, G. & Anderson, D. J. The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. Neuron 31, 791-807 (2001).
    • (2001) Neuron , vol.31 , pp. 791-807
    • Zhou, Q.1    Choi, G.2    Anderson, D.J.3
  • 95
    • 0034303585 scopus 로고    scopus 로고
    • Neuronal specification in the spinal cord: Inductive signals and transcriptional codes
    • Jessell, T. M. Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nature Rev. Genet. 1, 20-29 (2000).
    • (2000) Nature Rev. Genet. , vol.1 , pp. 20-29
    • Jessell, T.M.1
  • 96
    • 0035929332 scopus 로고    scopus 로고
    • Cracking the transcriptional code for cell specification in the neural tube
    • Marquardt, T. & Pfaff, S. L. Cracking the transcriptional code for cell specification in the neural tube. Cell 106, 651-654 (2001).
    • (2001) Cell , vol.106 , pp. 651-654
    • Marquardt, T.1    Pfaff, S.L.2
  • 97
    • 0033006185 scopus 로고    scopus 로고
    • Transcriptional control of neurotransmitter phenotype
    • Goridis, C. & Brunet, J.-F. Transcriptional control of neurotransmitter phenotype. Curr. Opin. Neurobiol. 9, 47-53 (1999).
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 47-53
    • Goridis, C.1    Brunet, J.-F.2
  • 98


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.