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Volumn 206, Issue 4, 2009, Pages 937-952

Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung

Author keywords

[No Author keywords available]

Indexed keywords

BRUTON TYROSINE KINASE; CYTOKINE; RECOMBINANT CYTOKINE; RESISTIN LIKE MOLECULE ALPHA; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; LECTIN; MANNOSE BINDING LECTIN; MANNOSE RECEPTOR; RETNLA PROTEIN, MOUSE; SIGNAL PEPTIDE;

EID: 65549084867     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20082048     Document Type: Article
Times cited : (227)

References (65)
  • 2
    • 38549158099 scopus 로고    scopus 로고
    • Phagocytosis and comparative innate immunity: Learning on the fly
    • Stuart, L.M., and R.A. Ezekowitz. 2008. Phagocytosis and comparative innate immunity: learning on the fly. Nat. Rev. Immunol. 8:131-141.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 131-141
    • Stuart, L.M.1    Ezekowitz, R.A.2
  • 3
    • 17844386319 scopus 로고    scopus 로고
    • IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation
    • Lawrence, T., M. Bebien, G.Y. Liu, V. Nizet, and M. Karin. 2005. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature. 434:1138-1143.
    • (2005) Nature , vol.434 , pp. 1138-1143
    • Lawrence, T.1    Bebien, M.2    Liu, G.Y.3    Nizet, V.4    Karin, M.5
  • 4
    • 33751549013 scopus 로고    scopus 로고
    • Suppression of experimental colitis by intestinal mononuclear phagocytes
    • Qualls, J.E., A.M. Kaplan, N. van Rooijen, and D.A. Cohen. 2006. Suppression of experimental colitis by intestinal mononuclear phagocytes. J. Leukoc. Biol. 80:802-815.
    • (2006) J. Leukoc. Biol , vol.80 , pp. 802-815
    • Qualls, J.E.1    Kaplan, A.M.2    van Rooijen, N.3    Cohen, D.A.4
  • 5
    • 33845970192 scopus 로고    scopus 로고
    • Ly-6Chi monocytes dominate hypercholesterolemia- associated monocytosis and give rise to macrophages in atheromata
    • Swirski, F.K., P. Libby, E. Aikawa, P. Alcaide, F.W. Luscinskas, R. Weissleder, and M.J. Pittet. 2007. Ly-6Chi monocytes dominate hypercholesterolemia- associated monocytosis and give rise to macrophages in atheromata. J. Clin. Invest. 117:195-205.
    • (2007) J. Clin. Invest , vol.117 , pp. 195-205
    • Swirski, F.K.1    Libby, P.2    Aikawa, E.3    Alcaide, P.4    Luscinskas, F.W.5    Weissleder, R.6    Pittet, M.J.7
  • 7
    • 2942668626 scopus 로고    scopus 로고
    • Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation
    • Zhu, Z., T. Zheng, R.J. Homer, Y.K. Kim, N.Y. Chen, L. Cohn, Q. Hamid, and J.A. Elias. 2004. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science. 304:1678-1682.
    • (2004) Science , vol.304 , pp. 1678-1682
    • Zhu, Z.1    Zheng, T.2    Homer, R.J.3    Kim, Y.K.4    Chen, N.Y.5    Cohn, L.6    Hamid, Q.7    Elias, J.A.8
  • 10
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. 2003. Alternative activation of macrophages. Nat. Rev. Immunol. 3:23-35.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 11
    • 33746211119 scopus 로고    scopus 로고
    • Novel effector molecules in type 2 inflammation: Lessons drawn from helminth infection and allergy
    • Nair, M.G., K.J. Guild, and D. Artis. 2006. Novel effector molecules in type 2 inflammation: lessons drawn from helminth infection and allergy. J. Immunol. 177:1393-1399.
    • (2006) J. Immunol , vol.177 , pp. 1393-1399
    • Nair, M.G.1    Guild, K.J.2    Artis, D.3
  • 12
    • 0242421851 scopus 로고    scopus 로고
    • IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype
    • Loke, P., M.G. Nair, J. Parkinson, D. Guiliano, M. Blaxter, and J.E. Allen. 2002. IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype. BMC Immunol. 3:7.
    • (2002) BMC Immunol , vol.3 , pp. 7
    • Loke, P.1    Nair, M.G.2    Parkinson, J.3    Guiliano, D.4    Blaxter, M.5    Allen, J.E.6
  • 13
    • 0036553909 scopus 로고    scopus 로고
    • Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages
    • Raes, G., P. De Baetselier, W. Noel, A. Beschin, F. Brombacher, and G. Hassanzadeh Gh. 2002. Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J. Leukoc. Biol. 71:597-602.
    • (2002) J. Leukoc. Biol , vol.71 , pp. 597-602
    • Raes, G.1    De Baetselier, P.2    Noel, W.3    Beschin, A.4    Brombacher, F.5    Hassanzadeh Gh, G.6
  • 15
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • Condeelis, J., and J.W. Pollard. 2006. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell. 124:263-266.
    • (2006) Cell , vol.124 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 18
    • 2442717844 scopus 로고    scopus 로고
    • Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology
    • Herbert, D.R., C. Holscher, M. Mohrs, B. Arendse, A. Schwegmann, M. Radwanska, M. Leeto, R. Kirsch, P. Hall, H. Mossmann, et al. 2004. Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity. 20:623-635.
    • (2004) Immunity , vol.20 , pp. 623-635
    • Herbert, D.R.1    Holscher, C.2    Mohrs, M.3    Arendse, B.4    Schwegmann, A.5    Radwanska, M.6    Leeto, M.7    Kirsch, R.8    Hall, P.9    Mossmann, H.10
  • 19
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • Wynn, T.A. 2004. Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat. Rev. Immunol. 4:583-594.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 583-594
    • Wynn, T.A.1
  • 20
    • 35748964164 scopus 로고    scopus 로고
    • Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection
    • Loke, P., I. Gallagher, M.G. Nair, X. Zang, F. Brombacher, M. Mohrs, J.P. Allison, and J.E. Allen. 2007. Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection. J. Immunol. 179:3926-3936.
    • (2007) J. Immunol , vol.179 , pp. 3926-3936
    • Loke, P.1    Gallagher, I.2    Nair, M.G.3    Zang, X.4    Brombacher, F.5    Mohrs, M.6    Allison, J.P.7    Allen, J.E.8
  • 24
    • 11144286421 scopus 로고    scopus 로고
    • Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells
    • Nair, M.G., I.J. Gallagher, M.D. Taylor, P. Loke, P.S. Coulson, R.A. Wilson, R.M. Maizels, and J.E. Allen. 2005. Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells. Infect. Immun. 73:385-394.
    • (2005) Infect. Immun , vol.73 , pp. 385-394
    • Nair, M.G.1    Gallagher, I.J.2    Taylor, M.D.3    Loke, P.4    Coulson, P.S.5    Wilson, R.A.6    Maizels, R.M.7    Allen, J.E.8
  • 26
    • 2442707674 scopus 로고    scopus 로고
    • Disulfide-dependent multimeric assembly of resistin family hormones
    • Patel, S.D., M.W. Rajala, L. Rossetti, P.E. Scherer, and L. Shapiro. 2004. Disulfide-dependent multimeric assembly of resistin family hormones. Science. 304:1154-1158.
    • (2004) Science , vol.304 , pp. 1154-1158
    • Patel, S.D.1    Rajala, M.W.2    Rossetti, L.3    Scherer, P.E.4    Shapiro, L.5
  • 27
    • 0141989767 scopus 로고    scopus 로고
    • Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and th2 responses in tissue repair
    • Sandler, N.G., M.M. Mentink-Kane, A.W. Cheever, and T.A. Wynn. 2003. Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and th2 responses in tissue repair. J. Immunol. 171:3655-3667.
    • (2003) J. Immunol , vol.171 , pp. 3655-3667
    • Sandler, N.G.1    Mentink-Kane, M.M.2    Cheever, A.W.3    Wynn, T.A.4
  • 29
    • 4344600287 scopus 로고    scopus 로고
    • Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: Role of IL-4/IL-13 and mediation via STAT-6
    • Liu, T., H. Jin, M. Ullenbruch, B. Hu, N. Hashimoto, B. Moore, A. McKenzie, N.W. Lukacs, and S.H. Phan. 2004. Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6. J. Immunol. 173:3425-3431.
    • (2004) J. Immunol , vol.173 , pp. 3425-3431
    • Liu, T.1    Jin, H.2    Ullenbruch, M.3    Hu, B.4    Hashimoto, N.5    Moore, B.6    McKenzie, A.7    Lukacs, N.W.8    Phan, S.H.9
  • 30
    • 17844392652 scopus 로고    scopus 로고
    • Resistin, an adipokine with potent proinflammatory properties
    • Bokarewa, M., I. Nagaev, L. Dahlberg, U. Smith, and A. Tarkowski. 2005. Resistin, an adipokine with potent proinflammatory properties. J. Immunol. 174:5789-5795.
    • (2005) J. Immunol , vol.174 , pp. 5789-5795
    • Bokarewa, M.1    Nagaev, I.2    Dahlberg, L.3    Smith, U.4    Tarkowski, A.5
  • 31
    • 15044351514 scopus 로고    scopus 로고
    • Upregulation of hypoxia-induced mitogenic factor in compensatory lung growth after pneumonectomy
    • Li, D., L.G. Fernandez, J. Dodd-o, J. Langer, D. Wang, and V.E. Laubach. 2005. Upregulation of hypoxia-induced mitogenic factor in compensatory lung growth after pneumonectomy. Am. J. Respir. Cell Mol. Biol. 32:185-191.
    • (2005) Am. J. Respir. Cell Mol. Biol , vol.32 , pp. 185-191
    • Li, D.1    Fernandez, L.G.2    Dodd-o, J.3    Langer, J.4    Wang, D.5    Laubach, V.E.6
  • 32
    • 0038390235 scopus 로고    scopus 로고
    • FIZZ1/RELMalpha, a novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties
    • Teng, X., D. Li, H.C. Champion, and R.A. Johns. 2003. FIZZ1/RELMalpha, a novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties. Circ. Res. 92:1065-1067.
    • (2003) Circ. Res , vol.92 , pp. 1065-1067
    • Teng, X.1    Li, D.2    Champion, H.C.3    Johns, R.A.4
  • 34
    • 57149114576 scopus 로고    scopus 로고
    • Dynamics of lung macrophage activation in response to helminth infection
    • Siracusa, M.C., J.J. Reece, J.F. Urban Jr., and A.L. Scott. 2008. Dynamics of lung macrophage activation in response to helminth infection. J. Leukoc. Biol. 84:1422-1433.
    • (2008) J. Leukoc. Biol , vol.84 , pp. 1422-1433
    • Siracusa, M.C.1    Reece, J.J.2    Urban Jr., J.F.3    Scott, A.L.4
  • 35
    • 2942617055 scopus 로고    scopus 로고
    • A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma
    • van Rijt, L.S., H. Kuipers, N. Vos, D. Hijdra, H.C. Hoogsteden, and B.N. Lambrecht. 2004. A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma. J. Immunol. Methods. 288:111-121.
    • (2004) J. Immunol. Methods , vol.288 , pp. 111-121
    • van Rijt, L.S.1    Kuipers, H.2    Vos, N.3    Hijdra, D.4    Hoogsteden, H.C.5    Lambrecht, B.N.6
  • 36
    • 0021086786 scopus 로고
    • The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs
    • Hume, D.A., A.P. Robinson, G.G. MacPherson, and S. Gordon. 1983. The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs. J. Exp. Med. 158:1522-1536.
    • (1983) J. Exp. Med , vol.158 , pp. 1522-1536
    • Hume, D.A.1    Robinson, A.P.2    MacPherson, G.G.3    Gordon, S.4
  • 37
    • 0035576207 scopus 로고    scopus 로고
    • Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
    • Hesse, M., M. Modolell, A.C. La Flamme, M. Schito, J.M. Fuentes, A.W. Cheever, E.J. Pearce, and T.A. Wynn. 2001. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J. Immunol. 167:6533-6544.
    • (2001) J. Immunol , vol.167 , pp. 6533-6544
    • Hesse, M.1    Modolell, M.2    La Flamme, A.C.3    Schito, M.4    Fuentes, J.M.5    Cheever, A.W.6    Pearce, E.J.7    Wynn, T.A.8
  • 38
    • 58149286587 scopus 로고    scopus 로고
    • Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation
    • Nair, M.G., K.J. Guild, Y. Du, C. Zaph, G.D. Yancopoulos, D.M. Valenzuela, A. Murphy, S. Stevens, M. Karow, and D. Artis. 2008. Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation. J. Immunol. 181:4709-4715.
    • (2008) J. Immunol , vol.181 , pp. 4709-4715
    • Nair, M.G.1    Guild, K.J.2    Du, Y.3    Zaph, C.4    Yancopoulos, G.D.5    Valenzuela, D.M.6    Murphy, A.7    Stevens, S.8    Karow, M.9    Artis, D.10
  • 39
    • 0038302927 scopus 로고    scopus 로고
    • PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
    • Loke, P., and J.P. Allison. 2003. PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells. Proc. Natl. Acad. Sci. USA. 100:5336-5341.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5336-5341
    • Loke, P.1    Allison, J.P.2
  • 40
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
    • Stein, M., S. Keshav, N. Harris, and S. Gordon. 1992. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176:287-292.
    • (1992) J. Exp. Med , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 41
    • 34247565028 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase (BTK) is a binding partner for hypoxia induced mitogenic factor (HIMF/FIZZ1) and mediates myeloid cell chemotaxis
    • Su, Q., Y. Zhou, and R.A. Johns. 2007. Bruton's tyrosine kinase (BTK) is a binding partner for hypoxia induced mitogenic factor (HIMF/FIZZ1) and mediates myeloid cell chemotaxis. FASEB J. 21:1376-1382.
    • (2007) FASEB J , vol.21 , pp. 1376-1382
    • Su, Q.1    Zhou, Y.2    Johns, R.A.3
  • 43
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok, V.A., D.L. Bratton, A. Konowal, P.W. Freed, J.Y. Westcott, and P.M. Henson. 1998. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J. Clin. Invest. 101:890-898.
    • (1998) J. Clin. Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 45
    • 0024378214 scopus 로고
    • Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice
    • Thepen, T., N. Van Rooijen, and G. Kraal. 1989. Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice. J. Exp. Med. 170:499-509.
    • (1989) J. Exp. Med , vol.170 , pp. 499-509
    • Thepen, T.1    Van Rooijen, N.2    Kraal, G.3
  • 46
    • 0035337139 scopus 로고    scopus 로고
    • Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors
    • Gerber, J.S., and D.M. Mosser. 2001. Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors. J. Immunol. 166:6861-6868.
    • (2001) J. Immunol , vol.166 , pp. 6861-6868
    • Gerber, J.S.1    Mosser, D.M.2
  • 47
    • 33947622744 scopus 로고    scopus 로고
    • Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism
    • Smith, P., N.E. Mangan, C.M. Walsh, R.E. Fallon, A.N. McKenzie, N. van Rooijen, and P.G. Fallon. 2007. Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J. Immunol. 178:4557-4566.
    • (2007) J. Immunol , vol.178 , pp. 4557-4566
    • Smith, P.1    Mangan, N.E.2    Walsh, C.M.3    Fallon, R.E.4    McKenzie, A.N.5    van Rooijen, N.6    Fallon, P.G.7
  • 48
    • 33646884472 scopus 로고    scopus 로고
    • F4/80+ alternatively activated macrophages control CD4+ T cell hyporesponsiveness at sites peripheral to filarial infection
    • Taylor, M.D., A. Harris, M.G. Nair, R.M. Maizels, and J.E. Allen. 2006. F4/80+ alternatively activated macrophages control CD4+ T cell hyporesponsiveness at sites peripheral to filarial infection. J. Immunol. 176:6918-6927.
    • (2006) J. Immunol , vol.176 , pp. 6918-6927
    • Taylor, M.D.1    Harris, A.2    Nair, M.G.3    Maizels, R.M.4    Allen, J.E.5
  • 49
    • 49649111406 scopus 로고    scopus 로고
    • Airway epithelial cells modify immune responses by inducing an antiinflammatory microenvironment
    • Mayer, A.K., H. Bartz, F. Fey, L.M. Schmidt, and A.H. Dalpke. 2008. Airway epithelial cells modify immune responses by inducing an antiinflammatory microenvironment. Eur. J. Immunol. 38:1689-1699.
    • (2008) Eur. J. Immunol , vol.38 , pp. 1689-1699
    • Mayer, A.K.1    Bartz, H.2    Fey, F.3    Schmidt, L.M.4    Dalpke, A.H.5
  • 56
    • 33646424352 scopus 로고    scopus 로고
    • Upregulation of hypoxia-induced mitogenic factor in bacterial lipopolysaccharide-induced acute lung injury
    • Tong, Q., L. Zheng, Q. Kang, O.J. Dodd, J. Langer, B. Li, D. Wang, and D. Li. 2006. Upregulation of hypoxia-induced mitogenic factor in bacterial lipopolysaccharide-induced acute lung injury. FEBS Lett. 580:2207-2215.
    • (2006) FEBS Lett , vol.580 , pp. 2207-2215
    • Tong, Q.1    Zheng, L.2    Kang, Q.3    Dodd, O.J.4    Langer, J.5    Li, B.6    Wang, D.7    Li, D.8
  • 57
    • 33749183547 scopus 로고    scopus 로고
    • Hypoxiainduced mitogenic factor promotes vascular adhesion molecule-1 expression via the PI-3K/Akt-NF-kappaB signaling pathway
    • Tong, Q., L. Zheng, L. Lin, B. Li, D. Wang, and D. Li. 2006. Hypoxiainduced mitogenic factor promotes vascular adhesion molecule-1 expression via the PI-3K/Akt-NF-kappaB signaling pathway. Am. J. Respir. Cell Mol. Biol. 35:444-456.
    • (2006) Am. J. Respir. Cell Mol. Biol , vol.35 , pp. 444-456
    • Tong, Q.1    Zheng, L.2    Lin, L.3    Li, B.4    Wang, D.5    Li, D.6
  • 58
    • 33645576824 scopus 로고    scopus 로고
    • VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-kappaB signaling pathway
    • Tong, Q., L. Zheng, L. Lin, B. Li, D. Wang, C. Huang, and D. Li. 2006. VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-kappaB signaling pathway. Respir. Res. 7:37.
    • (2006) Respir. Res , vol.7 , pp. 37
    • Tong, Q.1    Zheng, L.2    Lin, L.3    Li, B.4    Wang, D.5    Huang, C.6    Li, D.7
  • 59
    • 33748087483 scopus 로고    scopus 로고
    • Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages
    • Reece, J.J., M.C. Siracusa, and A.L. Scott. 2006. Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages. Infect. Immun. 74:4970-4981.
    • (2006) Infect. Immun , vol.74 , pp. 4970-4981
    • Reece, J.J.1    Siracusa, M.C.2    Scott, A.L.3
  • 60
    • 1342292522 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase: Diverse roles in immune cell activation
    • Deane, J.A., and D.A. Fruman. 2004. Phosphoinositide 3-kinase: diverse roles in immune cell activation. Annu. Rev. Immunol. 22:563-598.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 563-598
    • Deane, J.A.1    Fruman, D.A.2
  • 61
    • 40549124306 scopus 로고    scopus 로고
    • Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5
    • Xiao, W., H. Hong, Y. Kawakami, C.A. Lowell, and T. Kawakami. 2008. Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5. J. Clin. Invest. 118:924-934.
    • (2008) J. Clin. Invest , vol.118 , pp. 924-934
    • Xiao, W.1    Hong, H.2    Kawakami, Y.3    Lowell, C.A.4    Kawakami, T.5
  • 63
    • 34249695187 scopus 로고    scopus 로고
    • Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes
    • Nagaev, I., M. Bokarewa, A. Tarkowski, and U. Smith. 2006. Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes. PLoS One. 1:e31.
    • (2006) PLoS One , vol.1
    • Nagaev, I.1    Bokarewa, M.2    Tarkowski, A.3    Smith, U.4


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