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Volumn 155, Issue 1, 2014, Pages 40-46

Bone marrow leptin signaling mediates obesity-Associated adipose tissue inflammation in male mice

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; C C CHEMOKINE RECEPTOR TYPE 2; CHEMOKINE; GALACTOSE; LEPTIN; MACROPHAGE GALACTOSE TYPE C TYPE LECTIN 1; UNCLASSIFIED DRUG;

EID: 84891404634     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1607     Document Type: Article
Times cited : (52)

References (45)
  • 2
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Invest. 2005;115:1111-1119.
    • (2005) J Clin Invest. , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 3
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: The link between insulin resistance, obesity and diabetes
    • Dandona P, Aljada A, Bandyopadhyay A. Inflammation: The link between insulin resistance, obesity and diabetes. Trends Immunol. 2004;25:4-7.
    • (2004) Trends Immunol. , vol.25 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 4
    • 33644856005 scopus 로고    scopus 로고
    • Obesity and the role of adipose tissue in inflammation and metabolism
    • Greenberg AS, Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr. 2006;83:461S-465S.
    • (2006) Am J Clin Nutr. , vol.83
    • Greenberg, A.S.1    Obin, M.S.2
  • 5
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
    • Tilg H, Moschen AR. Adipocytokines: Mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol. 2006;6: 772-783.
    • (2006) Nat Rev Immunol. , vol.6 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 7
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112:1821-1830.
    • (2003) J Clin Invest. , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 8
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest. 2007;117:175-184.
    • (2007) J Clin Invest. , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 9
    • 58149347227 scopus 로고    scopus 로고
    • Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
    • Lumeng CN, DelProposto JB, Westcott DJ, Saltiel AR. Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes. 2008;57:3239-3246.
    • (2008) Diabetes. , vol.57 , pp. 3239-3246
    • Lumeng, C.N.1    DelProposto, J.B.2    Westcott, D.J.3    Saltiel, A.R.4
  • 10
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res. 2005;46:2347-2355.
    • (2005) J Lipid Res. , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3
  • 11
    • 33847073149 scopus 로고    scopus 로고
    • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
    • Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes. 2007;56:16-23.
    • (2007) Diabetes. , vol.56 , pp. 16-23
    • Lumeng, C.N.1    Deyoung, S.M.2    Bodzin, J.L.3    Saltiel, A.R.4
  • 12
    • 73949125691 scopus 로고    scopus 로고
    • MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity
    • Westcott DJ, Delproposto JB, Geletka LM, et al. MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity. J Exp Med. 2009;206:3143-3156.
    • (2009) J Exp Med. , vol.206 , pp. 3143-3156
    • Westcott, D.J.1    Delproposto, J.B.2    Geletka, L.M.3
  • 13
    • 84877841706 scopus 로고    scopus 로고
    • Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice
    • Aouadi M, Tencerova M, Vangala P, et al. Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice. Proc Natl Acad Sci U S A. 2013;110:8278-8283.
    • (2013) Proc Natl Acad Sci U S A. , vol.110 , pp. 8278-8283
    • Aouadi, M.1    Tencerova, M.2    Vangala, P.3
  • 14
    • 2442618838 scopus 로고    scopus 로고
    • The weight of leptin in immunity
    • La Cava A, Matarese G. The weight of leptin in immunity. Nat Rev Immunol. 2004;4:371-379.
    • (2004) Nat Rev Immunol. , vol.4 , pp. 371-379
    • La Cava, A.1    Matarese, G.2
  • 15
    • 2442654859 scopus 로고
    • Identification and expression cloning of a leptin receptor OB-R
    • Tartaglia LA, Dembski M, Weng X, et al. Identification and expression cloning of a leptin receptor, OB-R. Cell. 1995;83:1263-1271.
    • (1995) Cell. , vol.83 , pp. 1263-1271
    • Tartaglia, L.A.1    Dembski, M.2    Weng, X.3
  • 16
    • 73649112416 scopus 로고    scopus 로고
    • Leptin: A critical regulator of CD4+ T-cell polarization in vitro and in vivo
    • Batra A, Okur B, Glauben R, et al. Leptin: A critical regulator of CD4+ T-cell polarization in vitro and in vivo. Endocrinology. 2010; 151:56-62.
    • (2010) Endocrinology. , vol.151 , pp. 56-62
    • Batra, A.1    Okur, B.2    Glauben, R.3
  • 17
    • 33744946045 scopus 로고    scopus 로고
    • Leptin receptor expression and signaling in lymphocytes: Kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice
    • Papathanassoglou E, El-Haschimi K, Li XC, Matarese G, Strom T, Mantzoros C. Leptin receptor expression and signaling in lymphocytes: Kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice. J Immunol. 2006;176: 7745-7752.
    • (2006) J Immunol. , vol.176 , pp. 7745-7752
    • Papathanassoglou, E.1    El-Haschimi, K.2    Li, X.C.3    Matarese, G.4    Strom, T.5    Mantzoros, C.6
  • 18
    • 0036854487 scopus 로고    scopus 로고
    • Leptin potentiates IFN-γ-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1
    • Raso GM, Pacilio M, Esposito E, Coppola A, Di Carlo R, Meli R. Leptin potentiates IFN-γ-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1. Br J Pharmacol. 2002;137:799-804.
    • (2002) Br J Pharmacol. , vol.137 , pp. 799-804
    • Raso, G.M.1    Pacilio, M.2    Esposito, E.3    Coppola, A.4    Di Carlo, R.5    Meli, R.6
  • 19
    • 18944364947 scopus 로고    scopus 로고
    • Leptin promotes differentiation and survival of human dendritic cells and licenses them for Th1 priming
    • Mattioli B, Straface E, Quaranta MG, Giordani L, Viora M. Leptin promotes differentiation and survival of human dendritic cells and licenses them for Th1 priming. J Immunol. 2005;174:6820-6828.
    • (2005) J Immunol. , vol.174 , pp. 6820-6828
    • Mattioli, B.1    Straface, E.2    Quaranta, M.G.3    Giordani, L.4    Viora, M.5
  • 20
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive- leptin concentrations in normal-weight and obese humans
    • Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive- leptin concentrations in normal-weight and obese humans. N Engl J Med. 1996;334:292-295.
    • (1996) N Engl J Med. , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3
  • 21
    • 39449103260 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo
    • Lim WS, Timmins JM, Seimon TA, et al. Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo. Circulation. 2008;117:940-951.
    • (2008) Circulation. , vol.117 , pp. 940-951
    • Lim, W.S.1    Timmins, J.M.2    Seimon, T.A.3
  • 22
    • 38949125499 scopus 로고    scopus 로고
    • Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice
    • Lee S, Muniyappa R, Yan X, et al. Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice. Am J Physiol Endocrinol Metab. 2008;294:E261-E270.
    • (2008) Am J Physiol Endocrinol Metab. , vol.294
    • Lee, S.1    Muniyappa, R.2    Yan, X.3
  • 23
    • 80052373417 scopus 로고    scopus 로고
    • Evaluation of macrophage plasticity in brown and white adipose tissue
    • Ortega MT, Xie L, Mora S, Chapes SK. Evaluation of macrophage plasticity in brown and white adipose tissue. Cell Immunol. 2011; 271:124-133.
    • (2011) Cell Immunol. , vol.271 , pp. 124-133
    • Ortega, M.T.1    Xie, L.2    Mora, S.3    Chapes, S.K.4
  • 24
    • 34547182426 scopus 로고    scopus 로고
    • Reduced adiposity in ob/ob mice following total body irradiation and bone marrow transplantation
    • Ablamunits V, Weisberg SP, Lemieux JE, Combs TP, Klebanov S. Reduced adiposity in ob/ob mice following total body irradiation and bone marrow transplantation. Obesity. 2007;15:1419-1429.
    • (2007) Obesity. , vol.15 , pp. 1419-1429
    • Ablamunits, V.1    Weisberg, S.P.2    Lemieux, J.E.3    Combs, T.P.4    Klebanov, S.5
  • 25
    • 58249111473 scopus 로고    scopus 로고
    • Adipose tissue sensitivity to radiation exposure
    • Poglio S, Galvani S, Bour S, et al. Adipose tissue sensitivity to radiation exposure. Am J Pathol. 2009;174:44-53.
    • (2009) Am J Pathol. , vol.174 , pp. 44-53
    • Poglio, S.1    Galvani, S.2    Bour, S.3
  • 26
    • 69449097633 scopus 로고    scopus 로고
    • The protein kinase IKKε regulates energy balance in obese mice
    • Chiang SH, Bazuine M, Lumeng CN, et al. The protein kinase IKKε regulates energy balance in obese mice. Cell. 2009;138:961-975.
    • (2009) Cell. , vol.138 , pp. 961-975
    • Chiang, S.H.1    Bazuine, M.2    Lumeng, C.N.3
  • 27
    • 44449110675 scopus 로고    scopus 로고
    • Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat
    • Davis JE, Gabler NK, Walker-Daniels J, Spurlock ME. Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity. 2008;16:1248-1255.
    • (2008) Obesity. , vol.16 , pp. 1248-1255
    • Davis, J.E.1    Gabler, N.K.2    Walker-Daniels, J.3    Spurlock, M.E.4
  • 28
    • 31044456529 scopus 로고    scopus 로고
    • CCR2 modulates inflammatory and metabolic effects of high-fat feeding
    • Weisberg SP, Hunter D, Huber R, et al. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest. 2006; 116:115-124.
    • (2006) J Clin Invest. , vol.116 , pp. 115-124
    • Weisberg, S.P.1    Hunter, D.2    Huber, R.3
  • 29
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • Kanda H, Tateya S, Tamori Y, et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest. 2006;116:1494-1505.
    • (2006) J Clin Invest. , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3
  • 30
    • 34147122535 scopus 로고    scopus 로고
    • Bone marrow-specificCap gene deletion protects against high-fat diet-induced insulin resistance
    • Lesniewski LA, Hosch SE, Neels JG, et al. Bone marrow-specificCap gene deletion protects against high-fat diet-induced insulin resistance. Nat Med. 2007;13:455-462.
    • (2007) Nat Med. , vol.13 , pp. 455-462
    • Lesniewski, L.A.1    Hosch, S.E.2    Neels, J.G.3
  • 31
    • 59149093623 scopus 로고    scopus 로고
    • Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program
    • Muruganandan S,RomanAA, Sinal CJ. Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program. Cell Mol Life Sci. 2009;66:236-253.
    • (2009) Cell Mol Life Sci. , vol.66 , pp. 236-253
    • Muruganandan, S.1    Roman, A.A.2    Sinal, C.J.3
  • 33
    • 78649972071 scopus 로고    scopus 로고
    • Generation of leptin receptor bone marrow chimeras: Recovery from irradiation, immune cellularity, cytokine expression, and metabolic parameters
    • Gove ME, Sherry CL, Pini M, Fantuzzi G. Generation of leptin receptor bone marrow chimeras: Recovery from irradiation, immune cellularity, cytokine expression, and metabolic parameters. Obesity. 2010;18:2274-2281.
    • (2010) Obesity. , vol.18 , pp. 2274-2281
    • Gove, M.E.1    Sherry, C.L.2    Pini, M.3    Fantuzzi, G.4
  • 34
    • 0030955949 scopus 로고    scopus 로고
    • Leptin induces mitogenactivated protein kinase-dependent proliferation of C3H10T1/2 cells
    • Takahashi Y, Okimura Y, Mizuno I, et al. Leptin induces mitogenactivated protein kinase-dependent proliferation of C3H10T1/2 cells. J Biol Chem. 1997;272:12897-12900.
    • (1997) J Biol Chem. , vol.272 , pp. 12897-12900
    • Takahashi, Y.1    Okimura, Y.2    Mizuno, I.3
  • 35
    • 82555186955 scopus 로고    scopus 로고
    • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
    • Nguyen KD, Qiu Y, Cui X, et al. Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature. 2011;480:104-108.
    • (2011) Nature. , vol.480 , pp. 104-108
    • Nguyen, K.D.1    Qiu, Y.2    Cui, X.3
  • 36
    • 50949108719 scopus 로고    scopus 로고
    • Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
    • Murano I, Barbatelli G, Parisani V, et al. Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice. J Lipid Res. 2008;49:1562-1568.
    • (2008) J Lipid Res. , vol.49 , pp. 1562-1568
    • Murano, I.1    Barbatelli, G.2    Parisani, V.3
  • 37
    • 36049051889 scopus 로고    scopus 로고
    • Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis
    • Gruen ML, Hao M, Piston DW, Hasty AH. Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis. Am J Physiol Cell Physiol. 2007;293: C1481-C1488.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Gruen, M.L.1    Hao, M.2    Piston, D.W.3    Hasty, A.H.4
  • 38
    • 2342537773 scopus 로고    scopus 로고
    • From blood monocytes to adipose tissue-resident macrophages: Induction of diapedesis by human mature adipocytes
    • Curat CA, Miranville A, Sengenès C, et al. From blood monocytes to adipose tissue-resident macrophages: Induction of diapedesis by human mature adipocytes. Diabetes. 2004;53:1285-1292.
    • (2004) Diabetes. , vol.53 , pp. 1285-1292
    • Curat, C.A.1    Miranville, A.2    Sengenès, C.3
  • 39
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation- induced immunosuppression
    • Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation- induced immunosuppression. Nature. 1998;394:897-901.
    • (1998) Nature. , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3    Baker, R.J.4    Bloom, S.R.5    Lechler, R.I.6
  • 40
    • 77956202073 scopus 로고    scopus 로고
    • Leptin exacerbates sepsis-mediated morbidity and mortality
    • Shapiro NI, Khankin EV, Van Meurs M, et al. Leptin exacerbates sepsis-mediated morbidity and mortality. J Immunol. 2010;185: 517-524.
    • (2010) J Immunol. , vol.185 , pp. 517-524
    • Shapiro, N.I.1    Khankin, E.V.2    Van Meurs, M.3
  • 42
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF- and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF- and obesity-induced insulin resistance. Science. 1996;271:665-668.
    • (1996) Science. , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 43
    • 84872142459 scopus 로고    scopus 로고
    • JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
    • Han MS, Jung DY, Morel C, et al. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science. 2013;339:218-222.
    • (2013) Science. , vol.339 , pp. 218-222
    • Han, M.S.1    Jung, D.Y.2    Morel, C.3
  • 44
    • 0038809142 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 in obesity and insulin resistance
    • Sartipy P, Loskutoff DJ. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci U S A. 2003;100: 7265-7270.
    • (2003) Proc Natl Acad Sci U S A. , vol.100 , pp. 7265-7270
    • Sartipy, P.1    Loskutoff, D.J.2
  • 45
    • 77956396699 scopus 로고    scopus 로고
    • Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: Implications for systemic inflammation and insulin resistance
    • Yang H, Youm YH, Vandanmagsar B, et al. Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: Implications for systemic inflammation and insulin resistance. JImmunol. 2010;185: 1836-1845.
    • (2010) JImmunol. , vol.185 , pp. 1836-1845
    • Yang, H.1    Youm, Y.H.2    Vandanmagsar, B.3


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