Human neural stem cell-derived cultures in three-dimensional substrates form spontaneously functional neuronal networks

Journal of Tissue Engineering and Regenerative Medicine

Volumn 11, Issue 4, 2017, Pages 1022-1033

  Smith, Imogen ^a   Silveirinha, Vasco ^a   Stein, Jason L ^c   de la Torre Ubieta, Luis ^c   Farrimond, Jonathan A ^b   Williamson, Elizabeth M ^a   Whalley, Benjamin J ^a  

^a UNIVERSITY OF READING   (United Kingdom)

^b SUNTORY LTD   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

3D culture; biocompatible scaffold; differentiated neural stem cells; electrophysiology; neuronal networks; tissue engineering; toxicology

Indexed keywords

BIOCOMPATIBILITY; CELL ENGINEERING; COPYRIGHTS; CYTOLOGY; ELECTROPHYSIOLOGY; GENE EXPRESSION; NEURONS; OLIGONUCLEOTIDES; SCAFFOLDS (BIOLOGY); STEM CELLS;

3-D CULTURES; BIOCOMPATIBLE SCAFFOLDS; CELL/B.E; DIFFERENTIATED NEURAL STEM CELL; ELECTROPHYSIOLOGY; NEURAL STEM CELL; NEURONAL NETWORKS; THREE-DIMENSIONAL SUBSTRATES; TISSUES ENGINEERINGS; TOXICOLOGY;

NEURAL NETWORKS;

ARTICLE; CONTROLLED STUDY; CYTOSKELETON; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NEURAL STEM CELL; STEM CELL CULTURE; THREE DIMENSIONAL CULTURE; TWO DIMENSIONAL CULTURE; ACTION POTENTIAL; ALGORITHM; CELL CULTURE; CELL DIFFERENTIATION; CELL SHAPE; CYTOLOGY; ELECTRODE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; MACHINE LEARNING; PHENOTYPE; PHYSIOLOGY; PROCEDURES; TISSUE ENGINEERING; ULTRASTRUCTURE;

ACTION POTENTIALS; ALGORITHMS; CELL DIFFERENTIATION; CELL SHAPE; CELLS, CULTURED; ELECTRODES; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; MACHINE LEARNING; NERVE NET; NEURAL STEM CELLS; PHENOTYPE; TISSUE ENGINEERING;

EID: 84923532641     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.2001     Document Type: Article

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