Current status of human pluripotent stem cell based in vitro toxicity tests

Frontiers in Bioscience - Scholar

Volumn 5 S, Issue 1, 2013, Pages 118-133

  Klaric, Martina ^a   Winkler, Johannes ^b   Vojnits, Kinga ^a   Meganathan, Kesavan ^b   Jagtap, Smita ^b   Ensenat Waser, Roberto ^a   Hescheler, Juergen ^b   Sachinidis, Agapios ^b   Bremer Hoffmann, Susanne ^a  

^a JOINT RESEARCH CENTRE   (Italy)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Human pluripotent stem cells; In vitro toxicity testing; Review; Test development criteria

Indexed keywords

ACROSIN; ALPHA ACTININ; ALPHA FETOPROTEIN; BIOLOGICAL MARKER; CASPASE 3; CD34 ANTIGEN; CLUSTERIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DNA METHYLTRANSFERASE 3B; FOLLITROPIN RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 3BETA; NERVE CELL ADHESION MOLECULE; NESTIN; PROTEIN BCL 2; PROTEIN MLH1; PUM2 PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX2; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX1; TRANSCRIPTION FACTOR SOX3; TROPONIN I; TUBULIN; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ARTICLE; CARDIOTOXICITY; CELL DIFFERENTIATION; DEVELOPMENTAL TOXICITY; EMBRYO DEVELOPMENT; GENE EXPRESSION; HUMAN; IN VITRO STUDY; LIVER CELL; LIVER TOXICITY; LONG QT SYNDROME; MESENCHYME CELL; NEUROFILAMENT; NEUROTOXICITY; NONHUMAN; PLURIPOTENT STEM CELL; PRIMORDIAL GERM CELL; PROTEIN EXPRESSION; REPRODUCTIVE TOXICITY; SERTOLI CELL; SPERMATID; TOXICITY TESTING; DRUG EFFECT; DRUG TOXICITY; METHODOLOGY; REVIEW;

DRUG TOXICITY; HUMANS; PLURIPOTENT STEM CELLS; TOXICITY TESTS;

EID: 84883717955     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: 10.2741/s361     Document Type: Article

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