Species-specific differential ahr expression protects human neural progenitor cells against developmental neurotoxicity of PAHs

Environmental Health Perspectives

Volumn 118, Issue 11, 2010, Pages 1571-1577

  Gassmann, Kathrin ^a   Abel, Josef ^a   Bothe, Hanno ^a   Haarmann Stemmann, Thomas ^a   Merk, Hans F ^b   Quasthoff, Kim N ^a   Rockel, Thomas Dino ^a   Schreiber, Timm ^a   Fritsche, Ellen ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Ahr; Ahr knockout; Dnt; Neural progenitor cells; Neurospheres; PAH

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3 METHYLCHOLANTHRENE; 3' METHOXY 4' NITROFLAVONE; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; FLAVONE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHEMOSENSITIVITY; CONTROLLED STUDY; DEVELOPMENTAL NEUROTOXICITY; EMBRYO; HUMAN; HUMAN CELL; MALE; MOUSE; NEURAL STEM CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; TOXICITY TESTING; WILD TYPE;

ANIMALS; BENZO(A)PYRENE; CELLS, CULTURED; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; HUMANS; METHYLCHOLANTHRENE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVOUS SYSTEM; NEURONS; POLYCYCLIC HYDROCARBONS, AROMATIC; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; STEM CELLS; TETRACHLORODIBENZODIOXIN;

EID: 78149315835     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0901545     Document Type: Article

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