SCOPUS 정보 검색 플랫폼

Volumn 10, Issue 3, 2015, Pages 555-565

On the metabolically active form of metaglidasen: Improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles

(14) Laghezza, Antonio a Montanari, Roberta b Lavecchia, Antonio c Piemontese, Luca a Pochetti, Giorgio b Iacobazzi, Vito a,b Infantino, Vittoria b,d Capelli, Davide b De Bellis, Michela a Liantonio, Antonella a Pierno, Sabata a Tortorella, Paolo a Conte Camerino, Diana a Loiodice, Fulvio a

a UNIVERSITY OF BARI (Italy)

b CNR (Italy)

c UNIVERSITY OF NAPLES FEDERICO II (Italy)

d UNIVERSITY OF BASILICATA (Italy)

Author keywords

Molecular recognition; Ppar modulators; Receptors; X ray crystallography

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ARHALOFENATE; CHLORIDE CHANNEL; FIBRIC ACID DERIVATIVE; GLUCOSE; HALOFENIC ACID; HORMONE RECEPTOR BLOCKING AGENT; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIRINIXIC ACID; RECEPTOR SUBTYPE; RNA; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT;

ANIMAL TISSUE; ARTICLE; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; EXTENSOR DIGITORUM LONGUS MUSCLE; GLUCOSE BLOOD LEVEL; HEPG2 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; MEMBRANE CONDUCTANCE; MEMBRANE ELECTROPHYSIOLOGY; MUSCLE FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REAL TIME POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; MALE; METABOLISM; MOLECULAR DOCKING; WISTAR RAT;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; HEP G2 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; LIGANDS; MALE; MOLECULAR DOCKING SIMULATION; MUSCLE, SKELETAL; PPAR ALPHA; PPAR GAMMA; RATS, WISTAR;

EID: 84923367799 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201402462 Document Type: Article

Times cited : (27)

References (63)

1
- 18044376795
- J. P. Berger, T. E. Akiyama, P. T. Meinke, Trends Pharmacol. Sci. 2005, 26, 244-251.
- (2005) Trends Pharmacol. Sci. , vol.26 , pp. 244-251
- Berger, J.P.¹ Akiyama, T.E.² Meinke, P.T.³

2
- 0036183630
- J. Berger, D. E. Moller, Annu. Rev. Med. 2002, 53, 409-435.
- (2002) Annu. Rev. Med. , vol.53 , pp. 409-435
- Berger, J.¹ Moller, D.E.²

3
- 0006132932
- S. A. Kliewer, S. S. Sundseth, S. A. Jones, P. J. Brown, G. B. Wisely, C. S. Koble, P. Devchand, W. Wahli, T. M. Willson, J. M. Lenhard, J. M. Lehmann, Proc. Natl. Acad. Sci. USA 1997, 94, 4318-4323.
- (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4318-4323
- Kliewer, S.A.¹ Sundseth, S.S.² Jones, S.A.³ Brown, P.J.⁴ Wisely, G.B.⁵ Koble, C.S.⁶ Devchand, P.⁷ Wahli, W.⁸ Willson, T.M.⁹ Lenhard, J.M.¹⁰ Lehmann, J.M.¹¹

4
- 0032505096
- R. T. Nolte, G. B. Wisely, S. Westin, J. E. Cobb, M. H. Lambert, R. Kurokawa, M. G. Rosenfeld, T. M. Willson, C. K. Glass, M. V. Milburn, Nature 1998, 395, 137-143.
- (1998) Nature , vol.395 , pp. 137-143
- Nolte, R.T.¹ Wisely, G.B.² Westin, S.³ Cobb, J.E.⁴ Lambert, M.H.⁵ Kurokawa, R.⁶ Rosenfeld, M.G.⁷ Willson, T.M.⁸ Glass, C.K.⁹ Milburn, M.V.¹⁰

5
- 0033681001
- R. T. Gampe, Jr., V. G. Montana, M. H. Lambert, A. B. Miller, R. K. Bledsoe, M. V. Milburn, S. A. Kliewer, T. M. Willson, H. E. Xu, Mol. Cell 2000, 5, 545-555.
- (2000) Mol. Cell , vol.5 , pp. 545-555
- Gampe, R.T.¹ Montana, V.G.² Lambert, M.H.³ Miller, A.B.⁴ Bledsoe, R.K.⁵ Milburn, M.V.⁶ Kliewer, S.A.⁷ Willson, T.M.⁸ Xu, H.E.⁹

6
- 0033998334
- T. M. Willson, P. J. Brown, D. D. Sternbach, B. R. Henke, J. Med. Chem. 2000, 43, 527-550.
- (2000) J. Med. Chem. , vol.43 , pp. 527-550
- Willson, T.M.¹ Brown, P.J.² Sternbach, D.D.³ Henke, B.R.⁴

7
- 0033574663
- A Unified Nomenclature System for the Nuclear Receptor Superfamily: Nuclear Receptors Nomenclature Committee
- A Unified Nomenclature System for the Nuclear Receptor Superfamily: Nuclear Receptors Nomenclature Committee, Cell 1999, 97, 161-163.
- (1999) Cell , vol.97 , pp. 161-163

8
- 0029745382
- J. Berger, P. Bailey, C. Biswas, C. A. Cullinan, T. W. Doebber, N. S. Hayes, R. Saperstein, R. G. Smith, M. D. Leibowitz, Endocrinology 1996, 137, 4189-4195.
- (1996) Endocrinology , vol.137 , pp. 4189-4195
- Berger, J.¹ Bailey, P.² Biswas, C.³ Cullinan, C.A.⁴ Doebber, T.W.⁵ Hayes, N.S.⁶ Saperstein, R.⁷ Smith, R.G.⁸ Leibowitz, M.D.⁹

9
- 0028076266
- N. D. Oakes, C. J. Kennedy, A. B. Jenkins, D. R. Laybutt, D. J. Chisholm, E. W. Kraegen, Diabetes 1994, 43, 1203-1210.
- (1994) Diabetes , vol.43 , pp. 1203-1210
- Oakes, N.D.¹ Kennedy, C.J.² Jenkins, A.B.³ Laybutt, D.R.⁴ Chisholm, D.J.⁵ Kraegen, E.W.⁶

10
- 10744221639
- R. W. Nesto, D. Bell, R. O. Bonow, V. Fonseca, S. M. Grundy, E. S. Horton, M. L. Le Winter, D. Porte, C. F. Semenkovich, S. Smith, L. H. Young, R. Kahn, Diabetes Care 2004, 27, 256-263.
- (2004) Diabetes Care , vol.27 , pp. 256-263
- Nesto, R.W.¹ Bell, D.² Bonow, R.O.³ Fonseca, V.⁴ Grundy, S.M.⁵ Horton, E.S.⁶ Le Winter, M.L.⁷ Porte, D.⁸ Semenkovich, C.F.⁹ Smith, S.¹⁰ Young, L.H.¹¹ Kahn, R.¹²

11
- 48649095960
- S. E. Kahn, B. Zinman, J. M. Lachin, S. M. Haffner, W. H. Herman, R. R. Holman, B. G. Kravitz, D. Yu, M. A. Heise, R. P. Aftring, G. Viberti, Diabetes Care 2008, 31, 845-851.
- (2008) Diabetes Care , vol.31 , pp. 845-851
- Kahn, S.E.¹ Zinman, B.² Lachin, J.M.³ Haffner, S.M.⁴ Herman, W.H.⁵ Holman, R.R.⁶ Kravitz, B.G.⁷ Yu, D.⁸ Heise, M.A.⁹ Aftring, R.P.¹⁰ Viberti, G.¹¹

12
- 2642557181
- S. Rocchi, F. Picard, J. Vamecq, L. Gelman, N. Potier, D. Zeyer, L. Dubuquoy, P. Bac, M. F. Champy, K. D. Plunket, L. M. Leesnitzer, S. G. Blanchard, P. Desreumaux, D. Moras, J. P. Renaud, J. Auwerx, Mol. Cell 2001, 8, 737-747.
- (2001) Mol. Cell , vol.8 , pp. 737-747
- Rocchi, S.¹ Picard, F.² Vamecq, J.³ Gelman, L.⁴ Potier, N.⁵ Zeyer, D.⁶ Dubuquoy, L.⁷ Bac, P.⁸ Champy, M.F.⁹ Plunket, K.D.¹⁰ Leesnitzer, L.M.¹¹ Blanchard, S.G.¹² Desreumaux, P.¹³ Moras, D.¹⁴ Renaud, J.P.¹⁵ Auwerx, J.¹⁶

13
- 12444273748
- J. P. Berger, A. E. Petro, K. L. Macnaul, L. J. Kelly, B. B. Zhang, K. Richards, A. Elbrecht, B. A. Johnson, G. Zhou, T. W. Doebber, C. Biswas, M. Parikh, N. Sharma, M. R. Tanen, G. M. Thompson, J. Ventre, A. D. Adams, R. Mosley, R. S. Surwit, D. E. Moller, Mol. Endocrinol. 2003, 17, 662-676.
- (2003) Mol. Endocrinol. , vol.17 , pp. 662-676
- Berger, J.P.¹ Petro, A.E.² Macnaul, K.L.³ Kelly, L.J.⁴ Zhang, B.B.⁵ Richards, K.⁶ Elbrecht, A.⁷ Johnson, B.A.⁸ Zhou, G.⁹ Doebber, T.W.¹⁰ Biswas, C.¹¹ Parikh, M.¹² Sharma, N.¹³ Tanen, M.R.¹⁴ Thompson, G.M.¹⁵ Ventre, J.¹⁶ Adams, A.D.¹⁷ Mosley, R.¹⁸ Surwit, R.S.¹⁹ Moller, D.E.²⁰ more..

14
- 0037960935
- P. Misra, R. Chakrabarti, R. K. Vikramadithyan, G. Bolusu, S. Juluri, J. Hiriyan, C. Gershome, A. Rajjak, P. Kashireddy, S. Yu, S. Surapureddi, C. Qi, Y.-J. Zhu, M. S. Rao, J. K. Reddy, R. Ramanujam, J. Pharmacol. Exp. Ther. 2003, 306, 763-771.
- (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 763-771
- Misra, P.¹ Chakrabarti, R.² Vikramadithyan, R.K.³ Bolusu, G.⁴ Juluri, S.⁵ Hiriyan, J.⁶ Gershome, C.⁷ Rajjak, A.⁸ Kashireddy, P.⁹ Yu, S.¹⁰ Surapureddi, S.¹¹ Qi, C.¹² Zhu, Y.-J.¹³ Rao, M.S.¹⁴ Reddy, J.K.¹⁵ Ramanujam, R.¹⁶

15
- 2942724296
- H. Minoura, S. Takeshita, M. Ita, J. Hirosumi, M. Mabuchi, I. Kawamura, S. Nakajima, O. Nakayama, H. Kayakiri, T. Oku, A. Ohkubo-Suzuki, M. Fukagawa, H. Kojo, K. Hanioka, N. Yamasaki, T. Imoto, Y. Kobayashi, S. Mutoh, Eur. J. Pharmacol. 2004, 494, 273-281.
- (2004) Eur. J. Pharmacol. , vol.494 , pp. 273-281
- Minoura, H.¹ Takeshita, S.² Ita, M.³ Hirosumi, J.⁴ Mabuchi, M.⁵ Kawamura, I.⁶ Nakajima, S.⁷ Nakayama, O.⁸ Kayakiri, H.⁹ Oku, T.¹⁰ Ohkubo-Suzuki, A.¹¹ Fukagawa, M.¹² Kojo, H.¹³ Hanioka, K.¹⁴ Yamasaki, N.¹⁵ Imoto, T.¹⁶ Kobayashi, Y.¹⁷ Mutoh, S.¹⁸

16
- 10644293716
- J. J. Acton III, R. M. Black, A. B. Jones, D. E. Moller, L. Colwell, T. W. Doebber, K. L. MacNaul, J. Berger, H. B. Wood, Bioorg. Med. Chem. Lett. 2005, 15, 357-362.
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 357-362
- Acton, J.J.¹ Black, R.M.² Jones, A.B.³ Moller, D.E.⁴ Colwell, L.⁵ Doebber, T.W.⁶ MacNaul, K.L.⁷ Berger, J.⁸ Wood, H.B.⁹

17
- 25844513595
- J. F. Dropinski, T. Akiyama, M. Einstein, B. Habulihaz, T. Doebber, J. P. Berger, P. T. Meinke, G. Q. Shi, Bioorg. Med. Chem. Lett. 2005, 15, 5035-5038.
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 5035-5038
- Dropinski, J.F.¹ Akiyama, T.² Einstein, M.³ Habulihaz, B.⁴ Doebber, T.⁵ Berger, J.P.⁶ Meinke, P.T.⁷ Shi, G.Q.⁸

18
- 22344446185
- A. Reifel-Miller, K. Otto, E. Hawkins, R. Barr, W. R. Bensch, C. Bull, S. Dana, K. Klausing, J.-A. Martín, R. Rafaeloff-Phail, C. Rafizadeh-Montrose, G. Rhodes, R. Robey, I. Rojo, D. Rungta, D. Snyder, K. Wilbur, T. Zhang, R. Zink, A. Warshawsky, J. T. Brozinick, Mol. Endocrinol. 2005, 19, 1593-1605.
- (2005) Mol. Endocrinol. , vol.19 , pp. 1593-1605
- Reifel-Miller, A.¹ Otto, K.² Hawkins, E.³ Barr, R.⁴ Bensch, W.R.⁵ Bull, C.⁶ Dana, S.⁷ Klausing, K.⁸ Martín, J.-A.⁹ Rafaeloff-Phail, R.¹⁰ Rafizadeh-Montrose, C.¹¹ Rhodes, G.¹² Robey, R.¹³ Rojo, I.¹⁴ Rungta, D.¹⁵ Snyder, D.¹⁶ Wilbur, K.¹⁷ Zhang, T.¹⁸ Zink, R.¹⁹ Warshawsky, A.²⁰ Brozinick, J.T.²¹ more..

19
- 9644252788
- J. A. Martín, D. A. Brooks, L. Prieto, R. González, A. Torrado, I. Rojo, B. López de Uralde, C. Lamas, R. Ferritto, M. D. Martín-Ortega, J. Agejas, F. Parra, J. R. Rizzo, G. A. Rhodes, R. L. Robey, C. A. Alt, S. R. Wendel, T. Y. Zhang, A. Reifel-Miller, C. Montrose-Rafizadeh, J. T. Brozinick, E. Hawkins, E. A. Misener, D. A. Briere, R. Ardecky, J. D. Fraser, A. M. Warshawsky, Bioorg. Med. Chem. Lett. 2005, 15, 51-55.
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 51-55
- Martín, J.A.¹ Brooks, D.A.² Prieto, L.³ González, R.⁴ Torrado, A.⁵ Rojo, I.⁶ López De Uralde, B.⁷ Lamas, C.⁸ Ferritto, R.⁹ Martín-Ortega, M.D.¹⁰ Agejas, J.¹¹ Parra, F.¹² Rizzo, J.R.¹³ Rhodes, G.A.¹⁴ Robey, R.L.¹⁵ Alt, C.A.¹⁶ Wendel, S.R.¹⁷ Zhang, T.Y.¹⁸ Reifel-Miller, A.¹⁹ Montrose-Rafizadeh, C.²⁰ more..

20
- 33645394377
- E. Burgermeister, A. Schnoebelen, A. Flament, J. Benz, M. Stihle, B. Gsell, A. Rufer, A. Ruf, B. Kuhn, H. P. Märki, J. Mizrahi, E. Sebokova, E. Niesor, M. Meyer, Mol. Endocrinol. 2006, 20, 809-830.
- (2006) Mol. Endocrinol. , vol.20 , pp. 809-830
- Burgermeister, E.¹ Schnoebelen, A.² Flament, A.³ Benz, J.⁴ Stihle, M.⁵ Gsell, B.⁶ Rufer, A.⁷ Ruf, A.⁸ Kuhn, B.⁹ Märki, H.P.¹⁰ Mizrahi, J.¹¹ Sebokova, E.¹² Niesor, E.¹³ Meyer, M.¹⁴

21
- 33750580948
- T. Allen, F. Zhang, S. A. Moodie, L. E. Clemens, A. Smith, F. Gregoire, A. Bell, G. E. Muscat, T. A. Gustafson, Diabetes 2006, 55, 2523-2533.
- (2006) Diabetes , vol.55 , pp. 2523-2533
- Allen, T.¹ Zhang, F.² Moodie, S.A.³ Clemens, L.E.⁴ Smith, A.⁵ Gregoire, F.⁶ Bell, A.⁷ Muscat, G.E.⁸ Gustafson, T.A.⁹

22
- 35748941359
- Consortium of the French Ministry of Research and Technology
- M. C. Carmona, K. Louche, B. Lefebvre, A. Pilon, N. Hennuyer, V. Audinot-Bouchez, C. Fievet, G. Torpier, P. Formstecher, P. Renard, P. Lefebvre, C. Dacquet, B. Staels, L. Casteilla, L. Pénicaud, Consortium of the French Ministry of Research and Technology, Diabetes 2007, 56, 2797-2808.
- (2007) Diabetes , vol.56 , pp. 2797-2808
- Carmona, M.C.¹ Louche, K.² Lefebvre, B.³ Pilon, A.⁴ Hennuyer, N.⁵ Audinot-Bouchez, V.⁶ Fievet, C.⁷ Torpier, G.⁸ Formstecher, P.⁹ Renard, P.¹⁰ Lefebvre, P.¹¹ Dacquet, C.¹² Staels, B.¹³ Casteilla, L.¹⁴ Pénicaud, L.¹⁵

23
- 67649366027
- M. K. Kim, Y. N. Chae, H. S. Kim, S.-h. Choi, M. H. Son, S. H. Kim, J. K. Kim, H. S. Moon, S. K. Park, Y. A. Shin, J. G. Kim, C. H. Lee, J. I. Lim, C. Y. Shin, Arch. Pharmacal Res. 2009, 32, 721-727.
- (2009) Arch. Pharmacal Res. , vol.32 , pp. 721-727
- Kim, M.K.¹ Chae, Y.N.² Kim, H.S.³ Choi, S.-H.⁴ Son, M.H.⁵ Kim, S.H.⁶ Kim, J.K.⁷ Moon, H.S.⁸ Park, S.K.⁹ Shin, Y.A.¹⁰ Kim, J.G.¹¹ Lee, C.H.¹² Lim, J.I.¹³ Shin, C.Y.¹⁴

24
- 60849095073
- A. Motani, Z. Wang, J. Weiszmann, L. R. McGee, G. Lee, Q. Liu, J. Staunton, Z. Fang, H. Fuentes, M. Lindstrom, J. Liu, D. H. Biermann, J. Jaen, N. P. Walker, R. M. Learned, J. L. Chen, Y. Li, J. Mol. Biol. 2009, 386, 1301-1311.
- (2009) J. Mol. Biol. , vol.386 , pp. 1301-1311
- Motani, A.¹ Wang, Z.² Weiszmann, J.³ McGee, L.R.⁴ Lee, G.⁵ Liu, Q.⁶ Staunton, J.⁷ Fang, Z.⁸ Fuentes, H.⁹ Lindstrom, M.¹⁰ Liu, J.¹¹ Biermann, D.H.¹² Jaen, J.¹³ Walker, N.P.¹⁴ Learned, R.M.¹⁵ Chen, J.L.¹⁶ Li, Y.¹⁷

25
- 67649598394
- F. M. Gregoire, F. Zhang, H. J. Clarke, T. A. Gustafson, D. D. Sears, S. Favelyukis, J. Lenhard, D. Rentzeperis, L. E. Clemens, Y. Mu, B. E. Lavan, Mol. Endocrinol. 2009, 23, 975-988.
- (2009) Mol. Endocrinol. , vol.23 , pp. 975-988
- Gregoire, F.M.¹ Zhang, F.² Clarke, H.J.³ Gustafson, T.A.⁴ Sears, D.D.⁵ Favelyukis, S.⁶ Lenhard, J.⁷ Rentzeperis, D.⁸ Clemens, L.E.⁹ Mu, Y.¹⁰ Lavan, B.E.¹¹

26
- 0015621328
- W. S. Aronow, P. R. Harding, M. Khursheed, J. S. Vangrow, N. P. Papageorge's, J. Mays, Clin. Pharmacol. Ther. 1973, 14, 358-365.
- (1973) Clin. Pharmacol. Ther. , vol.14 , pp. 358-365
- Aronow, W.S.¹ Harding, P.R.² Khursheed, M.³ Vangrow, J.S.⁴ Papageorge's, N.P.⁵ Mays, J.⁶

27
- 0015624489
- W. S. Aronow, P. R. Harding, M. Khursheed, J. S. Vangrow, N. P. Papageorge's, Clin. Pharmacol. Ther. 1973, 14, 371-373.
- (1973) Clin. Pharmacol. Ther. , vol.14 , pp. 371-373
- Aronow, W.S.¹ Harding, P.R.² Khursheed, M.³ Vangrow, J.S.⁴ Papageorge's, N.P.⁵

28
- 84923359488
- (Boehringer Ingelheim International GmbH), Int. PCT Pub No.
- T. Rauch, B. S. Hamilton, M. Tsutsumi (Boehringer Ingelheim International GmbH), Int. PCT Pub. No. WO2013167554A1 20131114, 2013.
- (2013)
- Rauch, T.¹ Hamilton, B.S.² Tsutsumi, M.³

29
- 84923357369
- (Boehringer Ingelheim International GmbH), Int. PCT Pub No.
- B. S. Hamilton, T. Rauch, M. Tsutsumi (Boehringer Ingelheim International GmbH), Int. PCT Pub. No. WO2012059416A1 20120510, 2012.
- (2012)
- Hamilton, B.S.¹ Rauch, T.² Tsutsumi, M.³

30
- 84857753689
- A. Chandalia, H. J. Clarke, L. E. Clemens, B. Pandey, V. Vicena, P. Lee, B. E. Lavan, F. M. Gregoire, PPAR Res. 2009, 706852.
- (2009) PPAR Res. , pp. 706852
- Chandalia, A.¹ Clarke, H.J.² Clemens, L.E.³ Pandey, B.⁴ Vicena, V.⁵ Lee, P.⁶ Lavan, B.E.⁷ Gregoire, F.M.⁸

31
- 84923361591
- (Metabolex Inc., Hayward, USA), US Pat. No.
- K. L. Luskey, J. Luo (Metabolex Inc., Hayward, USA), US Pat. No. 6.262.118B1, 2001.
- (2001)
- Luskey, K.L.¹ Luo, J.²

32
- 84923350977
- (Metabolex Inc., Hayward, USA), US Pat. No.
- Y. Zhu, P. Cheng, X. Chen, J. Ma, Z. Zhao (Metabolex Inc., Hayward, USA), US Pat. No. 2007/0072858A1, 2007.
- (2007)
- Zhu, Y.¹ Cheng, P.² Chen, X.³ Ma, J.⁴ Zhao, Z.⁵

33
- 0023258874
- D. R. Feller, V. S. Kamanna, H. A. Newman, K. J. Romstedt, D. T. Witiak, G. Bettoni, S. H. Bryant, D. Conte-Camerino, F. Loiodice, V. Tortorella, J. Med. Chem. 1987, 30, 1265-1267.
- (1987) J. Med. Chem. , vol.30 , pp. 1265-1267
- Feller, D.R.¹ Kamanna, V.S.² Newman, H.A.³ Romstedt, K.J.⁴ Witiak, D.T.⁵ Bettoni, G.⁶ Bryant, S.H.⁷ Conte-Camerino, D.⁸ Loiodice, F.⁹ Tortorella, V.¹⁰

34
- 0023262743
- G. Bettoni, F. Loiodice, V. Tortorella, D. Conte-Camerino, M. Mambrini, E. Ferrannini, S. H. Bryant, J. Med. Chem. 1987, 30, 1267-1270.
- (1987) J. Med. Chem. , vol.30 , pp. 1267-1270
- Bettoni, G.¹ Loiodice, F.² Tortorella, V.³ Conte-Camerino, D.⁴ Mambrini, M.⁵ Ferrannini, E.⁶ Bryant, S.H.⁷

35
- 0037051164
- C. Hodel, Toxicol. Lett. 2002, 128, 159-168.
- (2002) Toxicol. Lett. , vol.128 , pp. 159-168
- Hodel, C.¹

36
- 33845191992
- S. Pierno, M. P. Didonna, V. Cippone, A. De Luca, M. Pisoni, A. Frigeri, G. P. Nicchia, M. Svelto, G. Chiesa, C. Sirtori, E. Scanziani, C. Rizzo, D. De Vito, D. Conte Camerino, Br. J. Pharmacol. 2006, 149, 909-919.
- (2006) Br. J. Pharmacol. , vol.149 , pp. 909-919
- Pierno, S.¹ Didonna, M.P.² Cippone, V.³ De Luca, A.⁴ Pisoni, M.⁵ Frigeri, A.⁶ Nicchia, G.P.⁷ Svelto, M.⁸ Chiesa, G.⁹ Sirtori, C.¹⁰ Scanziani, E.¹¹ Rizzo, C.¹² De Vito, D.¹³ Conte Camerino, D.¹⁴

37
- 84923365659
- (Metabolex Inc., Hayward, USA), Int. PCT Pub. No.
- P. Cheng, J. Ma, X. Chen, Y. Zhu, Z. Zhao (Metabolex Inc., Hayward, USA), Int. PCT Pub. No. WO2007/038277A2, 2007.
- (2007)
- Cheng, P.¹ Ma, J.² Chen, X.³ Zhu, Y.⁴ Zhao, Z.⁵

38
- 0037149634
- M. Wolter, G. Nordmann, G. E. Job, S. L. Buchwald, Org. Lett. 2002, 4, 973-976.
- (2002) Org. Lett. , vol.4 , pp. 973-976
- Wolter, M.¹ Nordmann, G.² Job, G.E.³ Buchwald, S.L.⁴

39
- 70349207158
- M. M. Cavalluzzi, C. Bruno, G. Lentini, A. Lovece, A. Catalano, A. Carocci, C. Franchini, Tetrahedron: Asymmetry 2009, 20, 1984-1991.
- (2009) Tetrahedron: Asymmetry , vol.20 , pp. 1984-1991
- Cavalluzzi, M.M.¹ Bruno, C.² Lentini, G.³ Lovece, A.⁴ Catalano, A.⁵ Carocci, A.⁶ Franchini, C.⁷

40
- 75449092835
- Q. He, Y.-F. Peng, S. Rohani, Chirality 2010, 22, 16-23.
- (2010) Chirality , vol.22 , pp. 16-23
- He, Q.¹ Peng, Y.-F.² Rohani, S.³

41
- 23944473582
- A. Pinelli, C. Godio, A. Laghezza, N. Mitro, G. Fracchiolla, V. Tortorella, A. Lavecchia, E. Novellino, J.-C. Fruchart, B. Staels, M. Crestani, F. Loiodice, J. Med. Chem. 2005, 48, 5509-5519.
- (2005) J. Med. Chem. , vol.48 , pp. 5509-5519
- Pinelli, A.¹ Godio, C.² Laghezza, A.³ Mitro, N.⁴ Fracchiolla, G.⁵ Tortorella, V.⁶ Lavecchia, A.⁷ Novellino, E.⁸ Fruchart, J.-C.⁹ Staels, B.¹⁰ Crestani, M.¹¹ Loiodice, F.¹²

42
- 84872318231
- A. Laghezza, G. Pochetti, A. Lavecchia, G. Fracchiolla, S. Faliti, L. Piemontese, C. Di Giovanni, V. Iacobazzi, V. Infantino, R. Montanari, D. Capelli, P. Tortorella, F. Loiodice, J. Med. Chem. 2013, 56, 60-72.
- (2013) J. Med. Chem. , vol.56 , pp. 60-72
- Laghezza, A.¹ Pochetti, G.² Lavecchia, A.³ Fracchiolla, G.⁴ Faliti, S.⁵ Piemontese, L.⁶ Di Giovanni, C.⁷ Iacobazzi, V.⁸ Infantino, V.⁹ Montanari, R.¹⁰ Capelli, D.¹¹ Tortorella, P.¹² Loiodice, F.¹³

43
- 84874997645
- C. Temporini, G. Pochetti, G. Fracchiolla, L. Piemontese, R. Montanari, R. Moaddel, A. Laghezza, F. Altieri, L. Cervoni, D. Ubiali, E. Prada, F. Loiodice, G. Massolini, E. Calleri, J. Chromatogr. A 2013, 1284, 36-43.
- (2013) J. Chromatogr. A , vol.1284 , pp. 36-43
- Temporini, C.¹ Pochetti, G.² Fracchiolla, G.³ Piemontese, L.⁴ Montanari, R.⁵ Moaddel, R.⁶ Laghezza, A.⁷ Altieri, F.⁸ Cervoni, L.⁹ Ubiali, D.¹⁰ Prada, E.¹¹ Loiodice, F.¹² Massolini, G.¹³ Calleri, E.¹⁴

44
- 84855839232
- L. Porcelli, F. Gilardi, A. Laghezza, L. Piemontese, N. Mitro, A. Azzariti, F. Altieri, L. Cervoni, G. Fracchiolla, M. Giudici, U. Guerrini, A. Lavecchia, R. Montanari, C. Di Giovanni, A. Paradiso, G. Pochetti, G. M. Simone, P. Tortorella, M. Crestani, F. Loiodice, J. Med. Chem. 2012, 55, 37-54.
- (2012) J. Med. Chem. , vol.55 , pp. 37-54
- Porcelli, L.¹ Gilardi, F.² Laghezza, A.³ Piemontese, L.⁴ Mitro, N.⁵ Azzariti, A.⁶ Altieri, F.⁷ Cervoni, L.⁸ Fracchiolla, G.⁹ Giudici, M.¹⁰ Guerrini, U.¹¹ Lavecchia, A.¹² Montanari, R.¹³ Di Giovanni, C.¹⁴ Paradiso, A.¹⁵ Pochetti, G.¹⁶ Simone, G.M.¹⁷ Tortorella, P.¹⁸ Crestani, M.¹⁹ Loiodice, F.²⁰ more..

45
- 84858070063
- E. Calleri, G. Fracchiolla, R. Montanari, G. Pochetti, A. Lavecchia, F. Loiodice, A. Laghezza, L. Piemontese, G. Massolini, C. Temporini, J. Chromatogr. A 2012, 1232, 84-92.
- (2012) J. Chromatogr. A , vol.1232 , pp. 84-92
- Calleri, E.¹ Fracchiolla, G.² Montanari, R.³ Pochetti, G.⁴ Lavecchia, A.⁵ Loiodice, F.⁶ Laghezza, A.⁷ Piemontese, L.⁸ Massolini, G.⁹ Temporini, C.¹⁰

46
- 0030890262
- S. M. Rangwala, M. L. O'Brien, V. Tortorella, A. Longo, F. Loiodice, D. J. Noonan, D. R. Feller, Chirality 1997, 9, 37-47.
- (1997) Chirality , vol.9 , pp. 37-47
- Rangwala, S.M.¹ O'Brien, M.L.² Tortorella, V.³ Longo, A.⁴ Loiodice, F.⁵ Noonan, D.J.⁶ Feller, D.R.⁷

47
- 69949154243
- V. Iacobazzi, P. Convertini, V. Infantino, P. Scarcia, S. Todisco, F. Palmieri, Biochem. Biophys. Res. Commun. 2009, 388, 643-647.
- (2009) Biochem. Biophys. Res. Commun. , vol.388 , pp. 643-647
- Iacobazzi, V.¹ Convertini, P.² Infantino, V.³ Scarcia, P.⁴ Todisco, S.⁵ Palmieri, F.⁶

48
- 81855201915
- C. Indiveri, V. Iacobazzi, A. Tonazzi, N. Giangregorio, V. Infantino, P. Convertini, L. Console, F. Palmieri, Mol. Aspects Med. 2011, 32, 223-233.
- (2011) Mol. Aspects Med. , vol.32 , pp. 223-233
- Indiveri, C.¹ Iacobazzi, V.² Tonazzi, A.³ Giangregorio, N.⁴ Infantino, V.⁵ Convertini, P.⁶ Console, L.⁷ Palmieri, F.⁸

49
- 80054911951
- R. A. Laskowski, M. B. Swindells, J. Chem. Inf. Model. 2011, 51, 2778-2786.
- (2011) J. Chem. Inf. Model. , vol.51 , pp. 2778-2786
- Laskowski, R.A.¹ Swindells, M.B.²

50
- 77954941113
- J. H. Choi, A. S. Banks, J. L. Estall, S. Kajimura, P. Boström, D. Laznik, J. L. Ruas, M. J. Chalmers, T. M. Kamenecka, M. Blüher, P. R. Griffin, B. M. Spiegelman, Nature 2010, 466, 451-456.
- (2010) Nature , vol.466 , pp. 451-456
- Choi, J.H.¹ Banks, A.S.² Estall, J.L.³ Kajimura, S.⁴ Boström, P.⁵ Laznik, D.⁶ Ruas, J.L.⁷ Chalmers, M.J.⁸ Kamenecka, T.M.⁹ Blüher, M.¹⁰ Griffin, P.R.¹¹ Spiegelman, B.M.¹²

51
- 68749085959
- S. Pierno, G. M. Camerino, V. Cippone, J.-F. Rolland, J.-F. Desaphy, A. De Luca, A. Liantonio, G. Bianco, J. D. Kunic, A. L. George, Jr., D. Conte Camerino, Br. J. Pharmacol. 2009, 156, 1206-1215.
- (2009) Br. J. Pharmacol. , vol.156 , pp. 1206-1215
- Pierno, S.¹ Camerino, G.M.² Cippone, V.³ Rolland, J.-F.⁴ Desaphy, J.-F.⁵ De Luca, A.⁶ Liantonio, A.⁷ Bianco, G.⁸ Kunic, J.D.⁹ George, A.L.¹⁰ Conte Camerino, D.¹¹

52
- 70350041556
- G. Fracchiolla, A. Laghezza, L. Piemontese, P. Tortorella, F. Mazza, R. Montanari, G. Pochetti, A. Lavecchia, E. Novellino, S. Pierno, D. Conte Camerino, F. Loiodice, J. Med. Chem. 2009, 52, 6382-6393.
- (2009) J. Med. Chem. , vol.52 , pp. 6382-6393
- Fracchiolla, G.¹ Laghezza, A.² Piemontese, L.³ Tortorella, P.⁴ Mazza, F.⁵ Montanari, R.⁶ Pochetti, G.⁷ Lavecchia, A.⁸ Novellino, E.⁹ Pierno, S.¹⁰ Conte Camerino, D.¹¹ Loiodice, F.¹²

53
- 0033939421
- M. W. Berchtold, H. Brinkmeier, M. M ntener, Physiol. Rev. 2000, 80, 1215-1265.
- (2000) Physiol. Rev. , vol.80 , pp. 1215-1265
- Berchtold, M.W.¹ Brinkmeier, H.² Müntener, M.³

54
- 35648980456
- S. Pierno, J. F. Desaphy, A. Liantonio, A. De Luca, A. Zarrilli, L. Mastrofrancesco, G. Procino, G. Valenti, D. Conte Camerino, J. Physiol. 2007, 584, 983-995.
- (2007) J. Physiol. , vol.584 , pp. 983-995
- Pierno, S.¹ Desaphy, J.F.² Liantonio, A.³ De Luca, A.⁴ Zarrilli, A.⁵ Mastrofrancesco, L.⁶ Procino, G.⁷ Valenti, G.⁸ Conte Camerino, D.⁹

55
- 34447128782
- G. Pochetti, C. Godio, N. Mitro, D. Caruso, A. Galmozzi, S. Scurati, F. Loiodice, G. Fracchiolla, P. Tortorella, A. Laghezza, A. Lavecchia, E. Novellino, F. Mazza, M. Crestani, J. Biol. Chem. 2007, 282, 17314-17324.
- (2007) J. Biol. Chem. , vol.282 , pp. 17314-17324
- Pochetti, G.¹ Godio, C.² Mitro, N.³ Caruso, D.⁴ Galmozzi, A.⁵ Scurati, S.⁶ Loiodice, F.⁷ Fracchiolla, G.⁸ Tortorella, P.⁹ Laghezza, A.¹⁰ Lavecchia, A.¹¹ Novellino, E.¹² Mazza, F.¹³ Crestani, M.¹⁴

56
- 0003076963
- A. G. W. Leslie, Newsl. Protein Crystallogr. 1992, 26, 27-33.
- (1992) Newsl. Protein Crystallogr. , vol.26 , pp. 27-33
- Leslie, A.G.W.¹

57
- 84920325457
- J. Navaza, Acta Crystallogr. Sect. A 1994, 50, 157-163.
- (1994) Acta Crystallogr. Sect. A , vol.50 , pp. 157-163
- Navaza, J.¹

58
- 76449098262
- P. D. Adams, P. V. Afonine, G. Bunkóczi, V. B. Chen, I. W. Davis, N. Echols, J. J. Headd, L.-W. Hung, G. J. Kapral, R. W. Grosse-Kunstleve, A. J. McCoy, N. W. Moriarty, R. Oeffner, R. J. Read, D. C. Richardson, J. S. Richardson, T. C. Terwilliger, P. H. Zwart, Acta Crystallogr. Sect. D 2010, 66, 213-221.
- (2010) Acta Crystallogr. Sect. D , vol.66 , pp. 213-221
- Adams, P.D.¹ Afonine, P.V.² Bunkóczi, G.³ Chen, V.B.⁴ Davis, I.W.⁵ Echols, N.⁶ Headd, J.J.⁷ Hung, L.-W.⁸ Kapral, G.J.⁹ Grosse-Kunstleve, R.W.¹⁰ McCoy, A.J.¹¹ Moriarty, N.W.¹² Oeffner, R.¹³ Read, R.J.¹⁴ Richardson, D.C.¹⁵ Richardson, J.S.¹⁶ Terwilliger, T.C.¹⁷ Zwart, P.H.¹⁸

59
- 0032740190
- E. Raspé, L. Madsen, A. M. Lefebvre, I. Leitersdorf, L. Gelman, J. Peinado-Onsurbe, J. Dallongeville, J.-C. Fruchart, R. Berge, B. Staels, J. Lipid Res. 1999, 40, 2099-2110.
- (1999) J. Lipid Res. , vol.40 , pp. 2099-2110
- Raspé, E.¹ Madsen, L.² Lefebvre, A.M.³ Leitersdorf, I.⁴ Gelman, L.⁵ Peinado-Onsurbe, J.⁶ Dallongeville, J.⁷ Fruchart, J.-C.⁸ Berge, R.⁹ Staels, B.¹⁰

60
- 0024448155
- T. Hollon, F. K. Yoshimura, Anal. Biochem. 1989, 182, 411-418.
- (1989) Anal. Biochem. , vol.182 , pp. 411-418
- Hollon, T.¹ Yoshimura, F.K.²

61
- 67649197322
- V. Iacobazzi, V. Infantino, P. Convertini, A. Vozza, G. Agrimi, F. Palmieri, Biochem. Biophys. Res. Commun. 2009, 386, 186-191.
- (2009) Biochem. Biophys. Res. Commun. , vol.386 , pp. 186-191
- Iacobazzi, V.¹ Infantino, V.² Convertini, P.³ Vozza, A.⁴ Agrimi, G.⁵ Palmieri, F.⁶

62
- 78650875617
- P. Convertini, V. Infantino, F. Bisaccia, F. Palmieri, V. Iacobazzi, Biochem. Biophys. Res. Commun. 2011, 404, 376-381.
- (2011) Biochem. Biophys. Res. Commun. , vol.404 , pp. 376-381
- Convertini, P.¹ Infantino, V.² Bisaccia, F.³ Palmieri, F.⁴ Iacobazzi, V.⁵

63
- 2942630516
- B. Fraysse, J. F. Desaphy, S. Pierno, A. De Luca, A. Liantonio, C. I. Mitolo, D. Conte Camerino, FASEB J. 2003, 17, 1916-1918.
- (2003) FASEB J. , vol.17 , pp. 1916-1918
- Fraysse, B.¹ Desaphy, J.F.² Pierno, S.³ De Luca, A.⁴ Liantonio, A.⁵ Mitolo, C.I.⁶ Conte Camerino, D.⁷

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