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Volumn 40, Issue 11, 1999, Pages 2099-2110

Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARα activation

Author keywords

3 thia fatty acids; Gene expression; Lipoprotein lipase; Lipoprotein metabolism; Peroxisome proliferator activated receptors

Indexed keywords

ACYL COENZYME A OXIDASE; APOLIPOPROTEIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN A4; APOLIPOPROTEIN B; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; CARNITINE PALMITOYLTRANSFERASE; CHOLESTEROL; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIPID; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; THIOACETIC ACID; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL;

EID: 0032740190     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (123)

References (72)
  • 1
    • 0028226236 scopus 로고
    • Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acids)
    • Berge, R. K., and E. Hvattum. 1994. Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acids). Pharmacol. Ther. 61: 345-383.
    • (1994) Pharmacol. Ther. , vol.61 , pp. 345-383
    • Berge, R.K.1    Hvattum, E.2
  • 2
    • 0026074550 scopus 로고
    • Peroxisome proliferating sulphur- and oxysubstituted fatty acid analogues are activated to acyl coenzyme A thioesters
    • Aarsland, A., and R. Berge. 1990. Peroxisome proliferating sulphur- and oxysubstituted fatty acid analogues are activated to acyl coenzyme A thioesters. Biochem. Pharmacol. 41: 53-61.
    • (1990) Biochem. Pharmacol. , vol.41 , pp. 53-61
    • Aarsland, A.1    Berge, R.2
  • 3
    • 0025223344 scopus 로고
    • Morphologic effects of sulfur-substituted fatty acids on rat hepatocytes with special reference to proliferation of peroxisomes and mitochondria
    • Kryvi, H., A. Aarsland, and R. K. Berge. 1990. Morphologic effects of sulfur-substituted fatty acids on rat hepatocytes with special reference to proliferation of peroxisomes and mitochondria. J. Struct. Biol. 103: 257-265.
    • (1990) J. Struct. Biol. , vol.103 , pp. 257-265
    • Kryvi, H.1    Aarsland, A.2    Berge, R.K.3
  • 4
    • 0025007395 scopus 로고
    • Regulation of fatty acid oxidation and triglyceride and phospolipid metabolism by hypolipidemic sulfur-substituted fatty acid analogues
    • Skorve, J., D. Asiedu, A. Rustan, C. Drevon, A. Al-Shurbaji, and R. K. Berge. 1990. Regulation of fatty acid oxidation and triglyceride and phospolipid metabolism by hypolipidemic sulfur-substituted fatty acid analogues. J. Lipid Res. 31: 1627-1635.
    • (1990) J. Lipid Res. , vol.31 , pp. 1627-1635
    • Skorve, J.1    Asiedu, D.2    Rustan, A.3    Drevon, C.4    Al-Shurbaji, A.5    Berge, R.K.6
  • 5
    • 0028855179 scopus 로고
    • Hepatic fatty acid metabolism as a determinant of plasma and liver triacylglycerol levels. Studies on tetradecylthioacetic and tetradecylthiopropionic acids
    • Asiedu, D. K., A. Al-Shurbaji, A. C. Rustan, I. Björkhem, and R. K. Berge. 1995. Hepatic fatty acid metabolism as a determinant of plasma and liver triacylglycerol levels. Studies on tetradecylthioacetic and tetradecylthiopropionic acids. Eur. J. Biochem. 227: 715-722.
    • (1995) Eur. J. Biochem. , vol.227 , pp. 715-722
    • Asiedu, D.K.1    Al-Shurbaji, A.2    Rustan, A.C.3    Björkhem, I.4    Berge, R.K.5
  • 6
    • 0028148941 scopus 로고
    • Coordinate induction of hepatic fatty acyl-coa oxidase and P4504A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulfur-substituted fatty acid analogues
    • Demoz, A., H. Vaagenes, N. Aarsaether, E. Hvattum, J. Skorve, M. Gottlicher, J. R. Lillehaug, G. G. Gibson, J. A. Gustafsson, S. Hood, and R. K. Berge. 1994. Coordinate induction of hepatic fatty acyl-CoA oxidase and P4504A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulfur-substituted fatty acid analogues. Xenobiotica. 24: 943-956.
    • (1994) Xenobiotica , vol.24 , pp. 943-956
    • Demoz, A.1    Vaagenes, H.2    Aarsaether, N.3    Hvattum, E.4    Skorve, J.5    Gottlicher, M.6    Lillehaug, J.R.7    Gibson, G.G.8    Gustafsson, J.A.9    Hood, S.10    Berge, R.K.11
  • 7
    • 0032946594 scopus 로고    scopus 로고
    • Mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A synthase and carnitine palmitoyltransferase II as potential control sites for ketogenesis during mitochondrion and peroxisome proliferation
    • Madsen, L., A. Garras, G. Asins, D. Serra, F. Hegardt, and R. K. Berge. 1999. Mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A synthase and carnitine palmitoyltransferase II as potential control sites for ketogenesis during mitochondrion and peroxisome proliferation. Biochem. Pharmacol. 57: 1011-1019.
    • (1999) Biochem. Pharmacol. , vol.57 , pp. 1011-1019
    • Madsen, L.1    Garras, A.2    Asins, G.3    Serra, D.4    Hegardt, F.5    Berge, R.K.6
  • 8
    • 0032982919 scopus 로고    scopus 로고
    • 3-Thia fatty acids treatment, in contrast to eicosapentaenoic acid and starvation, induces gene expression of carnitine palmitoyltransferase II in rat liver
    • Madsen, L., and R. K. Berge. 1999. 3-Thia fatty acids treatment, in contrast to eicosapentaenoic acid and starvation, induces gene expression of carnitine palmitoyltransferase II in rat liver. Lipids. 34: 447-456.
    • (1999) Lipids , vol.34 , pp. 447-456
    • Madsen, L.1    Berge, R.K.2
  • 9
    • 0031775378 scopus 로고    scopus 로고
    • Early modulation of genes encoding peroxisomal and mitochondrial β-oxidation enzymes by 3-thia fatty acids
    • Vaagenes, H., L. Madsen, D. K. Asiedu, J. R. Lillehaugh, and R. K. Berge. 1998. Early modulation of genes encoding peroxisomal and mitochondrial β-oxidation enzymes by 3-thia fatty acids. Biochem. Pharmacol. 56: 1571-1582.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 1571-1582
    • Vaagenes, H.1    Madsen, L.2    Asiedu, D.K.3    Lillehaugh, J.R.4    Berge, R.K.5
  • 11
    • 0001474759 scopus 로고
    • Familial disorders of high density lipoprotein metabolism
    • C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York
    • Breslow, J. L. 1989. Familial disorders of high density lipoprotein metabolism. In The Metabolic Basis of Inherited Disease. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York. Vol I, 1251-1266.
    • (1989) The Metabolic Basis of Inherited Disease , vol.1 , pp. 1251-1266
    • Breslow, J.L.1
  • 12
    • 0027183380 scopus 로고
    • Transgenic mouse models of lipoprotein metabolism and atherosclerosis
    • Breslow, J. L. 1993. Transgenic mouse models of lipoprotein metabolism and atherosclerosis. Proc. Natl. Acad. Sci. USA. 90: 8314-8318.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8314-8318
    • Breslow, J.L.1
  • 13
    • 0032005605 scopus 로고    scopus 로고
    • High density lipoproteins and coronary heart disease. Future prospects in gene therapy
    • Fruchart, J-C., and P. Duriez. 1998. High density lipoproteins and coronary heart disease. Future prospects in gene therapy. Biochimie. 80: 167-172.
    • (1998) Biochimie. , vol.80 , pp. 167-172
    • Fruchart, J.-C.1    Duriez, P.2
  • 14
    • 0029887095 scopus 로고    scopus 로고
    • Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production
    • Plump, A. S., S. K. Erickson, W. Weng, J. S. Partin, J. L. Breslow, and D. L. Williams. 1996. Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production. J. Clin. Invest. 97: 2660-2671.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2660-2671
    • Plump, A.S.1    Erickson, S.K.2    Weng, W.3    Partin, J.S.4    Breslow, J.L.5    Williams, D.L.6
  • 15
    • 0018567934 scopus 로고
    • Apolipoprotein C-II and C-III levels in hyperlipoproteinemia
    • Schonfeld, G., P. I. Georges, J. Miller, P. Reilly, and J. Witztum. 1979. Apolipoprotein C-II and C-III levels in hyperlipoproteinemia. Metabolism. 28: 1001-1009.
    • (1979) Metabolism , vol.28 , pp. 1001-1009
    • Schonfeld, G.1    Georges, P.I.2    Miller, J.3    Reilly, P.4    Witztum, J.5
  • 16
    • 0018732127 scopus 로고
    • Hypertriglyceridaemia associated with an abnormal triglyceride-rich lipoprotein carrying excess apolipoprotein C-III
    • Stocks, J., G. Holdsworth, and D. J. Galton. 1979. Hypertriglyceridaemia associated with an abnormal triglyceride-rich lipoprotein carrying excess apolipoprotein C-III. Lancet. ii: 667-671.
    • (1979) Lancet , vol.2 , pp. 667-671
    • Stocks, J.1    Holdsworth, G.2    Galton, D.J.3
  • 17
    • 0023875069 scopus 로고
    • Independent regulation of plasma apolipoprotein C-II and C-III concentrations in very low density and high density lipoproteins: Implications for the regulation of the catabolism of these lipoproteins
    • Le, N-A., J. C. Gibson, and H. N. Ginsberg. 1988. Independent regulation of plasma apolipoprotein C-II and C-III concentrations in very low density and high density lipoproteins: implications for the regulation of the catabolism of these lipoproteins. J. Lipid Res. 29: 669-677.
    • (1988) J. Lipid Res. , vol.29 , pp. 669-677
    • Le, N.-A.1    Gibson, J.C.2    Ginsberg, H.N.3
  • 18
    • 0025030698 scopus 로고
    • Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice
    • Ito, Y., N. Azrolan, A. O'Connell, A. Walsh, and J. L. Breslow. 1990. Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice. Science. 249: 790-793.
    • (1990) Science , vol.249 , pp. 790-793
    • Ito, Y.1    Azrolan, N.2    O'Connell, A.3    Walsh, A.4    Breslow, J.L.5
  • 19
    • 0027989828 scopus 로고
    • Targeted disruption of the apolipoprotein C-III gene in mice results in hypertriglyceridemia and protection from postprandial hypertriglyceridemia
    • Maeda, N., H. Li, D. Lee, P. Oliver, S. H. Quarfordt, and J. Osada. 1994. Targeted disruption of the apolipoprotein C-III gene in mice results in hypertriglyceridemia and protection from postprandial hypertriglyceridemia. J. Biol. Chem. 269: 23610-23616.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23610-23616
    • Maeda, N.1    Li, H.2    Lee, D.3    Oliver, P.4    Quarfordt, S.H.5    Osada, J.6
  • 20
    • 0029920693 scopus 로고    scopus 로고
    • Lipoprotein lipase and lipolysis: Central roles in lipoprotein metabolism and atherogenesis
    • Goldberg, I. 1996. Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. J. Lipid Res. 37: 693-707.
    • (1996) J. Lipid Res. , vol.37 , pp. 693-707
    • Goldberg, I.1
  • 22
    • 0028817459 scopus 로고
    • Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase
    • Staels, B., N. Vu-Dac, V. A. Kosykh, R. Saladin, J. C. Fruchart, J. Dallongeville, and J. Auwerx. 1995. Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. J. Clin. Invest. 95: 705-712.
    • (1995) J. Clin. Invest. , vol.95 , pp. 705-712
    • Staels, B.1    Vu-Dac, N.2    Kosykh, V.A.3    Saladin, R.4    Fruchart, J.C.5    Dallongeville, J.6    Auwerx, J.7
  • 23
    • 0026577411 scopus 로고
    • Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat
    • Staels, B., A. Van Tol, T. Andreu, and J. Auwerx. 1992. Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat. Arterioscler. Thromb. 12: 286-294.
    • (1992) Arterioscler. Thromb. , vol.12 , pp. 286-294
    • Staels, B.1    Van Tol, A.2    Andreu, T.3    Auwerx, J.4
  • 24
    • 0025361083 scopus 로고
    • Apolipoprotein A-IV messenger ribonucleic acid abundance is regulated in a tissue-specific manner
    • Staels, B., A. van Tol, G. Verhoeven, and J. Auwerx. 1990. Apolipoprotein A-IV messenger ribonucleic acid abundance is regulated in a tissue-specific manner. Endocrinology. 126: 2153-2163.
    • (1990) Endocrinology , vol.126 , pp. 2153-2163
    • Staels, B.1    Van Tol, A.2    Verhoeven, G.3    Auwerx, J.4
  • 25
    • 0029131206 scopus 로고
    • Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II, and acyl-coenzyme a oxidase gene expression by fibrates and dietary fatty acids
    • Berthou, L., R. Saladin, P. Yaqoob, D. Branellec, P. Calder, J. C. Fruchart, P. Denefle, J. Auwerx, and B. Staels. 1995. Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II, and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids. Eur. J. Biochem. 232: 179-187.
    • (1995) Eur. J. Biochem. , vol.232 , pp. 179-187
    • Berthou, L.1    Saladin, R.2    Yaqoob, P.3    Branellec, D.4    Calder, P.5    Fruchart, J.C.6    Denefle, P.7    Auwerx, J.8    Staels, B.9
  • 26
    • 0029791412 scopus 로고    scopus 로고
    • PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
    • Schoonjans, K., J. Peinado-Onsurbe, A-M. Lefebvre, R. A. Heyman, M. Briggs, S. Deeb, B. Staels, and J. Auwerx. 1996. PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J. 15: 5336-5348.
    • (1996) EMBO J. , vol.15 , pp. 5336-5348
    • Schoonjans, K.1    Peinado-Onsurbe, J.2    Lefebvre, A.-M.3    Heyman, R.A.4    Briggs, M.5    Deeb, S.6    Staels, B.7    Auwerx, J.8
  • 27
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
    • Krey, G., O. Braissant, F. L'Horset, E. Kalkhoven, M. Perroud, M. G. Parker, and W. Wahli. 1997. Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol. Endocrinol. 11: 779-791.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 779-791
    • Krey, G.1    Braissant, O.2    L'Horset, F.3    Kalkhoven, E.4    Perroud, M.5    Parker, M.G.6    Wahli, W.7
  • 28
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
    • Forman, B. M., J. Chen, and R. M. Evans. 1997. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ. Proc. Natl. Acad. Sci. USA. 94: 4312-4317.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 29
    • 0031008797 scopus 로고    scopus 로고
    • Role of PPAR in the pharmacological regulation of lipoprotein metabolism by fibrates and thiazolidinediones
    • Staels, B., and J. Auwerx. 1997. Role of PPAR in the pharmacological regulation of lipoprotein metabolism by fibrates and thiazolidinediones. Curr. Pharmaceut. Des. 3: 1-14.
    • (1997) Curr. Pharmaceut. Des. , vol.3 , pp. 1-14
    • Staels, B.1    Auwerx, J.2
  • 30
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer, S. A., K. Umesono, D. J. Noonan, R. A. Heyman, and R. M. Evans. 1992. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature. 358: 771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 31
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimcrs
    • Keller, H., C. Dreyer, J. Medin, A. Mahfoudi, K. Ozato, and W. Wahli. 1993. Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimcrs. Proc. Natl. Acad. Sci. USA. 90: 2160-2164.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 33
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
    • Kliewer, S. A., J. M. Lenhard, T. M. Willson, I. Patel, D. C. Morris, and J. M. Lehman. 1995. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell. 83: 813-819.
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Willson, T.M.3    Patel, I.4    Morris, D.C.5    Lehman, J.M.6
  • 34
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
    • Lehmann, J. M., L. B. Moore, T. A. Smith-Oliver, W. O. Wilkison, T. M. Willson, and S. A. Kliewer. 1995. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J. Biol. Chem. 270: 12953-12956.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 35
    • 0028972025 scopus 로고
    • 15-Deoxy-Δ12,14 prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
    • Forman, B. M., P. Tontonoz, J. Chen, R. P. Brun, B. M. Spiegelman, and R. M. Evans. 1995. 15-Deoxy-Δ12,14 prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell. 83: 803-812.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 36
    • 0028998129 scopus 로고
    • Mode of action of peroxisome proliferators as hypolipidemic drugs, suppression of apolipoprotein C-III
    • Hertz, R., J. Bishara-Shieban, and J. Bar-Tana. 1995. Mode of action of peroxisome proliferators as hypolipidemic drugs, suppression of apolipoprotein C-III. J. Biol. Chem. 270: 13470-13475.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13470-13475
    • Hertz, R.1    Bishara-Shieban, J.2    Bar-Tana, J.3
  • 37
    • 0028036723 scopus 로고
    • Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element
    • Vu-Dac, N., K. Schoonjans, B. Laine, J. C. Fruchart, J. Auwerx, and B. Staels. 1994. Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element. J. Biol. Chem. 269: 31012-31018.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31012-31018
    • Vu-Dac, N.1    Schoonjans, K.2    Laine, B.3    Fruchart, J.C.4    Auwerx, J.5    Staels, B.6
  • 38
    • 0029119082 scopus 로고
    • Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor
    • Vu-Dac, N., K. Schoonjans, V. Kosykh, J. Dallongeville, J-C. Fruchart, B. Staels, and J. Auwerx. 1995. Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J. Clin. Invest. 96: 741-750.
    • (1995) J. Clin. Invest. , vol.96 , pp. 741-750
    • Vu-Dac, N.1    Schoonjans, K.2    Kosykh, V.3    Dallongeville, J.4    Fruchart, J.-C.5    Staels, B.6    Auwerx, J.7
  • 40
    • 0028997684 scopus 로고
    • Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee, S. S., T. Pineau, J. Drago, E. J. Lee, J. W. Owens, D. L. Kroetz, P. M. Fernandez-Salguero, H. Westphal, and F. J. Gonzalez. 1995. Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15: 3012-3022.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 42
    • 0024605609 scopus 로고
    • Induction of peroxisomal β-oxidation in 7800 Cl Morris hepatoma cells in steady state by fatty acids and fatty acid analogues
    • Spydevold, O., and J. Bremer. 1989. Induction of peroxisomal β-oxidation in 7800 Cl Morris hepatoma cells in steady state by fatty acids and fatty acid analogues. Biochim. Biophys. Acta. 1003: 72-79.
    • (1989) Biochim. Biophys. Acta. , vol.1003 , pp. 72-79
    • Spydevold, O.1    Bremer, J.2
  • 43
    • 0021260848 scopus 로고
    • Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochondria of rat liver by peroxisomal proliferators
    • Berge, R. K., T. Flatmark, and H. Osmudsen. 1984. Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochondria of rat liver by peroxisomal proliferators. Eur. J. Biochem. 141: 637-644.
    • (1984) Eur. J. Biochem. , vol.141 , pp. 637-644
    • Berge, R.K.1    Flatmark, T.2    Osmudsen, H.3
  • 44
    • 0027498292 scopus 로고
    • Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats
    • Willumsen, N., S. Hexeberg, J. Skorve, M. Lundquist, and R. K. Berge. 1993. Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats. J. Lipid Res. 34: 13-22.
    • (1993) J. Lipid Res. , vol.34 , pp. 13-22
    • Willumsen, N.1    Hexeberg, S.2    Skorve, J.3    Lundquist, M.4    Berge, R.K.5
  • 45
    • 0019798351 scopus 로고
    • The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA
    • Bremer, J. 1981. The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA. Biochim. Biophys. Acta. 665: 628-631.
    • (1981) Biochim. Biophys. Acta , vol.665 , pp. 628-631
    • Bremer, J.1
  • 46
    • 0016861431 scopus 로고
    • Intracellular localization of the 3-hydroxy-3-methylglutaryl CoA cycle enzymes in the liver
    • Clinkenbeard, K. D., W. D. Reed, R. A. Mooney, and M. D. Lane. 1975. Intracellular localization of the 3-hydroxy-3-methylglutaryl CoA cycle enzymes in the liver. J. Biol. Chem. 250: 3108-3116.
    • (1975) J. Biol. Chem. , vol.250 , pp. 3108-3116
    • Clinkenbeard, K.D.1    Reed, W.D.2    Mooney, R.A.3    Lane, M.D.4
  • 47
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, A.N.2
  • 48
    • 0023939138 scopus 로고
    • Transcriptional activation of the lipoprotein lipase and apolipoprotein E genes accompanies differentiation in some human macrophage-like cell lines
    • Auwerx, J., S. Deeb, J. D. Brunzell, R. Peng, and A. C. Chait. 1988. Transcriptional activation of the lipoprotein lipase and apolipoprotein E genes accompanies differentiation in some human macrophage-like cell lines. Biochemistry. 27: 2651-2655.
    • (1988) Biochemistry , vol.27 , pp. 2651-2655
    • Auwerx, J.1    Deeb, S.2    Brunzell, J.D.3    Peng, R.4    Chait, A.C.5
  • 49
    • 0018899345 scopus 로고
    • Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes
    • Cleveland, D. W., M. A. Lopata, R. J. McDonald, M. J. Cowan, W. J. Rutter, and M. W. Kirschner. 1980. Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes. Cell. 20: 95-105.
    • (1980) Cell , vol.20 , pp. 95-105
    • Cleveland, D.W.1    Lopata, M.A.2    McDonald, R.J.3    Cowan, M.J.4    Rutter, W.J.5    Kirschner, M.W.6
  • 50
    • 0020488029 scopus 로고
    • Cloning of cDNA sequences of hormone-regulated genes from MCF-7 human breast cancer cell line
    • Masiakowski, P., R. Breathnach, J. Bloch, F. Gannon, A. Krust, and P. Chambon. 1982. Cloning of cDNA sequences of hormone-regulated genes from MCF-7 human breast cancer cell line. Nucleic Acids Res. 10: 7895-7903.
    • (1982) Nucleic Acids Res. , vol.10 , pp. 7895-7903
    • Masiakowski, P.1    Breathnach, R.2    Bloch, J.3    Gannon, F.4    Krust, A.5    Chambon, P.6
  • 51
    • 0025778925 scopus 로고
    • 36B4 cDNA used as an estradiol-independent mRNA control is the ellNA for human acidic ribosomal phosphoprotein PO
    • Laborda, J. 1991. 36B4 cDNA used as an estradiol-independent mRNA control is the ellNA for human acidic ribosomal phosphoprotein PO. Nucleic Acids Res. 19: 3998.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 3998
    • Laborda, J.1
  • 52
    • 0027418315 scopus 로고
    • Cloning, sequencing, and expression of a cDNA encoding rat liver carnitine palmitoyltransferase i
    • Esser, V., C. H. Britton, B. C. Weis, D. W. Foster, and J. D. McGarry. 1993. Cloning, sequencing, and expression of a cDNA encoding rat liver carnitine palmitoyltransferase I. J. Biol. Chem. 268: 5817-5822.
    • (1993) J. Biol. Chem. , vol.268 , pp. 5817-5822
    • Esser, V.1    Britton, C.H.2    Weis, B.C.3    Foster, D.W.4    McGarry, J.D.5
  • 53
    • 0028329932 scopus 로고
    • Gene expression of enzymes regulating ketogenesis and fatty acid metabolism in regenerating rat liver
    • Asins, G., J. L. Rosa, D. Serra, G. Gil-Gomez, J. Ayté, R. Batrons, A. Tauler, and F. G. Hegardt. 1994. Gene expression of enzymes regulating ketogenesis and fatty acid metabolism in regenerating rat liver. Biochem. J. 299: 65-69.
    • (1994) Biochem. J. , vol.299 , pp. 65-69
    • Asins, G.1    Rosa, J.L.2    Serra, D.3    Gil-Gomez, G.4    Ayté, J.5    Batrons, R.6    Tauler, A.7    Hegardt, F.G.8
  • 55
    • 0025352338 scopus 로고
    • Rat mitochondrial and cytosolic 3-hydroxy-3-methyglutaryl CoA synthases are encoded by two different genes
    • Ayté, J., G. Gil-Gomez, D. Haro, P. F. Marrero, and F. G. Hegardt. 1990. Rat mitochondrial and cytosolic 3-hydroxy-3-methyglutaryl CoA synthases are encoded by two different genes. Proc. Natl. Acad. Sci. USA. 87: 3874-3878.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3874-3878
    • Ayté, J.1    Gil-Gomez, G.2    Haro, D.3    Marrero, P.F.4    Hegardt, F.G.5
  • 56
    • 0023649835 scopus 로고
    • CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements
    • Luckow, B., and G. Schütz. 1987. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res. 15: 5490.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 5490
    • Luckow, B.1    Schütz, G.2
  • 57
    • 0024299083 scopus 로고
    • The yeast UASg is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator
    • Webster, N., J. Jin, S. Green, M. Hollis, and P. Chambon. 1988. The yeast UASg is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator. Cell. 52: 169-178.
    • (1988) Cell , vol.52 , pp. 169-178
    • Webster, N.1    Jin, J.2    Green, S.3    Hollis, M.4    Chambon, P.5
  • 60
    • 0023711792 scopus 로고
    • Apolipoproteins and lipoproteins in human plasma: An overview
    • Brewer, B., R. Gregg, J. Hoeg, and S. Fojo. 1988. Apolipoproteins and lipoproteins in human plasma: an overview. Clin. Chem. 34: B4-B8.
    • (1988) Clin. Chem. , vol.34
    • Brewer, B.1    Gregg, R.2    Hoeg, J.3    Fojo, S.4
  • 61
    • 0031888994 scopus 로고    scopus 로고
    • Lipoprotein metabolism
    • Beisiegel, U. 1998. Lipoprotein metabolism. Eur. Heart J. 19: A20-A23.
    • (1998) Eur. Heart J. , vol.19
    • Beisiegel, U.1
  • 62
    • 0028069690 scopus 로고
    • Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E
    • de Silva, H. V., S. J. Lauer, J. Wang, W. S. Simonet, K. H. Weisgraber, R. W. Mahley, and J. M. Taylor. 1994. Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E. J. Biol. Chem. 269: 2324-2335.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2324-2335
    • De Silva, H.V.1    Lauer, S.J.2    Wang, J.3    Simonet, W.S.4    Weisgraber, K.H.5    Mahley, R.W.6    Taylor, J.M.7
  • 63
    • 0026443622 scopus 로고
    • Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles
    • Aalto-Setälä, K., E. A. Fisher, X. Chen, T. Chajek-Shaul, T. Hayek, R. Zechner, A. Walsh, R. Ramakrishnan, H. N. Ginsberg, and J. L. Breslow. 1992. Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles. J. Clin. Invest. 90: 1889-1900.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1889-1900
    • Aalto-Setälä, K.1    Fisher, E.A.2    Chen, X.3    Chajek-Shaul, T.4    Hayek, T.5    Zechner, R.6    Walsh, A.7    Ramakrishnan, R.8    Ginsberg, H.N.9    Breslow, J.L.10
  • 64
    • 0029018057 scopus 로고
    • Modulation of lipoprotein B binding to the ldl receptor by exogenous lipids and apolipoproteins CI, CII, CIII, and E
    • Clavey, V., S. Lestavel-Delattre, C. Copin, J. M. Bard, and J. C. Fruchart. 1995. Modulation of lipoprotein B binding to the LDL receptor by exogenous lipids and apolipoproteins CI, CII, CIII, and E. Arterioscler. Thromb. Vasc. Biol. 15: 963-971.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 963-971
    • Clavey, V.1    Lestavel-Delattre, S.2    Copin, C.3    Bard, J.M.4    Fruchart, J.C.5
  • 65
    • 0029791717 scopus 로고    scopus 로고
    • Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apo C-III transgenic mice
    • Aalto-Setälä, K., P. H. Weinstock, C. L. Bisgaier, L. Wu, J. D. Smith, and J. L. Breslow. 1996. Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apo C-III transgenic mice. J. Lipid Res. 37: 1802-1811.
    • (1996) J. Lipid Res. , vol.37 , pp. 1802-1811
    • Aalto-Setälä, K.1    Weinstock, P.H.2    Bisgaier, C.L.3    Wu, L.4    Smith, J.D.5    Breslow, J.L.6
  • 66
    • 0030911585 scopus 로고    scopus 로고
    • Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E
    • Ebara, T., R. Ramakrishnan, G. Steiner, and N. S. Shachter. 1997. Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E. J. Clin. Invest. 99: 2672-2681.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2672-2681
    • Ebara, T.1    Ramakrishnan, R.2    Steiner, G.3    Shachter, N.S.4
  • 67
    • 0018864840 scopus 로고
    • Regulation of hepatic fatty acid oxidation and ketone body production
    • McGarry, J. D., and D. W. Foster. 1980. Regulation of hepatic fatty acid oxidation and ketone body production. Annu. Rev. Biochem. 49: 395-420.
    • (1980) Annu. Rev. Biochem. , vol.49 , pp. 395-420
    • McGarry, J.D.1    Foster, D.W.2
  • 68
    • 0029874153 scopus 로고    scopus 로고
    • Long-term effect of tetradecylthioacetic acid: A study on plasma lipid profile and fatty acid composition and oxidation in different rat organs
    • Asiedu, D., L. Froyland, H. Vaagenes, O. Lie, A. Demoz, and R. K. Berge. 1996. Long-term effect of tetradecylthioacetic acid: a study on plasma lipid profile and fatty acid composition and oxidation in different rat organs. Biochim. Biophys. Acta. 1300: 86-96.
    • (1996) Biochim. Biophys. Acta , vol.1300 , pp. 86-96
    • Asiedu, D.1    Froyland, L.2    Vaagenes, H.3    Lie, O.4    Demoz, A.5    Berge, R.K.6
  • 70
    • 0031835267 scopus 로고    scopus 로고
    • Co-activators and co-repressors in the integration of transcriptional responses
    • Torchia, J., C. Glass, and M. Rosenfeld. 1998. Co-activators and co-repressors in the integration of transcriptional responses. Curr. Opin. Cell. Biol. 10: 373-383.
    • (1998) Curr. Opin. Cell. Biol. , vol.10 , pp. 373-383
    • Torchia, J.1    Glass, C.2    Rosenfeld, M.3
  • 71
    • 0031833450 scopus 로고    scopus 로고
    • The nuclear receptor ligand-binding domain: Structure and function
    • Moras, D. 1998. The nuclear receptor ligand-binding domain: structure and function. Curr. Opin. Cell. Biol. 10: 384-391.
    • (1998) Curr. Opin. Cell. Biol. , vol.10 , pp. 384-391
    • Moras, D.1
  • 72
    • 0031793335 scopus 로고    scopus 로고
    • Expression and hormonal regulation of coactivator and corepressor genes
    • Misiti, S., L. Schomburg, P. Yen, and W. Chin. 1998. Expression and hormonal regulation of coactivator and corepressor genes. Endocrinology. 139: 2493-2500.
    • (1998) Endocrinology , vol.139 , pp. 2493-2500
    • Misiti, S.1    Schomburg, L.2    Yen, P.3    Chin, W.4


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