Stereoselective effects of chiral clofibric acid analogs on rat peroxisome proliferator-activated receptor α (rPPARα) activation and peroxisomal fatty acid β-oxidation

Chirality

Volumn 9, Issue 1, 1997, Pages 37-47

  Rangwala, Shamina M ^a   O'Brien, Michelle L ^b   Tortorella, Vincenzo ^c   Longo, Antonio ^c   Loiodice, Fulvio ^c   Noonan, Daniel J ^b   Feller, Dennis R ^c,d  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF BARI   (Italy)

^d UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

absolute configuration assignment; CV 1 cells; fatty acyl CoA oxidase; H4IIEC3 cells; stereoselectivity; structure activity relationships

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; CELL NUCLEUS RECEPTOR; CLOFIBRIC ACID DERIVATIVE; PEROXISOME PROLIFERATOR;

ANIMAL CELL; ARTICLE; CHEMICAL MODIFICATION; CHIRALITY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG EFFECT; DRUG POTENCY; DRUG RECEPTOR BINDING; ENANTIOMER; FATTY ACID OXIDATION; HEPATOMA CELL; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ACYL-COA OXIDASE; ANIMALS; ANTILIPEMIC AGENTS; BINDING SITES; CLOFIBRIC ACID; FATTY ACIDS; LIVER NEOPLASMS, EXPERIMENTAL; MICROBODIES; OXIDATION-REDUCTION; OXIDOREDUCTASES; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0030890262     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1997)9:1<37::AID-CHIR8>3.0.CO;2-D     Document Type: Article

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