Structural Basis for Marburg Virus Neutralization by a Cross-Reactive Human Antibody

Cell

Volumn 160, Issue 5, 2015, Pages 904-912

  Hashiguchi, Takao ^a,b   Fusco, Marnie L ^a   Bornholdt, Zachary A ^a   Lee, Jeffrey E ^a,c   Flyak, Andrew I ^d   Matsuoka, Rei ^e   Kohda, Daisuke ^e   Yanagi, Yusuke ^b   Hammel, Michal ^f   Crowe, James E ^d,g   Saphire, Erica Ollmann ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF TORONTO   (Canada)

^d VANDERBILT UNIVERSITY   (United States)

^e KYUSHU UNIVERSITY   (Japan)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^g VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CROSS REACTING ANTIBODY; MUCIN; NEUTRALIZING ANTIBODY; VIRUS GLYCOPROTEIN; ANTIGEN ANTIBODY COMPLEX; ENVELOPE GLYCOPROTEIN, EBOLA VIRUS; GP-PROTEIN, MARBURG VIRUS; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

ALPHA HELIX; ANTIGEN RECOGNITION; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CROSS REACTION; CRYSTAL STRUCTURE; DISULFIDE BOND; EBOLA VIRUS; GLYCOSYLATION; HUMAN; HUMAN CELL; HYDROGEN BOND; MARBURG VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; VIRUS ENTRY; VIRUS NEUTRALIZATION; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; ANTIGEN ANTIBODY COMPLEX; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DROSOPHILA; EBOLAVIRUS; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; MARBURG HEMORRHAGIC FEVER; MARBURGVIRUS; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT;

EBOLA VIRUS; LAKE VICTORIA MARBURGVIRUS; MARBURGVIRUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGEN-ANTIBODY COMPLEX; CELL LINE; CROSS REACTIONS; CRYSTALLOGRAPHY, X-RAY; DROSOPHILA; EBOLAVIRUS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MARBURG VIRUS DISEASE; MARBURGVIRUS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUCINS; SEQUENCE ALIGNMENT; VIRAL ENVELOPE PROTEINS;

EID: 84923350941     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.01.041     Document Type: Article

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