The central structural feature of the membrane fusion protein subunit from the Ebola virus glycoprotein is a long triple-stranded coiled coil

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 11, 1998, Pages 6032-6036

  Weissenhorn, Winfried ^a   Calder, Lesley J ^b   Wharton, Stephen A ^b   Skehel, John J ^b   Wiley, Don C ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS GLYCOPROTEIN;

ALPHA HELIX; ARTICLE; CIRCULAR DICHROISM; EBOLA VIRUS; ELECTRON MICROSCOPY; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; CELL MEMBRANE; EBOLAVIRUS; GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SEQUENCE ANALYSIS; VIRAL ENVELOPE PROTEINS;

EBOLA VIRUS; FILOVIRIDAE; HUMAN IMMUNODEFICIENCY VIRUS 1; ORTHOMYXOVIRIDAE; RETROVIRIDAE;

EID: 0032568634     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.11.6032     Document Type: Article

References (50)

1. Bowen, E. T., Lloyd, G., Harris, W. J., Platt, G. S., Baskerville, A. & Vella, E. E. (1977) Lancet 1, 571-573.
2. Centers for Disease Control and Prevention (1995) Morbid. Mortal. Week. Rep. 44, 381-384.
3. Feldmann, H., Muhlberger, E., Randolf, A., Will, C., Kiley, M. P., Sanchez, A. & Klenk, H. D. (1992) Virus Res. 24, 1-19.
4. Sanchez, A., Kiley, M. P., Holloway, B. P. & Auperin, D. D. (1993) Virus Res. 29, 215-240.
5. Volchkov, V. E., Volchkova, V. A., Slenczka, W., Klenk, H.-D. & Feldmann, H. (1998) Virology, in press.
6. Volchkov, V. E., Feldmann, H., Volchkova, V. A. & Klenk, D.-D. (1998) Proc. Natl. Acad. Sci. USA 95, 5762-5767.
7. Volchkov, V. E., Becker, S., Volchkova, V. A., Ternovoj, V. A., Kotov, A. N., Netesov, S. V. & Klenk, H. D. (1995) Virology 214, 421-430.
8. Sanchez, A., Trappier, S. G., Mahy, B. W., Peters, C. J. & Nichol, S. T. (1996) Proc. Natl. Acad. Sci. USA 93, 3602-3607.
9. Yang, Z.-Y., Delgado, R., Xu, L., Todd, R. F., Nabel, E. G., Sanchez, A. & Nabel, G. J. (1998) Science 279, 1034-1037.
10. Schnittler, H. J., Mahner, F., Drenckhahn, D., Klenk, H. D. & Feldmann, H. (1993) J. Clin. Invest. 91, 1301-1309.
11. Becker, S., Spiess, M. & Klenk, H. D. (1995) J. Gen. Virol. 76, 393-399.
12. Gallaher, W. R., Ball, J. M., Garry, R. F., Griffin, M. C. & Montelaro, R. C. (1989) AIDS Res. Hum. Retroviruses 4, 431-440.
13. Chambers, P., Pringle, C. R. & Easton, A. J. (1990) J. Gen. Virol. 71, 3075-3080.
14. Gallaher, W. R. (1996) Cell 85, 477-478.
15. Bullough, P. A., Hughson, F. M., Skehel, J. J. & Wiley D. C. (1994) Nature (London) 371, 37-43.
16. Chan, D. C., Fass, D., Berger, J. M. & Kim, P. S. (1997) Cell 89, 263-273.
17. Weissenhorn, W., Dessen, A., Harrison, S. C., Skehel, J. J. & Wiley, D. C. (1997) Nature (London) 387, 426-430.
18. Tan, K., Liu, J., Wang, J., Shen, S. & Lu, M. (1997) Proc. Natl. Acad. Sci. USA 94, 12303-12308.
19. Fass, D., Harrison, S. C. & Kim, P. S. (1996) Nat. Struct. Biol. 3, 465-469.
20. Ruigrok, R. W., Aitken, A., Calder, L. J., Martin, S. R., Skehel, J. J., Wharton, S. A., Weis, W. & Wiley, D. C. (1988) J. Gen. Virol. 69, 2785-2795.
21. Chen, J., Wharton, S. A., Weissenhorn, W., Calder, L. J., Hughson, F. M., Skehel, J. J. & Wiley, D. C. (1995) Proc. Natl. Acad. Sci. USA 92, 12205-12209.
22. tk;2Weissenhorn, W., Wharton, S. A., Calder, L. J., Earl, P. L., Moss, B., Aliprandis, E., Skehel, J. J. & Wiley, D. C. (1996) EMBO J. 15, 1507-1514.
23. Weissenhorn, W., Calder, L. J., Dessen, A., Laue, T., Skehel, J. J. & Wiley, D. C. (1997b) Proc. Natl. Acad. Sci. USA 94, 6065-6069.
24. Harbury, P. B., Zhang, T., Kim, P. S. & Alber, T. (1993) Science 262, 1401-1407.
25. Brinkmann, U., Mattes, R. E. & Buckel, P. (1989) Gene 85, 109-114.
26. Laemmli, U. K. (1970) Nature (London) 227, 680-685.
27. O'Shea, E. K., Rutkowski, R. & Kim, P. S. (1989) Science 243, 538-542.
28. Wrigley, N. G., Brown, E. & Chillingworth, R. K. (1983) J. Microsc. (Oxford) 130, 225-232.
29. Wharton, S. A., Calder, L. J., Ruigrok, R. W., Skehel, J. J, Steinhauer, D. A. & Wiley, D. C. (1995) EMBO J. 14, 240-246.
30. Feldmann, H., Will, C., Schikore, M., Slenczka, W. & Klenk, H. D. (1991) Virology 182, 353-356.
31. Einfeld, D. & Hunter, E. (1988) Proc. Natl. Acad. Sci. USA 85, 8688-8692.
32. Blacklow, S. C., Lu, M. & Kim, P. S. (1995) Biochemistry 34, 14955-14962.
33. Lu, M., Blacklow, S. C. & Kim, P. S. (1995) Nat. Struct. Biol. 2, 1075-1082.
34. Fass, D. & Kim, P. S. (1995) Curr. Biol. 5, 1377-1383.
35. Wiley, D. C., Skehel, J. J. & Waterfield, M. (1977) Virology 79, 446-448.
36. Ruigrok, R. W., Martin, S. R., Wharton, S. A., Skehel, J. J., Bayley, P. M. & Wiley, D. C. (1986) Virology 155, 484-497.
37. Skehel, J. J., Bayley, P. M., Brown, E. B., Martin, S, R., Waterfield, M. D., White, J. M., Wilson, I. A. & Wiley, D. C. (1982) Proc. Natl. Acad. Sci. USA 79, 968-972.
38. Sattentau, Q. & Moore, J. P. (1991) J. Exp. Med. 174, 407-415.
39. Jones, P., Korte, T. & Blumenthal, R. (1998) J. Biol. Chem. 273, 404-409.
40. Carr, C. M., Chaudhry, C. & Kim, P. S. (1997) Proc. Natl. Acad. Sci. USA 94, 14306-14313.
41. Volchkov, V. E., Blinov, V. M. & Netesov, S. V. (1992) FEBS Lett. 305, 181-184.
42. Cianciolo, G. J., Copeland, T. D., Oroszlan, S. & Snyderman, R. (1985) Science 230, 453-455.
43. Wilson, I. A., Skehel, J. J. & Wiley, D. C. (1981) Nature (London) 289, 366-373.
44. Carr, C. M. & Kim, P. S. (1993) Cell 73, 823-832.
45. Hanson, P. I., Roth, R., Morisaki, H., Jahn, R. & Heuser, J. E. (1997) Cell 90, 523-535.
46. Sollner, T., Bennett, M. K., Whiteheart, S. W., Scheller, R. H. & Rothman, J. E. (1993) Cell 75, 409-418.
47. Hayashi, T., McMahon, H., Yamasaki, S., Binz, T., Hata, Y., Sudhof, T. C. & Niemann, H. (1994) EMBO J. 13, 5051-5061.
48. Kee, Y., Lin, R. C., Hsu, S. C. & Scheller, R. H. (1995) Neuron 14, 991-998.
49. Weimbs, T., Low, S. H., Chapin, S. J., Mostov, K. E., Bucher, p. & Hofmann, K. (1997) Proc. Natl. Acad. Sci. USA 94, 3046-3051.
50. Weber, T., Zemelman, B. V., McNew, J. A., Westermann, B. Gmachl, M., Parlati, F., Söllner, T. H. & Rothman, J. E. (1998) Cell 92, 759-772.