메뉴 건너뛰기




Volumn 109, Issue 44, 2012, Pages 18030-18035

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

Author keywords

Passive immunization; Therapy

Indexed keywords

MB 003; MONOCLONAL ANTIBODY; PALIVIZUMAB; UNCLASSIFIED DRUG;

EID: 84868149422     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213709109     Document Type: Article
Times cited : (318)

References (41)
  • 2
    • 34548512432 scopus 로고    scopus 로고
    • Filoviridae: Marburg and Ebola viruses
    • eds Knipe DM, Howley PM (Lippincott Williams & Wilkins, Philadelphia), 4th Ed
    • Sanchez A, et al. (2001) Filoviridae Marburg and Ebola viruses. Fields Virology, eds Knipe DM, Howley PM (Lippincott Williams & Wilkins, Philadelphia), 4th Ed.
    • (2001) Fields Virology
    • Sanchez, A.1
  • 3
    • 33644653708 scopus 로고    scopus 로고
    • Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers
    • Warfield KL, et al. (2006) Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers. PLoS Pathog 2(1):e1.
    • (2006) PLoS Pathog , vol.2 , Issue.1
    • Warfield, K.L.1
  • 4
    • 33846500073 scopus 로고    scopus 로고
    • Effective post-exposure treatment of Ebola infection
    • Feldmann H, et al. (2007) Effective post-exposure treatment of Ebola infection. PLoS Pathog 3(1):e2.
    • (2007) PLoS Pathog , vol.3 , Issue.1
    • Feldmann, H.1
  • 5
    • 77952680862 scopus 로고    scopus 로고
    • Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: A proof-of-concept study
    • Geisbert TW, et al. (2010) Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: A proof-of-concept study. Lancet 375(9729):1896-1905.
    • (2010) Lancet , vol.375 , Issue.9729 , pp. 1896-1905
    • Geisbert, T.W.1
  • 6
    • 79551575923 scopus 로고    scopus 로고
    • Advances in the assessment and control of the effector functions of therapeutic antibodies
    • Jiang XR, et al. (2011) Advances in the assessment and control of the effector functions of therapeutic antibodies. Nat Rev Drug Discov 10(2):101-111.
    • (2011) Nat Rev Drug Discov , vol.10 , Issue.2 , pp. 101-111
    • Jiang, X.R.1
  • 7
    • 0029032565 scopus 로고
    • Return to the past: The case for antibody-based therapies in infectious diseases
    • Casadevall A, Scharff MD (1995) Return to the past: The case for antibody-based therapies in infectious diseases. Clin Infect Dis 21(1):150-161.
    • (1995) Clin Infect Dis , vol.21 , Issue.1 , pp. 150-161
    • Casadevall, A.1    Scharff, M.D.2
  • 8
    • 0034051215 scopus 로고    scopus 로고
    • Preventing infectious disease with passive immunization
    • Zeitlin L, Cone RA, Moench TR, Whaley KJ (2000) Preventing infectious disease with passive immunization. Microbes Infect 2(6):701-708.
    • (2000) Microbes Infect , vol.2 , Issue.6 , pp. 701-708
    • Zeitlin, L.1    Cone, R.A.2    Moench, T.R.3    Whaley, K.J.4
  • 9
    • 0033062193 scopus 로고    scopus 로고
    • Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients
    • International Scientific and Technical Committee
    • Mupapa K, et al.; International Scientific and Technical Committee (1999) Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients. J Infect Dis 179(Suppl 1):S18-S23.
    • (1999) J Infect Dis , vol.179 , Issue.SUPPL. 1
    • Mupapa, K.1
  • 10
    • 0029440828 scopus 로고
    • Development and study of the properties of immunoglobulin against Ebola fever
    • Russian
    • Borisevich IV, et al. (1995) Development and study of the properties of immunoglobulin against Ebola fever. Vopr Virusol, 40(6):270-273, Russian.
    • (1995) Vopr Virusol , vol.40 , Issue.6 , pp. 270-273
    • Borisevich, I.V.1
  • 11
    • 0032993241 scopus 로고    scopus 로고
    • Preparation and use of hyperimmune serum for prophylaxis and therapy of Ebola virus infections
    • Kudoyarova-Zubavichene NM, Sergeyev NN, Chepurnov AA, Netesov SV (1999) Preparation and use of hyperimmune serum for prophylaxis and therapy of Ebola virus infections. J Infect Dis 179(Suppl 1):S218-S223.
    • (1999) J Infect Dis , vol.179 , Issue.SUPPL. 1
    • Kudoyarova-Zubavichene, N.M.1    Sergeyev, N.N.2    Chepurnov, A.A.3    Netesov, S.V.4
  • 13
    • 0033066490 scopus 로고    scopus 로고
    • Evaluation of immune globulin and recombinant interferon- alpha2b for treatment of experimental Ebola virus infections
    • Jahrling PBGT, et al. (1999) Evaluation of immune globulin and recombinant interferon- alpha2b for treatment of experimental Ebola virus infections. J Infect Dis 179 (Suppl 1):S224-S234.
    • (1999) J Infect Dis , vol.179 , Issue.SUPPL. 1
    • Jahrling, P.B.G.T.1
  • 14
    • 0034051595 scopus 로고    scopus 로고
    • Epitopes involved in antibody-mediated protection from Ebola virus
    • Wilson JA, et al. (2000) Epitopes involved in antibody-mediated protection from Ebola virus. Science 287(5458):1664-1666.
    • (2000) Science , vol.287 , Issue.5458 , pp. 1664-1666
    • Wilson, J.A.1
  • 15
    • 0036100307 scopus 로고    scopus 로고
    • Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody
    • Parren PWHI, Geisbert TW, Maruyama T, Jahrling PB, Burton DR (2002) Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody. J Virol 76(12):6408-6412.
    • (2002) J Virol , vol.76 , Issue.12 , pp. 6408-6412
    • Parren, P.W.H.I.1    Geisbert, T.W.2    Maruyama, T.3    Jahrling, P.B.4    Burton, D.R.5
  • 16
    • 0035222608 scopus 로고    scopus 로고
    • The antiviral activity of antibodies in vitro and in vivo
    • Parren PW, Burton DR (2001) The antiviral activity of antibodies in vitro and in vivo. Adv Immunol 77:195-262.
    • (2001) Adv Immunol , vol.77 , pp. 195-262
    • Parren, P.W.1    Burton, D.R.2
  • 17
    • 38449092660 scopus 로고    scopus 로고
    • Ebola hemorrhagic fever: Evaluation of passive immunotherapy in nonhuman primates
    • Jahrling PB, Geisbert JB, Swearengen JR, Larsen T, Geisbert TW (2007) Ebola hemorrhagic fever: Evaluation of passive immunotherapy in nonhuman primates. J Infect Dis 196(Suppl 2):S400-S403.
    • (2007) J Infect Dis , vol.196 , Issue.SUPPL. 2
    • Jahrling, P.B.1    Geisbert, J.B.2    Swearengen, J.R.3    Larsen, T.4    Geisbert, T.W.5
  • 18
    • 84860456246 scopus 로고    scopus 로고
    • Protective efficacy of neutralizing monoclonal antibodies in a nonhuman primate model of Ebola hemorrhagic fever
    • Marzi A, et al. (2012) Protective efficacy of neutralizing monoclonal antibodies in a nonhuman primate model of Ebola hemorrhagic fever. PLoS ONE 7(4):e36192.
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Marzi, A.1
  • 19
    • 33846490649 scopus 로고    scopus 로고
    • Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys
    • Oswald WB, et al. (2007) Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys. PLoS Pathog 3(1):e9.
    • (2007) PLoS Pathog , vol.3 , Issue.1
    • Oswald, W.B.1
  • 20
    • 84859462127 scopus 로고    scopus 로고
    • Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease
    • Dye JM, et al. (2012) Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease. Proc Natl Acad Sci USA 109(13):5034-5039.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.13 , pp. 5034-5039
    • Dye, J.M.1
  • 21
    • 84862525229 scopus 로고    scopus 로고
    • Successful treatment of Ebola virus-infected cynomolgus macaques with monoclonal antibodies
    • Qiu X, et al. (2012) Successful treatment of Ebola virus-infected cynomolgus macaques with monoclonal antibodies. Sci Transl Med 4(138):138ra81.
    • (2012) Sci Transl Med , vol.4 , Issue.138
    • Qiu, X.1
  • 22
    • 0035148629 scopus 로고    scopus 로고
    • Ebola virus glycoprotein: Proteolytic processing, acylation, cell tropism, and detection of neutralizing antibodies
    • Ito H, Watanabe S, Takada A, Kawaoka Y (2001) Ebola virus glycoprotein: Proteolytic processing, acylation, cell tropism, and detection of neutralizing antibodies. J Virol 75 (3):1576-1580.
    • (2001) J Virol , vol.75 , Issue.3 , pp. 1576-1580
    • Ito, H.1    Watanabe, S.2    Takada, A.3    Kawaoka, Y.4
  • 23
    • 84862908635 scopus 로고    scopus 로고
    • Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant
    • Zeitlin L, et al. (2011) Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant. Proc Natl Acad Sci USA 108(51): 20690-20694.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.51 , pp. 20690-20694
    • Zeitlin, L.1
  • 24
    • 33749536223 scopus 로고    scopus 로고
    • Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors
    • Giritch A, et al. (2006) Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors. Proc Natl Acad Sci USA 103(40):14701- 14706.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.40 , pp. 14701-14706
    • Giritch, A.1
  • 25
    • 77953980755 scopus 로고    scopus 로고
    • Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems
    • Pogue GP, et al. (2010) Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems. Plant Biotechnol J 8(5):638-654.
    • (2010) Plant Biotechnol J , vol.8 , Issue.5 , pp. 638-654
    • Pogue, G.P.1
  • 26
    • 41749105290 scopus 로고    scopus 로고
    • Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure
    • Strasser R, et al. (2008) Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure. Plant Biotechnol J 6(4):392-402.
    • (2008) Plant Biotechnol J , vol.6 , Issue.4 , pp. 392-402
    • Strasser, R.1
  • 27
    • 65249161767 scopus 로고    scopus 로고
    • Disease modeling for Ebola and Marburg viruses
    • Bente D, Gren J, Strong JE, Feldmann H (2009) Disease modeling for Ebola and Marburg viruses. Dis Model Mech 2(1-2):12-17.
    • (2009) Dis Model Mech , vol.2 , Issue.1-2 , pp. 12-17
    • Bente, D.1    Gren, J.2    Strong, J.E.3    Feldmann, H.4
  • 28
    • 84868159913 scopus 로고    scopus 로고
    • Antibody-mediated Fcγ receptor-based mechanisms of HIV inhibition: Recent findings and new vaccination strategies
    • Holl V, Peressin M, Moog C (2009) Antibody-mediated Fcγ receptor-based mechanisms of HIV inhibition: Recent findings and new vaccination strategies. Viruses 1(3): 1265-1294.
    • (2009) Viruses , vol.1 , Issue.3 , pp. 1265-1294
    • Holl, V.1    Peressin, M.2    Moog, C.3
  • 29
    • 77950957371 scopus 로고    scopus 로고
    • Antibodies: Beyond neutralization
    • Bubnoff A (2010) Antibodies: Beyond neutralization. IAVI Rep 14(1):8-12.
    • (2010) IAVI Rep , vol.14 , Issue.1 , pp. 8-12
    • Bubnoff, A.1
  • 30
    • 22144488793 scopus 로고    scopus 로고
    • Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection
    • Warfield KL, et al. (2005) Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection. J Immunol 175(2):1184-1191.
    • (2005) J Immunol , vol.175 , Issue.2 , pp. 1184-1191
    • Warfield, K.L.1
  • 31
    • 80052444401 scopus 로고    scopus 로고
    • CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates
    • Sullivan NJ, et al. (2011) CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates. Nat Med 17(9):1128-1131.
    • (2011) Nat Med , vol.17 , Issue.9 , pp. 1128-1131
    • Sullivan, N.J.1
  • 32
    • 0030611643 scopus 로고    scopus 로고
    • FcgammaRIIIa-158V/F polymorphism influences the binding of IgG by natural k cell FcgammaRIIIa, independently of the FcgammaRIIIa-48L/R/H phenotype
    • Koene HR, et al. (1997) FcgammaRIIIa-158V/F polymorphism influences the binding of IgG by natural k cell FcgammaRIIIa, independently of the FcgammaRIIIa-48L/R/H phenotype. Blood 90(3):1109-1114.
    • (1997) Blood , vol.90 , Issue.3 , pp. 1109-1114
    • Koene, H.R.1
  • 33
    • 80053211245 scopus 로고    scopus 로고
    • Rituximab infusion induces NK activation in lymphoma patients with the high-affinity CD16 polymorphism
    • Veeramani S, et al. (2011) Rituximab infusion induces NK activation in lymphoma patients with the high-affinity CD16 polymorphism. Blood 118(12):3347-3349.
    • (2011) Blood , vol.118 , Issue.12 , pp. 3347-3349
    • Veeramani, S.1
  • 34
    • 85172051787 scopus 로고    scopus 로고
    • Influence of Fc gamma-receptor polymorphisms on efficacy of antibody-mediated lymphocyte depletion in rhesus macaques
    • abstr
    • Finstad SL, Zhang G (2010) Influence of Fc gamma-receptor polymorphisms on efficacy of antibody-mediated lymphocyte depletion in rhesus macaques. J Med Primatol, 39(4):279-280 (abstr).
    • (2010) J Med Primatol , vol.39 , Issue.4 , pp. 279-280
    • Finstad, S.L.1    Zhang, G.2
  • 35
    • 79958228219 scopus 로고    scopus 로고
    • Characterization and allelic polymorphisms of rhesus macaque (Macaca mulatta) IgG Fc receptor genes
    • Nguyen DC, Scinicariello F, Attanasio R (2011) Characterization and allelic polymorphisms of rhesus macaque (Macaca mulatta) IgG Fc receptor genes. Immunogenetics 63(6):351-362.
    • (2011) Immunogenetics , vol.63 , Issue.6 , pp. 351-362
    • Nguyen, D.C.1    Scinicariello, F.2    Attanasio, R.3
  • 37
    • 0029976177 scopus 로고    scopus 로고
    • The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing
    • Sanchez A, Trappier SG, Mahy BW, Peters CJ, Nichol ST (1996) The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing. Proc Natl Acad Sci USA 93(8):3602-3607.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.8 , pp. 3602-3607
    • Sanchez, A.1    Trappier, S.G.2    Mahy, B.W.3    Peters, C.J.4    Nichol, S.T.5
  • 38
    • 0027985431 scopus 로고
    • Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
    • Burton DR, et al. (1994) Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 266(5187):1024-1027.
    • (1994) Science , vol.266 , Issue.5187 , pp. 1024-1027
    • Burton, D.R.1
  • 39
    • 0042739176 scopus 로고    scopus 로고
    • Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates
    • Sullivan NJ, et al. (2003) Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates. Nature 424(6949):681-684.
    • (2003) Nature , vol.424 , Issue.6949 , pp. 681-684
    • Sullivan, N.J.1
  • 40
    • 0030571019 scopus 로고    scopus 로고
    • A rapid high-resolution highperformance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles
    • Guile GR, Rudd PM, Wing DR, Prime SB, Dwek RA (1996) A rapid high-resolution highperformance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles. Anal Biochem 240(2):210-226.
    • (1996) Anal Biochem , vol.240 , Issue.2 , pp. 210-226
    • Guile, G.R.1    Rudd, P.M.2    Wing, D.R.3    Prime, S.B.4    Dwek, R.A.5
  • 41
    • 0003633755 scopus 로고
    • Committee On Care and Use of Laboratory Animals (Natl Inst Health, Bethesda), DHHS Pub No (NIH)
    • Committee On Care and Use of Laboratory Animals (1985) Guide for the Care and Use of Laboratory Animals (Natl Inst Health, Bethesda), DHHS Pub No (NIH) 85-23
    • (1985) Guide for the Care and Use of Laboratory Animals , pp. 85-23


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.