Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

Nature Communications

Volumn 6, Issue , 2015, Pages

  Liou, Geou Yarh ^a   Döppler, Heike ^a   Braun, Ursula B ^b   Panayiotou, Richard ^a   Scotti Buzhardt, Michele ^a   Radisky, Derek C ^a   Crawford, Howard C ^a   Fields, Alan P ^a   Murray, Nicole R ^a   Wang, Q Jane ^c   Leitges, Michael ^b   Storz, Peter ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF OSLO   (Norway)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

K RAS PROTEIN; MUCIN 1; PROTEIN KINASE D; PROTEIN KINASE D1; PROTEIN KINASE D2; PROTEIN KINASE D3; RAS PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; KRAS2 PROTEIN, MOUSE; NOTCH RECEPTOR; PROTEIN KINASE C; PROTEIN P21;

CYTOLOGY; ENZYME ACTIVITY; GROWTH REGULATOR; MUTATION; PHENOTYPE; SIGNAL;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PROGNOSIS; CELL DEDIFFERENTIATION; CELL TRANSDIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PANCREAS ADENOMA; PANCREAS CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; C57BL MOUSE; CARCINOMA IN SITU; CELL TRANSFORMATION; DISEASE COURSE; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PANCREAS TUMOR; PANCREATIC DUCT; PATHOLOGY; PHENOTYPE;

ANIMALIA;

ACINAR CELLS; ANIMALS; CARCINOMA IN SITU; CELL TRANSFORMATION, NEOPLASTIC; CELLULAR REPROGRAMMING; DISEASE PROGRESSION; MICE, INBRED C57BL; PANCREATIC DUCTS; PANCREATIC NEOPLASMS; PHENOTYPE; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTORS, NOTCH; TRANSFORMING GROWTH FACTOR ALPHA; UP-REGULATION;

EID: 84923323788     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7200     Document Type: Article

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