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Volumn 12, Issue 3, 2007, Pages 266-279

Concomitant Pancreatic Activation of KrasG12D and Tgfa Results in Cystic Papillary Neoplasms Reminiscent of Human IPMN

Author keywords

CELLCYCLE

Indexed keywords

ELASTASE; EPIDERMAL GROWTH FACTOR RECEPTOR; MUCIN 1; MUCIN 2; MUCIN 5AC; PROTEIN P48; STAT3 PROTEIN; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 34548205213     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2007.08.002     Document Type: Article
Times cited : (132)

References (50)
  • 1
    • 18644383374 scopus 로고    scopus 로고
    • The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: Differential expression of MUC1 and MUC2 supports the existence of two separate pathways of carcinogenesis
    • Adsay N.V., Merati K., Andea A., Sarkar F., Hruban R.H., Wilentz R.E., Goggins M., Iocobuzio-Donahue C., Longnecker D.S., and Klimstra D.S. The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: Differential expression of MUC1 and MUC2 supports the existence of two separate pathways of carcinogenesis. Mod. Pathol. 15 (2002) 1087-1095
    • (2002) Mod. Pathol. , vol.15 , pp. 1087-1095
    • Adsay, N.V.1    Merati, K.2    Andea, A.3    Sarkar, F.4    Hruban, R.H.5    Wilentz, R.E.6    Goggins, M.7    Iocobuzio-Donahue, C.8    Longnecker, D.S.9    Klimstra, D.S.10
  • 7
    • 0026020115 scopus 로고
    • Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer
    • Barton C.M., Hall P.A., Hughes C.M., Gullick W.J., and Lemoine N.R. Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer. J. Pathol. 163 (1991) 111-116
    • (1991) J. Pathol. , vol.163 , pp. 111-116
    • Barton, C.M.1    Hall, P.A.2    Hughes, C.M.3    Gullick, W.J.4    Lemoine, N.R.5
  • 8
    • 0036110390 scopus 로고    scopus 로고
    • Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma
    • Biankin A.V., Biankin S.A., Kench J.G., Morey A.L., Lee C.S., Head D.R., Eckstein R.P., Hugh T.B., Henshall S.M., and Sutherland R.L. Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma. Gut 50 (2002) 861-868
    • (2002) Gut , vol.50 , pp. 861-868
    • Biankin, A.V.1    Biankin, S.A.2    Kench, J.G.3    Morey, A.L.4    Lee, C.S.5    Head, D.R.6    Eckstein, R.P.7    Hugh, T.B.8    Henshall, S.M.9    Sutherland, R.L.10
  • 9
    • 4344710457 scopus 로고    scopus 로고
    • Pancreatic intraepithelial neoplasia in association with intraductal papillary mucinous neoplasms of the pancreas: Implications for disease progression and recurrence
    • Biankin A.V., Kench J.G., Biankin S.A., Lee C.S., Morey A.L., Dijkman F.P., Coleman M.J., Sutherland R.L., and Henshall S.M. Pancreatic intraepithelial neoplasia in association with intraductal papillary mucinous neoplasms of the pancreas: Implications for disease progression and recurrence. Am. J. Surg. Pathol. 28 (2004) 1184-1192
    • (2004) Am. J. Surg. Pathol. , vol.28 , pp. 1184-1192
    • Biankin, A.V.1    Kench, J.G.2    Biankin, S.A.3    Lee, C.S.4    Morey, A.L.5    Dijkman, F.P.6    Coleman, M.J.7    Sutherland, R.L.8    Henshall, S.M.9
  • 15
    • 0038405066 scopus 로고    scopus 로고
    • Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice
    • Grippo P.J., Nowlin P.S., Demeure M.J., Longnecker D.S., and Sandgren E.P. Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice. Cancer Res. 63 (2003) 2016-2019
    • (2003) Cancer Res. , vol.63 , pp. 2016-2019
    • Grippo, P.J.1    Nowlin, P.S.2    Demeure, M.J.3    Longnecker, D.S.4    Sandgren, E.P.5
  • 16
    • 0036340074 scopus 로고    scopus 로고
    • Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
    • Gu G., Dubauskaite J., and Melton D.A. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 129 (2002) 2447-2457
    • (2002) Development , vol.129 , pp. 2447-2457
    • Gu, G.1    Dubauskaite, J.2    Melton, D.A.3
  • 24
    • 0036730427 scopus 로고    scopus 로고
    • The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
    • Kawaguchi Y., Cooper B., Gannon M., Ray M., MacDonald R.J., and Wright C.V. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat. Genet. 32 (2002) 128-134
    • (2002) Nat. Genet. , vol.32 , pp. 128-134
    • Kawaguchi, Y.1    Cooper, B.2    Gannon, M.3    Ray, M.4    MacDonald, R.J.5    Wright, C.V.6
  • 25
    • 4544301890 scopus 로고    scopus 로고
    • Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: A review of 418 cases and a classification proposal
    • Kosmahl M., Pauser U., Peters K., Sipos B., Luttges J., Kremer B., and Kloppel G. Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: A review of 418 cases and a classification proposal. Virchows Arch. 445 (2004) 168-178
    • (2004) Virchows Arch. , vol.445 , pp. 168-178
    • Kosmahl, M.1    Pauser, U.2    Peters, K.3    Sipos, B.4    Luttges, J.5    Kremer, B.6    Kloppel, G.7
  • 26
    • 0034962469 scopus 로고    scopus 로고
    • The immunohistochemical mucin expression pattern distinguishes different types of intraductal papillary mucinous neoplasms of the pancreas and determines their relationship to mucinous noncystic carcinoma and ductal adenocarcinoma
    • Luttges J., Zamboni G., Longnecker D., and Kloppel G. The immunohistochemical mucin expression pattern distinguishes different types of intraductal papillary mucinous neoplasms of the pancreas and determines their relationship to mucinous noncystic carcinoma and ductal adenocarcinoma. Am. J. Surg. Pathol. 25 (2001) 942-948
    • (2001) Am. J. Surg. Pathol. , vol.25 , pp. 942-948
    • Luttges, J.1    Zamboni, G.2    Longnecker, D.3    Kloppel, G.4
  • 31
    • 34247390587 scopus 로고    scopus 로고
    • Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina
    • Nakhai H., Sel S., Favor J., Mendoza-Torres L., Paulsen F., Duncker G.I., and Schmid R.M. Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina. Development 134 (2007) 1151-1160
    • (2007) Development , vol.134 , pp. 1151-1160
    • Nakhai, H.1    Sel, S.2    Favor, J.3    Mendoza-Torres, L.4    Paulsen, F.5    Duncker, G.I.6    Schmid, R.M.7
  • 32
    • 33747882404 scopus 로고    scopus 로고
    • Sonic hedgehog is an early developmental marker of intraductal papillary mucinous neoplasms: Clinical implications of mRNA levels in pancreatic juice
    • Ohuchida K., Mizumoto K., Fujita H., Yamaguchi H., Konomi H., Nagai E., Yamaguchi K., Tsuneyoshi M., and Tanaka M. Sonic hedgehog is an early developmental marker of intraductal papillary mucinous neoplasms: Clinical implications of mRNA levels in pancreatic juice. J. Pathol. 210 (2006) 42-48
    • (2006) J. Pathol. , vol.210 , pp. 42-48
    • Ohuchida, K.1    Mizumoto, K.2    Fujita, H.3    Yamaguchi, H.4    Konomi, H.5    Nagai, E.6    Yamaguchi, K.7    Tsuneyoshi, M.8    Tanaka, M.9
  • 35
    • 16444378654 scopus 로고    scopus 로고
    • Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells
    • Prasad N.B., Biankin A.V., Fukushima N., Maitra A., Dhara S., Elkahloun A.G., Hruban R.H., Goggins M., and Leach S.D. Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells. Cancer Res. 65 (2005) 1619-1626
    • (2005) Cancer Res. , vol.65 , pp. 1619-1626
    • Prasad, N.B.1    Biankin, A.V.2    Fukushima, N.3    Maitra, A.4    Dhara, S.5    Elkahloun, A.G.6    Hruban, R.H.7    Goggins, M.8    Leach, S.D.9
  • 36
    • 0025297086 scopus 로고
    • Overexpression of TGF alpha in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • Sandgren E.P., Luetteke N.C., Palmiter R.D., Brinster R.L., and Lee D.C. Overexpression of TGF alpha in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 61 (1990) 1121-1135
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.C.5
  • 39
    • 19344376176 scopus 로고    scopus 로고
    • Chromosomal instability in mouse metastatic pancreatic cancer-it's Kras and Tp53 after all
    • Siveke J.T., and Schmid R.M. Chromosomal instability in mouse metastatic pancreatic cancer-it's Kras and Tp53 after all. Cancer Cell 7 (2005) 405-407
    • (2005) Cancer Cell , vol.7 , pp. 405-407
    • Siveke, J.T.1    Schmid, R.M.2
  • 44
    • 0036243735 scopus 로고    scopus 로고
    • p16 and p53 gene alterations and accumulations in the malignant evolution of intraductal papillary-mucinous tumors of the pancreas
    • Wada K. p16 and p53 gene alterations and accumulations in the malignant evolution of intraductal papillary-mucinous tumors of the pancreas. J. Hepatobiliary Pancreat. Surg. 9 (2002) 76-85
    • (2002) J. Hepatobiliary Pancreat. Surg. , vol.9 , pp. 76-85
    • Wada, K.1
  • 46
    • 0031787342 scopus 로고    scopus 로고
    • Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice
    • Wagner M., Luhrs H., Kloppel G., Adler G., and Schmid R.M. Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice. Gastroenterology 115 (1998) 1254-1262
    • (1998) Gastroenterology , vol.115 , pp. 1254-1262
    • Wagner, M.1    Luhrs, H.2    Kloppel, G.3    Adler, G.4    Schmid, R.M.5
  • 49
    • 0036838840 scopus 로고    scopus 로고
    • Characterisation of oestrogen receptor, progesterone receptor, trefoil factor 1, and epidermal growth factor and its receptor in pancreatic cystic neoplasms and pancreatic ductal adenocarcinoma
    • Yeh T.S., Jan Y.Y., Chiu C.T., Ho Y.B., Chen T.C., Lee K.F., Chan K.M., Hsu J.C., Hwang T.L., and Chen M.F. Characterisation of oestrogen receptor, progesterone receptor, trefoil factor 1, and epidermal growth factor and its receptor in pancreatic cystic neoplasms and pancreatic ductal adenocarcinoma. Gut 51 (2002) 712-716
    • (2002) Gut , vol.51 , pp. 712-716
    • Yeh, T.S.1    Jan, Y.Y.2    Chiu, C.T.3    Ho, Y.B.4    Chen, T.C.5    Lee, K.F.6    Chan, K.M.7    Hsu, J.C.8    Hwang, T.L.9    Chen, M.F.10
  • 50
    • 29144444453 scopus 로고    scopus 로고
    • Significance of cellular distribution of ezrin in pancreatic cystic neoplasms and ductal adenocarcinoma
    • Yeh T.S., Tseng J.H., Liu N.J., Chen T.C., Jan Y.Y., and Chen M.F. Significance of cellular distribution of ezrin in pancreatic cystic neoplasms and ductal adenocarcinoma. Arch. Surg. 140 (2005) 1184-1190
    • (2005) Arch. Surg. , vol.140 , pp. 1184-1190
    • Yeh, T.S.1    Tseng, J.H.2    Liu, N.J.3    Chen, T.C.4    Jan, Y.Y.5    Chen, M.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.