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Volumn 97, Issue 9, 2014, Pages 5437-5447

Peroxisome proliferator-activated receptor γ1 and γ2 isoforms alter lipogenic gene networks in goat mammary epithelial cells to different extents

Author keywords

Fatty acid metabolism; Gene network; Lactation; Mammary gland; Nuclear receptor

Indexed keywords

BOVIDAE; CAPRA HIRCUS;

EID: 84923317050     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2013-7863     Document Type: Article
Times cited : (36)

References (58)
  • 1
    • 84880416695 scopus 로고    scopus 로고
    • Milk fat content and DGAT1 genotype determine lipid composition of the milk fat globule membrane
    • Argov-Argaman N., Mida K., Cohen B.-C., Visker M., Hettinga K. Milk fat content and DGAT1 genotype determine lipid composition of the milk fat globule membrane. PLoS ONE 2013, 8:e68707.
    • (2013) PLoS ONE , vol.8
    • Argov-Argaman, N.1    Mida, K.2    Cohen, B.-C.3    Visker, M.4    Hettinga, K.5
  • 3
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J., Moller D.E. The mechanisms of action of PPARs. Annu. Rev. Med. 2002, 53:409-435.
    • (2002) Annu. Rev. Med. , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 4
    • 84878333643 scopus 로고    scopus 로고
    • Functional role of PPARs in ruminants: Potential targets for fine-tuning metabolism during growth and lactation
    • Bionaz M., Chen S., Khan M.J., Loor J.J. Functional role of PPARs in ruminants: Potential targets for fine-tuning metabolism during growth and lactation. PPAR Res. 2013, 2013:684159.
    • (2013) PPAR Res. , vol.2013 , pp. 684159
    • Bionaz, M.1    Chen, S.2    Khan, M.J.3    Loor, J.J.4
  • 5
    • 52249089184 scopus 로고    scopus 로고
    • Gene networks driving bovine milk fat synthesis during the lactation cycle
    • Bionaz M., Loor J. Gene networks driving bovine milk fat synthesis during the lactation cycle. BMC Genomics 2008, 9:366.
    • (2008) BMC Genomics , vol.9 , pp. 366
    • Bionaz, M.1    Loor, J.2
  • 6
    • 34347230863 scopus 로고    scopus 로고
    • Identification of reference genes for quantitative real-time PCR in the bovine mammary gland during the lactation cycle
    • Bionaz M., Loor J.J. Identification of reference genes for quantitative real-time PCR in the bovine mammary gland during the lactation cycle. Physiol. Genomics 2007, 29:312-319.
    • (2007) Physiol. Genomics , vol.29 , pp. 312-319
    • Bionaz, M.1    Loor, J.J.2
  • 7
    • 44449113267 scopus 로고    scopus 로고
    • ACSL1, AGPAT6, FABP3, LPIN1, and SLC27A6 are the most abundant isoforms in bovine mammary tissue and their expression is affected by stage of lactation
    • Bionaz M., Loor J.J. ACSL1, AGPAT6, FABP3, LPIN1, and SLC27A6 are the most abundant isoforms in bovine mammary tissue and their expression is affected by stage of lactation. J. Nutr. 2008, 138:1019-1024.
    • (2008) J. Nutr. , vol.138 , pp. 1019-1024
    • Bionaz, M.1    Loor, J.J.2
  • 8
    • 66449119706 scopus 로고    scopus 로고
    • The PPARγ2 A/B-domain plays a gene-specific role in transactivation and cofactor recruitment
    • Bugge A., Grøntved L., Aagaard M.M., Borup R., Mandrup S. The PPARγ2 A/B-domain plays a gene-specific role in transactivation and cofactor recruitment. Mol. Endocrinol. 2009, 23:794-808.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 794-808
    • Bugge, A.1    Grøntved, L.2    Aagaard, M.M.3    Borup, R.4    Mandrup, S.5
  • 13
    • 10044271037 scopus 로고    scopus 로고
    • SREBP transcription factors: Master regulators of lipid homeostasis
    • Eberlé D., Hegarty B., Bossard P., Ferré P., Foufelle F. SREBP transcription factors: Master regulators of lipid homeostasis. Biochimie 2004, 86:839-848.
    • (2004) Biochimie , vol.86 , pp. 839-848
    • Eberlé, D.1    Hegarty, B.2    Bossard, P.3    Ferré, P.4    Foufelle, F.5
  • 15
    • 72449154616 scopus 로고    scopus 로고
    • Impact of the Pro12Ala polymorphism of the PPAR-gamma 2 gene on metabolic and clinical characteristics in the Palestinian type 2 diabetic patients
    • Ereqat S., Nasereddin A., Azmi K., Abdeen Z., Amin R. Impact of the Pro12Ala polymorphism of the PPAR-gamma 2 gene on metabolic and clinical characteristics in the Palestinian type 2 diabetic patients. PPAR Res. 2009, 2009:874126.
    • (2009) PPAR Res. , vol.2009 , pp. 874126
    • Ereqat, S.1    Nasereddin, A.2    Azmi, K.3    Abdeen, Z.4    Amin, R.5
  • 18
    • 62549085567 scopus 로고    scopus 로고
    • Liver X receptor modulators: Effects on lipid metabolism and potential use in the treatment of atherosclerosis
    • Fiévet C., Staels B. Liver X receptor modulators: Effects on lipid metabolism and potential use in the treatment of atherosclerosis. Biochem. Pharmacol. 2009, 77:1316-1327.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 1316-1327
    • Fiévet, C.1    Staels, B.2
  • 21
    • 70349292693 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents
    • Kadegowda A.K.G., Bionaz M., Piperova L.S., Erdman R.A., Loor J.J. Peroxisome proliferator-activated receptor-γ activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents. J. Dairy Sci. 2009, 92:4276-4289.
    • (2009) J. Dairy Sci. , vol.92 , pp. 4276-4289
    • Kadegowda, A.K.G.1    Bionaz, M.2    Piperova, L.S.3    Erdman, R.A.4    Loor, J.J.5
  • 22
    • 2642546601 scopus 로고    scopus 로고
    • Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein in the regulation of adipogenesis
    • Kast-Woelbern H.R., Dana S.L., Cesario R.M., Sun L., de Grandpre L.Y., Brooks M.E., Osburn D.L., Reifel-Miller A., Klausing K., Leibowitz M.D. Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein in the regulation of adipogenesis. J. Biol. Chem. 2004, 279:23908-23915.
    • (2004) J. Biol. Chem. , vol.279 , pp. 23908-23915
    • Kast-Woelbern, H.R.1    Dana, S.L.2    Cesario, R.M.3    Sun, L.4    de Grandpre, L.Y.5    Brooks, M.E.6    Osburn, D.L.7    Reifel-Miller, A.8    Klausing, K.9    Leibowitz, M.D.10
  • 24
    • 0036319490 scopus 로고    scopus 로고
    • Rosiglitazone, a peroxisome proliferator-activated receptor γ, inhibits the Jun NH2-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury
    • Khandoudi N., Delerive P., Berrebi-Bertrand I., Buckingham R.E., Staels B., Bril A. Rosiglitazone, a peroxisome proliferator-activated receptor γ, inhibits the Jun NH2-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury. Diabetes 2002, 51:1507-1514.
    • (2002) Diabetes , vol.51 , pp. 1507-1514
    • Khandoudi, N.1    Delerive, P.2    Berrebi-Bertrand, I.3    Buckingham, R.E.4    Staels, B.5    Bril, A.6
  • 26
    • 60349084474 scopus 로고    scopus 로고
    • Activation of PPARα and PPARγ reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1
    • König B., Koch A., Spielmann J., Hilgenfeld C., Hirche F., Stangl G.I., Eder K. Activation of PPARα and PPARγ reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1. Eur. J. Pharmacol. 2009, 605:23-30.
    • (2009) Eur. J. Pharmacol. , vol.605 , pp. 23-30
    • König, B.1    Koch, A.2    Spielmann, J.3    Hilgenfeld, C.4    Hirche, F.5    Stangl, G.I.6    Eder, K.7
  • 27
    • 0037144604 scopus 로고    scopus 로고
    • Insulin and sterol-regulatory element-binding protein-1c (SREBP-1C) regulation of gene expression in 3T3-L1 adipocytes
    • Le Lay S., Lefrère I., Trautwein C., Dugail I., Krief S. Insulin and sterol-regulatory element-binding protein-1c (SREBP-1C) regulation of gene expression in 3T3-L1 adipocytes. J. Biol. Chem. 2002, 277:35625-35634.
    • (2002) J. Biol. Chem. , vol.277 , pp. 35625-35634
    • Le Lay, S.1    Lefrère, I.2    Trautwein, C.3    Dugail, I.4    Krief, S.5
  • 29
    • 84876719500 scopus 로고    scopus 로고
    • MiR-27a suppresses triglyceride accumulation and affects gene mRNA expression associated with fat metabolism in dairy goat mammary gland epithelial cells
    • Lin X., Luo J., Zhang L., Wang W., Shi H., Zhu J. MiR-27a suppresses triglyceride accumulation and affects gene mRNA expression associated with fat metabolism in dairy goat mammary gland epithelial cells. Gene 2013, 521:15-23.
    • (2013) Gene , vol.521 , pp. 15-23
    • Lin, X.1    Luo, J.2    Zhang, L.3    Wang, W.4    Shi, H.5    Zhu, J.6
  • 31
    • 84862537960 scopus 로고    scopus 로고
    • Transcriptional regulation of lipid synthesis in bovine mammary epithelial cells by sterol regulatory element binding protein-1
    • Ma L., Corl B.A. Transcriptional regulation of lipid synthesis in bovine mammary epithelial cells by sterol regulatory element binding protein-1. J. Dairy Sci. 2012, 95:3743-3755.
    • (2012) J. Dairy Sci. , vol.95 , pp. 3743-3755
    • Ma, L.1    Corl, B.A.2
  • 33
    • 77956839449 scopus 로고    scopus 로고
    • Activation of liver X receptor (LXR) enhances de novo fatty acid synthesis in bovine mammary epithelial cells
    • McFadden J.W., Corl B.A. Activation of liver X receptor (LXR) enhances de novo fatty acid synthesis in bovine mammary epithelial cells. J. Dairy Sci. 2010, 93:4651-4658.
    • (2010) J. Dairy Sci. , vol.93 , pp. 4651-4658
    • McFadden, J.W.1    Corl, B.A.2
  • 35
    • 84876464064 scopus 로고    scopus 로고
    • Yin yang 1 and adipogenic gene network expression in longissimus muscle of beef cattle in response to nutritional management
    • Moisá S.J., Shike D.W., Meteer W.T., Keisler D., Faulkner D.B., Loor J.J. Yin yang 1 and adipogenic gene network expression in longissimus muscle of beef cattle in response to nutritional management. Gene Regul. Syst. Bio. 2013, 7:71-83.
    • (2013) Gene Regul. Syst. Bio. , vol.7 , pp. 71-83
    • Moisá, S.J.1    Shike, D.W.2    Meteer, W.T.3    Keisler, D.4    Faulkner, D.B.5    Loor, J.J.6
  • 37
    • 0029077405 scopus 로고
    • The regulation of stearoyl-COA desaturase (SCD)
    • Ntambi J.M. The regulation of stearoyl-COA desaturase (SCD). Prog. Lipid Res. 1995, 34:139-150.
    • (1995) Prog. Lipid Res. , vol.34 , pp. 139-150
    • Ntambi, J.M.1
  • 38
    • 3042750635 scopus 로고    scopus 로고
    • Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated secretion of milk-lipid droplets
    • Ogg S.L., Weldon A.K., Dobbie L., Smith A.J.H., Mather I.H. Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated secretion of milk-lipid droplets. Proc. Natl. Acad. Sci. USA 2004, 101:10084-10089.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10084-10089
    • Ogg, S.L.1    Weldon, A.K.2    Dobbie, L.3    Smith, A.J.H.4    Mather, I.H.5
  • 39
    • 84871615896 scopus 로고    scopus 로고
    • Regulation of lipid synthesis by liver X receptor alpha and sterol regulatory element-binding protein 1 in mammary epithelial cells
    • Oppi-Williams C., Suagee J.K., Corl B.A. Regulation of lipid synthesis by liver X receptor alpha and sterol regulatory element-binding protein 1 in mammary epithelial cells. J. Dairy Sci. 2013, 96:112-121.
    • (2013) J. Dairy Sci. , vol.96 , pp. 112-121
    • Oppi-Williams, C.1    Suagee, J.K.2    Corl, B.A.3
  • 40
    • 13644266892 scopus 로고    scopus 로고
    • Comparative analysis of gene sequence of goat CSN1S1F and N alleles and characterization of CSN1S1 transcript variants in mammary gland
    • Ramunno L., Cosenza G., Rando A., Pauciullo A., Illario R., Gallo D., Di Berardino D., Masina P. Comparative analysis of gene sequence of goat CSN1S1F and N alleles and characterization of CSN1S1 transcript variants in mammary gland. Gene 2005, 345:289-299.
    • (2005) Gene , vol.345 , pp. 289-299
    • Ramunno, L.1    Cosenza, G.2    Rando, A.3    Pauciullo, A.4    Illario, R.5    Gallo, D.6    Di Berardino, D.7    Masina, P.8
  • 41
    • 0036007025 scopus 로고    scopus 로고
    • PPAR gamma knockdown by engineered transcription factors: Exogenous PPARγ2 but not PPARγ1 reactivates adipogenesis
    • Ren D., Collingwood T.N., Rebar E.J., Wolffe A.P., Camp H.S. PPAR gamma knockdown by engineered transcription factors: Exogenous PPARγ2 but not PPARγ1 reactivates adipogenesis. Genes Dev. 2002, 16:27-32.
    • (2002) Genes Dev. , vol.16 , pp. 27-32
    • Ren, D.1    Collingwood, T.N.2    Rebar, E.J.3    Wolffe, A.P.4    Camp, H.S.5
  • 43
    • 34249720160 scopus 로고    scopus 로고
    • SREBP-1c mediates the retinoid-dependent increase in fatty acid synthase promoter activity in HepG2
    • Roder K., Zhang L., Schweizer M. SREBP-1c mediates the retinoid-dependent increase in fatty acid synthase promoter activity in HepG2. FEBS Lett. 2007, 581:2715-2720.
    • (2007) FEBS Lett. , vol.581 , pp. 2715-2720
    • Roder, K.1    Zhang, L.2    Schweizer, M.3
  • 44
    • 0035851187 scopus 로고    scopus 로고
    • PPARG: A nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen E.D., Spiegelman B.M. PPARG: A nuclear regulator of metabolism, differentiation, and cell growth. J. Biol. Chem. 2001, 276:37731-37734.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 47
    • 84888023638 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-Y stimulates the synthesis of monounsaturated fatty acids in dairy goat mammary epithelial cells via the control of stearoyl-coenzyme A desaturase
    • Shi H.B., Luo J., Yao D.W., Zhu J.J., Xu H.F., Shi H.P., Loor J.J. Peroxisome proliferator-activated receptor-Y stimulates the synthesis of monounsaturated fatty acids in dairy goat mammary epithelial cells via the control of stearoyl-coenzyme A desaturase. J. Dairy Sci. 2013, 96:7844-7853.
    • (2013) J. Dairy Sci. , vol.96 , pp. 7844-7853
    • Shi, H.B.1    Luo, J.2    Yao, D.W.3    Zhu, J.J.4    Xu, H.F.5    Shi, H.P.6    Loor, J.J.7
  • 48
    • 84877299620 scopus 로고    scopus 로고
    • PPARγ regulates genes involved in triacylglycerol synthesis and secretion in mammary gland epithelial cells of dairy goats
    • Shi H.B., Luo J., Zhu J.J., Li J., Sun Y.T., Lin X.Z., Zhang L.P., Yao D.W., Shi H.P. PPARγ regulates genes involved in triacylglycerol synthesis and secretion in mammary gland epithelial cells of dairy goats. PPAR Res. 2013, 2013:310948.
    • (2013) PPAR Res. , vol.2013 , pp. 310948
    • Shi, H.B.1    Luo, J.2    Zhu, J.J.3    Li, J.4    Sun, Y.T.5    Lin, X.Z.6    Zhang, L.P.7    Yao, D.W.8    Shi, H.P.9
  • 49
    • 0034804783 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Transcriptional regulators of lipid synthetic genes
    • Shimano H. Sterol regulatory element-binding proteins (SREBPs): Transcriptional regulators of lipid synthetic genes. Prog. Lipid Res. 2001, 40:439-452.
    • (2001) Prog. Lipid Res. , vol.40 , pp. 439-452
    • Shimano, H.1
  • 50
    • 0031590465 scopus 로고    scopus 로고
    • Characterisation of bovine peroxisome proliferator-activated receptors γ1 and γ2: Genetic mapping and differential expression of the two isoforms
    • Sundvold H., Brzozowska A., Lien S. Characterisation of bovine peroxisome proliferator-activated receptors γ1 and γ2: Genetic mapping and differential expression of the two isoforms. Biochem. Biophys. Res. Commun. 1997, 239:857-861.
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 857-861
    • Sundvold, H.1    Brzozowska, A.2    Lien, S.3
  • 51
  • 54
    • 35548930322 scopus 로고    scopus 로고
    • Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors
    • Villacorta L., Garcia-Barrio M., Chen Y. Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors. Curr. Atheroscler. Rep. 2007, 9:230-237.
    • (2007) Curr. Atheroscler. Rep. , vol.9 , pp. 230-237
    • Villacorta, L.1    Garcia-Barrio, M.2    Chen, Y.3
  • 55
    • 34547618810 scopus 로고    scopus 로고
    • Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk
    • Wan Y., Saghatelian A., Chong L.-W., Zhang C.-L., Cravatt B.F., Evans R.M. Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk. Genes Dev. 2007, 21:1895-1908.
    • (2007) Genes Dev. , vol.21 , pp. 1895-1908
    • Wan, Y.1    Saghatelian, A.2    Chong, L.-W.3    Zhang, C.-L.4    Cravatt, B.F.5    Evans, R.M.6
  • 56
    • 84863883694 scopus 로고    scopus 로고
    • Goat liver X receptor α, molecular cloning, functional characterization and regulating fatty acid synthesis in epithelial cells of goat mammary glands
    • Wang W., Luo J., Zhong Y., Lin X., Shi H., Zhu J., Li J., Sun Y., Zhao W. Goat liver X receptor α, molecular cloning, functional characterization and regulating fatty acid synthesis in epithelial cells of goat mammary glands. Gene 2012, 505:114-120.
    • (2012) Gene , vol.505 , pp. 114-120
    • Wang, W.1    Luo, J.2    Zhong, Y.3    Lin, X.4    Shi, H.5    Zhu, J.6    Li, J.7    Sun, Y.8    Zhao, W.9
  • 57
    • 78049455926 scopus 로고    scopus 로고
    • Characterization and culture of isolated primary dairy goat mammary gland epithelial cells
    • Wang Z., Luo J., Wang W., Zhao W., Lin X. Characterization and culture of isolated primary dairy goat mammary gland epithelial cells. Sheng Wu Gong Cheng Xue Bao 2010, 26:1123-1127.
    • (2010) Sheng Wu Gong Cheng Xue Bao , vol.26 , pp. 1123-1127
    • Wang, Z.1    Luo, J.2    Wang, W.3    Zhao, W.4    Lin, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.