Milk Fat Content and DGAT1 Genotype Determine Lipid Composition of the Milk Fat Globule Membrane

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Argov Argaman, Nurit ^a   Mida, Kfir ^a   Cohen, Bat Chen ^a   Visker, Marleen ^b   Hettinga, Kasper ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL ACYLTRANSFERASE 1; MILK FAT; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; SPHINGOMYELIN;

ARTICLE; BIOPROCESS; BREAST EPITHELIUM; CORRELATION ANALYSIS; ENZYME POLYMORPHISM; FAT CONTENT; FOOD ANALYSIS; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID COMPOSITION; LIPOGENESIS; MILK; NONHUMAN; PHENOTYPE; PROTEIN INTERACTION;

ANIMALS; BIOLOGICAL MARKERS; BREEDING; CATTLE; DAIRYING; DIACYLGLYCEROL O-ACYLTRANSFERASE; FEMALE; GLYCOLIPIDS; GLYCOPROTEINS; MEMBRANE LIPIDS; MILK; PHOSPHOLIPIDS; POLYMORPHISM, GENETIC; TRIGLYCERIDES;

EID: 84880416695     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068707     Document Type: Article

References (38)

1. Dillard CJ, German JB, (2004) Saturated fat: What dietary intake? Am J Clin Nutr 80: 550-559.
2. Huth PJ, Park KM, (2012) Influence of dairy product and milk fat consumption on cardiovascular disease risk: a review of the evidence. Adv Nutr 3: 266-285.
3. Mozaffarian D, Micha R, Wallace S, (2010) Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Med 7: e1000252.
4. Burgess JW, Neville TAM, Rouillard P, Harder Z, Beanlands DS, et al. (2005) Phosphatidylinositol increases HDL-C levels in humans. J Lipid Res 46: 350-355.
5. Argov N, Lemay D, German J, (2008) Milk fat globule structure & function; nanoscience comes to milk production. Trends Food Sci Technol 9: 617-623.
6. Dillehay DL, Webb SK, Schmelz EM, Merrill AH, (1994) Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice. J Nutr 124: 615-620.
7. Ocke MC, Larranaga N, Grioni S, van den Berg SW, Ferrari P, et al. (2009) Energy intake and sources of energy intake in the European Prospective Investigation into Cancer and Nutrition. Eur J Clin Nutr 63: S3-15.
8. Jensen RG, (2002) The composition of bovine milk lipids: January 1995 to December 2000. J Dairy Sci 85: 295-350.
9. Dewettinck K, Rombaut R, Thienpont N, Le T, Messens K, et al. (2007) Nutritional and technological aspects of milk fat globule membrane material. Int Dairy J 18: 436-457.
10. Bitman J, Wood D, (1990) Changes in milk fat phospholipids during lactation. J Dairy Sci 73: 1208-1216.
11. Mather IH, Keenan TW, (1998) Origin and secretion of milk lipids. J Mammary Gland Biol Neoplasia 3: 259-273.
12. Michalski M-C, Ollivon M, Briard V, Leconte N, Lopez C, (2004) Native fat globules of different sizes selected from raw milk: thermal and structural behavior. Chem Phys Lipids 132: 247-261.
13. Lopez C, Briard-Bion V, Menard O, Rousseau F, Pradel P, et al. (2008) Phospholipid, sphingolipid, and fatty acid compositions of the milk fat globule membrane are modified by diet. J Agric Food Chem 56: 5226-5236.
14. Mesilati-Stahy R, Mida K, Argov-Argaman N, (2011) Size-dependent lipid content of bovine milk fat globule and membrane phospholipids. J Agric Food Chem 59: 7427-7435.
15. Heck JML, van Valenberg HJF, Dijkstra J, van Hooijdonk ACM, (2009) Seasonal variation in the Dutch bovine raw milk composition. J Dairy Sci 92: 4745-4755.
16. Grisart B, Farnir F, Karim L, Cambisano N, Kim J, et al. (2004) Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition. Proc Natl Acad Sci 24: 2398-2403.
17. Schennink A, Stoop W, Visker M, Heck J, Bovenhuis H, et al. (2007) DGAT1 underlies large genetic variation in milk-fat composition of dairy cows. Anim Genet 38: 467-473.
18. Wiking L, Nielsen JH, Bavius AK, Edvardsson A, Svennersten-Sjaunja K, (2006) Impact of milking frequencies on the level of free fatty acids in milk, fat globule size, and fatty acid composition. J Dairy Sci 89: 1004-1009.
19. Menard O, Ahmed S, Rousseau F, Briard-Bion V, Gaucheron F, et al. (2010) Buffalo vs. cow milk fat globules: Size distribution, zeta-potential, compositions in total fatty acids and in polar lipids from the milk fat globule membrane. Food Chem 120: 544-551.
20. Argov-Argaman N, Mbogori T, Sabastian C, Shamay A, Mabjeesh SJ, (2012) Hyperinsulinemic clamp modulates milk fat globule lipid composition in goats. J Dairy Sci 95: 5776-5787.
21. Mesilati-Stahy R, Malka H, Argov-Argaman N, (2012) Association of plasma insulin concentration to fatty acid distribution between milk fat and membrane synthesis. J Dairy Sci 95: 1767-1775.
22. Lopez C, Briard-Bion V, Ménard O, Beaucher E, Rousseau F, et al. (2010) Fat globules selected from whole milk according to their size: Different compositions and structure of the biomembrane, revealing sphingomyelin-rich domains. Food Chem 125: 355-368.
23. Cases S, Smith S, Zhang Y, Myers H, Lear S, et al. (1980) Identification of a gene encoding and acyl CoA: diacylglycerol acyltransferase, a key enzyme in triacylglycerol snyrhsis. Proc Natl Acad Sci 27: 13018-13023.
24. Stoop WM, Bovenhuis H, van Arendonk JA, (2007) Genetic parameters for milk urea nitrogen in relation to milk production traits. J Dairy Sci 90: 1981-1986.
25. Folch J, Lees M, Sloane Stanley GH, (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226: 497-509.
26. Gilmour A, Gogel B, Cullis B, Thompson R (2006) ASReml user guide release 2.0. Hempstead, UK: VSN International Ltd.
27. Wilmink J, (1987) Adjustment of test-day milk, fat and protein yield for age, season and stage of lactation. Livestock Prod Sci 16: 335-348.
28. Michalski M, Gassi J, Famelart M, Leconte N, Camier B, et al. (2003) The size of the native milk fat globules affects physico-chemical and sensory properties of Camembert cheese. Lait 83: 131-134.
29. Couvreur S, Hurtaud C, Marnet PG, Faverdin P, Peyraud JL, (2007) Composition of milk fat from cows selected for milk fat globule size and offered either fresh pasture or a corn silage-based diet. J Dairy Sci 90: 392-403.
30. Stals HK, Top W, Declercq PE, (1994) Regulation of triacylglycerol synthesis in permeabilized rat hepatocytes. Role of fatty acid concentration and diacylglycerol acyltransferase. FEBS Lett 343: 99-9102.
31. Jackowski S, Wang J, Baburina I, (2000) Activity of the phosphatidylcholine biosynthetic pathway modulates the distribution of fatty acids into glycerolipids in proliferating cells. Biochim Biophys Acta 1483: 301-315.
32. Bengato C, Igal R, (2003) Overexpression of diacylglycerol acyltransferase-1 reduces phospholipid synthesis, proliferation, and invasiveness in simian virus 40-transformed human lung fibroblasts. J Biol Chem 278: 52203-52211.
33. Keenan T, Huang C, (1972) Membrane of mammary gland VI: Protein and lipid composition of golgi apparatus and rough endoplasmic reticulum from bovine mammary gland. J Dairy Sci 55: 1586-1596.
34. Ghosal D, Shappell NW, Keenan TW, (1994) Endoplasmic reticulum lumenal proteins of rat mammary gland. Potential involvement in lipid droplet assembly during lactation. Biochim Biophys Acta 1200: 175-181.
35. Cohen FS, Akabas MH, Zimmerberg J, Finkelstein A, (1984) Parameters affecting the fusion of unilamellar phospholipid vesicles with planar bilayer membranes. J Cell Biol 98: 1054-1062.
36. Golovastov V, Zolov S, Nesmeyanova M, (2002) Study of interaction of export initiation domain of Escherichia coli mature alkaline phosphatase with membrane phospholipids during secretion. Biokhimiya 67: 1182-1190.
37. Mikhaleva NI, Golovastov VV, Zolov SN, Bogdanov MV, Dowhan W, et al. (2001) Depletion of phosphatidylethanolamine affects secretion of Escherichia coli alkaline phosphatase and its transcriptional expression. FEBS Lett 493: 85-90.
38. Hamilton RL, Fielding PE, (1989) Nascent very low density lipoproteins from rat hepatocytic Golgi fractions are enriched in phosphatidylethanolamine. Biochem Biophys Res Commun 160: 162-173.