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Volumn 93, Issue 10, 2010, Pages 4651-4658

Activation of liver X receptor (LXR) enhances de novo fatty acid synthesis in bovine mammary epithelial cells

Author keywords

Bovine mammary epithelial cell; Fat synthesis; Liver X receptor (LXR); Sterol regulatory element binding protein (SREBP)

Indexed keywords

FATTY ACID; LIVER X RECEPTOR; ORPHAN NUCLEAR RECEPTOR;

EID: 77956839449     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2010-3202     Document Type: Article
Times cited : (49)

References (32)
  • 1
    • 52249089184 scopus 로고    scopus 로고
    • Gene networks driving bovine milk fat synthesis during the lactation cycle
    • Bionaz M., Loor J.J. Gene networks driving bovine milk fat synthesis during the lactation cycle. BMC Genomics 2008, 9:366.
    • (2008) BMC Genomics , vol.9 , pp. 366
    • Bionaz, M.1    Loor, J.J.2
  • 2
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown M.S., Goldstein J.L. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 1997, 89:331-340.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 4
    • 0033599028 scopus 로고    scopus 로고
    • Transport-dependent proteolysis of SREBP: Relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi
    • DeBose-Boyd R.A., Brown M.S., Li W.P., Nohturfft A., Goldstein J.L., Espenshade P.J. Transport-dependent proteolysis of SREBP: Relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi. Cell 1999, 99:703-712.
    • (1999) Cell , vol.99 , pp. 703-712
    • DeBose-Boyd, R.A.1    Brown, M.S.2    Li, W.P.3    Nohturfft, A.4    Goldstein, J.L.5    Espenshade, P.J.6
  • 5
    • 0035852770 scopus 로고    scopus 로고
    • Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands
    • DeBose-Boyd R.A., Ou J.F., Goldstein J.L., Brown M.S. Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands. Proc. Natl. Acad. Sci. USA 2001, 98:1477-1482.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1477-1482
    • DeBose-Boyd, R.A.1    Ou, J.F.2    Goldstein, J.L.3    Brown, M.S.4
  • 6
    • 0346849699 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor β/δ agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells
    • Dressel U., Allen T.L., Pippal J.B., Rohde P.R., Lau P., Muscat G.E. The peroxisome proliferator-activated receptor β/δ agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells. Mol. Endocrinol. 2003, 17:2477-2493.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 2477-2493
    • Dressel, U.1    Allen, T.L.2    Pippal, J.B.3    Rohde, P.R.4    Lau, P.5    Muscat, G.E.6
  • 7
    • 2142751644 scopus 로고    scopus 로고
    • Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis
    • Engelking L.J., Kuriyama H., Hammer R.E., Horton J.D., Brown M.S., Goldstein J.L., Liang G. Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis. J. Clin. Invest. 2004, 113:1168-1175.
    • (2004) J. Clin. Invest. , vol.113 , pp. 1168-1175
    • Engelking, L.J.1    Kuriyama, H.2    Hammer, R.E.3    Horton, J.D.4    Brown, M.S.5    Goldstein, J.L.6    Liang, G.7
  • 8
    • 0030904931 scopus 로고    scopus 로고
    • Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene
    • Ericsson J., Jackson S.M., Kim J.B., Spiegelman B.M., Edwards P.A. Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene. J. Biol. Chem. 1997, 272:7298-7305.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7298-7305
    • Ericsson, J.1    Jackson, S.M.2    Kim, J.B.3    Spiegelman, B.M.4    Edwards, P.A.5
  • 9
    • 57049120625 scopus 로고    scopus 로고
    • Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue
    • Farke C., Meyer H.H., Bruckmaier R.M., Albrecht C. Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue. J. Dairy Res. 2008, 75:406-414.
    • (2008) J. Dairy Res. , vol.75 , pp. 406-414
    • Farke, C.1    Meyer, H.H.2    Bruckmaier, R.M.3    Albrecht, C.4
  • 11
    • 33749471630 scopus 로고    scopus 로고
    • SREBP1 and thyroid hormone responsive Spot 14 (S14) are involved in the regulation of bovine mammary lipid synthesis during diet-induced milk fat depression and treatment with CLA
    • Harvatine K.J., Bauman D.E. SREBP1 and thyroid hormone responsive Spot 14 (S14) are involved in the regulation of bovine mammary lipid synthesis during diet-induced milk fat depression and treatment with CLA. J. Nutr. 2006, 136:2468-2474.
    • (2006) J. Nutr. , vol.136 , pp. 2468-2474
    • Harvatine, K.J.1    Bauman, D.E.2
  • 12
    • 57649121280 scopus 로고    scopus 로고
    • Expression of PPAR and LXR nuclear hormone receptor families are not modified during milk fat depression induced by diet or treatment with trans-10, cis-12 conjugated linoleic acid (CLA)
    • (Abstr.)
    • Harvatine K.J., Bauman D.E. Expression of PPAR and LXR nuclear hormone receptor families are not modified during milk fat depression induced by diet or treatment with trans-10, cis-12 conjugated linoleic acid (CLA). J. Dairy Sci. 2007, 90(Suppl. 1):59. (Abstr.).
    • (2007) J. Dairy Sci. , vol.90 , Issue.SUPPL. 1 , pp. 59
    • Harvatine, K.J.1    Bauman, D.E.2
  • 15
    • 2642546601 scopus 로고    scopus 로고
    • Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein in the regulation of adipogenesis
    • Kast-Woelbern H.R., Dana S.L., Cesario R.M., Sun L., de Grandpre L.Y., Brooks M.E., Osburn D.L., Reifel-Miller A., Klausing K., Leibowitz M.D. Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein in the regulation of adipogenesis. J. Biol. Chem. 2004, 279:23908-23915.
    • (2004) J. Biol. Chem. , vol.279 , pp. 23908-23915
    • Kast-Woelbern, H.R.1    Dana, S.L.2    Cesario, R.M.3    Sun, L.4    de Grandpre, L.Y.5    Brooks, M.E.6    Osburn, D.L.7    Reifel-Miller, A.8    Klausing, K.9    Leibowitz, M.D.10
  • 17
    • 0037088683 scopus 로고    scopus 로고
    • Diminished hepatic response to fasting/refeeding and liver x receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
    • Liang G.S., Yang J., Horton J.D., Hammer R.E., Goldstein J.L., Brown M.S. Diminished hepatic response to fasting/refeeding and liver x receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J. Biol. Chem. 2002, 277:9520-9528.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9520-9528
    • Liang, G.S.1    Yang, J.2    Horton, J.D.3    Hammer, R.E.4    Goldstein, J.L.5    Brown, M.S.6
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real- time quantitative PCR and the 2(-ΔΔc)(T) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real- time quantitative PCR and the 2(-ΔΔc)(T) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 0030020577 scopus 로고    scopus 로고
    • Sterol regulation of acetyl coenzyme A carboxylase: A mechanism for coordinate control of cellular lipid
    • Lopez J.M., Bennett M.K., Sanchez H.B., Rosenfeld J.M., Osborne T.F. Sterol regulation of acetyl coenzyme A carboxylase: A mechanism for coordinate control of cellular lipid. Proc. Natl. Acad. Sci. USA 1996, 93:1049-1053.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1049-1053
    • Lopez, J.M.1    Bennett, M.K.2    Sanchez, H.B.3    Rosenfeld, J.M.4    Osborne, T.F.5
  • 20
    • 12644314084 scopus 로고    scopus 로고
    • Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter
    • Magana M.M., Osborne T.F. Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter. J. Biol. Chem. 1996, 271:32689-32694.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32689-32694
    • Magana, M.M.1    Osborne, T.F.2
  • 21
    • 69049118358 scopus 로고    scopus 로고
    • Differential expression and localization of lipid transporters in the bovine mammary gland during the pregnancy-lactation cycle
    • Mani O., Sorensen M.T., Sejrsen K., Bruckmaier R.M., Albrecht C. Differential expression and localization of lipid transporters in the bovine mammary gland during the pregnancy-lactation cycle. J. Dairy Sci. 2009, 92:3744-3756.
    • (2009) J. Dairy Sci. , vol.92 , pp. 3744-3756
    • Mani, O.1    Sorensen, M.T.2    Sejrsen, K.3    Bruckmaier, R.M.4    Albrecht, C.5
  • 22
    • 70449715072 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase (AMPK) inhibits fatty acid synthesis in bovine mammary epithelial cells
    • McFadden J.W., Corl B.A. Activation of AMP-activated protein kinase (AMPK) inhibits fatty acid synthesis in bovine mammary epithelial cells. Biochem. Biophys. Res. Commun. 2009, 390:388-393.
    • (2009) Biochem. Biophys. Res. Commun. , vol.390 , pp. 388-393
    • McFadden, J.W.1    Corl, B.A.2
  • 23
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα
    • Peet D.J., Turley S.D., Ma W., Janowski B.A., Lobaccaro J.M., Hammer R.E., Mangelsdorf D.J. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα. Cell 1998, 93:693-704.
    • (1998) Cell , vol.93 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3    Janowski, B.A.4    Lobaccaro, J.M.5    Hammer, R.E.6    Mangelsdorf, D.J.7
  • 26
    • 0028117755 scopus 로고
    • Ubiquitous receptor: A receptor that modulates gene activation by retinoic acid and thyroid-hormone receptors
    • Song C., Kokontis J.M., Hiipakka R.A., Liao S.S. Ubiquitous receptor: A receptor that modulates gene activation by retinoic acid and thyroid-hormone receptors. Proc. Natl. Acad. Sci. USA 1994, 91:10809-10813.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10809-10813
    • Song, C.1    Kokontis, J.M.2    Hiipakka, R.A.3    Liao, S.S.4
  • 27
    • 33845586243 scopus 로고    scopus 로고
    • The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317
    • Talukdar S., Hillgartner F.B. The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317. J. Lipid Res. 2006, 47:2451-2461.
    • (2006) J. Lipid Res. , vol.47 , pp. 2451-2461
    • Talukdar, S.1    Hillgartner, F.B.2
  • 28
    • 3042798281 scopus 로고    scopus 로고
    • ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins
    • Wang N., Lan D., Chen W., Matsuura F., Tall A.R. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc. Natl. Acad. Sci. USA 2004, 101:9774-9779.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9774-9779
    • Wang, N.1    Lan, D.2    Chen, W.3    Matsuura, F.4    Tall, A.R.5
  • 29
    • 36148955117 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells
    • Westerink W.M., Schoonen W.G. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells. Toxicol. In Vitro 2007, 21:1581-1591.
    • (2007) Toxicol. In Vitro , vol.21 , pp. 1581-1591
    • Westerink, W.M.1    Schoonen, W.G.2
  • 32
    • 0029963027 scopus 로고    scopus 로고
    • Establishment and characterization of a bovine mammary epithelial cell line with unique properties
    • Zavizion B., van Duffelen M., Schaeffer W., Politis I. Establishment and characterization of a bovine mammary epithelial cell line with unique properties. In Vitro Cell. Dev. Biol. Anim. 1996, 32:138-148.
    • (1996) In Vitro Cell. Dev. Biol. Anim. , vol.32 , pp. 138-148
    • Zavizion, B.1    van Duffelen, M.2    Schaeffer, W.3    Politis, I.4


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