메뉴 건너뛰기




Volumn , Issue , 2009, Pages

Impact of the pro12Ala polymorphism of the PPAR-gamma 2 gene on metabolic and clinical characteristics in the palestinian type 2 diabetic patients

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ORAL ANTIDIABETIC AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PROLINE; TRIACYLGLYCEROL;

EID: 72449154616     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2009/874126     Document Type: Article
Times cited : (26)

References (25)
  • 1
    • 33748997922 scopus 로고    scopus 로고
    • Type-2 diabetes: A cocktail of genetic discovery
    • supplement 2
    • Freeman H., Cox R. D., Type-2 diabetes: a cocktail of genetic discovery Human Molecular Genetics 2006 15 supplement 2 R202 R209
    • (2006) Human Molecular Genetics , vol.15
    • Freeman, H.1    Cox, R.D.2
  • 3
    • 72449192922 scopus 로고    scopus 로고
    • PPAR 2 Pro 12 Ala polymorphism and human health
    • He W., PPAR 2 Pro 12 Ala polymorphism and human health PPAR Research 2009 2009 15
    • (2009) PPAR Research , vol.2009 , pp. 15
    • He, W.1
  • 4
    • 47349107995 scopus 로고    scopus 로고
    • Peroxisome proliferators-activated receptor (PPAR) modulators and metabolic disorders
    • Cho M.-C., Lee K., Paik S.-G., Yoon D.-Y., Peroxisome proliferators-activated receptor (PPAR) modulators and metabolic disorders PPAR Research 2008 2008 14
    • (2008) PPAR Research , vol.2008 , pp. 14
    • Cho, M.-C.1    Lee, K.2    Paik, S.-G.3    Yoon, D.-Y.4
  • 5
    • 0036320603 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor- 2 Pro12Ala polymorphism
    • Stumvoll M., Hring H., The peroxisome proliferator-activated receptor- 2 Pro12Ala polymorphism Diabetes 2002 51 8 2341 2347
    • (2002) Diabetes , vol.51 , Issue.8 , pp. 2341-2347
    • Stumvoll, M.1    Hring, H.2
  • 6
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitution in PPAR 2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • Deeb S. S., Fajas L., Nemoto M., A Pro12Ala substitution in PPAR 2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity Nature Genetics 1998 20 3 284 287
    • (1998) Nature Genetics , vol.20 , Issue.3 , pp. 284-287
    • Deeb, S.S.1    Fajas, L.2    Nemoto, M.3
  • 7
    • 17944362462 scopus 로고    scopus 로고
    • Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor- 2 (PPAR - 2) gene in relation to insulin sensitivity among glucose tolerant Caucasians
    • Ek J., Andersen G., Urhammer S. A., Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor- 2 (PPAR- 2) gene in relation to insulin sensitivity among glucose tolerant Caucasians Diabetologia 2001 44 9 1170 1176
    • (2001) Diabetologia , vol.44 , Issue.9 , pp. 1170-1176
    • Ek, J.1    Andersen, G.2    Urhammer, S.A.3
  • 8
    • 0034745185 scopus 로고    scopus 로고
    • The Pro 12 → Ala substitution in PPAR- is associated with resistance to development of diabetes in the general population: Possible involvement in impairment of insulin secretion in individuals with type 2 diabetes
    • Mori H., Ikegami H., Kawaguchi Y., The Pro 12 → Ala substitution in PPAR- is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes Diabetes 2001 50 4 891 894
    • (2001) Diabetes , vol.50 , Issue.4 , pp. 891-894
    • Mori, H.1    Ikegami, H.2    Kawaguchi, Y.3
  • 9
    • 0034728762 scopus 로고    scopus 로고
    • The Pro12Ala polymorphism in PPAR 2 may confer resistance to type 2 diabetes
    • Hara K., Okada T., Tobe K., The Pro12Ala polymorphism in PPAR 2 may confer resistance to type 2 diabetes Biochemical and Biophysical Research Communications 2000 271 1 212 216
    • (2000) Biochemical and Biophysical Research Communications , vol.271 , Issue.1 , pp. 212-216
    • Hara, K.1    Okada, T.2    Tobe, K.3
  • 10
    • 30044432152 scopus 로고    scopus 로고
    • Examining the relationships between the Pro12Ala variant in PPARG and type 2 diabetes-related traits in UK samples
    • Zeggini E., Parkinson J. R. C., Halford S., Examining the relationships between the Pro12Ala variant in PPARG and type 2 diabetes-related traits in UK samples Diabetic Medicine 2005 22 12 1696 1700
    • (2005) Diabetic Medicine , vol.22 , Issue.12 , pp. 1696-1700
    • Zeggini, E.1    Parkinson, J.R.C.2    Halford, S.3
  • 11
    • 26444588777 scopus 로고    scopus 로고
    • Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population
    • Ghoussaini M., Meyre D., Lobbens S., Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population BMC Medical Genetics 2005 6, article 11
    • (2005) BMC Medical Genetics , vol.611
    • Ghoussaini, M.1    Meyre, D.2    Lobbens, S.3
  • 12
    • 21244439539 scopus 로고    scopus 로고
    • Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes
    • Hansen S. K., Nielsen E.-M. D., Ek J., Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes The Journal of Clinical Endocrinology Metabolism 2005 90 6 3629 3637
    • (2005) The Journal of Clinical Endocrinology Metabolism , vol.90 , Issue.6 , pp. 3629-3637
    • Hansen, S.K.1    Nielsen, E.-M.D.2    Ek, J.3
  • 13
    • 39049159123 scopus 로고    scopus 로고
    • Lack of association between the Pro 12 Ala polymorphism of the PPAR - 2 gene and type 2 diabetes mellitus in the Qatari consanguineous population
    • Badii R., Bener A., Zirie M., Lack of association between the Pro 12 Ala polymorphism of the PPAR- 2 gene and type 2 diabetes mellitus in the Qatari consanguineous population Acta Diabetologica 2008 45 1 15 21
    • (2008) Acta Diabetologica , vol.45 , Issue.1 , pp. 15-21
    • Badii, R.1    Bener, A.2    Zirie, M.3
  • 14
    • 17744398695 scopus 로고    scopus 로고
    • The peroxisome proliterator activated receptor 2 (PPAR 2) Pro12Ala variant: Lack of association with type 2 diabetes in obese and non obese Tunisian patients
    • Bouassida K. Z., Chouchane L., Jellouli K., The peroxisome proliterator activated receptor 2 (PPAR 2) Pro12Ala variant: lack of association with type 2 diabetes in obese and non obese Tunisian patients Diabetes Metabolism 2005 31 2 119 123
    • (2005) Diabetes Metabolism , vol.31 , Issue.2 , pp. 119-123
    • Bouassida, K.Z.1    Chouchane, L.2    Jellouli, K.3
  • 15
    • 0034186496 scopus 로고    scopus 로고
    • Significance of Pro 12 Ala mutation in peroxisome proliferator-activated receptor- 2 in Korean diabetic and obese subjects
    • Oh E. Y., Min K. M., Chung J. H., Significance of Pro 12 Ala mutation in peroxisome proliferator-activated receptor- 2 in Korean diabetic and obese subjects The Journal of Clinical Endocrinology Metabolism 2000 85 5 1801 1804
    • (2000) The Journal of Clinical Endocrinology Metabolism , vol.85 , Issue.5 , pp. 1801-1804
    • Oh, E.Y.1    Min, K.M.2    Chung, J.H.3
  • 16
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald W. T., Levy R. I., Fredrickson D. S., Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge Clinical Chemistry 1972 18 6 499 502
    • (1972) Clinical Chemistry , vol.18 , Issue.6 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 17
    • 33645988557 scopus 로고    scopus 로고
    • IRS1, KCNJ11, PPAR 2 and HNF-1 : ddo amino acid polymorphisms in these candidate genes support a shared aetiology between type 1 and type 2 diabetes?
    • Johansen A., Jensen D. P., Bergholdt R., IRS1, KCNJ11, PPAR 2 and HNF-1 : do amino acid polymorphisms in these candidate genes support a shared aetiology between type 1 and type 2 diabetes? Diabetes, Obesity and Metabolism 2006 8 1 75 82
    • (2006) Diabetes, Obesity and Metabolism , vol.8 , Issue.1 , pp. 75-82
    • Johansen, A.1    Jensen, D.P.2    Bergholdt, R.3
  • 18
    • 1642465495 scopus 로고    scopus 로고
    • Differential effects of the C1431T and Pro12Ala PPAR gene variants on plasma lipids and diabetes risk in an Asian population
    • Tai E. S., Corella D., Deurenberg-Yap M., Differential effects of the C1431T and Pro12Ala PPAR gene variants on plasma lipids and diabetes risk in an Asian population Journal of Lipid Research 2004 45 4 674 685
    • (2004) Journal of Lipid Research , vol.45 , Issue.4 , pp. 674-685
    • Tai, E.S.1    Corella, D.2    Deurenberg-Yap, M.3
  • 19
    • 0036222003 scopus 로고    scopus 로고
    • Pro12Ala polymorphism in the peroxisome proliferator-activated receptor- 2 (PPAR 2) is associated with higher levels of total cholesterol and LDL-cholesterol in male Caucasian type 2 diabetes patients
    • Zietz B., Barth N., Spiegel D., Schmitz G., Schlmerich J., Schffler A., Pro12Ala polymorphism in the peroxisome proliferator-activated receptor- 2 (PPAR 2) is associated with higher levels of total cholesterol and LDL-cholesterol in male Caucasian type 2 diabetes patients Experimental and Clinical Endocrinology and Diabetes 2002 110 2 60 66
    • (2002) Experimental and Clinical Endocrinology and Diabetes , vol.110 , Issue.2 , pp. 60-66
    • Zietz, B.1    Barth, N.2    Spiegel, D.3    Schmitz, G.4    Schlmerich, J.5    Schffler, A.6
  • 21
    • 0036217533 scopus 로고    scopus 로고
    • Evidence for greater oxidative substrate flexibility in male carriers of the Pro 12 Ala polymorphism in PPAR 2
    • Thamer C., Haap M., Volk A., Evidence for greater oxidative substrate flexibility in male carriers of the Pro 12 Ala polymorphism in PPAR 2 Hormone and Metabolic Research 2002 34 3 132 136
    • (2002) Hormone and Metabolic Research , vol.34 , Issue.3 , pp. 132-136
    • Thamer, C.1    Haap, M.2    Volk, A.3
  • 22
    • 0018520840 scopus 로고
    • Glucose clamp technique: A method for quantifying insulin secretion and resistance
    • DeFronzo R. A., Tobin J. D., Andres R., Glucose clamp technique: a method for quantifying insulin secretion and resistance The American Journal of Physiology 1979 237 3 E214 E223
    • (1979) The American Journal of Physiology , vol.237 , Issue.3
    • Defronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 24
    • 0036314819 scopus 로고    scopus 로고
    • The Proline 12 substitution in the peroxisome proliferator-activated receptor- 2 gene is associated with lower lipoprotein lipase activity in vivo
    • Schneider J., Kreuzer J., Hamann A., Nawroth P. P., Dugi K. A., The Proline 12 substitution in the peroxisome proliferator-activated receptor- 2 gene is associated with lower lipoprotein lipase activity in vivo Diabetes 2002 51 3 867 870
    • (2002) Diabetes , vol.51 , Issue.3 , pp. 867-870
    • Schneider, J.1    Kreuzer, J.2    Hamann, A.3    Nawroth, P.P.4    Dugi, K.A.5
  • 25
    • 0033060302 scopus 로고    scopus 로고
    • Pro12Ala substitution in the peroxisome proliferator-activated receptor- 2 is not associated with type 2 diabetes
    • Mancini F. P., Vaccaro O., Sabatino L., Pro12Ala substitution in the peroxisome proliferator-activated receptor- 2 is not associated with type 2 diabetes Diabetes 1999 48 7 1466 1468
    • (1999) Diabetes , vol.48 , Issue.7 , pp. 1466-1468
    • Mancini, F.P.1    Vaccaro, O.2    Sabatino, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.