Effects of DGAT1 variants on milk production traits in German cattle breeds

Journal of Animal Science

Volumn 81, Issue 8, 2003, Pages 1911-1918

  Thaller, G ^a,c   Kramer W ^a   Winter, A ^a   Kaupe, B ^b   Erhardt, G ^b   Fries, R ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c Alte Akademie 12   (Germany)

Author keywords

Cattle; Gene Expression; Gene Mapping; Milk Production Characteristics; Substitution

Indexed keywords

BOS TAURUS;

ACYLTRANSFERASE; DIACYLGLYCEROL ACYLTRANSFERASE; MILK PROTEIN;

ANIMAL; ARTICLE; CATTLE; CHEMISTRY; CHROMOSOME MAP; FAT INTAKE; FEMALE; GENE FREQUENCY; GENETIC SELECTION; GENETIC VARIABILITY; GENETICS; LACTATION; MILK; PHYSIOLOGY; QUANTITATIVE TRAIT LOCUS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SECRETION;

ACYLTRANSFERASES; ANIMALS; CATTLE; CHROMOSOME MAPPING; DIACYLGLYCEROL O-ACYLTRANSFERASE; DIETARY FATS; FEMALE; GENE FREQUENCY; LACTATION; MILK; MILK PROTEINS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; QUANTITATIVE TRAIT LOCI; SELECTION (GENETICS); VARIATION (GENETICS);

EID: 0642279220     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/2003.8181911x     Document Type: Article

References (16)

1. Bovenhuis, H., and C. Schrooten. 2002. Quantitative trait loci for milk production traits in dairy cattle. In Proc. of the 7th World Congress on Genetics Applied to Livestock Production, Montpellier, France.
2. Bovenhuis, H., J. A. Van Arendonk, and S. Korver. 1992. Associations between milk protein polymorphisms and milk production traits. J. Dairy Sci. 75:2549-2559.
3. Falconer, D. S., and T. F. C. Mackay. 1996. Quantitative genetics. 4th ed. Addison Wesley Longman Ltd., Essex, England.
4. Georges, M., D. Nielsen, M. Mackinnon, A. Mishra, R. Okimoto, A. T. Pasquino, L. S. Sargeant, A. Sorensen, M. R. Steele, X. Zhao, J. E. Womack, and I. Hoeschele. 1995. Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing. Genetics 139:907-920.
5. Grisart, B., W. Coppieters, F. Farnir, L. Karim, C. Ford, P. Berzi, N. Cambisano, M. Mni, S. Reid, P. Simon, R. Spelman, M. Georges, and R. Snell. 2002. Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition. Genome Res. 12:222-231.
6. Ikonen, T., H. Bovenhuis, M. Ojala, O. Ruottinen, and M. Georges. 2001. Associations between casein haplotypes and first lactation milk production traits in Finnish Ayrshire cows. J. Dairy Sci. 84:507-514.
7. Israel, C., and J. I. Weller. 1998. Estimation of candidate gene effects in dairy cattle populations. J. Dairy Sci. 81:1653-1662.
8. Ojala, M., T. R. Famula, and J. F. Medrano. 1997. Effects of milk protein genotypes on the variation for milk production traits of Holstein and Jersey cows in California. J. Dairy Sci. 80:1776-1785.
9. Renaville, R., N. Gengler, E. Vrech, A. Prandi, S. Massart, C. Corradini, C. Bertozzi, F. Mortiaux, A. Burny, and D. Portetelle. 1997. PIT-1 gene polymorphism, milk yield, and conformation traits for Italian Holstein-Friesian bulls. J. Dairy Sci. 80:3431-3438.
10. Sonstegard, T. S., C. P. Van Tassell, and M. S. Ashwell. 2001. Dairy cattle genomics: Tools to accelerate genetic improvement. J. Anim. Sci. 79(Suppl. E):307-315.
11. Thomsen, H., N. Reinsch, N. Xu, C. Looft, S. Grupe, C. Kühn, G. Brockmann, M. Schwerin, B. Leyhe-Horn, S. Hiendleder, G. Erhardt, I. Medjugorac, I. Russ, M. Förster, B. Brenig, F. Reinhardt, R. Reents, J. Blümel, G. Averdunk and E. Kalm. 2001. Comparison of estimated breeding values, daughter yield deviations and de-regressed proofs within a whole genome scan for QTL. J. Anim. Breed. Genet. 118:357-370.
12. VanRaden, P. M., and G. R. Wiggans. 1991. Derivation, calculation, and use of national animal model information. J. Dairy Sci. 74:2737-2746.
13. VIT. 2001. Zuchtwertschätzung, Vereinigte Informationssysteme Tierhaltung w.V., Verden/Aller, Germany.
14. Weller, J. I., Y. Kashi, and M. Soller. 1990. Power of daughter and granddaughter designs for determining linkage between marker loci and quantitative trait loci in dairy cattle. J. Dairy Sci. 73:2525-2537.
15. Winter, A., W. Krämer, F. A. Werner, S. Kollers, S. Kata, G. Durstewitz, J. Buitkamp, J.E. Womack, G. Thaller and R. Fries. 2002. Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content. Proc. Natl. Acad. Sci. U.S.A. 99:9300-9305.
16. Zhang, Q., D. Boichard, I. Hoeschele, C. Ernst, A. Eggen, B. Murkve, M. Pfister-Genskow, L. A. Witte, F. E. Grignola, P. Uimari, G. Thaller, and M. D. Bishop. 1998. Mapping quantitative trait loci for milk production and health of dairy cattle in a large outbred pedigree. Genetics 149:1959-1973.