Controlled release of thymosin beta 4 using a collagen-chitosan sponge scaffold augments cutaneous wound healing and increases angiogenesis in diabetic rats with hindlimb ischemia

Tissue Engineering - Part A

Volumn 21, Issue 3-4, 2015, Pages 541-549

  Ti, Dongdong ^a   Hao, Haojie ^a   Xia, Lei ^a   Tong, Chuan ^a   Liu, Jiejie ^a   Dong, Liang ^a   Xu, Shenjun ^a   Zhao, Yali ^b   Liu, Huiling ^a   Fu, Xiaobing ^a   Han, Weidong ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; CHITOSAN; COLLAGEN; ENDOTHELIAL CELLS; GENES; RATS; SCANNING ELECTRON MICROSCOPY;

ANGIOGENIC FACTOR; CONTROLLED RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FREEZE DRYING METHOD; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; INFLAMMATORY GENES; PROLIFERATIVE ACTIVITY; RE-EPITHELIALIZATION;

TISSUE REGENERATION;

CD31 ANTIGEN; CHITOSAN; COLLAGEN SPONGE; GLUCOSE; PROTEIN KINASE B; STREPTOZOCIN; THYMOSIN BETA4; VASCULOTROPIN; ANGIOGENIC FACTOR; BIOMATERIAL; COLLAGEN; DELAYED RELEASE FORMULATION; THYMOSIN; THYMOSIN BETA(4);

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; BLOOD VESSEL PERMEABILITY; CAPILLARY DENSITY; CELL MIGRATION; CELL PROLIFERATION; COLLAGEN CHITOSAN SPONGE TISSUE SCAFFOLD; COLLAGEN SYNTHESIS; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; DRUG DIFFUSION; ENCAPSULATION; ENDOTHELIUM CELL; EPITHELIZATION; FREEZE DRYING; HINDLIMB; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIMB ISCHEMIA; NONHUMAN; POROSITY; PRIORITY JOURNAL; RAT; SKIN INJURY; TENSILE STRENGTH; TISSUE ENGINEERING; TISSUE SCAFFOLD; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; VASCULARIZATION; WATER TRANSPORT; WOUND CLOSURE; WOUND HEALING; ADMINISTRATION AND DOSAGE; ANIMAL; ARTIFICIAL SKIN; BANDAGE; CHEMISTRY; DELAYED RELEASE FORMULATION; DEVICE FAILURE ANALYSIS; DIABETIC FOOT; DIFFUSION; DRUG EFFECTS; EQUIPMENT DESIGN; MALE; MATERIALS TESTING; SYNTHESIS; TREATMENT OUTCOME; WISTAR RAT;

RATTUS;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; BANDAGES; BIOCOMPATIBLE MATERIALS; CHITOSAN; COLLAGEN; DELAYED-ACTION PREPARATIONS; DIABETIC FOOT; DIFFUSION; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MALE; MATERIALS TESTING; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, WISTAR; SKIN, ARTIFICIAL; THYMOSIN; TISSUE SCAFFOLDS; TREATMENT OUTCOME; WOUND HEALING;

EID: 84923305074     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2013.0750     Document Type: Article

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