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Volumn 8, Issue 9, 2013, Pages

Loss of Innervation and Axon Plasticity Accompanies Impaired Diabetic Wound Healing

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; LGR6 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 84884745596     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075877     Document Type: Article
Times cited : (26)

References (36)
  • 1
    • 0020664172 scopus 로고
    • The epidemiology of lower extremity amputations in diabetic individuals
    • doi:10.2337/diacare.6.1.87
    • Most RS, Sinnock P, (1983) The epidemiology of lower extremity amputations in diabetic individuals. Diabetes Care 6: 87-91. doi:10.2337/diacare.6.1.87. PubMed: 6839926.
    • (1983) Diabetes Care , vol.6 , pp. 87-91
    • Most, R.S.1    Sinnock, P.2
  • 2
    • 33845768995 scopus 로고    scopus 로고
    • The neuropathic diabetic foot
    • doi:10.1038/ncpendmet0347
    • Rathur HM, Boulton AJ, (2007) The neuropathic diabetic foot. Nat Clin Pract Endocrinol Metab 3: 14-25. doi:10.1038/ncpendmet0347. PubMed: 17179926.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , pp. 14-25
    • Rathur, H.M.1    Boulton, A.J.2
  • 3
    • 27744448125 scopus 로고    scopus 로고
    • Wound healing and its impairment in the diabetic foot
    • doi:10.1016/S0140-6736(05)67700-8
    • Falanga V, (2005) Wound healing and its impairment in the diabetic foot. Lancet 366: 1736-1743. doi:10.1016/S0140-6736(05)67700-8. PubMed: 16291068.
    • (2005) Lancet , vol.366 , pp. 1736-1743
    • Falanga, V.1
  • 4
    • 0037961580 scopus 로고    scopus 로고
    • Diabetic foot ulcers
    • doi:10.1016/S0140-6736(03)13169-8
    • Jeffcoate WJ, Harding KG, (2003) Diabetic foot ulcers. Lancet 361: 1545-1551. doi:10.1016/S0140-6736(03)13169-8. PubMed: 12737879.
    • (2003) Lancet , vol.361 , pp. 1545-1551
    • Jeffcoate, W.J.1    Harding, K.G.2
  • 5
    • 65649129727 scopus 로고    scopus 로고
    • Altered molecular mechanisms of diabetic foot ulcers
    • doi:10.1177/1534734609337151
    • Blakytny R, Jude EB, (2009) Altered molecular mechanisms of diabetic foot ulcers. Int J Low Extrem Wounds 8: 95-104. doi:10.1177/1534734609337151. PubMed: 19443898.
    • (2009) Int J Low Extrem Wounds , vol.8 , pp. 95-104
    • Blakytny, R.1    Jude, E.B.2
  • 6
    • 33744780764 scopus 로고    scopus 로고
    • The molecular biology of chronic wounds and delayed healing in diabetes
    • doi:10.1111/j.1464-5491.2006.01773.x
    • Blakytny R, Jude E, (2006) The molecular biology of chronic wounds and delayed healing in diabetes. Diabet Med 23: 594-608. doi:10.1111/j.1464-5491.2006.01773.x. PubMed: 16759300.
    • (2006) Diabet Med , vol.23 , pp. 594-608
    • Blakytny, R.1    Jude, E.2
  • 7
    • 63049106661 scopus 로고    scopus 로고
    • Inflammation and neuropeptides: the connection in diabetic wound healing
    • doi:10.1017/S1462399409000945
    • Pradhan L, Nabzdyk C, Andersen ND, LoGerfo FW, Veves A, (2009) Inflammation and neuropeptides: the connection in diabetic wound healing. Expert Rev Mol Med 11: e2. doi:10.1017/S1462399409000945. PubMed: 19138453.
    • (2009) Expert Rev Mol Med , vol.11
    • Pradhan, L.1    Nabzdyk, C.2    Andersen, N.D.3    LoGerfo, F.W.4    Veves, A.5
  • 8
    • 67651180895 scopus 로고    scopus 로고
    • Advanced glycoxidation products and impaired diabetic wound healing
    • doi:10.1111/j.1524-475X.2009.00518.x
    • Peppa M, Stavroulakis P, Raptis SA, (2009) Advanced glycoxidation products and impaired diabetic wound healing. Wound Repair Regen 17: 461-472. doi:10.1111/j.1524-475X.2009.00518.x. PubMed: 19614910.
    • (2009) Wound Repair Regen , vol.17 , pp. 461-472
    • Peppa, M.1    Stavroulakis, P.2    Raptis, S.A.3
  • 9
    • 0032736857 scopus 로고    scopus 로고
    • Endogenously produced substance P contributes to lymphocyte proliferation induced by dendritic cells and direct TCR ligation
    • doi:10.1002/(SICI)1521-4141(199912)29:12
    • Lambrecht BN, Germonpré PR, Everaert EG, Carro-Muino I, De Veerman M, et al. (1999) Endogenously produced substance P contributes to lymphocyte proliferation induced by dendritic cells and direct TCR ligation. Eur J Immunol 29: 3815-3825.doi:10.1002/(SICI)1521-4141(199912)29:12. PubMed: 10601989.
    • (1999) Eur J Immunol , vol.29 , pp. 3815-3825
    • Lambrecht, B.N.1    Germonpré, P.R.2    Everaert, E.G.3    Carro-Muino, I.4    De Veerman, M.5
  • 10
    • 65349125939 scopus 로고    scopus 로고
    • Locally synthesized calcitonin gene-related Peptide has a critical role in peripheral nerve regeneration
    • doi:10.1097/NEN.0b013e31819ac71b
    • Toth CC, Willis D, Twiss JL, Walsh S, Martinez JA, et al. (2009) Locally synthesized calcitonin gene-related Peptide has a critical role in peripheral nerve regeneration. J Neuropathol Exp Neurol 68: 326-337. doi:10.1097/NEN.0b013e31819ac71b. PubMed: 19225405.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 326-337
    • Toth, C.C.1    Willis, D.2    Twiss, J.L.3    Walsh, S.4    Martinez, J.A.5
  • 11
    • 0028928473 scopus 로고
    • Calcitonin gene-related peptide promotes Schwann cell proliferation
    • doi:10.1083/jcb.129.3.789
    • Cheng L, Khan M, Mudge AW, (1995) Calcitonin gene-related peptide promotes Schwann cell proliferation. J Cell Biol 129: 789-796. doi:10.1083/jcb.129.3.789. PubMed: 7730412.
    • (1995) J Cell Biol , vol.129 , pp. 789-796
    • Cheng, L.1    Khan, M.2    Mudge, A.W.3
  • 12
    • 51649126753 scopus 로고    scopus 로고
    • Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide
    • doi:10.1073/pnas.0800767105
    • Toda M, Suzuki T, Hosono K, Hayashi I, Hashiba S, et al. (2008) Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide. Proc Natl Acad Sci U S A 105: 13550-13555. doi:10.1073/pnas.0800767105. PubMed: 18757746.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13550-13555
    • Toda, M.1    Suzuki, T.2    Hosono, K.3    Hayashi, I.4    Hashiba, S.5
  • 13
    • 46049086944 scopus 로고    scopus 로고
    • Roles of calcitonin gene-related peptide in facilitation of wound healing and angiogenesis
    • doi:10.1016/j.biopha.2008.02.003
    • Toda M, Suzuki T, Hosono K, Kurihara Y, Kurihara H, et al. (2008) Roles of calcitonin gene-related peptide in facilitation of wound healing and angiogenesis. Biomed Pharmacother 62: 352-359. doi:10.1016/j.biopha.2008.02.003. PubMed: 18430544.
    • (2008) Biomed Pharmacother , vol.62 , pp. 352-359
    • Toda, M.1    Suzuki, T.2    Hosono, K.3    Kurihara, Y.4    Kurihara, H.5
  • 14
    • 77954480424 scopus 로고    scopus 로고
    • PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons
    • doi:10.1523/JNEUROSCI.6271-09.2010
    • Christie KJ, Webber CA, Martinez JA, Singh B, Zochodne DW, (2010) PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons. J Neurosci 30: 9306-9315. doi:10.1523/JNEUROSCI.6271-09.2010. PubMed: 20610765.
    • (2010) J Neurosci , vol.30 , pp. 9306-9315
    • Christie, K.J.1    Webber, C.A.2    Martinez, J.A.3    Singh, B.4    Zochodne, D.W.5
  • 15
    • 47349113930 scopus 로고    scopus 로고
    • Activated RHOA and peripheral axon regeneration
    • doi:10.1016/j.expneurol.2008.04.023
    • Cheng C, Webber CA, Wang J, Xu Y, Martinez JA, et al. (2008) Activated RHOA and peripheral axon regeneration. Exp Neurol 212: 358-369. doi:10.1016/j.expneurol.2008.04.023. PubMed: 18554585.
    • (2008) Exp Neurol , vol.212 , pp. 358-369
    • Cheng, C.1    Webber, C.A.2    Wang, J.3    Xu, Y.4    Martinez, J.A.5
  • 16
    • 0033778784 scopus 로고    scopus 로고
    • The regenerative deficit of peripheral nerves in experimental diabetes: its extent, timing and possible mechanisms
    • doi:10.1093/brain/123.10.2118
    • Kennedy JM, Zochodne DW, (2000) The regenerative deficit of peripheral nerves in experimental diabetes: its extent, timing and possible mechanisms. Brain 123: 2118-2129. doi:10.1093/brain/123.10.2118. PubMed: 11004128.
    • (2000) Brain , vol.123 , pp. 2118-2129
    • Kennedy, J.M.1    Zochodne, D.W.2
  • 17
    • 79958216680 scopus 로고    scopus 로고
    • Local insulin and the rapid regrowth of diabetic epidermal axons
    • doi:10.1016/j.nbd.2011.04.012
    • Guo G, Kan M, Martinez JA, Zochodne DW, (2011) Local insulin and the rapid regrowth of diabetic epidermal axons. Neurobiol Dis 43: 414-421. doi:10.1016/j.nbd.2011.04.012. PubMed: 21530660.
    • (2011) Neurobiol Dis , vol.43 , pp. 414-421
    • Guo, G.1    Kan, M.2    Martinez, J.A.3    Zochodne, D.W.4
  • 18
    • 84861460226 scopus 로고    scopus 로고
    • Glucagon-like peptide 1, insulin, sensory neurons, and diabetic neuropathy
    • doi:10.1097/NEN.0b013e3182580673
    • Kan M, Guo G, Singh B, Singh V, Zochodne DW, (2012) Glucagon-like peptide 1, insulin, sensory neurons, and diabetic neuropathy. J Neuropathol Exp Neurol 71: 494-510. doi:10.1097/NEN.0b013e3182580673. PubMed: 22588388.
    • (2012) J Neuropathol Exp Neurol , vol.71 , pp. 494-510
    • Kan, M.1    Guo, G.2    Singh, B.3    Singh, V.4    Zochodne, D.W.5
  • 19
    • 48249101970 scopus 로고    scopus 로고
    • Distal degenerative sensory neuropathy in a long term type 2 diabetes rat model
    • doi:10.2337/db07-1737
    • Brussee V, Guo GF, Dong YY, Cheng C, Martinez JA, et al. (2008) Distal degenerative sensory neuropathy in a long term type 2 diabetes rat model. Diabetes 57: 1664-1673. doi:10.2337/db07-1737. PubMed: 18332094.
    • (2008) Diabetes , vol.57 , pp. 1664-1673
    • Brussee, V.1    Guo, G.F.2    Dong, Y.Y.3    Cheng, C.4    Martinez, J.A.5
  • 20
    • 14644410374 scopus 로고    scopus 로고
    • Experimental diabetic neuropathy and spontaneous recovery: Is there irreparable damage?
    • doi:10.2337/diabetes.54.3.830
    • Kennedy JM, Zochodne DW, (2005) Experimental diabetic neuropathy and spontaneous recovery: Is there irreparable damage? Diabetes 54: 830-837. doi:10.2337/diabetes.54.3.830. PubMed: 15734862.
    • (2005) Diabetes , vol.54 , pp. 830-837
    • Kennedy, J.M.1    Zochodne, D.W.2
  • 21
    • 78049487206 scopus 로고    scopus 로고
    • Dynamic plasticity of axons within a cutaneous milieu
    • doi:10.1523/JNEUROSCI.2919-10.2010
    • Cheng C, Guo GF, Martinez JA, Singh V, Zochodne DW, (2010) Dynamic plasticity of axons within a cutaneous milieu. J Neurosci 30: 14735-14744. doi:10.1523/JNEUROSCI.2919-10.2010. PubMed: 21048132.
    • (2010) J Neurosci , vol.30 , pp. 14735-14744
    • Cheng, C.1    Guo, G.F.2    Martinez, J.A.3    Singh, V.4    Zochodne, D.W.5
  • 22
    • 48749104018 scopus 로고    scopus 로고
    • Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice
    • doi:10.1016/j.neulet.2008.06.079
    • Beiswenger KK, Calcutt NA, Mizisin AP, (2008) Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice. Neurosci Lett 442: 267-272. doi:10.1016/j.neulet.2008.06.079. PubMed: 18619518.
    • (2008) Neurosci Lett , vol.442 , pp. 267-272
    • Beiswenger, K.K.1    Calcutt, N.A.2    Mizisin, A.P.3
  • 23
    • 39049150235 scopus 로고    scopus 로고
    • Skin and hair follicle innervation in experimental models: a guide for the exact and reproducible evaluation of neuronal plasticity
    • doi:10.1111/j.1600-0625.2007.00653.x
    • Hendrix S, Picker B, Liezmann C, Peters EM, (2008) Skin and hair follicle innervation in experimental models: a guide for the exact and reproducible evaluation of neuronal plasticity. Exp Dermatol 17: 214-227. doi:10.1111/j.1600-0625.2007.00653.x. PubMed: 18261087.
    • (2008) Exp Dermatol , vol.17 , pp. 214-227
    • Hendrix, S.1    Picker, B.2    Liezmann, C.3    Peters, E.M.4
  • 24
    • 1842372715 scopus 로고    scopus 로고
    • Hair cycle-dependent plasticity of skin and hair follicle innervation in normal murine skin
    • doi:10.1002/(SICI)1096-9861(19970929)386:3
    • Botchkarev VA, Eichmüller S, Johansson O, Paus R, (1997) Hair cycle-dependent plasticity of skin and hair follicle innervation in normal murine skin. J Comp Neurol 386: 379-395. doi:10.1002/(SICI)1096-9861(19970929)386:3. PubMed: 9303424.
    • (1997) J Comp Neurol , vol.386 , pp. 379-395
    • Botchkarev, V.A.1    Eichmüller, S.2    Johansson, O.3    Paus, R.4
  • 25
    • 77949360959 scopus 로고    scopus 로고
    • Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin
    • doi:10.1126/science.1184733
    • Snippert HJ, Haegebarth A, Kasper M, Jaks V, Van Es JH, et al. (2010) Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science 327: 1385-1389. doi:10.1126/science.1184733. PubMed: 20223988.
    • (2010) Science , vol.327 , pp. 1385-1389
    • Snippert, H.J.1    Haegebarth, A.2    Kasper, M.3    Jaks, V.4    Van Es, J.H.5
  • 26
    • 37149044785 scopus 로고    scopus 로고
    • Neurovascular factors in wound healing in the foot skin of type 2 diabetic subjects
    • doi:10.2337/dc07-1421
    • Krishnan ST, Quattrini C, Jeziorska M, Malik RA, Rayman G, (2007) Neurovascular factors in wound healing in the foot skin of type 2 diabetic subjects. Diabetes Care 30: 3058-3062. doi:10.2337/dc07-1421. PubMed: 17898089.
    • (2007) Diabetes Care , vol.30 , pp. 3058-3062
    • Krishnan, S.T.1    Quattrini, C.2    Jeziorska, M.3    Malik, R.A.4    Rayman, G.5
  • 27
    • 33746228385 scopus 로고    scopus 로고
    • Neurogenic factors in the impaired healing of diabetic foot ulcers
    • doi:10.1016/j.jss.2006.02.006
    • Galkowska H, Olszewski WL, Wojewodzka U, Rosinski G, Karnafel W, (2006) Neurogenic factors in the impaired healing of diabetic foot ulcers. J Surg Res 134: 252-258. doi:10.1016/j.jss.2006.02.006 PubMed: 16580687.
    • (2006) J Surg Res , vol.134 , pp. 252-258
    • Galkowska, H.1    Olszewski, W.L.2    Wojewodzka, U.3    Rosinski, G.4    Karnafel, W.5
  • 28
    • 0036436789 scopus 로고    scopus 로고
    • Diminished neuropeptide levels contribute to the impaired cutaneous healing response associated with diabetes mellitus
    • doi:10.1006/jsre.2002.6525
    • Gibran NS, Jang YC, Isik FF, Greenhalgh DG, Muffley LA, et al. (2002) Diminished neuropeptide levels contribute to the impaired cutaneous healing response associated with diabetes mellitus. J Surg Res 108: 122-128. doi:10.1006/jsre.2002.6525. PubMed: 12443724.
    • (2002) J Surg Res , vol.108 , pp. 122-128
    • Gibran, N.S.1    Jang, Y.C.2    Isik, F.F.3    Greenhalgh, D.G.4    Muffley, L.A.5
  • 29
    • 27144432427 scopus 로고    scopus 로고
    • EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy
    • doi:10.1111/j.1468-1331.2005.01260.x
    • Lauria G, Cornblath DR, Johansson O, McArthur JC, Mellgren SI, et al. (2005) EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy. Eur J Neurol 12: 747-758. doi:10.1111/j.1468-1331.2005.01260.x. PubMed: 16190912.
    • (2005) Eur J Neurol , vol.12 , pp. 747-758
    • Lauria, G.1    Cornblath, D.R.2    Johansson, O.3    McArthur, J.C.4    Mellgren, S.I.5
  • 30
    • 22144470885 scopus 로고    scopus 로고
    • Impaired peripheral nerve regeneration in diabetes mellitus
    • doi:10.1111/j.1085-9489.2005.0010205.x
    • Kennedy JM, Zochodne DW, (2005) Impaired peripheral nerve regeneration in diabetes mellitus. J Peripher Nerv Syst 10: 144-157. doi:10.1111/j.1085-9489.2005.0010205.x. PubMed: 15958126.
    • (2005) J Peripher Nerv Syst , vol.10 , pp. 144-157
    • Kennedy, J.M.1    Zochodne, D.W.2
  • 31
    • 0036300146 scopus 로고    scopus 로고
    • Influence of experimental diabetes on the microcirculation of injured peripheral nerve. Functional and morphological aspects
    • doi:10.2337/diabetes.51.7.2233
    • Kennedy JM, Zochodne DW, (2002) Influence of experimental diabetes on the microcirculation of injured peripheral nerve. Functional and morphological aspects. Diabetes 51: 2233-2240. doi:10.2337/diabetes.51.7.2233. PubMed: 12086955.
    • (2002) Diabetes , vol.51 , pp. 2233-2240
    • Kennedy, J.M.1    Zochodne, D.W.2
  • 33
    • 35148839080 scopus 로고    scopus 로고
    • Regenerative arrest of inflamed peripheral nerves: role of nitric oxide
    • doi:10.1097/WNR.0b013e3282f03fff
    • McDonald DS, Cheng C, Martinez JA, Zochodne DW, (2007) Regenerative arrest of inflamed peripheral nerves: role of nitric oxide. Neuroreport 18: 1635-1640. doi:10.1097/WNR.0b013e3282f03fff. PubMed: 17921859.
    • (2007) Neuroreport , vol.18 , pp. 1635-1640
    • McDonald, D.S.1    Cheng, C.2    Martinez, J.A.3    Zochodne, D.W.4
  • 34
    • 79955980980 scopus 로고    scopus 로고
    • Downregulation of PTEN at corneal wound sites accelerates wound healing through increased cell migration
    • doi:10.1167/iovs.10-5972
    • Cao L, Graue-Hernandez EO, Tran V, Reid B, Pu J, et al. (2011) Downregulation of PTEN at corneal wound sites accelerates wound healing through increased cell migration. Invest Ophthalmol Vis Sci 52: 2272-2278. doi:10.1167/iovs.10-5972. PubMed: 21212174.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 2272-2278
    • Cao, L.1    Graue-Hernandez, E.O.2    Tran, V.3    Reid, B.4    Pu, J.5
  • 35
    • 20244379418 scopus 로고    scopus 로고
    • Regulation of PTEN by Rho small GTPases
    • doi:10.1038/ncb1236
    • Li Z, Dong X, Wang Z, Liu W, Deng N, et al. (2005) Regulation of PTEN by Rho small GTPases. Nat Cell Biol 7: 399-404. doi:10.1038/ncb1236. PubMed: 15793569.
    • (2005) Nat Cell Biol , vol.7 , pp. 399-404
    • Li, Z.1    Dong, X.2    Wang, Z.3    Liu, W.4    Deng, N.5
  • 36
    • 33846561514 scopus 로고    scopus 로고
    • The diabetic foot
    • doi:10.1016/j.clindermatol.2006.09.015
    • Rathur HM, Boulton AJ, (2007) The diabetic foot. Clin Dermatol 25: 109-120. doi:10.1016/j.clindermatol.2006.09.015. PubMed: 17276208.
    • (2007) Clin Dermatol , vol.25 , pp. 109-120
    • Rathur, H.M.1    Boulton, A.J.2


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