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Volumn 24, Issue 7, 2010, Pages 2144-2151

Biological activities of thymosin β4 defined by active sites in short peptide sequences

Author keywords

Angiogenesis; Apoptosis; Inflammation; Wound healing

Indexed keywords

THYMOSIN BETA4;

EID: 77954447831     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-142307     Document Type: Review
Times cited : (117)

References (70)
  • 1
    • 24344500165 scopus 로고    scopus 로고
    • 4: Actin-sequestering protein moonlights to repair injured tissues
    • DOI 10.1016/j.molmed.2005.07.004, PII S1471491405001668
    • Goldstein, A. L., Hannappel, E., and Kleinman, H. K. (2005) Thymosin β4: actin-sequestering protein moonlights to repair injured tissues. Trends Mol. Med. 11, 421-429 (Pubitemid 41254045)
    • (2005) Trends in Molecular Medicine , vol.11 , Issue.9 , pp. 421-429
    • Goldstein, A.L.1    Hannappel, E.2    Kleinman, H.K.3
  • 2
    • 70349413077 scopus 로고    scopus 로고
    • The beta thymosins: Intracellular and extracellular activities of a versatile actin binding protein family
    • Mannherz, H. G., and Hannappel E. (2009) The beta thymosins: Intracellular and extracellular activities of a versatile actin binding protein family. Cell Motil. Cytoskeleton 66, 839-851
    • (2009) Cell Motil. Cytoskeleton , vol.66 , pp. 839-851
    • Mannherz, H.G.1    Hannappel, E.2
  • 3
    • 0013945220 scopus 로고
    • Preparation, assay, and partial purification of the thymic lymphocytopoietic factor (thymosin)
    • Goldstein, A. L., Slater, F. D., and White, A. (1966) Preparation, assay, and partial purification of the thymic lymphocytopoietic factor (thymosin). Proc. Natl. Acad. Sci. U. S. A. 56, 1010-1017
    • (1966) Proc. Natl. Acad. Sci. U. S. A. , vol.56 , pp. 1010-1017
    • Goldstein, A.L.1    Slater, F.D.2    White, A.3
  • 4
    • 0025856003 scopus 로고
    • 4 and Fx, an actin-sequestering peptide, are indistinguishable
    • Safer, D., Elzinga, M., and Nachmias, V. T. (1991) Thymosin beta 4 and Tx, an actin-sequestering peptide, are indistinguishable. J. Biol. Chem. 266, 4029-4032 (Pubitemid 21909312)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.7 , pp. 4029-4032
    • Safer, D.1    Elzinga, M.2    Nachmias, V.T.3
  • 5
    • 0030926245 scopus 로고    scopus 로고
    • 4 stimulates directional migration of human umbilical vein endothelial cells
    • Malinda, K. M., Goldstein, A. L., and Kleinman, H. K. (1997) Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells. FASEB J. 11, 474-481 (Pubitemid 27259989)
    • (1997) FASEB Journal , vol.11 , Issue.6 , pp. 474-481
    • Malinda, K.M.1    Goldstein, A.L.2    Kleinman, H.K.3
  • 6
    • 65549110635 scopus 로고    scopus 로고
    • Spatial coordination of actin polymerization and ILKAkt2 activity during endothelial cell migration
    • Fan, Y., Gong, Y., Ghosh, P. K., Graham, L. M., and Fox, P. L. (2009) Spatial coordination of actin polymerization and ILKAkt2 activity during endothelial cell migration. Dev. Cell 16, 661-674
    • (2009) Dev. Cell , vol.16 , pp. 661-674
    • Fan, Y.1    Gong, Y.2    Ghosh, P.K.3    Graham, L.M.4    Fox, P.L.5
  • 7
    • 66549099376 scopus 로고    scopus 로고
    • Overexpression of thymosin β4 increases pseudopodia formation in LNCaP prostate cancer cells
    • Ito, M., Iguchi, K., Usui, S., and Hirano, K. (2009) Overexpression of thymosin β4 increases pseudopodia formation in LNCaP prostate cancer cells. Biol. Pharm. Bull. 32, 1101-1104
    • (2009) Biol. Pharm. Bull. , vol.32 , pp. 1101-1104
    • Ito, M.1    Iguchi, K.2    Usui, S.3    Hirano, K.4
  • 8
    • 0344858002 scopus 로고    scopus 로고
    • 4 promotes tumor metastasis by stimulating migration and inducing angiogenesis through increased expression of vascular endothelial growth factor
    • 4 promotes tumor metastasis by stimulating migration and inducing angiogenesis through increased expression of vascular endothelial growth factor. J. Natl. Cancer Inst. 95, 1674-1680
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 1674-1680
    • Cha, H.-J.1    Jeong, M.-J.2    Kleinman, H.K.3
  • 12
    • 35548952702 scopus 로고    scopus 로고
    • Recombinant thymosin beta 4 can promote full-thickness cutaneous wound healing
    • DOI 10.1016/j.pep.2007.08.011, PII S1046592807001891
    • Li, X., Zheng, L., Peng, F., Qi, C., Zhang, X., Zhou, A., Liu, Z., and Wu, S. (2007) Recombinant thymosin beta 4 can promote full thickness cutaneous wound healing. Protein. Expr. Purif. 56, 229-236 (Pubitemid 350011045)
    • (2007) Protein Expression and Purification , vol.56 , Issue.2 , pp. 229-236
    • Li, X.1    Zheng, L.2    Peng, F.3    Qi, C.4    Zhang, X.5    Zhou, A.6    Liu, Z.7    Wu, S.8
  • 13
    • 0034776731 scopus 로고    scopus 로고
    • Thymosin beta 4 promotes corneal wound healing and modulates inflammatory mediators in vivo
    • DOI 10.1006/exer.2000.0985
    • Sosne, G., Chan, C. C., Thai, K., Kennedy, M., Szliter, E. A., Hazlett, L. D., and Kleinman, H. K. (2001) Thymosin beta4 promotes corneal wound healing and modulates inflammatory mediators in vivo. Exp. Eye Res. 72, 605-608 (Pubitemid 32977230)
    • (2001) Experimental Eye Research , vol.72 , Issue.5 , pp. 605-608
    • Sosne, G.1    Chi, C.C.2    Thai, K.3    Kennedy, M.4    Szliter, E.A.5    Hazlett, L.D.6    Kleinman, H.K.7
  • 14
    • 0036349917 scopus 로고    scopus 로고
    • Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury
    • DOI 10.1006/exer.2001.1125
    • Sosne, G., Szliter, E. A., Barrett, R., Kernacki, K. A., Kleinman, H., and Hazlett, L. D. (2002) Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury. Exp. Eye Res. 74, 293-299 (Pubitemid 34948404)
    • (2002) Experimental Eye Research , vol.74 , Issue.2 , pp. 293-299
    • Sosne, G.1    Szliter, E.A.2    Barrett, R.3    Kernacki, K.A.4    Kleinman, H.5    Hazlett, L.D.6
  • 16
    • 33846243239 scopus 로고    scopus 로고
    • Thymosin β4 induces adult epicardial progenitor mobilization and neovascularization
    • DOI 10.1038/nature05383, PII NATURE05383
    • Smart, N., Risebro, C. A., Melville, A. A. D., Moses, K., Schwartz, R. J., Chien, K. R., and Riley, P. R. (2007) Thymosin beta 4 induces adult epicardial progenitor mobilization and neovascularization. Nature 44, 177-182 (Pubitemid 46095717)
    • (2007) Nature , vol.445 , Issue.7124 , pp. 177-182
    • Smart, N.1    Risebro, C.A.2    Melville, A.A.D.3    Moses, K.4    Schwartz, R.J.5    Chien, K.R.6    Riley, P.R.7
  • 18
    • 34249867441 scopus 로고    scopus 로고
    • Matrix metalloproteinase activity is necessary for thymosin beta 4 promotion of epithelial cell migration
    • Qui, P., Kurpas-Wheater, M., and Sosne, G. (2007) Matrix metalloproteinase activity is necessary for thymosin beta 4 promotion of epithelial cell migration. J. Cell. Physiol. 212, 165-173
    • (2007) J. Cell. Physiol. , vol.212 , pp. 165-173
    • Qui, P.1    Kurpas-Wheater, M.2    Sosne, G.3
  • 20
    • 44749087582 scopus 로고    scopus 로고
    • Thymosin beta4 is involved in stabilin-2-mediated apoptotic cell engulfment
    • So, I. S., Partk, S. Y., and Kim, I. S. (2008) Thymosin beta4 is involved in stabilin-2-mediated apoptotic cell engulfment. FEBS Lett. 582, 2161-2166
    • (2008) FEBS Lett. , vol.582 , pp. 2161-2166
    • So, I.S.1    Partk, S.Y.2    Kim, I.S.3
  • 22
    • 2142763869 scopus 로고    scopus 로고
    • Thymosin-β4 inhibits corneal epithelial cell apoptosis after ethanol exposure in vitro
    • DOI 10.1167/iovs.03-1002
    • Sosne, G., Siddiqi, A., and Kurpas-Wheater, M. (2004) Thymosin beta 4 inhibits corneal epithelial cell apoptosis after ethanol exposure in vitro. Invest. Opthalmol. Vis. Sci. 45, 1095-1200 (Pubitemid 38869013)
    • (2004) Investigative Ophthalmology and Visual Science , vol.45 , Issue.4 , pp. 1095-1100
    • Sosne, G.1    Siddiqi, A.2    Kurpakus-Wheater, M.3
  • 23
    • 9644281738 scopus 로고    scopus 로고
    • Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
    • DOI 10.1038/nature03000
    • Bock-Marquette, I., Saxena, A., White, M. D., DiMaio, M., and Srivastava, D. (2004) Thymosin beta 4 activates integrin-linked kinase and promotes cardiac cell migration, survival, and cardiac repair. Nature 432, 466-472 (Pubitemid 39576522)
    • (2004) Nature , vol.432 , Issue.7016 , pp. 466-472
    • Bock-Marquette, I.1    Saxena, A.2    White, M.D.3    Dimaio, J.M.4    Srivastava, D.5
  • 24
    • 47049124833 scopus 로고    scopus 로고
    • Thymosin beta 4 upregulates anti-oxidative enzymes and protects human corneal epithelial cells against oxidative damage
    • Ho, J. H., Tseng, K. C., Ma, W. H., Chen, K. H., Lee, O. K., and Su, Y. (2008) Thymosin beta 4 upregulates anti-oxidative enzymes and protects human corneal epithelial cells against oxidative damage. Br. J. Opthalmol. 92, 992-997
    • (2008) Br. J. Opthalmol. , vol.92 , pp. 992-997
    • Ho, J.H.1    Tseng, K.C.2    Ma, W.H.3    Chen, K.H.4    Lee, O.K.5    Su, Y.6
  • 29
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn, T. A. (2008) Cellular and molecular mechanisms of fibrosis. J. Pathol. 214, 199-210
    • (2008) J. Pathol. , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 31
    • 0019853771 scopus 로고
    • Modulation of terminal deoxynucleotidyl transferase activity by thymosin
    • Hu, S-K., Low, T. L. K., and Goldstein, A. L. (1981) Modulation of terminal deoxynucleotidyl transferase activity by thymosin. Mol. Cell. Biochem. 41, 49-58 (Pubitemid 12142400)
    • (1981) Molecular and Cellular Biochemistry , vol.41 , Issue.SPEC. NO , pp. 49-58
    • Hu, S.-K.1    Low, T.L.K.2    Goldstein, A.L.3
  • 32
    • 0017797118 scopus 로고
    • Induction in vivo and in vitro of terminal deoxynucleotidyl transferase by thymosin in bone marrow cells from athymic mice
    • Pazmino, N. H., Ihle, J. N., Goldstein, A. L. (1978) Induction in vivo and in vitro of terminal deoxynucleotidyl transferase by thymosin in bone marrow cells from athymic mice. J. Exp. Med. 147, 708-718
    • (1978) J. Exp. Med. , vol.147 , pp. 708-718
    • Pazmino, N.H.1    Ihle, J.N.2    Goldstein, A.L.3
  • 33
    • 0027332655 scopus 로고
    • Alterations in actin-binding beta-thymosin expression accompany neuronal differentiation and migration in rat cerebellum
    • Border, B., Lin, S. C., Griffin, W. W., Pardues, S., and Morrison-Bogorad, M. (1993) Alterations in actin-binding beta thyosin expression accompany neuronal differentiation and migration in rat cerebellum. J. Neurochem. 61, 2104-2114 (Pubitemid 2012500)
    • (1993) Journal of Neurochemistry , vol.61 , Issue.6 , pp. 2104-2114
    • Border, B.G.1    Lin, S.C.2    Griffin, S.T.3    Pardue, S.4    Morrison-Bogorad, M.5
  • 34
    • 0023404365 scopus 로고
    • Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells
    • Leonard, D. G. B., Ziff, E. S., and Greene, L. A. (1987) Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Mol. Cell. Biol. 7, 3156-3167
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3156-3167
    • Leonard, D.G.B.1    Ziff, E.S.2    Greene, L.A.3
  • 35
    • 0029743803 scopus 로고    scopus 로고
    • 4 mRNA following focal brain ischemia
    • Vartianen, N., Pyykonen, I., Hokfelt, T., and Koistinaho, J. (1996) Induction of thymosin beta 4 mRNA following focal brain ischemia. NeuroReport. 7, 1613-1616 (Pubitemid 26332334)
    • (1996) NeuroReport , vol.7 , Issue.10 , pp. 1613-1616
    • Vartiainen, N.1    Pyykonen, I.2    Hokfelt, T.3    Koistinaho, J.4
  • 37
    • 52549114744 scopus 로고    scopus 로고
    • The promotive effects of thymosin beta 4 on neuronal survival and neurite outgrowth by upregulating L1 expression
    • Yang, H., Cheng, X., Yao, Q., Li, J., and Ju, G. (2008) The promotive effects of thymosin beta 4 on neuronal survival and neurite outgrowth by upregulating L1 expression. Neurochem. Res. 33, 2269-2280
    • (2008) Neurochem. Res. , vol.33 , pp. 2269-2280
    • Yang, H.1    Cheng, X.2    Yao, Q.3    Li, J.4    Ju, G.5
  • 38
    • 70449518280 scopus 로고    scopus 로고
    • Neurological functional recovery after thymosin beta 4 treatment in mice with experimental auto encephalomyelitis
    • Zhang J, Zhang, Z. G., Morris, D., Li, Y. Elias, S. B., and Chopp, M. (2009) Neurological functional recovery after thymosin beta 4 treatment in mice with experimental auto encephalomyelitis. Neuroscience 164, 1887-1893
    • (2009) Neuroscience , vol.164 , pp. 1887-1893
    • Zhang, J.1    Zhang, Z.G.2    Morris, D.3    Li, Y.4    Elias, S.B.5    Chopp, M.6
  • 39
    • 35348989639 scopus 로고    scopus 로고
    • Thymosin beta 4 and the eye: I can see clearly now
    • Sosne, G., Qui, P., and Kurpakas-Wheaater, M. (2007) Thymosin beta 4 and the eye: I can see clearly now. Ann. N. Y. Acad. Sci. 1112, 114-122
    • (2007) Ann. N. Y. Acad. Sci. , vol.1112 , pp. 114-122
    • Sosne, G.1    Qui, P.2    Kurpakas-Wheaater, M.3
  • 40
    • 33947200192 scopus 로고    scopus 로고
    • Thymosin beta 4 suppression of corneal NFκB: A potential anti-inflammatory pathway
    • DOI 10.1016/j.exer.2006.12.004, PII S001448350600460X
    • Sosne, G., Qui, P., Christopherson, P. L., and Wheater, M. K. (2007) Thymosin beta 4 suppression of corrneal NFKappaB: a potential anti-inflammatory pathway. Exp. Eye Res. 84, 663-669 (Pubitemid 46420439)
    • (2007) Experimental Eye Research , vol.84 , Issue.4 , pp. 663-669
    • Sosne, G.1    Qiu, P.2    Christopherson, P.L.3    Wheater, M.K.4
  • 42
    • 0032735680 scopus 로고    scopus 로고
    • Thymosin beta 4 sulfoxidee is an anti inflammatory agent generated by monocytes in the presence of glucocorticoids
    • Young, D. J., Lawrence, A. J., mac Lean, A. G., Leung, B. P., McInnes, I. B., Canas, B., Pappin, D. J., and Stevenson, J. D. (1999) Thymosin beta 4 sulfoxidee is an anti inflammatory agent generated by monocytes in the presence of glucocorticoids. Nat. Med. 5, 1424-1427
    • (1999) Nat. Med. , vol.5 , pp. 1424-1427
    • Young, D.J.1    Lawrence, A.J.2    Mac Lean, A.G.3    Leung, B.P.4    McInnes, I.B.5    Canas, B.6    Pappin, D.J.7    Stevenson, J.D.8
  • 43
    • 58749089339 scopus 로고    scopus 로고
    • Embryonic endothelial progenitor cell-mediated cardioprotection requires thymosin beta 4
    • Kupatt, C., Bock-Marquette, I., and Boekstegers, P. (2008) Embryonic endothelial progenitor cell-mediated cardioprotection requires thymosin beta 4. Trends Cardiovasc. Med. 18, 205-210
    • (2008) Trends Cardiovasc. Med. , vol.18 , pp. 205-210
    • Kupatt, C.1    Bock-Marquette, I.2    Boekstegers, P.3
  • 44
    • 33750989327 scopus 로고    scopus 로고
    • Therapeutic effect of thymosin beta 4 and its derivative N-acetyl-seryly-aspartyl-lysyl-proline (Ac-SDKP) on cardiac healing after infarction
    • Cavasin, M. S. (2006) Therapeutic effect of thymosin beta 4 and its derivative N-acetyl-seryly-aspartyl-lysyl-proline (Ac-SDKP) on cardiac healing after infarction. Am. J. Cardiovasc. Drugs 6, 305-311
    • (2006) Am. J. Cardiovasc. Drugs , vol.6 , pp. 305-311
    • Cavasin, M.S.1
  • 45
    • 0027189729 scopus 로고
    • Actin is a surface component of calf pulmonary artery endothelial cells in culture
    • Morianu, J., Fett, J. W., Riordan, J. F., and Vallee, B. L. (1993) Actin is a surface component of calf pulmonary artery endothelial cells in culture. Proc. Natl. Acad. Sci. U. S. A. 90, 3815-3819
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 3815-3819
    • Morianu, J.1    Fett, J.W.2    Riordan, J.F.3    Vallee, B.L.4
  • 46
    • 33751084312 scopus 로고    scopus 로고
    • In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteomics
    • DOI 10.1002/pmic.200600163
    • Huang, C. M., Wang, C. C., Barnes, S., and Elmets, V. A. (2006) In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteonomics. Proteonomics 6, 5805-5814 (Pubitemid 44764017)
    • (2006) Proteomics , vol.6 , Issue.21 , pp. 5805-5814
    • Huang, C.-M.1    Wang, C.-C.2    Barnes, S.3    Elmets, C.A.4
  • 47
    • 36148972458 scopus 로고    scopus 로고
    • Thymosin beta 4 expression and nuclear transport are regulated by hMLH1
    • Breiger, A., Plotz, G., Zeuzem, S., and Trojan, J. (2007) Thymosin beta 4 expression and nuclear transport are regulated by hMLH1. Biochem. Biophys. Res. Commun. 364, 731-736
    • (2007) Biochem. Biophys. Res. Commun. , vol.364 , pp. 731-736
    • Breiger, A.1    Plotz, G.2    Zeuzem, S.3    Trojan, J.4
  • 48
    • 38349125347 scopus 로고    scopus 로고
    • Ku80 as novel receptor for thymosin beta 4 that mediates its intracellular activity different from G-actin sequestering
    • Bednarek, R., Boncel, J., Smolarczyk, K., Cierniewska-Cieslak, A., Wyroba, E., and Cierniewski, C. S. (2008) Ku80 as novel receptor for thymosin beta 4 that mediates its intracellular activity different from G-actin sequestering. J. Biol. Chem. 283, 1534-1544
    • (2008) J. Biol. Chem. , vol.283 , pp. 1534-1544
    • Bednarek, R.1    Boncel, J.2    Smolarczyk, K.3    Cierniewska-Cieslak, A.4    Wyroba, E.5    Cierniewski, C.S.6
  • 50
    • 0030698849 scopus 로고    scopus 로고
    • High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: A new marker of chronic angiotensin-converting enzyme inhibition
    • Azizi, M., Ezan, E., Nicolet, L., Grognet, J. M., and Menard, J. (1997) High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: a new marker of chronic angiotensin-converting enzyme inhibition. Hypertension 30, 1015-1019
    • (1997) Hypertension , vol.30 , pp. 1015-1019
    • Azizi, M.1    Ezan, E.2    Nicolet, L.3    Grognet, J.M.4    Menard, J.5
  • 51
    • 2342466215 scopus 로고    scopus 로고
    • Prolyly oligopeptidase is involved in release of the anti fibrotic peptide As-SDKP
    • Cavasin, M. A., Rhaleb, N. E., Yang, X. P., and Carretero, O. A. (2004) Prolyly oligopeptidase is involved in release of the anti fibrotic peptide As-SDKP. Hypertension 43, 1140-1145
    • (2004) Hypertension , vol.43 , pp. 1140-1145
    • Cavasin, M.A.1    Rhaleb, N.E.2    Yang, X.P.3    Carretero, O.A.4
  • 52
    • 2342586811 scopus 로고    scopus 로고
    • Reduction of cardiac fibrosis decreases systolic performance with an affect on diastolic function in hypertensive rats
    • Cingolani, O. H., Yang, X-P., Liu Y-H., Villanueva, M., Rhaleb, N. E., and Carretero, O. A. (2004) Reduction of cardiac fibrosis decreases systolic performance with an affect on diastolic function in hypertensive rats. Hypertension 43, 1067-1073
    • (2004) Hypertension , vol.43 , pp. 1067-1073
    • Cingolani, O.H.1    Yang, X.-P.2    Liu, Y.-H.3    Villanueva, M.4    Rhaleb, N.E.5    Carretero, O.A.6
  • 54
    • 0027374114 scopus 로고
    • Direct and reversible inhibitory effect of the tetrapeptide acetylN-ser-asp-lys- Pro (seraspenide) on the growth of human CD34+ subpopulations in response to growth factors
    • Bonnet, D., Lemoine, F. M., Pontvert-Deluq, S., Baillou, C., Najman, A., and Guigon, M. (1993) Direct and reversible inhibitory effect of the tetrapeptide acetylN-ser-asp-lys- pro (seraspenide) on the growth of human CD34+ subpopulations in response to growth factors. Blood 82, 3307-3314
    • (1993) Blood , vol.82 , pp. 3307-3314
    • Bonnet, D.1    Lemoine, F.M.2    Pontvert-Deluq, S.3    Baillou, C.4    Najman, A.5    Guigon, M.6
  • 56
    • 0842267835 scopus 로고    scopus 로고
    • AcSDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction
    • Yang, F., Yang, X. P., Liu, Y. H., Xu, J., Cingolani, O., Rhaleb, N. E., and Carretero, O. A. (2003) AcSDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction. Hypertension 43, 229-236
    • (2003) Hypertension , vol.43 , pp. 229-236
    • Yang, F.1    Yang, X.P.2    Liu, Y.H.3    Xu, J.4    Cingolani, O.5    Rhaleb, N.E.6    Carretero, O.A.7
  • 60
    • 0035095260 scopus 로고    scopus 로고
    • Antifibrotic effects of N-acetyl-seryl-aspartyl-lysyl-prline on the heart and kidney in aldosterone-salt hyptensive rats
    • Peng, H., Carretero, O. A., Raji, L., Yang, F., Kapke, A., and Rhaleb, N. E. (2001) Antifibrotic effects of N-acetyl-seryl-aspartyl-lysyl-prline on the heart and kidney in aldosterone-salt hyptensive rats. Hypertension 37, 794-800
    • (2001) Hypertension , vol.37 , pp. 794-800
    • Peng, H.1    Carretero, O.A.2    Raji, L.3    Yang, F.4    Kapke, A.5    Rhaleb, N.E.6
  • 63
    • 17444437933 scopus 로고    scopus 로고
    • The tetrapeptide AcSDKP, a negative regulator of cell cycle entry, inhibits the proliferation of human and chicken lymphocytes
    • Volkov, Quere, L., P., Coudert, F., Compte, L., Antipov, Y., and Praloran, V. (1996) the tetrapeptide AcSDKP, a negative regulator of cell cycle entry, inhibits the proliferation of human and chicken lymphocytes. Cell. Immunol. 168, 302-302
    • (1996) Cell. Immunol. , vol.168 , pp. 302-302
    • Volkov1    Quere, L.P.2    Coudert, F.3    Compte, L.4    Antipov, Y.5    Praloran, V.6
  • 65
  • 67
    • 0037377993 scopus 로고    scopus 로고
    • N-acetyl seryl-aspartyl-lysly-proline inhibits TGF-beta mediated plasminogen activator inhibitor-1 expression via an inhibition of the Smad pathway in human mesangial cells
    • Kanasaki, K., Koya, D., Sugimoto, T., Isono, M., Kashiwagi, A., and Haneda, M. (2002) N-acetyl seryl-aspartyl-lysly-proline inhibits TGF-beta mediated plasminogen activator inhibitor-1 expression via an inhibition of the Smad pathway in human mesangial cells. Am. Soc. Nephrol. 14, 863-872
    • (2002) Am. Soc. Nephrol. , vol.14 , pp. 863-872
    • Kanasaki, K.1    Koya, D.2    Sugimoto, T.3    Isono, M.4    Kashiwagi, A.5    Haneda, M.6
  • 68
    • 33847393190 scopus 로고    scopus 로고
    • Thymosin beta 4 and thymosin beta 4-derived peptides induce mast cell exocytosis
    • Wyczoikowska, J., Walczak-Drzewiecka, A., Wangner, W., and Dastych, J. (2007) Thymosin beta 4 and thymosin beta 4-derived peptides induce mast cell exocytosis. Peptides 28, 752-759
    • (2007) Peptides , vol.28 , pp. 752-759
    • Wyczoikowska, J.1    Walczak-Drzewiecka, A.2    Wangner, W.3    Dastych, J.4
  • 69
    • 38149091473 scopus 로고    scopus 로고
    • Thymosin beta 4 and its N-terminal tetrapeptide, AcSDKP, inhibit proliferation, and induce dysplastic, non-apoptotic nuclei and degranulation of mast cells
    • Leeananasakisiri, W., Desimone, S. K., Huff, T., Hannappel, E., and Huff, T. F. (2004) Thymosin beta 4 and its N-terminal tetrapeptide, AcSDKP, inhibit proliferation, and induce dysplastic, non-apoptotic nuclei and degranulation of mast cells. Chem. Biodivers. 1, 1091-1100
    • (2004) Chem. Biodivers. , vol.1 , pp. 1091-1100
    • Leeananasakisiri, W.1    Desimone, S.K.2    Huff, T.3    Hannappel, E.4    Huff, T.F.5
  • 70
    • 0037282380 scopus 로고    scopus 로고
    • Thymosin beta 4 and a synthetic peptide containing the actin- Binding domain promote dermal wound repair in db/db mice and in aged mice
    • Philp, D., Badamchian, M., Scheremta, B., Nguyen, M., Goldstein, A. L., and Kleinman, H. K. (2003) Thymosin beta 4 and a synthetic peptide containing the actin- binding domain promote dermal wound repair in db/db mice and in aged mice. Wound Repair Regen. 11, 19-24
    • (2003) Wound Repair Regen. , vol.11 , pp. 19-24
    • Philp, D.1    Badamchian, M.2    Scheremta, B.3    Nguyen, M.4    Goldstein, A.L.5    Kleinman, H.K.6


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