TRPA1 is essential for the vascular response to environmental cold exposure

Nature Communications

Volumn 5, Issue , 2014, Pages

  Aubdool, Aisah A ^a   Graepel, Rabea ^a   Kodji, Xenia ^a   Alawi, Khadija M ^a   Bodkin, Jennifer V ^a   Srivastava, Salil ^a   Gentry, Clive ^a   Heads, Richard ^a   Grant, Andrew D ^a   Fernandes, Elizabeth S ^a   Bevan, Stuart ^a   Brain, Susan D ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; NITRIC OXIDE; RHO KINASE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; 2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE; ACETANILIDE DERIVATIVE; CALCITONIN GENE RELATED PEPTIDE; MEMBRANE PROTEIN; MLC1 PROTEIN, MOUSE; NEURONAL NITRIC OXIDE SYNTHASE; NOS1 PROTEIN, MOUSE; PURINE DERIVATIVE; SUBSTANCE P; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRPA1 PROTEIN, MOUSE;

ANTAGONISM; BLOOD; CLIMATE EFFECT; COLD TOLERANCE; DISEASE INCIDENCE; ENZYME ACTIVITY; PEPTIDE; SENSOR; SKIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOWMETRY; BLOOD VESSEL REACTIVITY; COLD EXPOSURE; CONTROLLED STUDY; DOPPLER FLOWMETRY; ENVIRONMENTAL EXPOSURE; MALE; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; ROOM TEMPERATURE; SENSORY NERVE; SKIN BLOOD FLOW; SKIN TEMPERATURE; VASOCONSTRICTION; WATER IMMERSION; ADVERSE EFFECTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; COLD; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; HINDLIMB; HYPOTHERMIA; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKIN; VASCULARIZATION; VASODILATATION;

MURINAE;

ACETANILIDES; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; COLD TEMPERATURE; GENE EXPRESSION REGULATION; HINDLIMB; HYPOTHERMIA; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; PHOSPHORYLATION; PURINES; RECEPTORS, ADRENERGIC, ALPHA; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SKIN; SUBSTANCE P; SUPEROXIDES; TRANSIENT RECEPTOR POTENTIAL CHANNELS; VASOCONSTRICTION; VASODILATION;

EID: 84923241419     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6732     Document Type: Article

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