-
1
-
-
84864255882
-
The origin and evolution of mutations in acute myeloid leukemia
-
Welch JS, Ley TJ, Link DC, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell 2012; 150:264-278.
-
(2012)
Cell
, vol.150
, pp. 264-278
-
-
Welch, J.S.1
Ley, T.J.2
Link, D.C.3
-
3
-
-
84908125658
-
Clonal dynamics of native haematopoiesis
-
Sun J, Ramos A, Chapman B, et al. Clonal dynamics of native haematopoiesis. Nature 2014; 514:322-327.
-
(2014)
Nature
, vol.514
, pp. 322-327
-
-
Sun, J.1
Ramos, A.2
Chapman, B.3
-
4
-
-
0002234927
-
Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates
-
Kim HJ, Tisdale JF, Wu T, et al. Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates. Blood 2000; 96:1-8.
-
(2000)
Blood
, vol.96
, pp. 1-8
-
-
Kim, H.J.1
Tisdale, J.F.2
Wu, T.3
-
5
-
-
84899817242
-
Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis
-
Holstege H, Pfeiffer W, Sie D, et al. Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis. Genome Res 2014; 24:733-742.
-
(2014)
Genome Res
, vol.24
, pp. 733-742
-
-
Holstege, H.1
Pfeiffer, W.2
Sie, D.3
-
6
-
-
0023202032
-
Clonal development, stem-cell differentiation, and clinical remissions in acute nonlymphocytic leukemia
-
Fialkow PJ, Singer JW, Raskind WH, et al. Clonal development, stem-cell differentiation, and clinical remissions in acute nonlymphocytic leukemia. N Engl J Med 1987; 317:468-473.
-
(1987)
N Engl J Med
, vol.317
, pp. 468-473
-
-
Fialkow, P.J.1
Singer, J.W.2
Raskind, W.H.3
-
7
-
-
84868208186
-
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
-
Busque L, Patel JP, Figueroa ME, et al. Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nat Genet 2012;44:1179-1181.
-
(2012)
Nat Genet
, vol.44
, pp. 1179-1181
-
-
Busque, L.1
Patel, J.P.2
Figueroa, M.E.3
-
8
-
-
84930003179
-
Age-related mutations associated with clonal hematopoietic expansion and malignancies
-
Xie M, Lu C, Wang J, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med 2014; 20:1472-1478.
-
(2014)
Nat Med
, vol.20
, pp. 1472-1478
-
-
Xie, M.1
Lu, C.2
Wang, J.3
-
9
-
-
0025819093
-
Clonal remissions in acute nonlymphocytic leukemia: Evidence for a multistep pathogenesis of the malignancy
-
Fialkow PJ, Janssen JW, Bartram CR. Clonal remissions in acute nonlymphocytic leukemia: evidence for a multistep pathogenesis of the malignancy. Blood 1991; 77:1415-1417.
-
(1991)
Blood
, vol.77
, pp. 1415-1417
-
-
Fialkow, P.J.1
Janssen, J.W.2
Bartram, C.R.3
-
10
-
-
84907225988
-
Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs
-
Boyd AL, Campbell CJ, Hopkins CI, et al. Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs. J Exp Med 2014; 211:1925-1935.
-
(2014)
J Exp Med
, vol.211
, pp. 1925-1935
-
-
Boyd, A.L.1
Campbell, C.J.2
Hopkins, C.I.3
-
11
-
-
84902200836
-
Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit
-
Medyouf H, Mossner M, Jann JC, et al. Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit. Cell Stem Cell 2014; 14:824-837.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 824-837
-
-
Medyouf, H.1
Mossner, M.2
Jann, J.C.3
-
12
-
-
84905005330
-
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
-
Arranz L, Sanchez-Aguilera A, Martin-Perez D, et al. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms. Nature 2014; 512:78-81.
-
(2014)
Nature
, vol.512
, pp. 78-81
-
-
Arranz, L.1
Sanchez-Aguilera, A.2
Martin-Perez, D.3
-
13
-
-
84902508035
-
Leukemia propagating cells rebuild an evolving niche in response to therapy
-
Duan CW, Shi J, Chen J, et al. Leukemia propagating cells rebuild an evolving niche in response to therapy. Cancer Cell 2014; 25:778-793.
-
(2014)
Cancer Cell
, vol.25
, pp. 778-793
-
-
Duan, C.W.1
Shi, J.2
Chen, J.3
-
14
-
-
57849108116
-
Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
-
Colmone A, Amorim M, Pontier AL, et al. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science 2008; 322:1861-1865.
-
(2008)
Science
, vol.322
, pp. 1861-1865
-
-
Colmone, A.1
Amorim, M.2
Pontier, A.L.3
-
15
-
-
84909594302
-
JAK2V617F-positive myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2
-
Kagoya Y, Yoshimi A, Tsuruta-Kishino T, et al. JAK2V617F-positive myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2. Blood 2014; 124:2996-3006.
-
(2014)
Blood
, vol.124
, pp. 2996-3006
-
-
Kagoya, Y.1
Yoshimi, A.2
Tsuruta-Kishino, T.3
-
16
-
-
84865827060
-
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia
-
Jan M, Snyder TM, Corces-Zimmerman MR, et al. Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med 2012; 4:149ra118.
-
(2012)
Sci Transl Med
, vol.4
, pp. 149ra118
-
-
Jan, M.1
Snyder, T.M.2
Corces-Zimmerman, M.R.3
-
17
-
-
0034691092
-
AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation
-
Miyamoto T, Weissman IL, Akashi K. AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation. Proc Natl Acad Sci U S A 2000; 97:7521-7526.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7521-7526
-
-
Miyamoto, T.1
Weissman, I.L.2
Akashi, K.3
-
18
-
-
84894304555
-
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
-
Corces-Zimmerman MR, Hong WJ, Weissman IL, et al. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A 2014; 111:2548-2553.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 2548-2553
-
-
Corces-Zimmerman, M.R.1
Hong, W.J.2
Weissman, I.L.3
-
19
-
-
84894245627
-
Identification of preleukaemic haematopoietic stem cells in acute leukaemia
-
Shlush LI, Zandi S, Mitchell A, et al. Identification of preleukaemic haematopoietic stem cells in acute leukaemia. Nature 2014; 506:328-333.
-
(2014)
Nature
, vol.506
, pp. 328-333
-
-
Shlush, L.I.1
Zandi, S.2
Mitchell, A.3
-
20
-
-
0034665776
-
Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: Evidence for involvement at the hematopoietic stem cell level
-
Nilsson L, Astrand-Grundstrom I, Arvidsson I, et al. Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level. Blood 2000; 96:2012-2021.
-
(2000)
Blood
, vol.96
, pp. 2012-2021
-
-
Nilsson, L.1
Astrand-Grundstrom, I.2
Arvidsson, I.3
-
21
-
-
84902480315
-
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
-
Woll PS, Kjallquist U, Chowdhury O, et al. Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo. Cancer Cell 2014; 25:794-808.
-
(2014)
Cancer Cell
, vol.25
, pp. 794-808
-
-
Woll, P.S.1
Kjallquist, U.2
Chowdhury, O.3
-
22
-
-
33846007215
-
Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis
-
Delhommeau F, Dupont S, Tonetti C, et al. Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis. Blood 2007; 109:71-77.
-
(2007)
Blood
, vol.109
, pp. 71-77
-
-
Delhommeau, F.1
Dupont, S.2
Tonetti, C.3
-
23
-
-
35448956762
-
Behavior of CD34+ cells isolated from patients with polycythemia vera in NOD/SCID mice
-
Ishii T, Zhao Y, Sozer S, et al. Behavior of CD34+ cells isolated from patients with polycythemia vera in NOD/SCID mice. Exp Hematol 2007; 35:1633-1640.
-
(2007)
Exp Hematol
, vol.35
, pp. 1633-1640
-
-
Ishii, T.1
Zhao, Y.2
Sozer, S.3
-
24
-
-
77955984222
-
Differential NOD/SCID mouse engraftment of peripheral blood CD34+ cells and JAK2V617F clones from patients with myeloproliferative neoplasms
-
Fung TK, Cheung AM, Kwong YL, et al. Differential NOD/SCID mouse engraftment of peripheral blood CD34+ cells and JAK2V617F clones from patients with myeloproliferative neoplasms. Leuk Res 2010; 34:1390-1394.
-
(2010)
Leuk Res
, vol.34
, pp. 1390-1394
-
-
Fung, T.K.1
Cheung, A.M.2
Kwong, Y.L.3
-
25
-
-
13544254271
-
The constitutive mobilization of bone marrow-repopulating cells into the peripheral blood in idiopathic myelofibrosis
-
Xu M, Bruno E, Chao J, et al. The constitutive mobilization of bone marrow-repopulating cells into the peripheral blood in idiopathic myelofibrosis. Blood 2005; 105:1699-1705.
-
(2005)
Blood
, vol.105
, pp. 1699-1705
-
-
Xu, M.1
Bruno, E.2
Chao, J.3
-
26
-
-
84899065964
-
Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms
-
Lundberg P, Karow A, Nienhold R, et al. Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. Blood 2014; 123:2220-2228.
-
(2014)
Blood
, vol.123
, pp. 2220-2228
-
-
Lundberg, P.1
Karow, A.2
Nienhold, R.3
-
27
-
-
34347394712
-
Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation
-
Theocharides A, Boissinot M, Girodon F, et al. Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation. Blood 2007; 110:375-379.
-
(2007)
Blood
, vol.110
, pp. 375-379
-
-
Theocharides, A.1
Boissinot, M.2
Girodon, F.3
-
28
-
-
84920268904
-
Back to biology: New insights on inheritance in myeloproliferative disorders
-
Braunstein EM, Moliterno AR. Back to biology: new insights on inheritance in myeloproliferative disorders. Curr Hematol Malig Rep 2014; 9:311-318.
-
(2014)
Curr Hematol Malig Rep
, vol.9
, pp. 311-318
-
-
Braunstein, E.M.1
Moliterno, A.R.2
-
29
-
-
84925284228
-
Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status
-
Schmidt M, Rinke J, Schafer V, et al. Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status. Leukemia 2014; 28:2292-2299.
-
(2014)
Leukemia
, vol.28
, pp. 2292-2299
-
-
Schmidt, M.1
Rinke, J.2
Schafer, V.3
-
30
-
-
84906908742
-
Acquired initiating mutations in early hematopoietic cells of CLL patients
-
Damm F, Mylonas E, Cosson A, et al. Acquired initiating mutations in early hematopoietic cells of CLL patients. Cancer Discov 2014; 4:1088-1101.
-
(2014)
Cancer Discov
, vol.4
, pp. 1088-1101
-
-
Damm, F.1
Mylonas, E.2
Cosson, A.3
-
31
-
-
84902804939
-
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia
-
Chung SS, Kim E, Park JH, et al. Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia. Sci Transl Med 2014; 6:238ra271.
-
(2014)
Sci Transl Med
, vol.6
, pp. 238ra271
-
-
Chung, S.S.1
Kim, E.2
Park, J.H.3
-
32
-
-
84895809383
-
Somatic RHOA mutation in angioimmunoblastic T cell lymphoma
-
Sakata-Yanagimoto M, Enami T, Yoshida K, et al. Somatic RHOA mutation in angioimmunoblastic T cell lymphoma. Nat Genet 2014; 46:171-175.
-
(2014)
Nat Genet
, vol.46
, pp. 171-175
-
-
Sakata-Yanagimoto, M.1
Enami, T.2
Yoshida, K.3
-
33
-
-
0001550844
-
Leukemia in Hiroshima atomic bomb survivors
-
Heyssel R, Brill AB, Woodbury LA, et al. Leukemia in Hiroshima atomic bomb survivors. Blood 1960; 15:313-331.
-
(1960)
Blood
, vol.15
, pp. 313-331
-
-
Heyssel, R.1
Brill, A.B.2
Woodbury, L.A.3
-
34
-
-
84876551509
-
Evolving risk of therapy-related acute myeloid leukemia following cancer chemotherapy among adults in the United States
-
Morton LM, Dores GM, Tucker MA, et al. Evolving risk of therapy-related acute myeloid leukemia following cancer chemotherapy among adults in the United States. Blood 2013; 121:2996-3004.
-
(2013)
Blood
, vol.121
, pp. 2996-3004
-
-
Morton, L.M.1
Dores, G.M.2
Tucker, M.A.3
-
35
-
-
84893779565
-
Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation
-
Yasuda T, Ueno T, Fukumura K, et al. Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation. Leukemia 2014; 28:426-428.
-
(2014)
Leukemia
, vol.28
, pp. 426-428
-
-
Yasuda, T.1
Ueno, T.2
Fukumura, K.3
-
36
-
-
84888019491
-
Defining stem cell dynamics in models of intestinal tumor initiation
-
Vermeulen L, Morrissey E, van der Heijden M, et al. Defining stem cell dynamics in models of intestinal tumor initiation. Science 2013; 342:995-998.
-
(2013)
Science
, vol.342
, pp. 995-998
-
-
Vermeulen, L.1
Morrissey, E.2
Van Der Heijden, M.3
-
37
-
-
84889598519
-
Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness
-
Li Q, Bohin N, Wen T, et al. Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness. Nature 2013; 504:143-147.
-
(2013)
Nature
, vol.504
, pp. 143-147
-
-
Li, Q.1
Bohin, N.2
Wen, T.3
-
38
-
-
33845415805
-
Five rules for the evolution of cooperation
-
Nowak MA. Five rules for the evolution of cooperation. Science 2006;314:1560-1563.
-
(2006)
Science
, vol.314
, pp. 1560-1563
-
-
Nowak, M.A.1
-
39
-
-
84865798159
-
Bacterial survival strategies suggest rethinking cancer cooperativity
-
Ben-Jacob E, Coffey DS, Levine H. Bacterial survival strategies suggest rethinking cancer cooperativity. Trends Microbiol 2012; 20:403-410.
-
(2012)
Trends Microbiol
, vol.20
, pp. 403-410
-
-
Ben-Jacob, E.1
Coffey, D.S.2
Levine, H.3
-
40
-
-
84886102011
-
The genetic causes of convergent evolution
-
Stern DL. The genetic causes of convergent evolution. Nat Rev Genet 2013;14:751-764.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 751-764
-
-
Stern, D.L.1
|