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Volumn 28, Issue 12, 2014, Pages 2292-2299

Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; DASATINIB; DNA METHYLTRANSFERASE 3A; IMATINIB; JANUS KINASE 2; NILOTINIB; PROTEIN P53; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR RUNX1; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR;

EID: 84925284228     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2014.272     Document Type: Article
Times cited : (116)

References (46)
  • 2
    • 0038092769 scopus 로고    scopus 로고
    • Emergence of clonal cytogenetic abnormalities in Ph-cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority
    • Bumm T, Müller C, Al-Ali HK, Krohn K, Shepherd P, Schmidt E et al. Emergence of clonal cytogenetic abnormalities in Ph-cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority. Blood 2003; 101: 1941-1949.
    • (2003) Blood , vol.101 , pp. 1941-1949
    • Bumm, T.1    Müller, C.2    Al-Ali, H.K.3    Krohn, K.4    Shepherd, P.5    Schmidt, E.6
  • 3
    • 8644286697 scopus 로고    scopus 로고
    • Clonal cytogenetic abnormalities in Philadelphia chromosome negative cells in chronic myeloid leukemia patients treated with imatinib
    • Loriaux M, Deininger M. Clonal cytogenetic abnormalities in Philadelphia chromosome negative cells in chronic myeloid leukemia patients treated with imatinib. Leuk Lymphoma 2004; 45: 2197-2203.
    • (2004) Leuk Lymphoma , vol.45 , pp. 2197-2203
    • Loriaux, M.1    Deininger, M.2
  • 4
    • 0030940742 scopus 로고    scopus 로고
    • Emergence of new clonal abnormalities following interferon-alpha induced complete cytogenetic response in patients with chronic myeloid leukemia: Report of three cases
    • Fayad L, Kantarjian H, O'Brien S, Seong D, Albitar M, Keating M et al. Emergence of new clonal abnormalities following interferon-alpha induced complete cytogenetic response in patients with chronic myeloid leukemia: report of three cases. Leukemia 1997; 11: 767-771.
    • (1997) Leukemia , vol.11 , pp. 767-771
    • Fayad, L.1    Kantarjian, H.2    O'Brien, S.3    Seong, D.4    Albitar, M.5    Keating, M.6
  • 5
    • 48749099909 scopus 로고    scopus 로고
    • Centrosome aberrations and G1 phase arrest after in vitro and in vivo treatment with the SRC/ABL inhibitor dasatinib
    • Fabarius A, Giehl M, Rebacz B, Krämer A, Frank O, Haferlach C et al. Centrosome aberrations and G1 phase arrest after in vitro and in vivo treatment with the SRC/ABL inhibitor dasatinib. Haematologica 2008; 93: 1145-1154.
    • (2008) Haematologica , vol.93 , pp. 1145-1154
    • Fabarius, A.1    Giehl, M.2    Rebacz, B.3    Krämer, A.4    Frank, O.5    Haferlach, C.6
  • 6
    • 34648833625 scopus 로고    scopus 로고
    • The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in Philadelphia chromosome-negative cells
    • Deininger MW, Cortes J, Paquette R, Park B, Hochhaus A, Baccarani M et al. The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in Philadelphia chromosome-negative cells. Cancer 2007; 110: 1509-1519.
    • (2007) Cancer , vol.110 , pp. 1509-1519
    • Deininger, M.W.1    Cortes, J.2    Paquette, R.3    Park, B.4    Hochhaus, A.5    Baccarani, M.6
  • 7
    • 35548971639 scopus 로고    scopus 로고
    • Chromosomal abnormalities in Philadelphia chromosome negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase
    • Jabbour E, Kantarjian HM, Abruzzo LV, O'Brien S, Garcia-Manero G, Verstovsek S et al. Chromosomal abnormalities in Philadelphia chromosome negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase. Blood 2007; 110: 2991-2995.
    • (2007) Blood , vol.110 , pp. 2991-2995
    • Jabbour, E.1    Kantarjian, H.M.2    Abruzzo, L.V.3    O'Brien, S.4    Garcia-Manero, G.5    Verstovsek, S.6
  • 8
    • 84869437107 scopus 로고    scopus 로고
    • The long-term clinical implications of clonal chromosomal abnormalities in newly diagnosed chronic phase chronic myeloid leukemia patients treated with imatinib mesylate
    • Lee SE, Choi SY, Bang JH, Kim SH, Jang EJ, Byeun JY et al. The long-term clinical implications of clonal chromosomal abnormalities in newly diagnosed chronic phase chronic myeloid leukemia patients treated with imatinib mesylate. Cancer Genet 2012; 205: 563-571.
    • (2012) Cancer Genet , vol.205 , pp. 563-571
    • Lee, S.E.1    Choi, S.Y.2    Bang, J.H.3    Kim, S.H.4    Jang, E.J.5    Byeun, J.Y.6
  • 9
    • 33750615550 scopus 로고    scopus 로고
    • Myelodysplastic syndromes and acute leukemia developing after imatinib mesylate therapy for chronic myeloid leukemia
    • Kovitz C, Kantarjian H, Garcia-Manero G, Abruzzo LV, Cortes J. Myelodysplastic syndromes and acute leukemia developing after imatinib mesylate therapy for chronic myeloid leukemia. Blood 2006; 108: 2811-2813.
    • (2006) Blood , vol.108 , pp. 2811-2813
    • Kovitz, C.1    Kantarjian, H.2    Garcia-Manero, G.3    Abruzzo, L.V.4    Cortes, J.5
  • 10
    • 84859627566 scopus 로고    scopus 로고
    • Development of acute myeloid leukemia with NPM1 mutation, in Ph-negative clone, during treatment of CML with imatinib
    • Georgiou G, Efthymiou A, Vardounioti I, Boutsikas G, Angelopoulou MK, Vassilakopoulos TP et al. Development of acute myeloid leukemia with NPM1 mutation, in Ph-negative clone, during treatment of CML with imatinib. Leukemia 2012; 26: 824-826.
    • (2012) Leukemia , vol.26 , pp. 824-826
    • Georgiou, G.1    Efthymiou, A.2    Vardounioti, I.3    Boutsikas, G.4    Angelopoulou, M.K.5    Vassilakopoulos, T.P.6
  • 11
    • 84881298446 scopus 로고    scopus 로고
    • European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013
    • Baccarani M, Deininger MW, Rosti G, Hochhaus A, Soverini S, Apperley JF et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood 2013; 122: 872-884.
    • (2013) Blood , vol.122 , pp. 872-884
    • Baccarani, M.1    Deininger, M.W.2    Rosti, G.3    Hochhaus, A.4    Soverini, S.5    Apperley, J.F.6
  • 13
    • 0027301905 scopus 로고
    • Further evidence for the existence of a clonal Ph-negative stage in some cases of Ph-positive chronic myelocytic leukemia
    • Raskind WH, Ferraris AM, Najfeld V, Jacobson RJ, Moohr JW, Fialkow PJ. Further evidence for the existence of a clonal Ph-negative stage in some cases of Ph-positive chronic myelocytic leukemia. Leukemia 1993; 7: 1163-1167.
    • (1993) Leukemia , vol.7 , pp. 1163-1167
    • Raskind, W.H.1    Ferraris, A.M.2    Najfeld, V.3    Jacobson, R.J.4    Moohr, J.W.5    Fialkow, P.J.6
  • 14
    • 56349129388 scopus 로고    scopus 로고
    • BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: Some common and contrasting features
    • Cross NC, Daley GQ, Green AR, Hughes TP, Jamieson C, Manley P et al. BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features. Leukemia 2008; 22: 1975-1989.
    • (2008) Leukemia , vol.22 , pp. 1975-1989
    • Cross, N.C.1    Daley, G.Q.2    Green, A.R.3    Hughes, T.P.4    Jamieson, C.5    Manley, P.6
  • 15
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 2012; 481: 506-510.
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1    Ley, T.J.2    Larson, D.E.3    Miller, C.A.4    Koboldt, D.C.5    Welch, J.S.6
  • 18
    • 84894245627 scopus 로고    scopus 로고
    • Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
    • Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V et al. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature 2014; 506: 328-333.
    • (2014) Nature , vol.506 , pp. 328-333
    • Shlush, L.I.1    Zandi, S.2    Mitchell, A.3    Chen, W.C.4    Brandwein, J.M.5    Gupta, V.6
  • 19
    • 84926991134 scopus 로고    scopus 로고
    • Pre-leukemic evolution of hematopoietic stem cells: The importance of early mutations in leukemogenesis
    • Corces-Zimmerman MR, Majeti R. Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis. Leukemia 2014; 28: 2276-2282.
    • (2014) Leukemia , vol.28 , pp. 2276-2282
    • Corces-Zimmerman, M.R.1    Majeti, R.2
  • 20
    • 78049528573 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
    • Mahon FX, Réa D, Guilhot J, Guilhot F, Huguet F, Nicolini F et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol 2010; 11: 1029-1035.
    • (2010) Lancet Oncol , vol.11 , pp. 1029-1035
    • Mahon, F.X.1    Réa, D.2    Guilhot, J.3    Guilhot, F.4    Huguet, F.5    Nicolini, F.6
  • 21
    • 84886917643 scopus 로고    scopus 로고
    • Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: Results from the TWISTER study
    • Ross DM, Branford S, Seymour JF, Schwarer AP, Arthur C, Yeung DT et al. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood 2013; 122: 515-522.
    • (2013) Blood , vol.122 , pp. 515-522
    • Ross, D.M.1    Branford, S.2    Seymour, J.F.3    Schwarer, A.P.4    Arthur, C.5    Yeung, D.T.6
  • 22
    • 40849105148 scopus 로고    scopus 로고
    • Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib
    • Ernst T, Erben P, Müller MC, Paschka P, Schenk T, Hoffmann J et al. Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib. Haematologica 2008; 93: 186-192.
    • (2008) Haematologica , vol.93 , pp. 186-192
    • Ernst, T.1    Erben, P.2    Müller, M.C.3    Paschka, P.4    Schenk, T.5    Hoffmann, J.6
  • 23
    • 84880884037 scopus 로고    scopus 로고
    • Genotyping of 25 leukemia-associated genes in a single work flow by next-generation sequencing technology with low amounts of input template DNA
    • Rinke J, Schäfer V, Schmidt M, Ziermann J, Kohlmann A, Hochhaus A et al. Genotyping of 25 leukemia-associated genes in a single work flow by next-generation sequencing technology with low amounts of input template DNA. Clin Chem 2013; 59: 1238-1250.
    • (2013) Clin Chem , vol.59 , pp. 1238-1250
    • Rinke, J.1    Schäfer, V.2    Schmidt, M.3    Ziermann, J.4    Kohlmann, A.5    Hochhaus, A.6
  • 24
    • 84867301515 scopus 로고    scopus 로고
    • Predicting the functional effect of amino acid substitutions and indels
    • Choi Y, Sims GE, Murphy S, Miller JR, Chan AP. Predicting the functional effect of amino acid substitutions and indels. PLoS ONE 2012; 7: e46688.
    • (2012) PLoS ONE , vol.7 , pp. e46688
    • Choi, Y.1    Sims, G.E.2    Murphy, S.3    Miller, J.R.4    Chan, A.P.5
  • 26
    • 85009854501 scopus 로고    scopus 로고
    • Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: A study on 350 cases
    • Schoch C, Schnittger S, Bursch S, Gerstner D, Hochhaus A, Berger U et al. Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases. Leukemia 2002; 16: 53-59.
    • (2002) Leukemia , vol.16 , pp. 53-59
    • Schoch, C.1    Schnittger, S.2    Bursch, S.3    Gerstner, D.4    Hochhaus, A.5    Berger, U.6
  • 27
    • 0027235887 scopus 로고
    • Minimal residual disease after bone marrow transplant for chronic myeloid leukaemia detected by the polymerase chain reaction
    • Cross NC, Feng L, Bungey J, Goldman JM. Minimal residual disease after bone marrow transplant for chronic myeloid leukaemia detected by the polymerase chain reaction. Leuk Lymphoma 1993; 11: 39-43.
    • (1993) Leuk Lymphoma , vol.11 , pp. 39-43
    • Cross, N.C.1    Feng, L.2    Bungey, J.3    Goldman, J.M.4
  • 28
    • 0344614012 scopus 로고    scopus 로고
    • Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR
    • Emig M, Saussele S, Wittor H, Weisser A, Reiter A, Willer A et al. Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR. Leukemia 1999; 13: 1825-1832.
    • (1999) Leukemia , vol.13 , pp. 1825-1832
    • Emig, M.1    Saussele, S.2    Wittor, H.3    Weisser, A.4    Reiter, A.5    Willer, A.6
  • 29
    • 38349081290 scopus 로고    scopus 로고
    • Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories
    • Müller MC, Erben P, Saglio G, Gottardi E, Nyvold CG, Schenk T et al. Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories. Leukemia 2008; 22: 96-102.
    • (2008) Leukemia , vol.22 , pp. 96-102
    • Müller, M.C.1    Erben, P.2    Saglio, G.3    Gottardi, E.4    Nyvold, C.G.5    Schenk, T.6
  • 30
    • 54049139246 scopus 로고    scopus 로고
    • Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trails
    • Branford S, Fletcher L, Cross NC, Müller MC, Hochhaus A, Kim D-W et al. Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trails. Blood 2008; 112: 3330-3338.
    • (2008) Blood , vol.112 , pp. 3330-3338
    • Branford, S.1    Fletcher, L.2    Cross, N.C.3    Müller, M.C.4    Hochhaus, A.5    Kim, D.-W.6
  • 32
    • 77955085750 scopus 로고    scopus 로고
    • Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
    • Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet 2010; 42: 722-726.
    • (2010) Nat Genet , vol.42 , pp. 722-726
    • Ernst, T.1    Chase, A.J.2    Score, J.3    Hidalgo-Curtis, C.E.4    Bryant, C.5    Jones, A.V.6
  • 33
    • 84866378702 scopus 로고    scopus 로고
    • The role of mutations in epigenetic regulators in myeloid malignancies
    • Shih AH, Abdel-Wahab O, Patel JP, Levine RL. The role of mutations in epigenetic regulators in myeloid malignancies. Nat Rev Cancer 2012; 12: 599-612.
    • (2012) Nat Rev Cancer , vol.12 , pp. 599-612
    • Shih, A.H.1    Abdel-Wahab, O.2    Patel, J.P.3    Levine, R.L.4
  • 34
    • 84894304555 scopus 로고    scopus 로고
    • Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
    • Corces-Zimmerman MR, Hong WJ, Weissman IL, Medeiros BC, Majeti R. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci USA 2014; 111: 2548-2553.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 2548-2553
    • Corces-Zimmerman, M.R.1    Hong, W.J.2    Weissman, I.L.3    Medeiros, B.C.4    Majeti, R.5
  • 35
    • 79960064353 scopus 로고    scopus 로고
    • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
    • Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 2011; 20: 11-24.
    • (2011) Cancer Cell , vol.20 , pp. 11-24
    • Moran-Crusio, K.1    Reavie, L.2    Shih, A.3    Abdel-Wahab, O.4    Ndiaye-Lobry, D.5    Lobry, C.6
  • 36
    • 79960062301 scopus 로고    scopus 로고
    • TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
    • Quivoron C, Couronné L, Della Valle V, Lopez CK, Plo I, Wagner-Ballon O et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 2011; 20: 25-38.
    • (2011) Cancer Cell , vol.20 , pp. 25-38
    • Quivoron, C.1    Couronné, L.2    Della Valle, V.3    Lopez, C.K.4    Plo, I.5    Wagner-Ballon, O.6
  • 37
  • 38
    • 84868208186 scopus 로고    scopus 로고
    • Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
    • Busque L, Patel JP, Figueroa ME, Vasanthakumar A, Provost S, Hamilou Z et al. Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nat Genet 2012; 44: 1179-1181.
    • (2012) Nat Genet , vol.44 , pp. 1179-1181
    • Busque, L.1    Patel, J.P.2    Figueroa, M.E.3    Vasanthakumar, A.4    Provost, S.5    Hamilou, Z.6
  • 39
    • 77956864003 scopus 로고    scopus 로고
    • Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms
    • Ernst T, Chase A, Zoi K, Waghorn K, Hidalgo-Curtis C, Score J et al. Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms. Haematologica 2010; 95: 1473-1480.
    • (2010) Haematologica , vol.95 , pp. 1473-1480
    • Ernst, T.1    Chase, A.2    Zoi, K.3    Waghorn, K.4    Hidalgo-Curtis, C.5    Score, J.6
  • 40
    • 27644592943 scopus 로고    scopus 로고
    • Coexistence of AML1/RUNX1 and BCR-ABL point mutations in an imatinibresistant form of CML
    • Corm S, Biggio V, Roche-Lestienne C, Laï JL, Yakoub-Agha I, Philippe N et al. Coexistence of AML1/RUNX1 and BCR-ABL point mutations in an imatinibresistant form of CML. Leukemia 2005; 19: 1991-1992.
    • (2005) Leukemia , vol.19 , pp. 1991-1992
    • Corm, S.1    Biggio, V.2    Roche-Lestienne, C.3    Laï, J.L.4    Yakoub-Agha, I.5    Philippe, N.6
  • 41
    • 77954583280 scopus 로고    scopus 로고
    • High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression
    • Boultwood J, Perry J, Zaman R, Fernandez-Santamaria C, Littlewood T, Kusec R et al. High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression. Leukemia 2010; 24: 1139-1145.
    • (2010) Leukemia , vol.24 , pp. 1139-1145
    • Boultwood, J.1    Perry, J.2    Zaman, R.3    Fernandez-Santamaria, C.4    Littlewood, T.5    Kusec, R.6
  • 42
    • 79952451556 scopus 로고    scopus 로고
    • A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases
    • Grossmann V, Kohlmann A, Zenger M, Schindela S, Eder C, Weissmann S et al. A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases. Leukemia 2011; 25: 557-560.
    • (2011) Leukemia , vol.25 , pp. 557-560
    • Grossmann, V.1    Kohlmann, A.2    Zenger, M.3    Schindela, S.4    Eder, C.5    Weissmann, S.6
  • 43
    • 79957593717 scopus 로고    scopus 로고
    • CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia
    • Makishima H, Jankowska AM, McDevitt MA, O'Keefe C, Dujardin S, Cazzolli H et al. CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia. Blood 2011; 117: e198-e206.
    • (2011) Blood , vol.117 , pp. e198-e206
    • Makishima, H.1    Jankowska, A.M.2    McDevitt, M.A.3    O'Keefe, C.4    Dujardin, S.5    Cazzolli, H.6
  • 44
    • 78651287826 scopus 로고    scopus 로고
    • IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis
    • Soverini S, Score J, Iacobucci I, Poerio A, Lonetti A, Gnani A et al. IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis. Leukemia 2011; 25: 178-181.
    • (2011) Leukemia , vol.25 , pp. 178-181
    • Soverini, S.1    Score, J.2    Iacobucci, I.3    Poerio, A.4    Lonetti, A.5    Gnani, A.6
  • 45
    • 84926666488 scopus 로고    scopus 로고
    • Recent advances in understanding chronic myeloid leukemia biology
    • Deininger M. Recent advances in understanding chronic myeloid leukemia biology. Hematol Edu 2013; 7: 139-146.
    • (2013) Hematol Edu , vol.7 , pp. 139-146
    • Deininger, M.1
  • 46
    • 84867405606 scopus 로고    scopus 로고
    • Standardized definitions of molecular response in chronic myeloid leukemia
    • Cross NC, White HE, Müller MC, Saglio G, Hochhaus A. Standardized definitions of molecular response in chronic myeloid leukemia. Leukemia 2012; 26: 2172-2175.
    • (2012) Leukemia , vol.26 , pp. 2172-2175
    • Cross, N.C.1    White, H.E.2    Müller, M.C.3    Saglio, G.4    Hochhaus, A.5


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