Hematopoietic Stem Cell Origin of BRAFV600E Mutations in Hairy Cell Leukemia

Science Translational Medicine

Volumn 6, Issue 238, 2014, Pages

  Chung, Stephen S ^a   Kim, Eunhee ^a   Park, Jae H ^a   Chung, Young Rock ^a   Lito, Piro ^a   Teruya Feldstein, Julie ^a   Hu, Wenhuo ^a   Beguelin, Wendy ^b   Monette, Sebastien ^c   Duy, Cihangir ^b   Rampal, Raajit ^a   Telis, Leon ^a   Patel, Minal ^a   Kim, Min Kyung ^a   Huberman, Kety ^a   Bouvier, Nancy ^a   Berger, Michael F ^a   Melnick, Ari M ^b   Rosen, Neal ^a   Tallman, Martin S ^a   Park, Christopher Y ^a,b   Abdel Wahab, Omar ^a   more..

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; VEMURAFENIB; B RAF KINASE; BRAF PROTEIN, HUMAN;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BRAF GENE; CARCINOGENESIS; CELL COMPOSITION; CELL DIFFERENTIATION; CELL RENEWAL; CLINICAL FEATURE; CLONOGENESIS; CONTROLLED STUDY; ENGRAFTMENT; GENE; GENE EXPRESSION; GENE FREQUENCY; GERMINAL CENTER; HAIRY CELL LEUKEMIA; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS; SOMATIC MUTATION; SPLENOMEGALY; THROMBOCYTOPENIA; ANIMAL; GENETICS; MUTATION; PATHOLOGY;

ANIMALS; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, HAIRY CELL; MICE; MUTATION; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 84902804939     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3008004     Document Type: Article

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