-
1
-
-
60149091189
-
Regulation of translation initiation in eukaryotes: Mechanisms and biological targets
-
Sonenberg N, Hinnebusch AG. Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell 2009;136:731-45.
-
(2009)
Cell
, vol.136
, pp. 731-745
-
-
Sonenberg, N.1
Hinnebusch, A.G.2
-
3
-
-
84858719345
-
Translational control of cell fate: From integration of environmental signals to breaching anticancer defense
-
Bitterman PB, Polunovsky VA. Translational control of cell fate: from integration of environmental signals to breaching anticancer defense. Cell Cycle 2012;11:1097-107.
-
(2012)
Cell Cycle
, vol.11
, pp. 1097-1107
-
-
Bitterman, P.B.1
Polunovsky, V.A.2
-
4
-
-
84861843696
-
A mechanistic overview of translation initiation in eukaryotes
-
Aitken CE, Lorsch JR. A mechanistic overview of translation initiation in eukaryotes. Nat Struct Mol Biol 2012;19:568-76.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 568-576
-
-
Aitken, C.E.1
Lorsch, J.R.2
-
5
-
-
70350494540
-
P53-dependent translational control of senescence and transformation via 4E-BPs
-
Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O,Martineau Y, Bidinosti M, et al. p53-dependent translational control of senescence and transformation via 4E-BPs. Cancer Cell 2009;16:439-46.
-
(2009)
Cancer Cell
, vol.16
, pp. 439-446
-
-
Petroulakis, E.1
Parsyan, A.2
Dowling, R.J.3
LeBacquer, O.4
Martineau, Y.5
Bidinosti, M.6
-
6
-
-
70350521683
-
Eukaryotic initiation factor 4E binding protein family of proteins: Sentinels at a translational control checkpoint in lung tumor defense
-
Kim YY, Von Weymarn L, Larsson O, Fan D, Underwood JM, Peterson MS, et al. Eukaryotic initiation factor 4E binding protein family of proteins: sentinels at a translational control checkpoint in lung tumor defense. Cancer Res 2009;69:8455-62.
-
(2009)
Cancer Res
, vol.69
, pp. 8455-8462
-
-
Kim, Y.Y.1
Von Weymarn, L.2
Larsson, O.3
Fan, D.4
Underwood, J.M.5
Peterson, M.S.6
-
7
-
-
0025314596
-
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 50 cap
-
Lazaris-Karatzas A, Montine KS, Sonenberg N. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 50 cap. Nature 1990;345:544-7.
-
(1990)
Nature
, vol.345
, pp. 544-547
-
-
Lazaris-Karatzas, A.1
Montine, K.S.2
Sonenberg, N.3
-
8
-
-
0030041884
-
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
-
Rousseau D, Kaspar R, Rosenwald I, Gehrke L, Sonenberg N. Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc Natl Acad Sci U S A 1996;93: 1065-70.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1065-1070
-
-
Rousseau, D.1
Kaspar, R.2
Rosenwald, I.3
Gehrke, L.4
Sonenberg, N.5
-
9
-
-
2442648845
-
The translation factor eIF-4E promotes tumor formation and cooperates with cmyc in lymphomagenesis
-
Ruggero D, Montanaro L, Ma L, Xu W, Londei P, Cordon-Cardo C, et al. The translation factor eIF-4E promotes tumor formation and cooperates with cmyc in lymphomagenesis. Nat Med 2004;10:484-6.
-
(2004)
Nat Med
, vol.10
, pp. 484-486
-
-
Ruggero, D.1
Montanaro, L.2
Ma, L.3
Xu, W.4
Londei, P.5
Cordon-Cardo, C.6
-
10
-
-
1642586272
-
Survival signalling by akt and eIF4E in oncogenesis and cancer therapy
-
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, et al. Survival signalling by akt and eIF4E in oncogenesis and cancer therapy. Nature 2004;428:332-7.
-
(2004)
Nature
, vol.428
, pp. 332-337
-
-
Wendel, H.G.1
De Stanchina, E.2
Fridman, J.S.3
Malina, A.4
Ray, S.5
Kogan, S.6
-
11
-
-
33645322443
-
Pregnancy-associated breast cancer and metastasis
-
Schedin P. Pregnancy-associated breast cancer and metastasis. Nat Rev Cancer 2006;6:281-91.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 281-291
-
-
Schedin, P.1
-
12
-
-
84857490099
-
Emerging targets for the prevention of pregnancy-associated breast cancer
-
Fornetti J, Martinson H, Borges V, Schedin P. Emerging targets for the prevention of pregnancy-associated breast cancer. Cell Cycle 2012;11: 639-40.
-
(2012)
Cell Cycle
, vol.11
, pp. 639-640
-
-
Fornetti, J.1
Martinson, H.2
Borges, V.3
Schedin, P.4
-
13
-
-
0025365397
-
Activation of ras oncogenes preceding the onset of neoplasia
-
Kumar R, Sukumar S, Barbacid M. Activation of ras oncogenes preceding the onset of neoplasia. Science 1990;248:1101-4.
-
(1990)
Science
, vol.248
, pp. 1101-1104
-
-
Kumar, R.1
Sukumar, S.2
Barbacid, M.3
-
14
-
-
9244224723
-
Intrinsic tumour suppression
-
Lowe SW, Cepero E, Evan G. Intrinsic tumour suppression. Nature 2004; 432:307-15.
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
15
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 2006;444:633-7.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
-
16
-
-
84891301320
-
Causes and consequences of replication stress
-
Zeman MK, Cimprich KA. Causes and consequences of replication stress. Nat Cell Biol 2014;16:2-9.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 2-9
-
-
Zeman, M.K.1
Cimprich, K.A.2
-
17
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997;88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
18
-
-
56849093474
-
Distinct thresholds govern myc's biological output in vivo
-
Murphy DJ, Junttila MR, Pouyet L, Karnezis A, Shchors K, Bui DA, et al. Distinct thresholds govern myc's biological output in vivo. Cancer Cell 2008;14:447-57.
-
(2008)
Cancer Cell
, vol.14
, pp. 447-457
-
-
Murphy, D.J.1
Junttila, M.R.2
Pouyet, L.3
Karnezis, A.4
Shchors, K.5
Bui, D.A.6
-
19
-
-
0037474323
-
Translation factor eIF4E rescues cells from myc-dependent apoptosis by inhibiting cytochrome c release
-
Li S, Takasu T, Perlman DM, Peterson MS, Burrichter D, Avdulov S, et al. Translation factor eIF4E rescues cells from myc-dependent apoptosis by inhibiting cytochrome c release. J Biol Chem 2003;278: 3015-22.
-
(2003)
J Biol Chem
, vol.278
, pp. 3015-3022
-
-
Li, S.1
Takasu, T.2
Perlman, D.M.3
Peterson, M.S.4
Burrichter, D.5
Avdulov, S.6
-
20
-
-
34547114029
-
Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors
-
Larsson O, Li S, Issaenko OA, Avdulov S, Peterson M, Smith K, et al. Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors. Cancer Res 2007;67:6814-24.
-
(2007)
Cancer Res
, vol.67
, pp. 6814-6824
-
-
Larsson, O.1
Li, S.2
Issaenko, O.A.3
Avdulov, S.4
Peterson, M.5
Smith, K.6
-
21
-
-
2942544833
-
Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells
-
Avdulov S, Li S, Michalek V, Burrichter D, Peterson M, Perlman DM, et al. Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells. Cancer Cell 2004;5:553-63.
-
(2004)
Cancer Cell
, vol.5
, pp. 553-563
-
-
Avdulov, S.1
Li, S.2
Michalek, V.3
Burrichter, D.4
Peterson, M.5
Perlman, D.M.6
-
22
-
-
0022255753
-
Regulation of initiation factors during translational repression caused by serum depletion. Abundance, synthesis, and turnover rates
-
Duncan R, Hershey JW. Regulation of initiation factors during translational repression caused by serum depletion. abundance, synthesis, and turnover rates. J Biol Chem 1985;260:5486-92.
-
(1985)
J Biol Chem
, vol.260
, pp. 5486-5492
-
-
Duncan, R.1
Hershey, J.W.2
-
23
-
-
0035253411
-
Cell-cycle-dependent translational control
-
Pyronnet S, Sonenberg N. Cell-cycle-dependent translational control. Curr Opin Genet Dev 2001;11:13-8.
-
(2001)
Curr Opin Genet Dev
, vol.11
, pp. 13-18
-
-
Pyronnet, S.1
Sonenberg, N.2
-
24
-
-
0036339643
-
An adjunctmammary epithelial cell population in parous females: Its role in functional adaptation and tissue renewal
-
Wagner KU, Boulanger CA, Henry MD, Sgagias M, Hennighausen L, Smith GH. An adjunctmammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal. Development 2002;129: 1377-86.
-
(2002)
Development
, vol.129
, pp. 1377-1386
-
-
Wagner, K.U.1
Boulanger, C.A.2
Henry, M.D.3
Sgagias, M.4
Hennighausen, L.5
Smith, G.H.6
-
25
-
-
4644342477
-
Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice
-
Henry MD, Triplett AA, Oh KB, Smith GH, Wagner KU. Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice. Oncogene 2004;23:6980-5.
-
(2004)
Oncogene
, vol.23
, pp. 6980-6985
-
-
Henry, M.D.1
Triplett, A.A.2
Oh, K.B.3
Smith, G.H.4
Wagner, K.U.5
-
26
-
-
22744456385
-
Epigenetic mechanisms affect mutant p53 transgene expression in WAP-mutp53 transgenic mice
-
Krepulat F, Lohler J, Heinlein C, Hermannstadter A, Tolstonog GV, Deppert W. Epigenetic mechanisms affect mutant p53 transgene expression in WAP-mutp53 transgenic mice. Oncogene 2005;24:4645-59.
-
(2005)
Oncogene
, vol.24
, pp. 4645-4659
-
-
Krepulat, F.1
Lohler, J.2
Heinlein, C.3
Hermannstadter, A.4
Tolstonog, G.V.5
Deppert, W.6
-
27
-
-
36549028297
-
Expression of truncated Int6/eIF3e inmammary alveolar epithelium leads to persistent hyperplasia and tumorigenesis
-
Mack DL, Boulanger CA, Callahan R, Smith GH. Expression of truncated Int6/eIF3e inmammary alveolar epithelium leads to persistent hyperplasia and tumorigenesis. Breast Cancer Res 2007;9:R42.
-
(2007)
Breast Cancer Res
, vol.9
, pp. R42
-
-
Mack, D.L.1
Boulanger, C.A.2
Callahan, R.3
Smith, G.H.4
-
28
-
-
0034696284
-
A transgenic mouse model for the ductal carcinoma in situ (DCIS) of themammary gland
-
Schulze-Garg C, Lohler J, Gocht A, Deppert W. A transgenic mouse model for the ductal carcinoma in situ (DCIS) of themammary gland. Oncogene 2000;19:1028-37.
-
(2000)
Oncogene
, vol.19
, pp. 1028-1037
-
-
Schulze-Garg, C.1
Lohler, J.2
Gocht, A.3
Deppert, W.4
-
29
-
-
35649001888
-
A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer
-
Braunstein S, Karpisheva K, Pola C, Goldberg J, Hochman T, Yee H, et al. A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer. Mol Cell 2007;28:501-12.
-
(2007)
Mol Cell
, vol.28
, pp. 501-512
-
-
Braunstein, S.1
Karpisheva, K.2
Pola, C.3
Goldberg, J.4
Hochman, T.5
Yee, H.6
-
30
-
-
84894267586
-
In situ identification of bipotent stem cells in the mammary gland
-
Rios AC, Fu NY, LindemanGJ, Visvader JE. In situ identification of bipotent stem cells in the mammary gland. Nature 2014;506:322-7.
-
(2014)
Nature
, vol.506
, pp. 322-327
-
-
Rios, A.C.1
Fu, N.Y.2
Lindeman, G.J.3
Visvader, J.E.4
-
31
-
-
84889598519
-
Oncogenic nras has bimodal effects on stem cells that sustainably increase competitiveness
-
Li Q, Bohin N, Wen T, Ng V, Magee J, Chen SC, et al. Oncogenic nras has bimodal effects on stem cells that sustainably increase competitiveness. Nature 2013;504:143-7.
-
(2013)
Nature
, vol.504
, pp. 143-147
-
-
Li, Q.1
Bohin, N.2
Wen, T.3
Ng, V.4
Magee, J.5
Chen, S.C.6
-
32
-
-
0037948854
-
In vitro propagation and transcriptional pro filing of humanmammary stem/progenitor cells
-
Dontu G, Abdallah WM, Foley JM, Jackson KW, ClarkeMF, KawamuraMJ, et al. In vitro propagation and transcriptional pro filing of humanmammary stem/progenitor cells. Genes Dev 2003;17:1253-70.
-
(2003)
Genes Dev
, vol.17
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
-
33
-
-
77956218241
-
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
-
Molyneux G, Geyer FC, Magnay FA, McCarthy A, Kendrick H, Natrajan R, et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 2010;7:403-17.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 403-417
-
-
Molyneux, G.1
Geyer, F.C.2
Magnay, F.A.3
McCarthy, A.4
Kendrick, H.5
Natrajan, R.6
-
34
-
-
84889563685
-
ATR prohibits replication catastrophe by preventing global exhaustion of RPA
-
Toledo LI, Altmeyer M, Rask MB, Lukas C, Larsen DH, Povlsen LK, et al. ATR prohibits replication catastrophe by preventing global exhaustion of RPA. Cell 2013;155:1088-103.
-
(2013)
Cell
, vol.155
, pp. 1088-1103
-
-
Toledo, L.I.1
Altmeyer, M.2
Rask, M.B.3
Lukas, C.4
Larsen, D.H.5
Povlsen, L.K.6
-
35
-
-
84870218588
-
DNA repair dysregulation from cancer driver to therapeutic target
-
Curtin NJ. DNA repair dysregulation from cancer driver to therapeutic target. Nat Rev Cancer 2012;12:801-17.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 801-817
-
-
Curtin, N.J.1
-
36
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, et al. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 2006;444:638-42.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
-
37
-
-
0029827631
-
Translational control of programmed cell death: Eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated myc
-
Polunovsky VA, Rosenwald IB, Tan AT, White J, Chiang L, Sonenberg N, et al. Translational control of programmed cell death: Eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated myc. Mol Cell Biol 1996;16:6573-81.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6573-6581
-
-
Polunovsky, V.A.1
Rosenwald, I.B.2
Tan, A.T.3
White, J.4
Chiang, L.5
Sonenberg, N.6
-
38
-
-
84888201853
-
The translational landscape of the mammalian cell cycle
-
Stumpf CR, Moreno MV, Olshen AB, Taylor BS, Ruggero D. The translational landscape of the mammalian cell cycle. Mol Cell 2013;52: 574-82.
-
(2013)
Mol Cell
, vol.52
, pp. 574-582
-
-
Stumpf, C.R.1
Moreno, M.V.2
Olshen, A.B.3
Taylor, B.S.4
Ruggero, D.5
-
39
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005;434: 907-13.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
-
41
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008;319: 1352-5.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
42
-
-
84901353547
-
Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer
-
Cunningham JT, Moreno MV, Lodi A, Ronen SM, Ruggero D. Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer. Cell 2014;157:1088-103.
-
(2014)
Cell
, vol.157
, pp. 1088-1103
-
-
Cunningham, J.T.1
Moreno, M.V.2
Lodi, A.3
Ronen, S.M.4
Ruggero, D.5
-
43
-
-
84862741954
-
Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation
-
Bitterman PB, Polunovsky VA. Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation. Mol Cancer Ther 2012;11:1051-61.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1051-1061
-
-
Bitterman, P.B.1
Polunovsky, V.A.2
-
44
-
-
79960839035
-
Oncogenic AKTivation of translation as a therapeutic target
-
Hsieh AC, Truitt ML, Ruggero D. Oncogenic AKTivation of translation as a therapeutic target. Br J Cancer 2011;105:329-36.
-
(2011)
Br J Cancer
, vol.105
, pp. 329-336
-
-
Hsieh, A.C.1
Truitt, M.L.2
Ruggero, D.3
-
45
-
-
84874106479
-
EIF4F suppression in breast cancer affects maintenance and progression
-
Nasr Z, Robert F, Porco JA Jr, Muller WJ, Pelletier J. eIF4F suppression in breast cancer affects maintenance and progression. Oncogene 2013;32: 861-71.
-
(2013)
Oncogene
, vol.32
, pp. 861-871
-
-
Nasr, Z.1
Robert, F.2
Porco, J.A.3
Muller, W.J.4
Pelletier, J.5
|