Cardiac-specific overexpression of melanoma differentiation-associated gene-5 protects mice from lethal viral myocarditis

Circulation: Heart Failure

Volumn 6, Issue 2, 2013, Pages 326-334

  Philip, Joseph ^a   Xu, Zhaohui ^a   Bowles, Neil E ^b   Vallejo, Jesus G ^a  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; Heart failure; Infection; Inflammation; Innate immunity; Myocardial function

Indexed keywords

BETA INTERFERON; CASPASE 3; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOPROTEIN P 15095; INTERFERON REGULATORY FACTOR 7; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; MESSENGER RNA; MYOSIN HEAVY CHAIN ALPHA; RNA HELICASE; TROPONIN I; UNCLASSIFIED DRUG; CASP3 PROTEIN, MOUSE; DEAD BOX PROTEIN; IFIH1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENCEPHALOMYOCARDITIS VIRUS; FEMALE; GENE OVEREXPRESSION; HEART FUNCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART PROTECTION; INFECTION SENSITIVITY; MALE; MOUSE; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; UPREGULATION; VIRUS LOAD; VIRUS MYOCARDITIS; VIRUS REPLICATION; ANIMAL; CARDIOVIRUS INFECTION; DISEASE MODEL; GENETICS; GENOTYPE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART STROKE VOLUME; METABOLISM; MOUSE MUTANT; MURINE ENCEPHALOMYELITIS VIRUS; MYOCARDITIS; PATHOGENICITY; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; TIME; TRANSGENIC MOUSE; VIROLOGY;

ANIMALS; APOPTOSIS; CARDIOVIRUS INFECTIONS; CASPASE 3; DEAD-BOX RNA HELICASES; DISEASE MODELS, ANIMAL; FEMALE; GENOTYPE; MALE; MAUS ELBERFELD VIRUS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MYOCARDITIS; MYOCARDIUM; PHENOTYPE; STROKE VOLUME; TIME FACTORS; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; VIRUS REPLICATION;

MLCS; MLOWN;

EID: 84877310689     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.112.969402     Document Type: Article

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