-
1
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 1989; 3: 519-526
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
2
-
-
77954385676
-
The propagation of prion-like protein inclusions in neurodegenerative diseases
-
Goedert M, Clavaguera F, Tolnay M. The propagation of prion-like protein inclusions in neurodegenerative diseases. Trends Neurosci 2010; 33: 317-325
-
(2010)
Trends Neurosci
, vol.33
, pp. 317-325
-
-
Goedert, M.1
Clavaguera, F.2
Tolnay, M.3
-
3
-
-
0030887854
-
Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments
-
Spillantini MG, Goedert M, Crowther RA, Murrell JR, Farlow MR, Ghetti B. Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proc Natl Acad Sci U S A 1997; 94: 4113-4118
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4113-4118
-
-
Spillantini, M.G.1
Goedert, M.2
Crowther, R.A.3
Murrell, J.R.4
Farlow, M.R.5
Ghetti, B.6
-
4
-
-
0026595846
-
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms
-
Goedert M, Spillantini MG, Cairns NJ, Crowther RA. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 1992; 8: 159-168
-
(1992)
Neuron
, vol.8
, pp. 159-168
-
-
Goedert, M.1
Spillantini, M.G.2
Cairns, N.J.3
Crowther, R.A.4
-
5
-
-
33751277941
-
Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): the Hisayama Study
-
Noda K, Sasaki K, Fujimi K, Wakisaka Y, Tanizaki Y, Wakugawa Y, Kiyohara Y, Iida M, Aizawa H, Iwaki T. Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): the Hisayama Study. Neuropathology 2006; 26: 508-518
-
(2006)
Neuropathology
, vol.26
, pp. 508-518
-
-
Noda, K.1
Sasaki, K.2
Fujimi, K.3
Wakisaka, Y.4
Tanizaki, Y.5
Wakugawa, Y.6
Kiyohara, Y.7
Iida, M.8
Aizawa, H.9
Iwaki, T.10
-
6
-
-
0029670872
-
Specific pathological Tau protein variants characterize Pick's disease
-
Delacourte A, Robitaille Y, Sergeant N, Buee L, Hof PR, Wattez A, Laroche-Cholette A, Mathieu J, Chagnon P, Gauvreau D. Specific pathological Tau protein variants characterize Pick's disease. J Neuropathol Exp Neurol 1996; 55: 159-168
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 159-168
-
-
Delacourte, A.1
Robitaille, Y.2
Sergeant, N.3
Buee, L.4
Hof, P.R.5
Wattez, A.6
Laroche-Cholette, A.7
Mathieu, J.8
Chagnon, P.9
Gauvreau, D.10
-
7
-
-
0025857173
-
Abnormal Tau proteins in progressive supranuclear palsy. Similarities and differences with the neurofibrillary degeneration of the Alzheimer type
-
Flament S, Delacourte A, Verny M, Hauw JJ, Javoy-Agid F. Abnormal Tau proteins in progressive supranuclear palsy. Similarities and differences with the neurofibrillary degeneration of the Alzheimer type. Acta Neuropathol 1991; 81: 591-596
-
(1991)
Acta Neuropathol
, vol.81
, pp. 591-596
-
-
Flament, S.1
Delacourte, A.2
Verny, M.3
Hauw, J.J.4
Javoy-Agid, F.5
-
8
-
-
0028091523
-
Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration
-
Ksiezak-Reding H, Morgan K, Mattiace LA, Davies P, Liu WK, Yen SH, Weidenheim K, Dickson DW. Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration. Am J Pathol 1994; 145: 1496-1508
-
(1994)
Am J Pathol
, vol.145
, pp. 1496-1508
-
-
Ksiezak-Reding, H.1
Morgan, K.2
Mattiace, L.A.3
Davies, P.4
Liu, W.K.5
Yen, S.H.6
Weidenheim, K.7
Dickson, D.W.8
-
9
-
-
0036269863
-
Argyrophilic grain disease is a sporadic 4-repeat tauopathy
-
Togo T, Sahara N, Yen SH, Cookson N, Ishizawa T, Hutton M, de Silva R, Lees A, Dickson DW. Argyrophilic grain disease is a sporadic 4-repeat tauopathy. J Neuropathol Exp Neurol 2002; 61: 547-556
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 547-556
-
-
Togo, T.1
Sahara, N.2
Yen, S.H.3
Cookson, N.4
Ishizawa, T.5
Hutton, M.6
de Silva, R.7
Lees, A.8
Dickson, D.W.9
-
10
-
-
0036938326
-
Argyrophilic grain disease and Alzheimer's disease are distinguished by their different distribution of tau protein isoforms
-
Tolnay M, Sergeant N, Ghestem A, Chalbot S, De Vos RA, Jansen Steur EN, Probst A, Delacourte A. Argyrophilic grain disease and Alzheimer's disease are distinguished by their different distribution of tau protein isoforms. Acta Neuropathol 2002; 104: 425-434
-
(2002)
Acta Neuropathol
, vol.104
, pp. 425-434
-
-
Tolnay, M.1
Sergeant, N.2
Ghestem, A.3
Chalbot, S.4
De Vos, R.A.5
Jansen Steur, E.N.6
Probst, A.7
Delacourte, A.8
-
11
-
-
0033850080
-
Abnormal tau-containing filaments in neurodegenerative diseases
-
Crowther RA, Goedert M. Abnormal tau-containing filaments in neurodegenerative diseases. J Struct Biol 2000; 130: 271-279
-
(2000)
J Struct Biol
, vol.130
, pp. 271-279
-
-
Crowther, R.A.1
Goedert, M.2
-
12
-
-
0032862488
-
Astrocytes expressing hyperphosphorylated tau protein without glial fibrillary tangles in argyrophilic grain disease
-
Botez G, Probst A, Ipsen S, Tolnay M. Astrocytes expressing hyperphosphorylated tau protein without glial fibrillary tangles in argyrophilic grain disease. Acta Neuropathol 1999; 98: 251-256
-
(1999)
Acta Neuropathol
, vol.98
, pp. 251-256
-
-
Botez, G.1
Probst, A.2
Ipsen, S.3
Tolnay, M.4
-
13
-
-
10844254688
-
Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies
-
Tolnay M, Clavaguera F. Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies. Neuropathology 2004; 24: 269-283
-
(2004)
Neuropathology
, vol.24
, pp. 269-283
-
-
Tolnay, M.1
Clavaguera, F.2
-
14
-
-
0024234435
-
Progressive supranuclear palsy: extensive neuropil threads in addition to neurofibrillary tangles. Very similar antigenicity of subcortical neuronal pathology in progressive supranuclear palsy and Alzheimer's disease
-
Probst A, Langui D, Lautenschlager C, Ulrich J, Brion JP, Anderton BH. Progressive supranuclear palsy: extensive neuropil threads in addition to neurofibrillary tangles. Very similar antigenicity of subcortical neuronal pathology in progressive supranuclear palsy and Alzheimer's disease. Acta Neuropathol 1988; 77: 61-68
-
(1988)
Acta Neuropathol
, vol.77
, pp. 61-68
-
-
Probst, A.1
Langui, D.2
Lautenschlager, C.3
Ulrich, J.4
Brion, J.P.5
Anderton, B.H.6
-
15
-
-
0026700385
-
Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy
-
Nishimura M, Namba Y, Ikeda K, Oda M. Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy. Neurosci Lett 1992; 143: 35-38
-
(1992)
Neurosci Lett
, vol.143
, pp. 35-38
-
-
Nishimura, M.1
Namba, Y.2
Ikeda, K.3
Oda, M.4
-
16
-
-
0026543843
-
Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue
-
Yamada T, McGeer PL, McGeer EG. Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue. Neurosci Lett 1992; 135: 99-102
-
(1992)
Neurosci Lett
, vol.135
, pp. 99-102
-
-
Yamada, T.1
McGeer, P.L.2
McGeer, E.G.3
-
17
-
-
0029062956
-
Widespread cytoskeletal pathology characterizes corticobasal degeneration
-
Feany MB, Dickson DW. Widespread cytoskeletal pathology characterizes corticobasal degeneration. Am J Pathol 1995; 146: 1388-1396
-
(1995)
Am J Pathol
, vol.146
, pp. 1388-1396
-
-
Feany, M.B.1
Dickson, D.W.2
-
18
-
-
0031655746
-
Astrocytic plaques and tufts of abnormal fibers do not coexist in corticobasal degeneration and progressive supranuclear palsy
-
Komori T, Arai N, Oda M, Nakayama H, Mori H, Yagishita S, Takahashi T, Amano N, Murayama S, Murakami S, Shibata N, Kobayashi M, Sasaki S, Iwata M. Astrocytic plaques and tufts of abnormal fibers do not coexist in corticobasal degeneration and progressive supranuclear palsy. Acta Neuropathol 1998; 96: 401-408
-
(1998)
Acta Neuropathol
, vol.96
, pp. 401-408
-
-
Komori, T.1
Arai, N.2
Oda, M.3
Nakayama, H.4
Mori, H.5
Yagishita, S.6
Takahashi, T.7
Amano, N.8
Murayama, S.9
Murakami, S.10
Shibata, N.11
Kobayashi, M.12
Sasaki, S.13
Iwata, M.14
-
19
-
-
0036819090
-
Frontotemporal lobar degeneration - tau as a pied piper?
-
Tolnay M, Probst A. Frontotemporal lobar degeneration - tau as a pied piper? Neurogenetics 2002; 4: 63-75
-
(2002)
Neurogenetics
, vol.4
, pp. 63-75
-
-
Tolnay, M.1
Probst, A.2
-
20
-
-
0029850476
-
Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment
-
Probst A, Tolnay M, Langui D, Goedert M, Spillantini MG. Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment. Acta Neuropathol 1996; 92: 588-596
-
(1996)
Acta Neuropathol
, vol.92
, pp. 588-596
-
-
Probst, A.1
Tolnay, M.2
Langui, D.3
Goedert, M.4
Spillantini, M.G.5
-
21
-
-
0032543684
-
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, Hackett J, Adamson J, Lincoln S, Dickson D, Davies P, Petersen RC, Stevens M, de Graaff E, Wauters E, van Baren J, Hillebrand M, Joosse M, Kwon JM, Nowotny P, Che LK, Norton J, Morris JC, Reed LA, Trojanowski J, Basun H, Lannfelt L, Neystat M, Fahn S, Dark F, Tannenberg T, Dodd PR, Hayward N, Kwok JB, Schofield PR, Andreadis A, Snowden J, Craufurd D, Neary D, Owen F, Oostra BA, Hardy J, Goate A, van Swieten J, Mann D, Lynch T, Heutink P. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 1998; 393: 702-705
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevens, M.17
de Graaff, E.18
Wauters, E.19
van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Che, L.K.25
Norton, J.26
Morris, J.C.27
Reed, L.A.28
Trojanowski, J.29
Basun, H.30
Lannfelt, L.31
Neystat, M.32
Fahn, S.33
Dark, F.34
Tannenberg, T.35
Dodd, P.R.36
Hayward, N.37
Kwok, J.B.38
Schofield, P.R.39
Andreadis, A.40
Snowden, J.41
Craufurd, D.42
Neary, D.43
Owen, F.44
Oostra, B.A.45
Hardy, J.46
Goate, A.47
van Swieten, J.48
Mann, D.49
Lynch, T.50
Heutink, P.51
more..
-
22
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia
-
Poorkaj P, Bird TD, Wijsman E, Nemens E, Garruto RM, Anderson L, Andreadis A, Wiederholt WC, Raskind M, Schellenberg GD. Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann Neurol 1998; 43: 815-825
-
(1998)
Ann Neurol
, vol.43
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
Anderson, L.6
Andreadis, A.7
Wiederholt, W.C.8
Raskind, M.9
Schellenberg, G.D.10
-
23
-
-
0031949084
-
Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies
-
Spillantini MG, Bird TD, Ghetti B. Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies. Brain Pathol 1998; 8: 387-402
-
(1998)
Brain Pathol
, vol.8
, pp. 387-402
-
-
Spillantini, M.G.1
Bird, T.D.2
Ghetti, B.3
-
24
-
-
84886590056
-
-
2nd edn. Oxford: Wiley-Blackwell
-
Ghetti B, Wsolek ZW, Boeve BF, Spina S, Goedert M. Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 2nd edn. Oxford: Wiley-Blackwell, 2011
-
(2011)
Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17
-
-
Ghetti, B.1
Wsolek, Z.W.2
Boeve, B.F.3
Spina, S.4
Goedert, M.5
-
25
-
-
0025863618
-
Neuropathological staging of Alzheimer-related changes
-
Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239-259
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
26
-
-
33749150163
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol 2006; 112: 389-404
-
(2006)
Acta Neuropathol
, vol.112
, pp. 389-404
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Del Tredici, K.5
-
27
-
-
79451471618
-
The pathological process underlying Alzheimer's disease in individuals under thirty
-
Braak H, Del Tredici K. The pathological process underlying Alzheimer's disease in individuals under thirty. Acta Neuropathol 2011; 121: 171-181
-
(2011)
Acta Neuropathol
, vol.121
, pp. 171-181
-
-
Braak, H.1
Del Tredici, K.2
-
28
-
-
4444347376
-
Staging of argyrophilic grains: an age-associated tauopathy
-
Saito Y, Ruberu NN, Sawabe M, Arai T, Tanaka N, Kakuta Y, Yamanouchi H, Murayama S. Staging of argyrophilic grains: an age-associated tauopathy. J Neuropathol Exp Neurol 2004; 63: 911-918
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 911-918
-
-
Saito, Y.1
Ruberu, N.N.2
Sawabe, M.3
Arai, T.4
Tanaka, N.5
Kakuta, Y.6
Yamanouchi, H.7
Murayama, S.8
-
29
-
-
0342803685
-
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
-
Probst A, Gotz J, Wiederhold KH, Tolnay M, Mistl C, Jaton AL, Hong M, Ishihara T, Lee VM, Trojanowski JQ, Jakes R, Crowther RA, Spillantini MG, Burki K, Goedert M. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol 2000; 99: 469-481
-
(2000)
Acta Neuropathol
, vol.99
, pp. 469-481
-
-
Probst, A.1
Gotz, J.2
Wiederhold, K.H.3
Tolnay, M.4
Mistl, C.5
Jaton, A.L.6
Hong, M.7
Ishihara, T.8
Lee, V.M.9
Trojanowski, J.Q.10
Jakes, R.11
Crowther, R.A.12
Spillantini, M.G.13
Burki, K.14
Goedert, M.15
-
30
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
Allen B, Ingram E, Takao M, Smith MJ, Jakes R, Virdee K, Yoshida H, Holzer M, Craxton M, Emson PC, Atzori C, Migheli A, Crowther RA, Ghetti B, Spillantini MG, Goedert M. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J Neurosci 2002; 22: 9340-9351
-
(2002)
J Neurosci
, vol.22
, pp. 9340-9351
-
-
Allen, B.1
Ingram, E.2
Takao, M.3
Smith, M.J.4
Jakes, R.5
Virdee, K.6
Yoshida, H.7
Holzer, M.8
Craxton, M.9
Emson, P.C.10
Atzori, C.11
Migheli, A.12
Crowther, R.A.13
Ghetti, B.14
Spillantini, M.G.15
Goedert, M.16
-
31
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol 2009; 11: 909-913
-
(2009)
Nat Cell Biol
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
Jucker, M.11
Goedert, M.12
Tolnay, M.13
-
32
-
-
84868269943
-
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
-
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Sci Rep 2012; 2: 700
-
(2012)
Sci Rep
, vol.2
, pp. 700
-
-
Lasagna-Reeves, C.A.1
Castillo-Carranza, D.L.2
Sengupta, U.3
Guerrero-Munoz, M.J.4
Kiritoshi, T.5
Neugebauer, V.6
Jackson, G.R.7
Kayed, R.8
-
33
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
De Calignon A, Polydoro M, Suarez-Calvet M, William C, Adamowicz DH, Kopeikina KJ, Pitstick R, Sahara N, Ashe KH, Carlson GA, Spires-Jones TL, Hyman BT. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron 2012; 73: 685-697
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
De Calignon, A.1
Polydoro, M.2
Suarez-Calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
Pitstick, R.7
Sahara, N.8
Ashe, K.H.9
Carlson, G.A.10
Spires-Jones, T.L.11
Hyman, B.T.12
-
34
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, Duff K. Trans-synaptic spread of tau pathology in vivo. PLoS ONE 2012; 7: e31302
-
(2012)
PLoS ONE
, vol.7
, pp. e31302
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
35
-
-
84872346089
-
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
-
Iba M, Guo JL, McBride JD, Zhang B, Trojanowski JQ, Lee VM. Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy. J Neurosci 2013; 33: 1024-1037
-
(2013)
J Neurosci
, vol.33
, pp. 1024-1037
-
-
Iba, M.1
Guo, J.L.2
McBride, J.D.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
36
-
-
84876250854
-
'Prion-like' templated misfolding in tauopathies
-
Clavaguera F, Lavenir I, Falcon B, Frank S, Goedert M, Tolnay M. 'Prion-like' templated misfolding in tauopathies. Brain Pathol 2013; 23: 342-349
-
(2013)
Brain Pathol
, vol.23
, pp. 342-349
-
-
Clavaguera, F.1
Lavenir, I.2
Falcon, B.3
Frank, S.4
Goedert, M.5
Tolnay, M.6
-
37
-
-
84899944338
-
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
-
Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, Hutton ML, O'Neill MJ. A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity. Acta Neuropathol 2014; 127: 667-683
-
(2014)
Acta Neuropathol
, vol.127
, pp. 667-683
-
-
Ahmed, Z.1
Cooper, J.2
Murray, T.K.3
Garn, K.4
McNaughton, E.5
Clarke, H.6
Parhizkar, S.7
Ward, M.A.8
Cavallini, A.9
Jackson, S.10
Bose, S.11
Clavaguera, F.12
Tolnay, M.13
Lavenir, I.14
Goedert, M.15
Hutton, M.L.16
O'Neill, M.J.17
-
38
-
-
84903541550
-
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
-
Dujardin S, Lecolle K, Caillierez R, Begard S, Zommer N, Lachaud C, Carrier S, Dufour N, Auregan G, Winderickx J, Hantraye P, Deglon N, Colin M, Buee L. Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies. Acta Neuropathol Commun 2014; 2: 14
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 14
-
-
Dujardin, S.1
Lecolle, K.2
Caillierez, R.3
Begard, S.4
Zommer, N.5
Lachaud, C.6
Carrier, S.7
Dufour, N.8
Auregan, G.9
Winderickx, J.10
Hantraye, P.11
Deglon, N.12
Colin, M.13
Buee, L.14
-
39
-
-
84896697812
-
Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice
-
Clavaguera F, Hench J, Lavenir I, Schweighauser G, Frank S, Goedert M, Tolnay M. Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice. Acta Neuropathol 2014; 127: 299-301
-
(2014)
Acta Neuropathol
, vol.127
, pp. 299-301
-
-
Clavaguera, F.1
Hench, J.2
Lavenir, I.3
Schweighauser, G.4
Frank, S.5
Goedert, M.6
Tolnay, M.7
-
40
-
-
80052940324
-
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
-
Yamada K, Cirrito JR, Stewart FR, Jiang H, Finn MB, Holmes BB, Binder LI, Mandelkow EM, Diamond MI, Lee VM, Holtzman DM. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J Neurosci 2011; 31: 13110-13117
-
(2011)
J Neurosci
, vol.31
, pp. 13110-13117
-
-
Yamada, K.1
Cirrito, J.R.2
Stewart, F.R.3
Jiang, H.4
Finn, M.B.5
Holmes, B.B.6
Binder, L.I.7
Mandelkow, E.M.8
Diamond, M.I.9
Lee, V.M.10
Holtzman, D.M.11
-
41
-
-
84876459364
-
Physiological release of endogenous tau is stimulated by neuronal activity
-
Pooler AM, Phillips EC, Lau DH, Noble W, Hanger DP. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep 2013; 14: 389-394
-
(2013)
EMBO Rep
, vol.14
, pp. 389-394
-
-
Pooler, A.M.1
Phillips, E.C.2
Lau, D.H.3
Noble, W.4
Hanger, D.P.5
-
42
-
-
84896830709
-
Neuronal activity regulates extracellular tau in vivo
-
Yamada K, Holth JK, Liao F, Stewart FR, Mahan TE, Jiang H, Cirrito JR, Patel TK, Hochgrafe K, Mandelkow EM, Holtzman DM. Neuronal activity regulates extracellular tau in vivo. J Exp Med 2014; 211: 387-393
-
(2014)
J Exp Med
, vol.211
, pp. 387-393
-
-
Yamada, K.1
Holth, J.K.2
Liao, F.3
Stewart, F.R.4
Mahan, T.E.5
Jiang, H.6
Cirrito, J.R.7
Patel, T.K.8
Hochgrafe, K.9
Mandelkow, E.M.10
Holtzman, D.M.11
-
43
-
-
84903535019
-
Ectosomes: a new mechanism for non-exosomal secretion of tau protein
-
Dujardin S, Bégard S, Caillierez R, Lachaud C, Delattre L, Carrier S, Loyens A, Galas M-C, Bousset L, Melki R, Aurégan G, Hantraye P, Brouillet E, Buée L, Colin M. Ectosomes: a new mechanism for non-exosomal secretion of tau protein. PLoS ONE 2014; 9: e100760
-
(2014)
PLoS ONE
, vol.9
, pp. e100760
-
-
Dujardin, S.1
Bégard, S.2
Caillierez, R.3
Lachaud, C.4
Delattre, L.5
Carrier, S.6
Loyens, A.7
Galas, M.-C.8
Bousset, L.9
Melki, R.10
Aurégan, G.11
Hantraye, P.12
Brouillet, E.13
Buée, L.14
Colin, M.15
-
44
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost B, Jacks RL, Diamond MI. Propagation of tau misfolding from the outside to the inside of a cell. J Biol Chem 2009; 284: 12845-12852
-
(2009)
J Biol Chem
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
45
-
-
78049376559
-
Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases
-
Nonaka T, Watanabe ST, Iwatsubo T, Hasegawa M. Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases. J Biol Chem 2010; 285: 34885-34898
-
(2010)
J Biol Chem
, vol.285
, pp. 34885-34898
-
-
Nonaka, T.1
Watanabe, S.T.2
Iwatsubo, T.3
Hasegawa, M.4
-
46
-
-
63649160214
-
Conformational diversity of wild-type Tau fibrils specified by templated conformation change
-
Frost B, Ollesch J, Wille H, Diamond MI. Conformational diversity of wild-type Tau fibrils specified by templated conformation change. J Biol Chem 2009; 284: 3546-3551
-
(2009)
J Biol Chem
, vol.284
, pp. 3546-3551
-
-
Frost, B.1
Ollesch, J.2
Wille, H.3
Diamond, M.I.4
-
47
-
-
0032428153
-
A nucleated assembly mechanism of Alzheimer paired helical filaments
-
Friedhoff P, von Bergen M, Mandelkow EM, Davies P, Mandelkow E. A nucleated assembly mechanism of Alzheimer paired helical filaments. Proc Natl Acad Sci U S A 1998; 95: 15712-15717
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15712-15717
-
-
Friedhoff, P.1
von Bergen, M.2
Mandelkow, E.M.3
Davies, P.4
Mandelkow, E.5
-
48
-
-
79955441814
-
Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles
-
Guo JL, Lee VM. Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles. J Biol Chem 2011; 286: 15317-15331
-
(2011)
J Biol Chem
, vol.286
, pp. 15317-15331
-
-
Guo, J.L.1
Lee, V.M.2
-
49
-
-
84882306577
-
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
-
Holmes BB, DeVos SL, Kfoury N, Li M, Jacks R, Yanamandra K, Ouidja MO, Brodsky FM, Marasa J, Bagchi DP, Kotzbauer PT, Miller TM, Papy-Garcia D, Diamond MI. Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds. Proc Natl Acad Sci U S A 2013; 110: E3138-3147
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. E3138-E3147
-
-
Holmes, B.B.1
DeVos, S.L.2
Kfoury, N.3
Li, M.4
Jacks, R.5
Yanamandra, K.6
Ouidja, M.O.7
Brodsky, F.M.8
Marasa, J.9
Bagchi, D.P.10
Kotzbauer, P.T.11
Miller, T.M.12
Papy-Garcia, D.13
Diamond, M.I.14
-
50
-
-
77249133010
-
Prion-like mechanisms in neurodegenerative diseases
-
Frost B, Diamond MI. Prion-like mechanisms in neurodegenerative diseases. Nat Rev Neurosci 2009; 11: 155-159
-
(2009)
Nat Rev Neurosci
, vol.11
, pp. 155-159
-
-
Frost, B.1
Diamond, M.I.2
-
51
-
-
84862003756
-
Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes
-
Santa-Maria I, Varghese M, Ksiezak-Reding H, Dzhun A, Wang J, Pasinetti GM. Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes. J Biol Chem 2012; 287: 20522-20533
-
(2012)
J Biol Chem
, vol.287
, pp. 20522-20533
-
-
Santa-Maria, I.1
Varghese, M.2
Ksiezak-Reding, H.3
Dzhun, A.4
Wang, J.5
Pasinetti, G.M.6
-
52
-
-
84878723720
-
Brain homogenates from human tauopathies induce tau inclusions in mouse brain
-
Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M, Ghetti B, Goedert M, Tolnay M. Brain homogenates from human tauopathies induce tau inclusions in mouse brain. Proc Natl Acad Sci U S A 2013; 110: 9535-9540
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 9535-9540
-
-
Clavaguera, F.1
Akatsu, H.2
Fraser, G.3
Crowther, R.A.4
Frank, S.5
Hench, J.6
Probst, A.7
Winkler, D.T.8
Reichwald, J.9
Staufenbiel, M.10
Ghetti, B.11
Goedert, M.12
Tolnay, M.13
-
53
-
-
84902486430
-
Distinct tau prion strains propagate in cells and mice and define different tauopathies
-
Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI. Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron 2014; 82: 1271-1288
-
(2014)
Neuron
, vol.82
, pp. 1271-1288
-
-
Sanders, D.W.1
Kaufman, S.K.2
DeVos, S.L.3
Sharma, A.M.4
Mirbaha, H.5
Li, A.6
Barker, S.J.7
Foley, A.C.8
Thorpe, J.R.9
Serpell, L.C.10
Miller, T.M.11
Grinberg, L.T.12
Seeley, W.W.13
Diamond, M.I.14
-
54
-
-
33750705653
-
A century of Alzheimer's disease
-
Goedert M, Spillantini MG. A century of Alzheimer's disease. Science 2006; 314: 777-781
-
(2006)
Science
, vol.314
, pp. 777-781
-
-
Goedert, M.1
Spillantini, M.G.2
-
56
-
-
0034657130
-
Evidence for seeding of beta-amyloid by intracerebral infusion of Alzheimer brain extracts in beta-amyloid precursor protein-transgenic mice
-
Kane MD, Lipinski WJ, Callahan MJ, Bian F, Durham RA, Schwarz RD, Roher AE, Walker LC. Evidence for seeding of beta-amyloid by intracerebral infusion of Alzheimer brain extracts in beta-amyloid precursor protein-transgenic mice. J Neurosci 2000; 20: 3606-3611
-
(2000)
J Neurosci
, vol.20
, pp. 3606-3611
-
-
Kane, M.D.1
Lipinski, W.J.2
Callahan, M.J.3
Bian, F.4
Durham, R.A.5
Schwarz, R.D.6
Roher, A.E.7
Walker, L.C.8
-
57
-
-
84887031600
-
Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice
-
Heilbronner G, Eisele YS, Langer F, Kaeser SA, Novotny R, Nagarathinam A, Aslund A, Hammarström P, Nilsson KPR, Jucker M. Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice. EMBO Rep 2013; 14: 1017-1022
-
(2013)
EMBO Rep
, vol.14
, pp. 1017-1022
-
-
Heilbronner, G.1
Eisele, Y.S.2
Langer, F.3
Kaeser, S.A.4
Novotny, R.5
Nagarathinam, A.6
Aslund, A.7
Hammarström, P.8
Nilsson, K.P.R.9
Jucker, M.10
-
58
-
-
84863595757
-
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions
-
Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proc Natl Acad Sci U S A 2012; 109: 11025-11030
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11025-11030
-
-
Stöhr, J.1
Watts, J.C.2
Mensinger, Z.L.3
Oehler, A.4
Grillo, S.K.5
DeArmond, S.J.6
Prusiner, S.B.7
Giles, K.8
-
59
-
-
84904333974
-
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice
-
Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice. Proc Natl Acad Sci U S A 2014; 111: 10329-10334
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 10329-10334
-
-
Stöhr, J.1
Condello, C.2
Watts, J.C.3
Bloch, L.4
Oehler, A.5
Nick, M.6
DeArmond, S.J.7
Giles, K.8
DeGrado, W.F.9
Prusiner, S.B.10
-
60
-
-
84904322386
-
Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients
-
Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proc Natl Acad Sci U S A 2014; 111: 10323-10328
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 10323-10328
-
-
Watts, J.C.1
Condello, C.2
Stöhr, J.3
Oehler, A.4
Lee, J.5
DeArmond, S.J.6
Lannfelt, L.7
Ingelsson, M.8
Giles, K.9
Prusiner, S.B.10
-
61
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Del Tredici KD, Rüb U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 2003; 24: 197-211
-
(2003)
Neurobiol Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.D.2
Rüb, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
62
-
-
84863433677
-
Prion-like acceleration of a synucleinopathy in a transgenic mouse model
-
Mougenot A-L, Nicot S, Bencsik A, Morignat E, Verchère J, Lakhdar L, Legastelois S, Baron T. Prion-like acceleration of a synucleinopathy in a transgenic mouse model. Neurobiol Aging 2012; 33: 2225-2228
-
(2012)
Neurobiol Aging
, vol.33
, pp. 2225-2228
-
-
Mougenot, A.-L.1
Nicot, S.2
Bencsik, A.3
Morignat, E.4
Verchère, J.5
Lakhdar, L.6
Legastelois, S.7
Baron, T.8
-
63
-
-
27644518721
-
Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR
-
Heise H, Hoyer W, Becker S, Andronesi OC, Riedel D, Baldus M. Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR. Proc Natl Acad Sci U S A 2005; 102: 15871-15876
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15871-15876
-
-
Heise, H.1
Hoyer, W.2
Becker, S.3
Andronesi, O.C.4
Riedel, D.5
Baldus, M.6
-
64
-
-
84892150877
-
Structural and functional characterization of two alpha-synuclein strains
-
Bousset L, Pieri L, Ruiz-Arlandis G, Gath J, Jensen PH, Habenstein B, Madiona K, Olieric V, Böckmann A, Meier BH, Melki R. Structural and functional characterization of two alpha-synuclein strains. Nat Commun 2013; 4: 2575
-
(2013)
Nat Commun
, vol.4
, pp. 2575
-
-
Bousset, L.1
Pieri, L.2
Ruiz-Arlandis, G.3
Gath, J.4
Jensen, P.H.5
Habenstein, B.6
Madiona, K.7
Olieric, V.8
Böckmann, A.9
Meier, B.H.10
Melki, R.11
-
65
-
-
84879895467
-
Distinct α-synuclein strains differentially promote tau inclusions in neurons
-
Guo JL, Covell DJ, Daniels JP, Iba M, Stieber A, Zhang B, Riddle DM, Kwong LK, Xu Y, Trojanowski JQ, Lee VMY. Distinct α-synuclein strains differentially promote tau inclusions in neurons. Cell 2013; 154: 103-117
-
(2013)
Cell
, vol.154
, pp. 103-117
-
-
Guo, J.L.1
Covell, D.J.2
Daniels, J.P.3
Iba, M.4
Stieber, A.5
Zhang, B.6
Riddle, D.M.7
Kwong, L.K.8
Xu, Y.9
Trojanowski, J.Q.10
Lee, V.M.Y.11
-
66
-
-
78149392229
-
Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis
-
Eisele YS, Obermüller U, Heilbronner G, Baumann F, Kaeser SA, Wolburg H, Walker LC, Staufenbiel M, Heikenwalder M, Jucker M. Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis. Science 2010; 330: 980-982
-
(2010)
Science
, vol.330
, pp. 980-982
-
-
Eisele, Y.S.1
Obermüller, U.2
Heilbronner, G.3
Baumann, F.4
Kaeser, S.A.5
Wolburg, H.6
Walker, L.C.7
Staufenbiel, M.8
Heikenwalder, M.9
Jucker, M.10
-
67
-
-
84905053905
-
Multiple factors contribute to the peripheral induction of cerebral β-amyloidosis
-
Eisele YS, Fritschi SK, Hamaguchi T, Obermüller U, Füger P, Skodras A, Schäfer C, Odenthal J, Heikenwalder M, Staufenbiel M, Jucker M. Multiple factors contribute to the peripheral induction of cerebral β-amyloidosis. J Neurosci 2014; 34: 10264-10273
-
(2014)
J Neurosci
, vol.34
, pp. 10264-10273
-
-
Eisele, Y.S.1
Fritschi, S.K.2
Hamaguchi, T.3
Obermüller, U.4
Füger, P.5
Skodras, A.6
Schäfer, C.7
Odenthal, J.8
Heikenwalder, M.9
Staufenbiel, M.10
Jucker, M.11
-
68
-
-
84904636970
-
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice
-
Sacino AN, Brooks M, Thomas MA, McKinney AB, Lee S, Regenhardt RW, McGarvey NH, Ayers JI, Notterpek L, Borchelt DR, Golde TE, Giasson BI. Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice. Proc Natl Acad Sci U S A 2014; 111: 10732-10737
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 10732-10737
-
-
Sacino, A.N.1
Brooks, M.2
Thomas, M.A.3
McKinney, A.B.4
Lee, S.5
Regenhardt, R.W.6
McGarvey, N.H.7
Ayers, J.I.8
Notterpek, L.9
Borchelt, D.R.10
Golde, T.E.11
Giasson, B.I.12
-
69
-
-
84922092995
-
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
-
Holmqvist S, Chutna O, Bousset L, Aldrin-Kirk P, Li W, Björklund T, Wang Z-Y, Roybon L, Melki R, Li J-Y. Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats. Acta Neuropathol 2014; 128: 805-820
-
(2014)
Acta Neuropathol
, vol.128
, pp. 805-820
-
-
Holmqvist, S.1
Chutna, O.2
Bousset, L.3
Aldrin-Kirk, P.4
Li, W.5
Björklund, T.6
Wang, Z.-Y.7
Roybon, L.8
Melki, R.9
Li, J.-Y.10
-
70
-
-
84869109864
-
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
-
Luk KC, Kehm V, Carroll J, Zhang B, O'Brien P, Trojanowski JQ, Lee VM-Y. Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. Science 2012; 338: 949-953
-
(2012)
Science
, vol.338
, pp. 949-953
-
-
Luk, K.C.1
Kehm, V.2
Carroll, J.3
Zhang, B.4
O'Brien, P.5
Trojanowski, J.Q.6
Lee, V.-Y.7
-
71
-
-
84876057762
-
Prion-like spreading of pathological α-synuclein in brain
-
Masuda-Suzukake M, Nonaka T, Hosokawa M, Oikawa T, Arai T, Akiyama H, Mann DMA, Hasegawa M. Prion-like spreading of pathological α-synuclein in brain. Brain 2013; 136: 1128-1138
-
(2013)
Brain
, vol.136
, pp. 1128-1138
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Oikawa, T.4
Arai, T.5
Akiyama, H.6
Mann, D.M.A.7
Hasegawa, M.8
-
72
-
-
84897977607
-
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
-
Recasens A, Dehay B, Bové J, Carballo-Carbajal I, Dovero S, Pérez-Villalba A, Fernagut P-O, Blesa J, Parent A, Perier C, Fariñas I, Obeso JA, Bezard E, Vila M. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann Neurol 2014; 75: 351-362
-
(2014)
Ann Neurol
, vol.75
, pp. 351-362
-
-
Recasens, A.1
Dehay, B.2
Bové, J.3
Carballo-Carbajal, I.4
Dovero, S.5
Pérez-Villalba, A.6
Fernagut, P.-O.7
Blesa, J.8
Parent, A.9
Perier, C.10
Fariñas, I.11
Obeso, J.A.12
Bezard, E.13
Vila, M.14
-
73
-
-
84908430607
-
Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
-
Peeraer E, Bottelbergs A, Van Kolen K, Stancu I-C, Vasconcelos B, Mahieu M, Duytschaever H, Ver Donck L, Torremans A, Sluydts E, Van Acker N, Kemp JA, Mercken M, Brunden KR, Trojanowski JQ, Dewachter I, Lee VMY, Moechars D. Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice. Neurobiol Dis 2014; 73C: 83-95
-
(2014)
Neurobiol Dis
, vol.73 C
, pp. 83-95
-
-
Peeraer, E.1
Bottelbergs, A.2
Van Kolen, K.3
Stancu, I.-C.4
Vasconcelos, B.5
Mahieu, M.6
Duytschaever, H.7
Ver Donck, L.8
Torremans, A.9
Sluydts, E.10
Van Acker, N.11
Kemp, J.A.12
Mercken, M.13
Brunden, K.R.14
Trojanowski, J.Q.15
Dewachter, I.16
Lee, V.M.Y.17
Moechars, D.18
-
74
-
-
65449156394
-
SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans
-
Guthrie CR, Schellenberg GD, Kraemer BC. SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans. Hum Mol Genet 2009; 18: 1825
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1825
-
-
Guthrie, C.R.1
Schellenberg, G.D.2
Kraemer, B.C.3
-
76
-
-
33646133424
-
Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans
-
Kraemer BC, Burgess JK, Chen JH, Thomas JH, Schellenberg GD. Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans. Hum Mol Genet 2006; 15: 1483
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1483
-
-
Kraemer, B.C.1
Burgess, J.K.2
Chen, J.H.3
Thomas, J.H.4
Schellenberg, G.D.5
-
77
-
-
77955972286
-
The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?
-
Wheeler JM, Guthrie CR, Kraemer BC. The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy? Biochem Soc Trans 2010; 38: 973
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 973
-
-
Wheeler, J.M.1
Guthrie, C.R.2
Kraemer, B.C.3
-
78
-
-
84873640196
-
Dopamine D2 receptor antagonism suppresses Tau aggregation and neurotoxicity
-
McCormick AV, Wheeler JM, Guthrie CR, Liachko NF, Kraemer BC. Dopamine D2 receptor antagonism suppresses Tau aggregation and neurotoxicity. Biol Psychiatry 2013; 73: 464-471
-
(2013)
Biol Psychiatry
, vol.73
, pp. 464-471
-
-
McCormick, A.V.1
Wheeler, J.M.2
Guthrie, C.R.3
Liachko, N.F.4
Kraemer, B.C.5
-
79
-
-
84923060369
-
Zinc binding directly regulates tau toxicity independent of tau hyperphosphorylation
-
Huang Y, Wu Z, Cao Y, Lang M, Lu B, Zhou B. Zinc binding directly regulates tau toxicity independent of tau hyperphosphorylation. Cell Rep 2014; 8: 831-842
-
(2014)
Cell Rep
, vol.8
, pp. 831-842
-
-
Huang, Y.1
Wu, Z.2
Cao, Y.3
Lang, M.4
Lu, B.5
Zhou, B.6
-
80
-
-
84876000270
-
Spreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegans
-
Nussbaum-Krammer CI, Park K-W, Li L, Melki R, Morimoto RI. Spreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegans. PLoS Genet 2013; 9: e1003351
-
(2013)
PLoS Genet
, vol.9
, pp. e1003351
-
-
Nussbaum-Krammer, C.I.1
Park, K.-W.2
Li, L.3
Melki, R.4
Morimoto, R.I.5
-
81
-
-
84901391350
-
Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET
-
Okamura N, Furumoto S, Fodero-Tavoletti MT, Mulligan RS, Harada R, Yates P, Pejoska S, Kudo Y, Masters CL, Yanai K, Rowe CC, Villemagne VL. Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET. Brain 2014; 137: 1762-1771
-
(2014)
Brain
, vol.137
, pp. 1762-1771
-
-
Okamura, N.1
Furumoto, S.2
Fodero-Tavoletti, M.T.3
Mulligan, R.S.4
Harada, R.5
Yates, P.6
Pejoska, S.7
Kudo, Y.8
Masters, C.L.9
Yanai, K.10
Rowe, C.C.11
Villemagne, V.L.12
-
82
-
-
84884273839
-
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls
-
Maruyama M, Shimada H, Suhara T, Shinotoh H, Ji B, Maeda J, Zhang M-R, Trojanowski JQ, Lee VM-Y, Ono M, Masamoto K, Takano H, Sahara N, Iwata N, Okamura N, Furumoto S, Kudo Y, Chang Q, Saido TC, Takashima A, Lewis J, Jang M-K, Aoki I, Ito H, Higuchi M. Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls. Neuron 2013; 79: 1094-1108
-
(2013)
Neuron
, vol.79
, pp. 1094-1108
-
-
Maruyama, M.1
Shimada, H.2
Suhara, T.3
Shinotoh, H.4
Ji, B.5
Maeda, J.6
Zhang, M.-R.7
Trojanowski, J.Q.8
Lee, V.-Y.9
Ono, M.10
Masamoto, K.11
Takano, H.12
Sahara, N.13
Iwata, N.14
Okamura, N.15
Furumoto, S.16
Kudo, Y.17
Chang, Q.18
Saido, T.C.19
Takashima, A.20
Lewis, J.21
Jang, M.-K.22
Aoki, I.23
Ito, H.24
Higuchi, M.25
more..
-
83
-
-
84865602256
-
A highly selective and specific PET tracer for imaging of tau pathologies
-
Zhang W, Arteaga J, Cashion DK, Chen G, Gangadharmath U, Gomez LF, Kasi D, Lam C, Liang Q, Liu C, Mocharla VP, Mu F, Sinha A, Szardenings AK, Wang E, Walsh JC, Xia C, Yu C, Zhao T, Kolb HC. A highly selective and specific PET tracer for imaging of tau pathologies. J Alzheimers Dis 2012; 31: 601-612
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 601-612
-
-
Zhang, W.1
Arteaga, J.2
Cashion, D.K.3
Chen, G.4
Gangadharmath, U.5
Gomez, L.F.6
Kasi, D.7
Lam, C.8
Liang, Q.9
Liu, C.10
Mocharla, V.P.11
Mu, F.12
Sinha, A.13
Szardenings, A.K.14
Wang, E.15
Walsh, J.C.16
Xia, C.17
Yu, C.18
Zhao, T.19
Kolb, H.C.20
more..
|