-
1
-
-
79958788949
-
A smouldering public-health crisis
-
Gravitz L. A smouldering public-health crisis. Nature 2011, 474:S2-S4.
-
(2011)
Nature
, vol.474
, pp. S2-S4
-
-
Gravitz, L.1
-
2
-
-
23944462641
-
Mechanism of action of interferon and ribavirin in treatment of hepatitis C
-
Feld JJ, Hoofnagle JH. Mechanism of action of interferon and ribavirin in treatment of hepatitis C. Nature 2005, 436:967-972.
-
(2005)
Nature
, vol.436
, pp. 967-972
-
-
Feld, J.J.1
Hoofnagle, J.H.2
-
3
-
-
30044432484
-
American Gastroenterological Association technical review on the management of hepatitis C
-
Dienstag JL, McHutchison JG. American Gastroenterological Association technical review on the management of hepatitis C. Gastroenterology 2006, 130:231-264.
-
(2006)
Gastroenterology
, vol.130
, pp. 231-264
-
-
Dienstag, J.L.1
McHutchison, J.G.2
-
4
-
-
77957913871
-
Discovery of a β-d-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus
-
Sofia MJ, Bao D, Chang W, Du JF, Nagarathnam D, Rachakonda S, Reddy PG, Ross BS, Wang PY, Zhang HR, et al. Discovery of a β-d-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus. J Med Chem 2010, 53:7202-7218.
-
(2010)
J Med Chem
, vol.53
, pp. 7202-7218
-
-
Sofia, M.J.1
Bao, D.2
Chang, W.3
Du, J.F.4
Nagarathnam, D.5
Rachakonda, S.6
Reddy, P.G.7
Ross, B.S.8
Wang, P.Y.9
Zhang, H.R.10
-
5
-
-
84877730954
-
Sofosbuvir for previously untreated chronic hepatitis C infection
-
Lawitz E, Mangia A, Wyles D, Rodriguez-Torres M, Hassanein T, Gordon SC, Schultz M, Davis MN, Kayali Z, Reddy KR, et al. Sofosbuvir for previously untreated chronic hepatitis C infection. New Engl J Med 2013, 368:1878-1887.
-
(2013)
New Engl J Med
, vol.368
, pp. 1878-1887
-
-
Lawitz, E.1
Mangia, A.2
Wyles, D.3
Rodriguez-Torres, M.4
Hassanein, T.5
Gordon, S.C.6
Schultz, M.7
Davis, M.N.8
Kayali, Z.9
Reddy, K.R.10
-
6
-
-
84888295678
-
Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naive genotype 1 hepatitis C: the randomized PILLAR study
-
Fried MW, Buti M, Dore GJ, Flisiak R, Ferenci P, Jacobson I, Marcellin P, Manns M, Nikitin I, Poordad F, et al. Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naive genotype 1 hepatitis C: the randomized PILLAR study. Hepatology 2013, 58:1918-1929.
-
(2013)
Hepatology
, vol.58
, pp. 1918-1929
-
-
Fried, M.W.1
Buti, M.2
Dore, G.J.3
Flisiak, R.4
Ferenci, P.5
Jacobson, I.6
Marcellin, P.7
Manns, M.8
Nikitin, I.9
Poordad, F.10
-
7
-
-
33646843732
-
SCH 503034, a mechanism-based inhibitor of hepatitis C virus (HCV) NS3 protease suppresses polyprotein maturation and enhances the antiviral activity of interferona-211 (INF)
-
Malcolm BA, Arassappan A, Bennett F, Bogen S, Chase R, Chen K, Chen T, Ingravallo P, Jao E, Kong S, et al. SCH 503034, a mechanism-based inhibitor of hepatitis C virus (HCV) NS3 protease suppresses polyprotein maturation and enhances the antiviral activity of interferona-211 (INF). Hepatology 2005, 42:535a-536a.
-
(2005)
Hepatology
, vol.42
, pp. 535a-536a
-
-
Malcolm, B.A.1
Arassappan, A.2
Bennett, F.3
Bogen, S.4
Chase, R.5
Chen, K.6
Chen, T.7
Ingravallo, P.8
Jao, E.9
Kong, S.10
-
8
-
-
33644636312
-
Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease
-
Perni RB, Almquist SJ, Byrn RA, Chandorkar G, Chaturvedi PR, Courtney LF, Decker CJ, Dinehart K, Gates CA, Harbeson SL, et al. Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease. Antimicrob Agents Chemother 2006, 50:899-909.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 899-909
-
-
Perni, R.B.1
Almquist, S.J.2
Byrn, R.A.3
Chandorkar, G.4
Chaturvedi, P.R.5
Courtney, L.F.6
Decker, C.J.7
Dinehart, K.8
Gates, C.A.9
Harbeson, S.L.10
-
9
-
-
0025968921
-
Genetic organization and diversity of the hepatitis C virus
-
Choo QL, Richman KH, Han JH, Berger K, Lee C, Dong C, Gallegos C, Coit D, Medina-Selby R, Barr PJ, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci USA 1991, 88:2451-2455.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2451-2455
-
-
Choo, Q.L.1
Richman, K.H.2
Han, J.H.3
Berger, K.4
Lee, C.5
Dong, C.6
Gallegos, C.7
Coit, D.8
Medina-Selby, R.9
Barr, P.J.10
-
10
-
-
0026084948
-
Structure and organization of the hepatitis C virus genome isolated from human carriers
-
Takamizawa A, Mori C, Fuke I, Manabe S, Murakami S, Fujita J, Onishi E, Andoh T, Yoshida I, Okayama H. Structure and organization of the hepatitis C virus genome isolated from human carriers. J Virol 1991, 65:1105-1113.
-
(1991)
J Virol
, vol.65
, pp. 1105-1113
-
-
Takamizawa, A.1
Mori, C.2
Fuke, I.3
Manabe, S.4
Murakami, S.5
Fujita, J.6
Onishi, E.7
Andoh, T.8
Yoshida, I.9
Okayama, H.10
-
11
-
-
0029949695
-
Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA
-
Honda M, Brown EA, Lemon SM. Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA. RNA 1996, 2:955-968.
-
(1996)
RNA
, vol.2
, pp. 955-968
-
-
Honda, M.1
Brown, E.A.2
Lemon, S.M.3
-
12
-
-
0031905698
-
A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs
-
Pestova TV, Shatsky IN, Fletcher SP, Jackson RJ, Hellen CU. A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs. Genes Dev 1998, 12:67-83.
-
(1998)
Genes Dev
, vol.12
, pp. 67-83
-
-
Pestova, T.V.1
Shatsky, I.N.2
Fletcher, S.P.3
Jackson, R.J.4
Hellen, C.U.5
-
13
-
-
10344243545
-
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
-
Ji H, Fraser CS, Yu YH, Leary J, Doudna JA. Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA. Proc Natl Acad Sci USA 2004, 101:16990-16995.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16990-16995
-
-
Ji, H.1
Fraser, C.S.2
Yu, Y.H.3
Leary, J.4
Doudna, J.A.5
-
14
-
-
33846959081
-
HCV and CSFVIRES domain II mediate eIF2 release during 80S ribosome assembly
-
Locker N, Easton LE, Lukavsky PJ. HCV and CSFVIRES domain II mediate eIF2 release during 80S ribosome assembly. Embo J 2007, 26:795-805.
-
(2007)
Embo J
, vol.26
, pp. 795-805
-
-
Locker, N.1
Easton, L.E.2
Lukavsky, P.J.3
-
15
-
-
0027153210
-
Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism
-
Wang C, Sarnow P, Siddiqui A. Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism. J Virol 1993, 67:3338-3344.
-
(1993)
J Virol
, vol.67
, pp. 3338-3344
-
-
Wang, C.1
Sarnow, P.2
Siddiqui, A.3
-
16
-
-
0026513651
-
Internal ribosome entry site within hepatitis-C virus-Rna
-
Tsukiyamakohara K, Iizuka N, Kohara M, Nomoto A. Internal ribosome entry site within hepatitis-C virus-Rna. J Virol 1992, 66:1476-1483.
-
(1992)
J Virol
, vol.66
, pp. 1476-1483
-
-
Tsukiyamakohara, K.1
Iizuka, N.2
Kohara, M.3
Nomoto, A.4
-
17
-
-
0026674719
-
Secondary structure of the 5′ nontranslated regions of hepatitis-C virus and pestivirus genomic Rnas
-
Brown EA, Zhang HC, Ping LH, Lemon SM. Secondary structure of the 5′ nontranslated regions of hepatitis-C virus and pestivirus genomic Rnas. Nucleic Acids Res 1992, 20:5041-5045.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 5041-5045
-
-
Brown, E.A.1
Zhang, H.C.2
Ping, L.H.3
Lemon, S.M.4
-
18
-
-
0035081519
-
Genetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virus
-
Zhao WD, Wimmer E. Genetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virus. J Virol 2001, 75:3719-3730.
-
(2001)
J Virol
, vol.75
, pp. 3719-3730
-
-
Zhao, W.D.1
Wimmer, E.2
-
19
-
-
0344628782
-
Structure of HCVIRES domain II determined by NMR
-
Lukavsky PJ, Kim I, Otto GA, Puglisi JD. Structure of HCVIRES domain II determined by NMR. Nat Struct Biol 2003, 10:1033-1038.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 1033-1038
-
-
Lukavsky, P.J.1
Kim, I.2
Otto, G.A.3
Puglisi, J.D.4
-
20
-
-
0036237981
-
Crystal structure of an RNA tertiary domain essential to HCVIRES-mediated translation initiation
-
Kieft JS, Zhou KH, Grech A, Jubin R, Doudna JA. Crystal structure of an RNA tertiary domain essential to HCVIRES-mediated translation initiation. Nat Struct Biol 2002, 9:370-374.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 370-374
-
-
Kieft, J.S.1
Zhou, K.H.2
Grech, A.3
Jubin, R.4
Doudna, J.A.5
-
21
-
-
0033673387
-
Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function
-
Lukavsky PJ, Otto GA, Lancaster AM, Sarnow P, Puglisi JD. Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function. Nat Struct Biol 2000, 7:1105-1110.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 1105-1110
-
-
Lukavsky, P.J.1
Otto, G.A.2
Lancaster, A.M.3
Sarnow, P.4
Puglisi, J.D.5
-
22
-
-
0036237498
-
A conserved RNA structure within the HCVIRES eIF3-binding site
-
Collier AJ, Gallego J, Klinck R, Cole PT, Harris SJ, Harrison GP, Aboul-ela F, Varani G, Walker S. A conserved RNA structure within the HCVIRES eIF3-binding site. Nat Struct Biol 2002, 9:375-380.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 375-380
-
-
Collier, A.J.1
Gallego, J.2
Klinck, R.3
Cole, P.T.4
Harris, S.J.5
Harrison, G.P.6
Aboul-ela, F.7
Varani, G.8
Walker, S.9
-
23
-
-
5144229241
-
Mutational and structural analysis of stem-loop IIIc of the hepatitis C virus and GB virus B internal ribosome entry sites
-
Rijnbrand R, Thiviyanathan V, Kaluarachchi K, Lemon SM, Gorenstein DG. Mutational and structural analysis of stem-loop IIIc of the hepatitis C virus and GB virus B internal ribosome entry sites. J Mol Biol 2004, 343:805-817.
-
(2004)
J Mol Biol
, vol.343
, pp. 805-817
-
-
Rijnbrand, R.1
Thiviyanathan, V.2
Kaluarachchi, K.3
Lemon, S.M.4
Gorenstein, D.G.5
-
24
-
-
80054080846
-
Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning
-
Berry KE, Waghray S, Mortimer SA, Bai Y, Doudna JA. Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning. Structure 2011, 19:1456-1466.
-
(2011)
Structure
, vol.19
, pp. 1456-1466
-
-
Berry, K.E.1
Waghray, S.2
Mortimer, S.A.3
Bai, Y.4
Doudna, J.A.5
-
25
-
-
0033600934
-
The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold
-
Kieft JS, Zhou KH, Jubin R, Murray MG, Lau JYN, Doudna JA. The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold. J Mol Biol 1999, 292:513-529.
-
(1999)
J Mol Biol
, vol.292
, pp. 513-529
-
-
Kieft, J.S.1
Zhou, K.H.2
Jubin, R.3
Murray, M.G.4
Lau, J.Y.N.5
Doudna, J.A.6
-
26
-
-
0035831269
-
Hepatitis C virus IRES RNA-induced changes in the conformation of the 40S ribosomal subunit
-
Spahn CMT, Kieft JS, Grassucci RA, Penczek PA, Zhou KH, Doudna JA, Frank J. Hepatitis C virus IRES RNA-induced changes in the conformation of the 40S ribosomal subunit. Science 2001, 291:1959-1962.
-
(2001)
Science
, vol.291
, pp. 1959-1962
-
-
Spahn, C.M.T.1
Kieft, J.S.2
Grassucci, R.A.3
Penczek, P.A.4
Zhou, K.H.5
Doudna, J.A.6
Frank, J.7
-
27
-
-
0035834686
-
Mutational analysis of the different bulge regions of hepatitis C virus domain II and their influence on internal ribosome entry site translational ability
-
Odreman-Macchioli F, Baralle FE, Buratti E. Mutational analysis of the different bulge regions of hepatitis C virus domain II and their influence on internal ribosome entry site translational ability. J Biol Chem 2001, 276:41648-41655.
-
(2001)
J Biol Chem
, vol.276
, pp. 41648-41655
-
-
Odreman-Macchioli, F.1
Baralle, F.E.2
Buratti, E.3
-
28
-
-
0037196387
-
Mutational analysis of the apical region of domain II of the HCVIRES
-
Kalliampakou KI, Psaridi-Linardaki L, Mavromara P. Mutational analysis of the apical region of domain II of the HCVIRES. Febs Lett 2002, 511:79-84.
-
(2002)
Febs Lett
, vol.511
, pp. 79-84
-
-
Kalliampakou, K.I.1
Psaridi-Linardaki, L.2
Mavromara, P.3
-
29
-
-
0033932448
-
An enzymatic footprinting analysis of the interaction of 40S ribosomal subunits with the internal ribosomal entry site of hepatitis C virus
-
Kolupaeva VG, Pestova TV, Hellen CUT. An enzymatic footprinting analysis of the interaction of 40S ribosomal subunits with the internal ribosomal entry site of hepatitis C virus. J Virol 2000, 74:6242-6250.
-
(2000)
J Virol
, vol.74
, pp. 6242-6250
-
-
Kolupaeva, V.G.1
Pestova, T.V.2
Hellen, C.U.T.3
-
30
-
-
0031901132
-
Specific interaction of eukaryotic translation initiation factor 3 with the 5′ nontranslated regions of hepatitis C virus and classical swine fever virus RNAs
-
Sizova DV, Kolupaeva VG, Pestova TV, Shatsky IN, Hellen CU. Specific interaction of eukaryotic translation initiation factor 3 with the 5′ nontranslated regions of hepatitis C virus and classical swine fever virus RNAs. J Virol 1998, 72:4775-4782.
-
(1998)
J Virol
, vol.72
, pp. 4775-4782
-
-
Sizova, D.V.1
Kolupaeva, V.G.2
Pestova, T.V.3
Shatsky, I.N.4
Hellen, C.U.5
-
31
-
-
0029016111
-
Almost the Entire 5′ Non-Translated Region of Hepatitis-C Virus Is Required for Cap-Independent Translation
-
Rijnbrand R, Bredenbeek P, Vanderstraaten T, Whetter L, Inchauspe G, Lemon S, Spaan W. Almost the Entire 5′ Non-Translated Region of Hepatitis-C Virus Is Required for Cap-Independent Translation. Febs Lett 1995, 365:115-119.
-
(1995)
Febs Lett
, vol.365
, pp. 115-119
-
-
Rijnbrand, R.1
Bredenbeek, P.2
Vanderstraaten, T.3
Whetter, L.4
Inchauspe, G.5
Lemon, S.6
Spaan, W.7
-
32
-
-
0030219426
-
Structural requirements for initiation of translation by internal ribosome entry within genome-length hepatitis C virus RNA
-
Honda M, Ping LH, Rijnbrand RCA, Amphlett E, Clarke B, Rowlands D, Lemon SM. Structural requirements for initiation of translation by internal ribosome entry within genome-length hepatitis C virus RNA. Virology 1996, 222:31-42.
-
(1996)
Virology
, vol.222
, pp. 31-42
-
-
Honda, M.1
Ping, L.H.2
Rijnbrand, R.C.A.3
Amphlett, E.4
Clarke, B.5
Rowlands, D.6
Lemon, S.M.7
-
33
-
-
0034899176
-
The ribosome binding site of hepatitis C virus mRNA
-
Lytle JR, Wu L, Robertson HD. The ribosome binding site of hepatitis C virus mRNA. J Virol 2001, 75:7629-7636.
-
(2001)
J Virol
, vol.75
, pp. 7629-7636
-
-
Lytle, J.R.1
Wu, L.2
Robertson, H.D.3
-
34
-
-
0036677165
-
Domains on the hepatitis C virus internal ribosome entry site for 40s subunit binding
-
Lytle JR, Wu L, Robertson HD. Domains on the hepatitis C virus internal ribosome entry site for 40s subunit binding. RNA 2002, 8:1045-1055.
-
(2002)
RNA
, vol.8
, pp. 1045-1055
-
-
Lytle, J.R.1
Wu, L.2
Robertson, H.D.3
-
35
-
-
77955097370
-
The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit
-
Berry KE, Waghray S, Doudna JA. The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit. RNA 2010, 16:1559-1569.
-
(2010)
RNA
, vol.16
, pp. 1559-1569
-
-
Berry, K.E.1
Waghray, S.2
Doudna, J.A.3
-
36
-
-
0035260658
-
Mechanism of ribosome recruitment by hepatitis CIRES RNA
-
Kieft JS, Zhou KH, Jubin R, Doudna JA. Mechanism of ribosome recruitment by hepatitis CIRES RNA. RNA 2001, 7:194-206.
-
(2001)
RNA
, vol.7
, pp. 194-206
-
-
Kieft, J.S.1
Zhou, K.H.2
Jubin, R.3
Doudna, J.A.4
-
37
-
-
49449093122
-
Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2
-
Terenin IM, Dmitriev SE, Andreev DE, Shatsky IN. Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2. Nat Struct Mol Biol 2008, 15:836-841.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 836-841
-
-
Terenin, I.M.1
Dmitriev, S.E.2
Andreev, D.E.3
Shatsky, I.N.4
-
38
-
-
41949130892
-
eIF2-dependent and eIF2-independent modes of initiation on the CSFVIRES: a common role of domain II
-
Pestova TV, de Breyne S, Pisarev AV, Abaeva IS, Hellen CU. eIF2-dependent and eIF2-independent modes of initiation on the CSFVIRES: a common role of domain II. Embo J 2008, 27:1060-1072.
-
(2008)
Embo J
, vol.27
, pp. 1060-1072
-
-
Pestova, T.V.1
de Breyne, S.2
Pisarev, A.V.3
Abaeva, I.S.4
Hellen, C.U.5
-
39
-
-
0032903304
-
A phylogenetically conserved stem-loop structure at the 5′ border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation
-
Honda M, Beard MR, Ping LH, Lemon SM. A phylogenetically conserved stem-loop structure at the 5′ border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation. J Virol 1999, 73:1165-1174.
-
(1999)
J Virol
, vol.73
, pp. 1165-1174
-
-
Honda, M.1
Beard, M.R.2
Ping, L.H.3
Lemon, S.M.4
-
40
-
-
33846064685
-
Functional architecture of HCVIRES domain II stabilized by divalent metal ions in the crystal and in solution
-
Dibrov SM, Johnston-Cox H, Weng YH, Hermann T. Functional architecture of HCVIRES domain II stabilized by divalent metal ions in the crystal and in solution. Angew Chem Int Ed 2007, 46:226-229.
-
(2007)
Angew Chem Int Ed
, vol.46
, pp. 226-229
-
-
Dibrov, S.M.1
Johnston-Cox, H.2
Weng, Y.H.3
Hermann, T.4
-
41
-
-
41949111249
-
Structure of hepatitis C virus IRES subdomain IIa
-
Zhao Q, Han Q, Kissinger CR, Hermann T, Thompson PA. Structure of hepatitis C virus IRES subdomain IIa. Acta Crystallogr Sect D Biol Crystallogr 2008, 64:436-443.
-
(2008)
Acta Crystallogr Sect D Biol Crystallogr
, vol.64
, pp. 436-443
-
-
Zhao, Q.1
Han, Q.2
Kissinger, C.R.3
Hermann, T.4
Thompson, P.A.5
-
42
-
-
0033019289
-
Alterations to both the primary and predicted secondary structure of stem-loop IIIc of the hepatitis C virus ib 5′ untranslated region (5′ UTR) lead to mutants severely defective in translation which cannot be complemented in trans by the wild-type 5′ UTR sequence
-
Tang SX, Collier AJ, Elliott RM. Alterations to both the primary and predicted secondary structure of stem-loop IIIc of the hepatitis C virus ib 5′ untranslated region (5′ UTR) lead to mutants severely defective in translation which cannot be complemented in trans by the wild-type 5′ UTR sequence. J Virol 1999, 73:2359-2364.
-
(1999)
J Virol
, vol.73
, pp. 2359-2364
-
-
Tang, S.X.1
Collier, A.J.2
Elliott, R.M.3
-
43
-
-
0033755598
-
Comparative analysis of translation efficiencies of hepatitis C virus 5′ untranslated regions among intraindividual quasispecies present in chronic infection: Opposite behaviors depending on cell type
-
Laporte J, Malet I, Andrieu T, Thibault V, Toulme JJ, Wychowski C, Pawlotsky JM, Huraux JM, Agut H, Cahour A. Comparative analysis of translation efficiencies of hepatitis C virus 5′ untranslated regions among intraindividual quasispecies present in chronic infection: Opposite behaviors depending on cell type. J Virol 2000, 74:10827-10833.
-
(2000)
J Virol
, vol.74
, pp. 10827-10833
-
-
Laporte, J.1
Malet, I.2
Andrieu, T.3
Thibault, V.4
Toulme, J.J.5
Wychowski, C.6
Pawlotsky, J.M.7
Huraux, J.M.8
Agut, H.9
Cahour, A.10
-
44
-
-
63349086790
-
Analysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role in cap-independent translation
-
Barria MI, Gonzalez A, Vera-Otarola J, Leon U, Vollrath V, Marsac D, Monasterio O, Perez-Acle T, Soza A, Lopez-Lastra M. Analysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role in cap-independent translation. Nucleic Acids Res 2009, 37:957-971.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 957-971
-
-
Barria, M.I.1
Gonzalez, A.2
Vera-Otarola, J.3
Leon, U.4
Vollrath, V.5
Marsac, D.6
Monasterio, O.7
Perez-Acle, T.8
Soza, A.9
Lopez-Lastra, M.10
-
45
-
-
0033744387
-
A potential RNA drug target in the hepatitis C virus internal ribosomal entry site
-
Klinck R, Westhof E, Walker S, Afshar M, Collier A, Aboul-Ela F. A potential RNA drug target in the hepatitis C virus internal ribosomal entry site. RNA 2000, 6:1423-1431.
-
(2000)
RNA
, vol.6
, pp. 1423-1431
-
-
Klinck, R.1
Westhof, E.2
Walker, S.3
Afshar, M.4
Collier, A.5
Aboul-Ela, F.6
-
46
-
-
28544443385
-
SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain
-
Seth PP, Miyaji A, Jefferson EA, Sannes-Lowery KA, Osgood SA, Propp SS, Ranken R, Massire C, Sampath R, Ecker DJ, et al. SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain. J Med Chem 2005, 48:7099-7102.
-
(2005)
J Med Chem
, vol.48
, pp. 7099-7102
-
-
Seth, P.P.1
Miyaji, A.2
Jefferson, E.A.3
Sannes-Lowery, K.A.4
Osgood, S.A.5
Propp, S.S.6
Ranken, R.7
Massire, C.8
Sampath, R.9
Ecker, D.J.10
-
47
-
-
70350347488
-
Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA
-
Parsons J, Castaldi MP, Dutta S, Dibrov SM, Wyles DL, Hermann T. Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA. Nat Chem Biol 2009, 5:823-825.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 823-825
-
-
Parsons, J.1
Castaldi, M.P.2
Dutta, S.3
Dibrov, S.M.4
Wyles, D.L.5
Hermann, T.6
-
48
-
-
77952199248
-
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
-
Paulsen RB, Seth PP, Swayze EE, Griffey RH, Skalicky JJ, Cheatham TE, Davis DR. Inhibitor-induced structural change in the HCV IRES domain IIa RNA. Proc Natl Acad Sci USA 2010, 107:7263-7268.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7263-7268
-
-
Paulsen, R.B.1
Seth, P.P.2
Swayze, E.E.3
Griffey, R.H.4
Skalicky, J.J.5
Cheatham, T.E.6
Davis, D.R.7
-
49
-
-
84859454654
-
Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches
-
Dibrov SM, Ding K, Brunn ND, Parker MA, Bergdahl BM, Wyles DL, Hermann T. Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches. Proc Natl Acad Sci USA 2012, 109:5223-5228.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 5223-5228
-
-
Dibrov, S.M.1
Ding, K.2
Brunn, N.D.3
Parker, M.A.4
Bergdahl, B.M.5
Wyles, D.L.6
Hermann, T.7
-
50
-
-
62549152278
-
Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome
-
Babaylova E, Graifer D, Malygin A, Stahl J, Shatsky I, Karpova G. Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome. Nucleic Acids Res 2009, 37:1141-1151.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1141-1151
-
-
Babaylova, E.1
Graifer, D.2
Malygin, A.3
Stahl, J.4
Shatsky, I.5
Karpova, G.6
-
51
-
-
33645804973
-
Proteins surrounding hairpin IIIe of the hepatitis C virus internal ribosome entry site on the human 40S ribosomal subunit
-
Laletina E, Graifer D, Malygin A, Ivanov A, Shatsky I, Karpova G. Proteins surrounding hairpin IIIe of the hepatitis C virus internal ribosome entry site on the human 40S ribosomal subunit. Nucleic Acids Res 2006, 34:2027-2036.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 2027-2036
-
-
Laletina, E.1
Graifer, D.2
Malygin, A.3
Ivanov, A.4
Shatsky, I.5
Karpova, G.6
-
52
-
-
0035877795
-
Ribosomal protein S5 interacts with the internal ribosomal entry site of hepatitis C virus
-
Fukushi S, Okada M, Stahl J, Kageyama T, Hoshino FB, Katayama K. Ribosomal protein S5 interacts with the internal ribosomal entry site of hepatitis C virus. J Biol Chem 2001, 276:20824-20826.
-
(2001)
J Biol Chem
, vol.276
, pp. 20824-20826
-
-
Fukushi, S.1
Okada, M.2
Stahl, J.3
Kageyama, T.4
Hoshino, F.B.5
Katayama, K.6
-
53
-
-
27644484907
-
Structure of the hepatitis C virus IRES bound to the human 80S ribosome: remodeling of the HCVIRES
-
Boehringer D, Thermann R, Ostareck-Lederer A, Lewis JD, Stark H. Structure of the hepatitis C virus IRES bound to the human 80S ribosome: remodeling of the HCVIRES. Structure 2005, 13:1695-1706.
-
(2005)
Structure
, vol.13
, pp. 1695-1706
-
-
Boehringer, D.1
Thermann, R.2
Ostareck-Lederer, A.3
Lewis, J.D.4
Stark, H.5
-
54
-
-
79959320660
-
HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit′s decoding groove
-
Filbin ME, Kieft JS. HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit′s decoding groove. RNA 2011, 17:1258-1273.
-
(2011)
RNA
, vol.17
, pp. 1258-1273
-
-
Filbin, M.E.1
Kieft, J.S.2
-
55
-
-
84873570263
-
HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation
-
Filbin ME, Vollmar BS, Shi D, Gonen T, Kieft JS. HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. Nat Struct Mol Biol 2013, 20:150-158.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 150-158
-
-
Filbin, M.E.1
Vollmar, B.S.2
Shi, D.3
Gonen, T.4
Kieft, J.S.5
-
56
-
-
7044228006
-
The pathway of HCVIRES-mediated translation initiation
-
Otto GA, Puglisi JD. The pathway of HCVIRES-mediated translation initiation. Cell 2004, 119:369-380.
-
(2004)
Cell
, vol.119
, pp. 369-380
-
-
Otto, G.A.1
Puglisi, J.D.2
-
57
-
-
26944435515
-
P-i release from elF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation
-
Algire MA, Maag D, Lorsch JR. P-i release from elF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation. Mol Cell 2005, 20:251-262.
-
(2005)
Mol Cell
, vol.20
, pp. 251-262
-
-
Algire, M.A.1
Maag, D.2
Lorsch, J.R.3
-
58
-
-
0037168583
-
Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation
-
Lee JH, Pestova TV, Shin BS, Cao C, Choi SK, Dever TE. Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation. Proc Natl Acad Sci USA 2002, 99:16689-16694.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16689-16694
-
-
Lee, J.H.1
Pestova, T.V.2
Shin, B.S.3
Cao, C.4
Choi, S.K.5
Dever, T.E.6
-
59
-
-
0033765890
-
Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding
-
Jubin R, Vantuno NE, Kieft JS, Murray MG, Doudna JA, Lau JYN, Baroudy BM. Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding. J Virol 2000, 74:10430-10437.
-
(2000)
J Virol
, vol.74
, pp. 10430-10437
-
-
Jubin, R.1
Vantuno, N.E.2
Kieft, J.S.3
Murray, M.G.4
Doudna, J.A.5
Lau, J.Y.N.6
Baroudy, B.M.7
-
60
-
-
0032126554
-
Functional analysis of the interaction between HCV 5′ UTR and putative subunits of eukaryotic translation initiation factor elF3
-
Buratti E, Tisminetzky S, Zotti M, Baralle FE. Functional analysis of the interaction between HCV 5′ UTR and putative subunits of eukaryotic translation initiation factor elF3. Nucleic Acids Res 1998, 26:3179-3187.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3179-3187
-
-
Buratti, E.1
Tisminetzky, S.2
Zotti, M.3
Baralle, F.E.4
-
61
-
-
0028151477
-
A conserved helical element is essential for internal initiation of translation of hepatitis-C virus-Rna
-
Wang CY, Sarnow P, Siddiqui A. A conserved helical element is essential for internal initiation of translation of hepatitis-C virus-Rna. J Virol 1994, 68:7301-7307.
-
(1994)
J Virol
, vol.68
, pp. 7301-7307
-
-
Wang, C.Y.1
Sarnow, P.2
Siddiqui, A.3
-
62
-
-
0031567581
-
In vivo translational efficiency of different hepatitis C virus 5′-UTRs
-
Buratti E, Gerotto M, Pontisso P, Alberti A, Tisminetzky SG, Baralle FE. In vivo translational efficiency of different hepatitis C virus 5′-UTRs. Febs Lett 1997, 411:275-280.
-
(1997)
Febs Lett
, vol.411
, pp. 275-280
-
-
Buratti, E.1
Gerotto, M.2
Pontisso, P.3
Alberti, A.4
Tisminetzky, S.G.5
Baralle, F.E.6
-
63
-
-
0033198523
-
A single nucleotide insertion in the 5′-untranslated region of hepatitis C virus leads to enhanced cap-independent translation
-
Zhang J, Yamada O, Ito T, Akiyama M, Hashimoto Y, Yoshida H, Makino R, Masago A, Uemura H, Araki H. A single nucleotide insertion in the 5′-untranslated region of hepatitis C virus leads to enhanced cap-independent translation. Virology 1999, 261:263-270.
-
(1999)
Virology
, vol.261
, pp. 263-270
-
-
Zhang, J.1
Yamada, O.2
Ito, T.3
Akiyama, M.4
Hashimoto, Y.5
Yoshida, H.6
Makino, R.7
Masago, A.8
Uemura, H.9
Araki, H.10
-
64
-
-
0038382863
-
The dynamic nature of the four-way junction of the hepatitis C virus IRES
-
Melcher SE, Wilson TJ, Lilley DMJ. The dynamic nature of the four-way junction of the hepatitis C virus IRES. RNA 2003, 9:809-820.
-
(2003)
RNA
, vol.9
, pp. 809-820
-
-
Melcher, S.E.1
Wilson, T.J.2
Lilley, D.M.J.3
-
65
-
-
84885932370
-
HCV IRES interacts with the 18S rRNA to activate the 40S ribosome for subsequent steps of translation initiation
-
Malygin AA, Kossinova OA, Shatsky IN, Karpova GG. HCV IRES interacts with the 18S rRNA to activate the 40S ribosome for subsequent steps of translation initiation. Nucleic Acids Res 2013, 41:8706-8714.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 8706-8714
-
-
Malygin, A.A.1
Kossinova, O.A.2
Shatsky, I.N.3
Karpova, G.G.4
-
66
-
-
70449717470
-
Conserved functional domains and a novel tertiary interaction near the pseudoknot drive translational activity of hepatitis C virus and hepatitis C virus-like internal ribosome entry sites
-
Easton LE, Locker N, Lukavsky PJ. Conserved functional domains and a novel tertiary interaction near the pseudoknot drive translational activity of hepatitis C virus and hepatitis C virus-like internal ribosome entry sites. Nucleic Acids Res 2009, 37:5537-5549.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 5537-5549
-
-
Easton, L.E.1
Locker, N.2
Lukavsky, P.J.3
-
67
-
-
0032782434
-
Mutational analysis of a conserved tetraloop in the 5′ untranslated region of hepatitis C virus identifies a novel RNA element essential for the internal ribosome entry site function
-
Psaridi L, Georgopoulou U, Varaklioti A, Mavromara P. Mutational analysis of a conserved tetraloop in the 5′ untranslated region of hepatitis C virus identifies a novel RNA element essential for the internal ribosome entry site function. Febs Lett 1999, 453:49-53.
-
(1999)
Febs Lett
, vol.453
, pp. 49-53
-
-
Psaridi, L.1
Georgopoulou, U.2
Varaklioti, A.3
Mavromara, P.4
-
68
-
-
0029331431
-
An Rna pseudoknot is an essential structural element of the internal ribosome entry site located within the hepatitis-C virus 5′-noncoding region
-
Wang CY, Le SY, Ali N, Siddiqui A. An Rna pseudoknot is an essential structural element of the internal ribosome entry site located within the hepatitis-C virus 5′-noncoding region. RNA 1995, 1:526-537.
-
(1995)
RNA
, vol.1
, pp. 526-537
-
-
Wang, C.Y.1
Le, S.Y.2
Ali, N.3
Siddiqui, A.4
-
69
-
-
77953669481
-
Robust and generic RNA modeling using inferred constraints: a structure for the hepatitis C virus IRES pseudoknot domain
-
Lavender CA, Ding F, Dokholyan NV, Weeks KM. Robust and generic RNA modeling using inferred constraints: a structure for the hepatitis C virus IRES pseudoknot domain. Biochemistry 2010, 49:4931-4933.
-
(2010)
Biochemistry
, vol.49
, pp. 4931-4933
-
-
Lavender, C.A.1
Ding, F.2
Dokholyan, N.V.3
Weeks, K.M.4
-
70
-
-
84875903667
-
Structure of the full-length HCV IRES in solution
-
Perard J, Leyrat C, Baudin F, Drouet E, Jamin M. Structure of the full-length HCV IRES in solution. Nat Commun 2013, 4:1612.
-
(2013)
Nat Commun
, vol.4
, pp. 1612
-
-
Perard, J.1
Leyrat, C.2
Baudin, F.3
Drouet, E.4
Jamin, M.5
-
71
-
-
0030560807
-
The influence of AUG codons in the hepatitis C virus 5′ nontranslated region on translation and mapping of the translation initiation window
-
Rijnbrand RCA, Abbink TEM, Haasnoot PCJ, Spaan WJM, Bredenbeek PJ. The influence of AUG codons in the hepatitis C virus 5′ nontranslated region on translation and mapping of the translation initiation window. Virology 1996, 226:47-56.
-
(1996)
Virology
, vol.226
, pp. 47-56
-
-
Rijnbrand, R.C.A.1
Abbink, T.E.M.2
Haasnoot, P.C.J.3
Spaan, W.J.M.4
Bredenbeek, P.J.5
-
72
-
-
0029902840
-
Internal initiation of translation of hepatitis C virus RNA: the ribosome entry site is at the authentic initiation codon
-
Reynolds JE, Kaminski A, Carroll AR, Clarke BE, Rowlands DJ, Jackson RJ. Internal initiation of translation of hepatitis C virus RNA: the ribosome entry site is at the authentic initiation codon. RNA 1996, 2:867-878.
-
(1996)
RNA
, vol.2
, pp. 867-878
-
-
Reynolds, J.E.1
Kaminski, A.2
Carroll, A.R.3
Clarke, B.E.4
Rowlands, D.J.5
Jackson, R.J.6
-
73
-
-
34347330355
-
Hepatitis C virus internal ribosome entry site initiates protein synthesis at the authentic initiation codon in yeast
-
Masek T, Vopalensky V, Horvath O, Vortelova L, Feketova Z, Pospisek M. Hepatitis C virus internal ribosome entry site initiates protein synthesis at the authentic initiation codon in yeast. J Gen Virol 2007, 88:1992-2002.
-
(2007)
J Gen Virol
, vol.88
, pp. 1992-2002
-
-
Masek, T.1
Vopalensky, V.2
Horvath, O.3
Vortelova, L.4
Feketova, Z.5
Pospisek, M.6
-
74
-
-
0028844509
-
Unique features of internal initiation of hepatitis-C virus-Rna translation
-
Reynolds JE, Kaminski A, Kettinen HJ, Grace K, Clarke BE, Carroll AR, Rowlands DJ, Jackson RJ. Unique features of internal initiation of hepatitis-C virus-Rna translation. Embo J 1995, 14:6010-6020.
-
(1995)
Embo J
, vol.14
, pp. 6010-6020
-
-
Reynolds, J.E.1
Kaminski, A.2
Kettinen, H.J.3
Grace, K.4
Clarke, B.E.5
Carroll, A.R.6
Rowlands, D.J.7
Jackson, R.J.8
-
75
-
-
0035004139
-
The influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAs
-
Rijnbrand R, Bredenbeek PJ, Haasnoot PC, Keift JS, Spaan WJM, Lemon SM. The influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAs. RNA 2001, 7:585-597.
-
(2001)
RNA
, vol.7
, pp. 585-597
-
-
Rijnbrand, R.1
Bredenbeek, P.J.2
Haasnoot, P.C.3
Keift, J.S.4
Spaan, W.J.M.5
Lemon, S.M.6
-
76
-
-
56449110274
-
Role of the hepatitis C virus core+1 open reading frame and core cis-acting RNA elements in viral RNA translation and replication
-
Vassilaki N, Friebe P, Meuleman P, Kallis S, Kaul A, Paranhos-Baccala G, Leroux-Roels G, Mavromara P, Bartenschlager R. Role of the hepatitis C virus core+1 open reading frame and core cis-acting RNA elements in viral RNA translation and replication. J Virol 2008, 82:11503-11515.
-
(2008)
J Virol
, vol.82
, pp. 11503-11515
-
-
Vassilaki, N.1
Friebe, P.2
Meuleman, P.3
Kallis, S.4
Kaul, A.5
Paranhos-Baccala, G.6
Leroux-Roels, G.7
Mavromara, P.8
Bartenschlager, R.9
-
77
-
-
0037407151
-
Long-range RNA-RNA interaction between the 5′ nontranslated region and the core-coding sequences of hepatitis C virus modulates the IRES-dependent translation
-
Kim YK, Lee SH, Kim CS, Seol SK, Jang SK. Long-range RNA-RNA interaction between the 5′ nontranslated region and the core-coding sequences of hepatitis C virus modulates the IRES-dependent translation. RNA 2003, 9:599-606.
-
(2003)
RNA
, vol.9
, pp. 599-606
-
-
Kim, Y.K.1
Lee, S.H.2
Kim, C.S.3
Seol, S.K.4
Jang, S.K.5
-
78
-
-
0034469927
-
Core protein-coding sequence, but not core protein, modulates the efficiency of cap-independent translation directed by the internal ribosome entry site of hepatitis c virus
-
Wang TH, Rijnbrand RCA, Lemon SM. Core protein-coding sequence, but not core protein, modulates the efficiency of cap-independent translation directed by the internal ribosome entry site of hepatitis c virus. J Virol 2000, 74:11347-11358.
-
(2000)
J Virol
, vol.74
, pp. 11347-11358
-
-
Wang, T.H.1
Rijnbrand, R.C.A.2
Lemon, S.M.3
-
79
-
-
58049217312
-
microRNA-122 stimulates translation of hepatitis C virus RNA
-
Henke JI, Goergen D, Zheng JF, Song YT, Schuttler CG, Fehr C, Junemann C, Niepmann M. microRNA-122 stimulates translation of hepatitis C virus RNA. Embo J 2008, 27:3300-3310.
-
(2008)
Embo J
, vol.27
, pp. 3300-3310
-
-
Henke, J.I.1
Goergen, D.2
Zheng, J.F.3
Song, Y.T.4
Schuttler, C.G.5
Fehr, C.6
Junemann, C.7
Niepmann, M.8
-
80
-
-
84863870112
-
Stimulation of Hepatitis C Virus RNA translation by microRNA-122 occurs under different conditions in vivo and in vitro
-
Goergen D, Niepmann M. Stimulation of Hepatitis C Virus RNA translation by microRNA-122 occurs under different conditions in vivo and in vitro. Virus Res 2012, 167:343-352.
-
(2012)
Virus Res
, vol.167
, pp. 343-352
-
-
Goergen, D.1
Niepmann, M.2
-
81
-
-
70449729916
-
In vitro characterization of a miR-122-sensitive double-helical switch element in the 5′ region of hepatitis C virus RNA
-
Diaz-Toledano R, Ariza-Mateos A, Birk A, Martinez-Garcia B, Gomez J. In vitro characterization of a miR-122-sensitive double-helical switch element in the 5′ region of hepatitis C virus RNA. Nucleic Acids Res 2009, 37:5498-5510.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 5498-5510
-
-
Diaz-Toledano, R.1
Ariza-Mateos, A.2
Birk, A.3
Martinez-Garcia, B.4
Gomez, J.5
-
82
-
-
34250378852
-
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry
-
Damoc E, Fraser CS, Zhou M, Videler H, Mayeur GL, Hershey JWB, Doudna JA, Robinson CV, Leary JA. Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. Mol Cell Proteomics 2007, 6:1135-1146.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 1135-1146
-
-
Damoc, E.1
Fraser, C.S.2
Zhou, M.3
Videler, H.4
Mayeur, G.L.5
Hershey, J.W.B.6
Doudna, J.A.7
Robinson, C.V.8
Leary, J.A.9
-
83
-
-
28544439977
-
Structural roles for human translation factor eIF3 in initiation of protein synthesis
-
Siridechadilok B, Fraser CS, Hall RJ, Doudna JA, Nogales E. Structural roles for human translation factor eIF3 in initiation of protein synthesis. Science 2005, 310:1513-1515.
-
(2005)
Science
, vol.310
, pp. 1513-1515
-
-
Siridechadilok, B.1
Fraser, C.S.2
Hall, R.J.3
Doudna, J.A.4
Nogales, E.5
-
84
-
-
77957222382
-
Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunit
-
Cai Q, Todorovic A, Andaya A, Gao JY, Leary JA, Cate JHD. Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunit. J Mol Biol 2010, 403:185-196.
-
(2010)
J Mol Biol
, vol.403
, pp. 185-196
-
-
Cai, Q.1
Todorovic, A.2
Andaya, A.3
Gao, J.Y.4
Leary, J.A.5
Cate, J.H.D.6
-
85
-
-
57449083256
-
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
-
Zhou M, Sandercock AM, Fraser CS, Ridlova G, Stephens E, Schenauer MR, Yokoi-Fong T, Barsky D, Leary JA, Hershey JW, et al. Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. Proc Natl Acad Sci USA 2008, 105:18139-18144.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18139-18144
-
-
Zhou, M.1
Sandercock, A.M.2
Fraser, C.S.3
Ridlova, G.4
Stephens, E.5
Schenauer, M.R.6
Yokoi-Fong, T.7
Barsky, D.8
Leary, J.A.9
Hershey, J.W.10
-
86
-
-
57749173840
-
Human initiation factor eIF3 subunit b interacts with HCV IRES RNA through its N-terminal RNA recognition motif
-
Perard J, Rasia R, Medenbach J, Ayala I, Boisbouvier J, Drouet E, Baudin F. Human initiation factor eIF3 subunit b interacts with HCV IRES RNA through its N-terminal RNA recognition motif. Febs Lett 2009, 583:70-74.
-
(2009)
Febs Lett
, vol.583
, pp. 70-74
-
-
Perard, J.1
Rasia, R.2
Medenbach, J.3
Ayala, I.4
Boisbouvier, J.5
Drouet, E.6
Baudin, F.7
-
87
-
-
64049105338
-
The pathway of hepatitis C virus mRNA recruitment to the human ribosome
-
Fraser CS, Hershey JWB, Doudna JA. The pathway of hepatitis C virus mRNA recruitment to the human ribosome. Nat Struct Mol Biol 2009, 16:397-404.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 397-404
-
-
Fraser, C.S.1
Hershey, J.W.B.2
Doudna, J.A.3
-
88
-
-
84888642485
-
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
-
Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Pestova TV, Hellen CUT, Frank J. Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit. Nature 2013, 503:539-543.
-
(2013)
Nature
, vol.503
, pp. 539-543
-
-
Hashem, Y.1
des Georges, A.2
Dhote, V.3
Langlois, R.4
Liao, H.Y.5
Grassucci, R.A.6
Pestova, T.V.7
Hellen, C.U.T.8
Frank, J.9
-
89
-
-
84883477130
-
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
-
Sun C, Querol-Audi J, Mortimer SA, Arias-Palomo E, Doudna JA, Nogales E, Cate JH. Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation. Nucleic Acids Res 2013, 41:7512-7521.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 7512-7521
-
-
Sun, C.1
Querol-Audi, J.2
Mortimer, S.A.3
Arias-Palomo, E.4
Doudna, J.A.5
Nogales, E.6
Cate, J.H.7
-
90
-
-
75149139029
-
Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation
-
Garaigorta U, Chisari FV. Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation. Cell Host Microbe 2009, 6:513-522.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 513-522
-
-
Garaigorta, U.1
Chisari, F.V.2
-
91
-
-
68249108671
-
Translational insensitivity to potent activation of PKR by HCV IRES RNA
-
Shimoike T, McKenna SA, Lindhout DA, Puglisi JD. Translational insensitivity to potent activation of PKR by HCV IRES RNA. Antiviral Res 2009, 83:228-237.
-
(2009)
Antiviral Res
, vol.83
, pp. 228-237
-
-
Shimoike, T.1
McKenna, S.A.2
Lindhout, D.A.3
Puglisi, J.D.4
-
92
-
-
77954384495
-
Regulation of PKR by HCV IRES RNA: importance of domain II and NS5A
-
Toroney R, Nallagatla SR, Boyer JA, Cameron CE, Bevilacqua PC. Regulation of PKR by HCV IRES RNA: importance of domain II and NS5A. J Mol Biol 2010, 400:393-412.
-
(2010)
J Mol Biol
, vol.400
, pp. 393-412
-
-
Toroney, R.1
Nallagatla, S.R.2
Boyer, J.A.3
Cameron, C.E.4
Bevilacqua, P.C.5
-
93
-
-
0034688313
-
The joining of ribosomal subunits in eukaryotes requires eIF5B
-
Pestova TV, Lomakin IB, Lee JH, Choi SK, Dever TE, Hellen CUT. The joining of ribosomal subunits in eukaryotes requires eIF5B. Nature 2000, 403:332-335.
-
(2000)
Nature
, vol.403
, pp. 332-335
-
-
Pestova, T.V.1
Lomakin, I.B.2
Lee, J.H.3
Choi, S.K.4
Dever, T.E.5
Hellen, C.U.T.6
-
94
-
-
10644249220
-
Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP
-
Unbehaun A, Borukhov SI, Hellen CUT, Pestova TV. Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP. Genes Dev 2004, 18:3078-3093.
-
(2004)
Genes Dev
, vol.18
, pp. 3078-3093
-
-
Unbehaun, A.1
Borukhov, S.I.2
Hellen, C.U.T.3
Pestova, T.V.4
-
95
-
-
0034703718
-
X-ray structures of the universal translation initiation factor IF2/elF5B: conformational changes on GDP and GTP binding
-
Roll-Mecak A, Cao C, Dever TE, Burley SK. X-ray structures of the universal translation initiation factor IF2/elF5B: conformational changes on GDP and GTP binding. Cell 2000, 103:781-792.
-
(2000)
Cell
, vol.103
, pp. 781-792
-
-
Roll-Mecak, A.1
Cao, C.2
Dever, T.E.3
Burley, S.K.4
-
96
-
-
79958804665
-
eIF2A mediates translation of hepatitis C viral mRNA under stress conditions
-
Kim JH, Park SM, Park JH, Keum SJ, Jang SK. eIF2A mediates translation of hepatitis C viral mRNA under stress conditions. Embo J 2011, 30:2454-2464.
-
(2011)
Embo J
, vol.30
, pp. 2454-2464
-
-
Kim, J.H.1
Park, S.M.2
Park, J.H.3
Keum, S.J.4
Jang, S.K.5
-
97
-
-
77956245342
-
GTP-independent tRNA delivery to the ribosomal P-site by a novel eukaryotic translation factor
-
Dmitriev SE, Terenin IM, Andreev DE, Ivanov PA, Dunaevsky JE, Merrick WC, Shatsky IN. GTP-independent tRNA delivery to the ribosomal P-site by a novel eukaryotic translation factor. J Biol Chem 2010, 285:26779-26787.
-
(2010)
J Biol Chem
, vol.285
, pp. 26779-26787
-
-
Dmitriev, S.E.1
Terenin, I.M.2
Andreev, D.E.3
Ivanov, P.A.4
Dunaevsky, J.E.5
Merrick, W.C.6
Shatsky, I.N.7
-
98
-
-
33750532939
-
Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2 center dot GTP center dot Met-tRNA(i)(Met) ternary complex availability
-
Robert F, Kapp LD, Khan SN, Acker MG, Kolitz S, Kazemi S, Kaufman RJ, Merrick WC, Koromilas AE, Lorsch JR, et al. Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2 center dot GTP center dot Met-tRNA(i)(Met) ternary complex availability. Mol Biol Cell 2006, 17:4632-4644.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 4632-4644
-
-
Robert, F.1
Kapp, L.D.2
Khan, S.N.3
Acker, M.G.4
Kolitz, S.5
Kazemi, S.6
Kaufman, R.J.7
Merrick, W.C.8
Koromilas, A.E.9
Lorsch, J.R.10
-
99
-
-
33646186734
-
Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry site
-
Lancaster AM, Jan E, Sarnow P. Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry site. RNA 2006, 12:894-902.
-
(2006)
RNA
, vol.12
, pp. 894-902
-
-
Lancaster, A.M.1
Jan, E.2
Sarnow, P.3
-
100
-
-
84923005601
-
-
a database of mutations within the IRES of the hepatitis C virus.
-
HCVIVdb.org (http://www.hcvivdb.org/), a database of mutations within the IRES of the hepatitis C virus.
-
-
-
|