-
1
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
Wang E.T., Sandberg R., Luo S., Khrebtukova I., Zhang L., Mayr C., et al. Alternative isoform regulation in human tissue transcriptomes. Nature 2008, 456:470-476.
-
(2008)
Nature
, vol.456
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
Khrebtukova, I.4
Zhang, L.5
Mayr, C.6
-
2
-
-
84865812140
-
Genomics. ENCODE project writes eulogy for junk DNA
-
Pennisi E. Genomics. ENCODE project writes eulogy for junk DNA. Science 2012, 337:1159-1161.
-
(2012)
Science
, vol.337
, pp. 1159-1161
-
-
Pennisi, E.1
-
3
-
-
0037023384
-
A draft sequence of the rice genome (Oryza sativa L. ssp. indica)
-
Yu J., Hu S., Wang J., Wong G.K., Li S., Liu B., et al. A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science 2002, 296:79-92.
-
(2002)
Science
, vol.296
, pp. 79-92
-
-
Yu, J.1
Hu, S.2
Wang, J.3
Wong, G.K.4
Li, S.5
Liu, B.6
-
4
-
-
70350569286
-
Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
-
Chen M., Manley J.L. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat Rev Mol Cell Biol 2009, 10:741-754.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 741-754
-
-
Chen, M.1
Manley, J.L.2
-
5
-
-
77953677503
-
Heart failure-associated changes in RNA splicing of sarcomere genes
-
Kong S.W., Hu Y.W., Ho J.W., Ikeda S., Polster S., John R., et al. Heart failure-associated changes in RNA splicing of sarcomere genes. Circ Cardiovasc Genet 2010, 3:138-146.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, pp. 138-146
-
-
Kong, S.W.1
Hu, Y.W.2
Ho, J.W.3
Ikeda, S.4
Polster, S.5
John, R.6
-
6
-
-
68949191192
-
Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy
-
Brauch K.M., Karst M.L., Herron K.J., de Andrade M., Pellikka P.A., Rodeheffer R.J., et al. Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy. J Am Coll Cardiol 2009, 54:930-941.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 930-941
-
-
Brauch, K.M.1
Karst, M.L.2
Herron, K.J.3
de Andrade, M.4
Pellikka, P.A.5
Rodeheffer, R.J.6
-
7
-
-
84860667942
-
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
-
Guo W., Schafer S., Greaser M.L., Radke M.H., Liss M., Govindarajan T., et al. RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing. Nat Med 2012, 18:766-773.
-
(2012)
Nat Med
, vol.18
, pp. 766-773
-
-
Guo, W.1
Schafer, S.2
Greaser, M.L.3
Radke, M.H.4
Liss, M.5
Govindarajan, T.6
-
8
-
-
58149492467
-
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
-
Kalsotra A., Xiao X., Ward A.J., Castle J.C., Johnson J.M., Burge C.B., et al. A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci U S A 2008, 105:20333-20338.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20333-20338
-
-
Kalsotra, A.1
Xiao, X.2
Ward, A.J.3
Castle, J.C.4
Johnson, J.M.5
Burge, C.B.6
-
9
-
-
19944427655
-
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle
-
Xu X., Yang D., Ding J.H., Wang W., Chu P.H., Dalton N.D., et al. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell 2005, 120:59-72.
-
(2005)
Cell
, vol.120
, pp. 59-72
-
-
Xu, X.1
Yang, D.2
Ding, J.H.3
Wang, W.4
Chu, P.H.5
Dalton, N.D.6
-
10
-
-
1242281665
-
Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium
-
Lahmers S., Wu Y., Call D.R., Labeit S., Granzier H. Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium. Circ Res 2004, 94:505-513.
-
(2004)
Circ Res
, vol.94
, pp. 505-513
-
-
Lahmers, S.1
Wu, Y.2
Call, D.R.3
Labeit, S.4
Granzier, H.5
-
11
-
-
1842830381
-
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart
-
Opitz C.A., Leake M.C., Makarenko I., Benes V., Linke W.A. Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart. Circ Res 2004, 94:967-975.
-
(2004)
Circ Res
, vol.94
, pp. 967-975
-
-
Opitz, C.A.1
Leake, M.C.2
Makarenko, I.3
Benes, V.4
Linke, W.A.5
-
12
-
-
5344277512
-
Titin isoform changes in rat myocardium during development
-
Warren C.M., Krzesinski P.R., Campbell K.S., Moss R.L., Greaser M.L. Titin isoform changes in rat myocardium during development. Mech Dev 2004, 121:1301-1312.
-
(2004)
Mech Dev
, vol.121
, pp. 1301-1312
-
-
Warren, C.M.1
Krzesinski, P.R.2
Campbell, K.S.3
Moss, R.L.4
Greaser, M.L.5
-
13
-
-
84880955708
-
Sequencing of mRNA identifies re-expression of fetal splice variants in cardiac hypertrophy
-
Ames E.G., Lawson M.J., Mackey A.J., Holmes J.W. Sequencing of mRNA identifies re-expression of fetal splice variants in cardiac hypertrophy. J Mol Cell Cardiol 2013, 62:99-107.
-
(2013)
J Mol Cell Cardiol
, vol.62
, pp. 99-107
-
-
Ames, E.G.1
Lawson, M.J.2
Mackey, A.J.3
Holmes, J.W.4
-
14
-
-
84907976655
-
RBM24 is a major regulator of muscle-specific alternative splicing
-
Yang J., Hung L.-H., Licht T., Kostin S., Looso M., Khrameeva E., et al. RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell 2014, 31:87-99.
-
(2014)
Dev Cell
, vol.31
, pp. 87-99
-
-
Yang, J.1
Hung, L.-H.2
Licht, T.3
Kostin, S.4
Looso, M.5
Khrameeva, E.6
-
15
-
-
18544406997
-
Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity
-
Freiburg A., Trombitas K., Hell W., Cazorla O., Fougerousse F., Centner T., et al. Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity. Circ Res 2000, 86:1114-1121.
-
(2000)
Circ Res
, vol.86
, pp. 1114-1121
-
-
Freiburg, A.1
Trombitas, K.2
Hell, W.3
Cazorla, O.4
Fougerousse, F.5
Centner, T.6
-
16
-
-
0035941407
-
The complete gene sequence of titin, expression of an unusual 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system
-
Bang M.L., Centner T., Fornoff F., Geach A.J., Gotthardt M., McNabb M., et al. The complete gene sequence of titin, expression of an unusual 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system. Circ Res 2001, 89:1065-1072.
-
(2001)
Circ Res
, vol.89
, pp. 1065-1072
-
-
Bang, M.L.1
Centner, T.2
Fornoff, F.3
Geach, A.J.4
Gotthardt, M.5
McNabb, M.6
-
17
-
-
0028824480
-
Titins: giant proteins in charge of muscle ultrastructure and elasticity
-
Labeit S., Kolmerer B. Titins: giant proteins in charge of muscle ultrastructure and elasticity. Science 1995, 270:293-296.
-
(1995)
Science
, vol.270
, pp. 293-296
-
-
Labeit, S.1
Kolmerer, B.2
-
18
-
-
0028957373
-
Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments
-
Granzier H.L., Irving T.C. Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments. Biophys J 1995, 68:1027-1044.
-
(1995)
Biophys J
, vol.68
, pp. 1027-1044
-
-
Granzier, H.L.1
Irving, T.C.2
-
19
-
-
0029823455
-
Titin develops restoring force in rat cardiac myocytes
-
Helmes M., Trombitas K., Granzier H. Titin develops restoring force in rat cardiac myocytes. Circ Res 1996, 79:619-626.
-
(1996)
Circ Res
, vol.79
, pp. 619-626
-
-
Helmes, M.1
Trombitas, K.2
Granzier, H.3
-
20
-
-
33745698385
-
Restoring force development by titin/connectin and assessment of Ig domain unfolding
-
Preetha N., Yiming W., Helmes M., Norio F., Siegfried L., Granzier H. Restoring force development by titin/connectin and assessment of Ig domain unfolding. J Muscle Res Cell Motil 2005, 26:307-317.
-
(2005)
J Muscle Res Cell Motil
, vol.26
, pp. 307-317
-
-
Preetha, N.1
Yiming, W.2
Helmes, M.3
Norio, F.4
Siegfried, L.5
Granzier, H.6
-
21
-
-
0034786066
-
Cardiac titin isoforms are coexpressed in the half-sarcomere and extend independently
-
Trombitas K., Wu Y., Labeit D., Labeit S., Granzier H. Cardiac titin isoforms are coexpressed in the half-sarcomere and extend independently. Am J Physiol Heart Circ Physiol 2001, 281:H1793-H1799.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.281
, pp. H1793-H1799
-
-
Trombitas, K.1
Wu, Y.2
Labeit, D.3
Labeit, S.4
Granzier, H.5
-
22
-
-
0344896768
-
Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle
-
Fukuda N., Wu Y., Farman G., Irving T.C., Granzier H. Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle. J Physiol 2003, 553:147-154.
-
(2003)
J Physiol
, vol.553
, pp. 147-154
-
-
Fukuda, N.1
Wu, Y.2
Farman, G.3
Irving, T.C.4
Granzier, H.5
-
23
-
-
0037056083
-
Titin isoform switch in ischemic human heart disease
-
Neagoe C., Kulke M., del Monte F., Gwathmey J.K., de Tombe P.P., Hajjar R.J., et al. Titin isoform switch in ischemic human heart disease. Circulation 2002, 106:1333-1341.
-
(2002)
Circulation
, vol.106
, pp. 1333-1341
-
-
Neagoe, C.1
Kulke, M.2
del Monte, F.3
Gwathmey, J.K.4
de Tombe, P.P.5
Hajjar, R.J.6
-
24
-
-
4944235675
-
Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts
-
Makarenko I., Opitz C.A., Leake M.C., Neagoe C., Kulke M., Gwathmey J.K., et al. Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts. Circ Res 2004, 95:708-716.
-
(2004)
Circ Res
, vol.95
, pp. 708-716
-
-
Makarenko, I.1
Opitz, C.A.2
Leake, M.C.3
Neagoe, C.4
Kulke, M.5
Gwathmey, J.K.6
-
25
-
-
3142672018
-
Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy
-
Nagueh S.F., Shah G., Wu Y., Torre-Amione G., King N.M., Lahmers S., et al. Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy. Circulation 2004, 110:155-162.
-
(2004)
Circulation
, vol.110
, pp. 155-162
-
-
Nagueh, S.F.1
Shah, G.2
Wu, Y.3
Torre-Amione, G.4
King, N.M.5
Lahmers, S.6
-
26
-
-
84901480223
-
Experimentally increasing titin compliance in a novel mouse model attenuates the frank-starling mechanism but has a beneficial effect on diastole
-
Methawasin M., Hutchinson K.R., Lee E.J., Smith J.E., Saripalli C., Hidalgo C.G., et al. Experimentally increasing titin compliance in a novel mouse model attenuates the frank-starling mechanism but has a beneficial effect on diastole. Circulation 2014, 129:1924-1936.
-
(2014)
Circulation
, vol.129
, pp. 1924-1936
-
-
Methawasin, M.1
Hutchinson, K.R.2
Lee, E.J.3
Smith, J.E.4
Saripalli, C.5
Hidalgo, C.G.6
-
27
-
-
84876353525
-
Rbm20 regulates titin alternative splicing as a splicing repressor
-
Li S., Guo W., Dewey C.N., Greaser M.L. Rbm20 regulates titin alternative splicing as a splicing repressor. Nucleic Acids Res 2013, 41:2659-2672.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 2659-2672
-
-
Li, S.1
Guo, W.2
Dewey, C.N.3
Greaser, M.L.4
-
28
-
-
84905460023
-
RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing
-
Maatz H., Jens M., Liss M., Schafer S., Heinig M., Kirchner M., et al. RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing. J Clin Invest 2014, 124:3419-3430.
-
(2014)
J Clin Invest
, vol.124
, pp. 3419-3430
-
-
Maatz, H.1
Jens, M.2
Liss, M.3
Schafer, S.4
Heinig, M.5
Kirchner, M.6
-
29
-
-
84862777447
-
Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy
-
Refaat M.M., Lubitz S.A., Makino S., Islam Z., Frangiskakis J.M., Mehdi H., et al. Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy. Heart Rhythm 2012, 9:390-396.
-
(2012)
Heart Rhythm
, vol.9
, pp. 390-396
-
-
Refaat, M.M.1
Lubitz, S.A.2
Makino, S.3
Islam, Z.4
Frangiskakis, J.M.5
Mehdi, H.6
-
30
-
-
84929617783
-
Atlas of the clinical genetics of human dilated cardiomyopathy
-
Haas J., Frese K.S., Peil B., Kloos W., Keller A., Nietsch R., et al. Atlas of the clinical genetics of human dilated cardiomyopathy. Eur Heart J 2014.
-
(2014)
Eur Heart J
-
-
Haas, J.1
Frese, K.S.2
Peil, B.3
Kloos, W.4
Keller, A.5
Nietsch, R.6
-
31
-
-
84874476580
-
Titin is a major human disease gene
-
LeWinter M.M., Granzier H.L. Titin is a major human disease gene. Circulation 2013, 127:938-944.
-
(2013)
Circulation
, vol.127
, pp. 938-944
-
-
LeWinter, M.M.1
Granzier, H.L.2
-
32
-
-
45349086526
-
Physiological functions of the giant elastic protein titin in mammalian striated muscle
-
Fukuda N., Granzier H.L., Ishiwata S., Kurihara S. Physiological functions of the giant elastic protein titin in mammalian striated muscle. J Physiol Sci 2008, 58:151-159.
-
(2008)
J Physiol Sci
, vol.58
, pp. 151-159
-
-
Fukuda, N.1
Granzier, H.L.2
Ishiwata, S.3
Kurihara, S.4
-
33
-
-
84895561196
-
CaMKIIdelta subtypes: localization and function
-
Gray C.B., Heller Brown J. CaMKIIdelta subtypes: localization and function. Front Pharmacol 2014, 5:15.
-
(2014)
Front Pharmacol
, vol.5
, pp. 15
-
-
Gray, C.B.1
Heller, B.J.2
-
34
-
-
0033781028
-
Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
-
Dzhura I., Wu Y., Colbran R.J., Balser J.R., Anderson M.E. Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol 2000, 2:173-177.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 173-177
-
-
Dzhura, I.1
Wu, Y.2
Colbran, R.J.3
Balser, J.R.4
Anderson, M.E.5
-
35
-
-
0037059791
-
2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity
-
2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem 2002, 277:1261-1267.
-
(2002)
J Biol Chem
, vol.277
, pp. 1261-1267
-
-
Zhang, T.1
Johnson, E.N.2
Gu, Y.3
Morissette, M.R.4
Sah, V.P.5
Gigena, M.S.6
-
36
-
-
0038643573
-
The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure
-
Zhang T., Maier L.S., Dalton N.D., Miyamoto S., Ross J., Bers D.M., et al. The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ Res 2003, 92:912-919.
-
(2003)
Circ Res
, vol.92
, pp. 912-919
-
-
Zhang, T.1
Maier, L.S.2
Dalton, N.D.3
Miyamoto, S.4
Ross, J.5
Bers, D.M.6
-
38
-
-
84856087553
-
Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes
-
Mishra S., Gray C.B., Miyamoto S., Bers D.M., Brown J.H. Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes. Circ Res 2011, 109:1354-1362.
-
(2011)
Circ Res
, vol.109
, pp. 1354-1362
-
-
Mishra, S.1
Gray, C.B.2
Miyamoto, S.3
Bers, D.M.4
Brown, J.H.5
-
39
-
-
24344470264
-
The M-band: an elastic web that crosslinks thick filaments in the center of the sarcomere
-
Agarkova I., Perriard J.C. The M-band: an elastic web that crosslinks thick filaments in the center of the sarcomere. Trends Cell Biol 2005, 15:477-485.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 477-485
-
-
Agarkova, I.1
Perriard, J.C.2
-
40
-
-
0031034775
-
Molecular structure of the sarcomeric M band: mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin
-
Obermann W.M., Gautel M., Weber K., Furst D.O. Molecular structure of the sarcomeric M band: mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin. EMBO J 1997, 16:211-220.
-
(1997)
EMBO J
, vol.16
, pp. 211-220
-
-
Obermann, W.M.1
Gautel, M.2
Weber, K.3
Furst, D.O.4
-
41
-
-
0034616196
-
A novel marker for vertebrate embryonic heart, the EH-myomesin isoform
-
Agarkova I. A novel marker for vertebrate embryonic heart, the EH-myomesin isoform. J Biol Chem 2000, 275:10256-10264.
-
(2000)
J Biol Chem
, vol.275
, pp. 10256-10264
-
-
Agarkova, I.1
-
42
-
-
38349085336
-
Myomesin 3, a novel structural component of the M-band in striated muscle
-
Schoenauer R., Lange S., Hirschy A., Ehler E., Perriard J.C., Agarkova I. Myomesin 3, a novel structural component of the M-band in striated muscle. J Mol Biol 2008, 376:338-351.
-
(2008)
J Mol Biol
, vol.376
, pp. 338-351
-
-
Schoenauer, R.1
Lange, S.2
Hirschy, A.3
Ehler, E.4
Perriard, J.C.5
Agarkova, I.6
-
43
-
-
18844381078
-
Myomesin is a molecular spring with adaptable elasticity
-
Schoenauer R., Bertoncini P., Machaidze G., Aebi U., Perriard J.C., Hegner M., et al. Myomesin is a molecular spring with adaptable elasticity. J Mol Biol 2005, 349:367-379.
-
(2005)
J Mol Biol
, vol.349
, pp. 367-379
-
-
Schoenauer, R.1
Bertoncini, P.2
Machaidze, G.3
Aebi, U.4
Perriard, J.C.5
Hegner, M.6
-
44
-
-
0038069065
-
Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart
-
Siedner S., Kruger M., Schroeter M., Metzler D., Roell W., Fleischmann B.K., et al. Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart. J Phys 2003, 548:493-505.
-
(2003)
J Phys
, vol.548
, pp. 493-505
-
-
Siedner, S.1
Kruger, M.2
Schroeter, M.3
Metzler, D.4
Roell, W.5
Fleischmann, B.K.6
-
45
-
-
0142249475
-
M-band: a safeguard for sarcomere stability?
-
Agarkova I., Ehler E., Lange S., Schoenauer R., Perriard J.C. M-band: a safeguard for sarcomere stability?. J Muscle Res Cell Motil 2003, 24:191-203.
-
(2003)
J Muscle Res Cell Motil
, vol.24
, pp. 191-203
-
-
Agarkova, I.1
Ehler, E.2
Lange, S.3
Schoenauer, R.4
Perriard, J.C.5
-
46
-
-
79957866415
-
EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy
-
Schoenauer R., Emmert M.Y., Felley A., Ehler E., Brokopp C., Weber B., et al. EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy. Basic Res Cardiol 2011, 106:233-247.
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 233-247
-
-
Schoenauer, R.1
Emmert, M.Y.2
Felley, A.3
Ehler, E.4
Brokopp, C.5
Weber, B.6
-
47
-
-
0034059761
-
Regulation of contraction in striated muscle
-
Gordon A.M., Homsher E., Regnier M. Regulation of contraction in striated muscle. Physiol Rev 2000, 80:853-924.
-
(2000)
Physiol Rev
, vol.80
, pp. 853-924
-
-
Gordon, A.M.1
Homsher, E.2
Regnier, M.3
-
48
-
-
0025934457
-
Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle
-
Anderson P.A., Malouf N.N., Oakeley A.E., Pagani E.D., Allen P.D. Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle. Circ Res 1991, 69:1226-1233.
-
(1991)
Circ Res
, vol.69
, pp. 1226-1233
-
-
Anderson, P.A.1
Malouf, N.N.2
Oakeley, A.E.3
Pagani, E.D.4
Allen, P.D.5
-
49
-
-
0028792519
-
Molecular cloning of human cardiac troponin T isoforms: expression in developing and failing heart
-
Townsend P.J., Barton P.J., Yacoub M.H., Farza H. Molecular cloning of human cardiac troponin T isoforms: expression in developing and failing heart. J Mol Cell Cardiol 1995, 27:2223-2236.
-
(1995)
J Mol Cell Cardiol
, vol.27
, pp. 2223-2236
-
-
Townsend, P.J.1
Barton, P.J.2
Yacoub, M.H.3
Farza, H.4
-
50
-
-
0037144508
-
Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart
-
Gomes A.V., Guzman G., Zhao J., Potter J.D. Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart. J Biol Chem 2002, 277:35341-35349.
-
(2002)
J Biol Chem
, vol.277
, pp. 35341-35349
-
-
Gomes, A.V.1
Guzman, G.2
Zhao, J.3
Potter, J.D.4
-
51
-
-
0028943382
-
Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart
-
Anderson P.A., Greig A., Mark T.M., Malouf N.N., Oakeley A.E., Ungerleider R.M., et al. Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart. Circ Res 1995, 76:681-686.
-
(1995)
Circ Res
, vol.76
, pp. 681-686
-
-
Anderson, P.A.1
Greig, A.2
Mark, T.M.3
Malouf, N.N.4
Oakeley, A.E.5
Ungerleider, R.M.6
-
52
-
-
77951622995
-
2+-sensitivity and arrhythmia susceptibility
-
2+-sensitivity and arrhythmia susceptibility. J Mol Cell Cardiol 2010, 48:824-833.
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 824-833
-
-
Huke, S.1
Knollmann, B.C.2
-
53
-
-
20444443019
-
Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development
-
Ladd A.N., Stenberg M.G., Swanson M.S., Cooper T.A. Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development. Dev Dyn 2005, 233:783-793.
-
(2005)
Dev Dyn
, vol.233
, pp. 783-793
-
-
Ladd, A.N.1
Stenberg, M.G.2
Swanson, M.S.3
Cooper, T.A.4
-
54
-
-
0036203307
-
Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing
-
Charlet B.N., Logan P., Singh G., Cooper T.A. Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Mol Cell 2002, 9:649-658.
-
(2002)
Mol Cell
, vol.9
, pp. 649-658
-
-
Charlet, B.N.1
Logan, P.2
Singh, G.3
Cooper, T.A.4
-
55
-
-
4143120231
-
Muscleblind proteins regulate alternative splicing
-
Ho T.H., Charlet B.N., Poulos M.G., Singh G., Swanson M.S., Cooper T.A. Muscleblind proteins regulate alternative splicing. EMBO J 2004, 23:3103-3112.
-
(2004)
EMBO J
, vol.23
, pp. 3103-3112
-
-
Ho, T.H.1
Charlet, B.N.2
Poulos, M.G.3
Singh, G.4
Swanson, M.S.5
Cooper, T.A.6
-
56
-
-
77953762074
-
Coexistence of cardiac troponin T variants reduces heart efficiency
-
Feng H.Z., Jin J.P. Coexistence of cardiac troponin T variants reduces heart efficiency. Am J Physiol Heart Circ Physiol 2010, 299:H97-H105.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
, pp. H97-H105
-
-
Feng, H.Z.1
Jin, J.P.2
-
57
-
-
78651248717
-
Troponin T isoforms and posttranscriptional modifications: evolution, regulation and function
-
Wei B., Jin J.P. Troponin T isoforms and posttranscriptional modifications: evolution, regulation and function. Arch Biochem Biophys 2011, 505:144-154.
-
(2011)
Arch Biochem Biophys
, vol.505
, pp. 144-154
-
-
Wei, B.1
Jin, J.P.2
-
58
-
-
3142772675
-
Expression of a novel cardiac-specific tropomyosin isoform in humans
-
Denz C.R., Narshi A., Zajdel R.W., Dube D.K. Expression of a novel cardiac-specific tropomyosin isoform in humans. Biochem Biophys Res Commun 2004, 320:1291-1297.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 1291-1297
-
-
Denz, C.R.1
Narshi, A.2
Zajdel, R.W.3
Dube, D.K.4
-
59
-
-
76649084202
-
Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform
-
Rajan S., Jagatheesan G., Karam C.N., Alves M.L., Bodi I., Schwartz A., et al. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation 2010, 121:410-418.
-
(2010)
Circulation
, vol.121
, pp. 410-418
-
-
Rajan, S.1
Jagatheesan, G.2
Karam, C.N.3
Alves, M.L.4
Bodi, I.5
Schwartz, A.6
-
60
-
-
0037470052
-
Characterization and in vivo functional analysis of splice variants of cypher
-
Huang C., Zhou Q., Liang P., Hollander M.S., Sheikh F., Li X., et al. Characterization and in vivo functional analysis of splice variants of cypher. J Biol Chem 2003, 278:7360-7365.
-
(2003)
J Biol Chem
, vol.278
, pp. 7360-7365
-
-
Huang, C.1
Zhou, Q.2
Liang, P.3
Hollander, M.S.4
Sheikh, F.5
Li, X.6
-
61
-
-
84924110084
-
Ablation of cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy
-
Zhou Q., Chu P.H., Huang C., Cheng C.F., Martone M.E., Knoll G., et al. Ablation of cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy. J Cell Biol 2001, 155:605-612.
-
(2001)
J Cell Biol
, vol.155
, pp. 605-612
-
-
Zhou, Q.1
Chu, P.H.2
Huang, C.3
Cheng, C.F.4
Martone, M.E.5
Knoll, G.6
-
62
-
-
79954480914
-
Selective deletion of long but not short cypher isoforms leads to late-onset dilated cardiomyopathy
-
Cheng H., Zheng M., Peter A.K., Kimura K., Li X., Ouyang K., et al. Selective deletion of long but not short cypher isoforms leads to late-onset dilated cardiomyopathy. Hum Mol Genet 2011, 20:1751-1762.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1751-1762
-
-
Cheng, H.1
Zheng, M.2
Peter, A.K.3
Kimura, K.4
Li, X.5
Ouyang, K.6
-
63
-
-
58949087565
-
Cardiac-specific ablation of cypher leads to a severe form of dilated cardiomyopathy with premature death
-
Zheng M., Cheng H., Li X., Zhang J., Cui L., Ouyang K., et al. Cardiac-specific ablation of cypher leads to a severe form of dilated cardiomyopathy with premature death. Hum Mol Genet 2009, 18:701-713.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 701-713
-
-
Zheng, M.1
Cheng, H.2
Li, X.3
Zhang, J.4
Cui, L.5
Ouyang, K.6
-
64
-
-
0033538565
-
Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C
-
Zhou Q., Ruiz-Lozano P., Martone M.E., Chen J. Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C. J Biol Chem 1999, 274:19807-19813.
-
(1999)
J Biol Chem
, vol.274
, pp. 19807-19813
-
-
Zhou, Q.1
Ruiz-Lozano, P.2
Martone, M.E.3
Chen, J.4
-
65
-
-
67649410687
-
Impaired binding of ZASP/cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy
-
Arimura T., Inagaki N., Hayashi T., Shichi D., Sato A., Hinohara K., et al. Impaired binding of ZASP/cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy. Cardiovasc Res 2009, 83:80-88.
-
(2009)
Cardiovasc Res
, vol.83
, pp. 80-88
-
-
Arimura, T.1
Inagaki, N.2
Hayashi, T.3
Shichi, D.4
Sato, A.5
Hinohara, K.6
-
66
-
-
84861398174
-
RNA-binding protein RBM24 is required for sarcomere assembly and heart contractility
-
Poon K.L., Tan K.T., Wei Y.Y., Ng C.P., Colman A., Korzh V., et al. RNA-binding protein RBM24 is required for sarcomere assembly and heart contractility. Cardiovasc Res 2012, 94:418-427.
-
(2012)
Cardiovasc Res
, vol.94
, pp. 418-427
-
-
Poon, K.L.1
Tan, K.T.2
Wei, Y.Y.3
Ng, C.P.4
Colman, A.5
Korzh, V.6
-
67
-
-
78650526355
-
SkNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration
-
Park C.Y., Pierce S.A., von Drehle M., Ivey K.N., Morgan J.A., Blau H.M., et al. skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. Proc Natl Acad Sci U S A 2010, 107:20750-20755.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 20750-20755
-
-
Park, C.Y.1
Pierce, S.A.2
von Drehle, M.3
Ivey, K.N.4
Morgan, J.A.5
Blau, H.M.6
-
68
-
-
3242659054
-
Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo
-
Mientjes E.J., Willemsen R., Kirkpatrick L.L., Nieuwenhuizen I.M., Hoogeveen-Westerveld M., Verweij M., et al. Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet 2004, 13:1291-1302.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1291-1302
-
-
Mientjes, E.J.1
Willemsen, R.2
Kirkpatrick, L.L.3
Nieuwenhuizen, I.M.4
Hoogeveen-Westerveld, M.5
Verweij, M.6
-
69
-
-
79961032285
-
Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle
-
Whitman S.A., Cover C., Yu L., Nelson D.L., Zarnescu D.C., Gregorio C.C. Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circ Res 2011, 109:262-271.
-
(2011)
Circ Res
, vol.109
, pp. 262-271
-
-
Whitman, S.A.1
Cover, C.2
Yu, L.3
Nelson, D.L.4
Zarnescu, D.C.5
Gregorio, C.C.6
-
70
-
-
84862128171
-
Cantu syndrome is caused by mutations in ABCC9
-
van Bon B.W., Gilissen C., Grange D.K., Hennekam R.C., Kayserili H., Engels H., et al. Cantu syndrome is caused by mutations in ABCC9. Am J Hum Genet 2012, 90:1094-1101.
-
(2012)
Am J Hum Genet
, vol.90
, pp. 1094-1101
-
-
van Bon, B.W.1
Gilissen, C.2
Grange, D.K.3
Hennekam, R.C.4
Kayserili, H.5
Engels, H.6
-
71
-
-
33645080673
-
The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins
-
Bosch-Comas A., Lindsten K., Gonzalez-Duarte R., Masucci M.G., Marfany G. The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins. Cell Mol Life Sci 2006, 63:723-734.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 723-734
-
-
Bosch-Comas, A.1
Lindsten, K.2
Gonzalez-Duarte, R.3
Masucci, M.G.4
Marfany, G.5
-
72
-
-
0035231979
-
Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25
-
RESEARCH0043.
-
Valero R., Bayes M., Francisca Sanchez-Font M., Gonzalez-Angulo O., Gonzalez-Duarte R., Marfany G. Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25. Genome Biol 2001, 2. RESEARCH0043.
-
(2001)
Genome Biol
, vol.2
-
-
Valero, R.1
Bayes, M.2
Francisca Sanchez-Font, M.3
Gonzalez-Angulo, O.4
Gonzalez-Duarte, R.5
Marfany, G.6
-
73
-
-
84893698618
-
Rbm24, an RNA-binding protein and a target of p53, regulates p21 expression via mRNA stability
-
Jiang Y., Zhang M., Qian Y., Xu E., Zhang J., Chen X. Rbm24, an RNA-binding protein and a target of p53, regulates p21 expression via mRNA stability. J Biol Chem 2014, 289:3164-3175.
-
(2014)
J Biol Chem
, vol.289
, pp. 3164-3175
-
-
Jiang, Y.1
Zhang, M.2
Qian, Y.3
Xu, E.4
Zhang, J.5
Chen, X.6
-
74
-
-
84855916545
-
Protein-RNA interactions: new genomic technologies and perspectives
-
Konig J., Zarnack K., Luscombe N.M., Ule J. Protein-RNA interactions: new genomic technologies and perspectives. Nat Rev Gen 2011, 13:77-83.
-
(2011)
Nat Rev Gen
, vol.13
, pp. 77-83
-
-
Konig, J.1
Zarnack, K.2
Luscombe, N.M.3
Ule, J.4
-
75
-
-
84861969926
-
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
-
Castello A., Fischer B., Eichelbaum K., Horos R., Beckmann B.M., Strein C., et al. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 2012, 149:1393-1406.
-
(2012)
Cell
, vol.149
, pp. 1393-1406
-
-
Castello, A.1
Fischer, B.2
Eichelbaum, K.3
Horos, R.4
Beckmann, B.M.5
Strein, C.6
-
76
-
-
79955158683
-
Systemic administration of PRO051 in Duchenne's muscular dystrophy
-
Goemans N.M., Tulinius M., van den Akker J.T., Burm B.E., Ekhart P.F., Heuvelmans N., et al. Systemic administration of PRO051 in Duchenne's muscular dystrophy. N Engl J Med 2011, 364:1513-1522.
-
(2011)
N Engl J Med
, vol.364
, pp. 1513-1522
-
-
Goemans, N.M.1
Tulinius, M.2
van den Akker, J.T.3
Burm, B.E.4
Ekhart, P.F.5
Heuvelmans, N.6
-
77
-
-
17644373758
-
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
-
Scaffidi P., Misteli T. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med 2005, 11:440-445.
-
(2005)
Nat Med
, vol.11
, pp. 440-445
-
-
Scaffidi, P.1
Misteli, T.2
-
78
-
-
80053902729
-
Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
-
Hua Y., Sahashi K., Rigo F., Hung G., Horev G., Bennett C.F., et al. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model. Nature 2011, 478:123-126.
-
(2011)
Nature
, vol.478
, pp. 123-126
-
-
Hua, Y.1
Sahashi, K.2
Rigo, F.3
Hung, G.4
Horev, G.5
Bennett, C.F.6
-
79
-
-
84864439453
-
Targeting nuclear RNA for in vivo correction of myotonic dystrophy
-
Wheeler T.M., Leger A.J., Pandey S.K., MacLeod A.R., Nakamori M., Cheng S.H., et al. Targeting nuclear RNA for in vivo correction of myotonic dystrophy. Nature 2012, 488:111-115.
-
(2012)
Nature
, vol.488
, pp. 111-115
-
-
Wheeler, T.M.1
Leger, A.J.2
Pandey, S.K.3
MacLeod, A.R.4
Nakamori, M.5
Cheng, S.H.6
-
80
-
-
79959527987
-
Calcineurin splicing variant calcineurin Abeta1 improves cardiac function after myocardial infarction without inducing hypertrophy
-
Felkin L.E., Narita T., Germack R., Shintani Y., Takahashi K., Sarathchandra P., et al. Calcineurin splicing variant calcineurin Abeta1 improves cardiac function after myocardial infarction without inducing hypertrophy. Circulation 2011, 123:2838-2847.
-
(2011)
Circulation
, vol.123
, pp. 2838-2847
-
-
Felkin, L.E.1
Narita, T.2
Germack, R.3
Shintani, Y.4
Takahashi, K.5
Sarathchandra, P.6
-
81
-
-
79959733942
-
IGF-1Ea induces vessel formation after injury and mediates bone marrow and heart cross-talk through the expression of specific cytokines
-
Santini M.P., Lexow J., Borsellino G., Slonimski E., Zarrinpashneh E., Poggioli T., et al. IGF-1Ea induces vessel formation after injury and mediates bone marrow and heart cross-talk through the expression of specific cytokines. Biochem Biophys Res Commun 2011, 410:201-207.
-
(2011)
Biochem Biophys Res Commun
, vol.410
, pp. 201-207
-
-
Santini, M.P.1
Lexow, J.2
Borsellino, G.3
Slonimski, E.4
Zarrinpashneh, E.5
Poggioli, T.6
|