Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing

Molecular Cell

Volumn 9, Issue 3, 2002, Pages 649-658

  Charlet B, Nicolas ^a   Logan, Penny ^a   Singh, Gopal ^a   Cooper, Thomas A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYPYRIMIDINE TRACT BINDING PROTEIN; PROTEIN; PROTEIN ETR 3; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BINDING SITE; CELL TYPE; CONTROLLED STUDY; CROSS LINKING; EMBRYO; EXON; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MUSCLE CELL; MUTANT; NONHUMAN; PROTEIN BINDING; PROTEIN MOTIF; SKELETAL MUSCLE;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0036203307     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00479-3     Document Type: Article

References (36)

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7. A single cardiac troponin T gene generates embryonic and adult isoforms via developmentally regulated alternate splicing
8. Selection of splice sites in pre-mRNAs with short internal exons
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15. Initial sequencing and analysis of the human genome
16. A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing
17. Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain
18. Regulation of alternative 3′ splice site selection by constitutive splicing factors
19. Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
20. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer
21. Mutation of PTB binding sites causes misregulation of alternative 3′ splice site selection in vivo
22. Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein
23. A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing
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25. Muscle-specific splicing enhancers regulate inclusion of the cardiac troponin T alternative exon in embryonic skeletal muscle
26. Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy
27. A yeast intronic splicing enhancer and Nam8p are required for Mer1p-activated splicing
28. The CUG-binding protein binds specifically to U/G dinucleotide repeats in a yeast three-hybrid system
29. Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy
30. CUG repeat binding protein (CUGBP1) interacts with the 5′ region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoforms
31. Post-transcriptional regulation: The dawn of PTB
32. Polypyrimidine tract binding protein antagonizes exon definition
33. SC35 plays a role in T cell development and alternative splicing of CD45
34. Translational repressor bruno plays multiple roles in development and is widely conserved
35. The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element
36. Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB