메뉴 건너뛰기




Volumn 289, Issue 6, 2014, Pages 3164-3175

Rbm24, an RNA-binding Protein and a Target of p53, Regulates p21 Expression via mRNA Stability

Author keywords

[No Author keywords available]

Indexed keywords

CANCER BIOLOGY; CELL CYCLE; MRNA DECAY; P53; RNA-BINDING PROTEIN;

EID: 84893698618     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.524413     Document Type: Article
Times cited : (59)

References (42)
  • 1
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • Vogelstein, B., Lane, D., and Levine, A. J. (2000) Surfing the p53 network. Nature 408, 307-310
    • (2000) Nature , vol.408 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 4
    • 41449091585 scopus 로고    scopus 로고
    • Dec1, a basic helix-loophelix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence
    • Qian, Y., Zhang, J., Yan, B., and Chen, X. (2008) DEC1, a basic helix-loophelix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence. J. Biol. Chem. 283, 2896-2905
    • (2008) J. Biol. Chem. , vol.283 , pp. 2896-2905
    • Qian, Y.1    Zhang, J.2    Yan, B.3    Chen, X.4
  • 6
    • 0029125496 scopus 로고
    • Identification of two khdomain proteins in the-globinmrnpstability complex
    • Kiledjian, M., Wang, X., and Liebhaber, S. A. (1995) Identification of two KHdomain proteins in the-globinmRNPstability complex.EMBOJ. 14, 4357-4364
    • (1995) EMBOJ. , vol.14 , pp. 4357-4364
    • Kiledjian, M.1    Wang, X.2    Liebhaber, S.A.3
  • 8
    • 0033153348 scopus 로고    scopus 로고
    • Hnrnp complexes: Composition, structure, and function
    • Krecic, A. M., and Swanson, M. S. (1999) hnRNP complexes: composition, structure, and function. Curr. Opin. Cell Biol. 11, 363-371
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 363-371
    • Krecic, A.M.1    Swanson, M.S.2
  • 9
    • 84862300106 scopus 로고    scopus 로고
    • Versatility of rna-binding proteins in cancer
    • Wurth, L. (2012) Versatility of RNA-binding proteins in cancer. Comp. Funct. Genomics 2012, 178525
    • (2012) Comp. Funct. Genomics , vol.2012 , pp. 178525
    • Wurth, L.1
  • 11
    • 84859928841 scopus 로고    scopus 로고
    • Radiation sensitivity of esophageal adenocarcinoma: The contribution of the rna-binding protein rnpc1 and p21-mediated cell cycle arrest to radioresistance
    • Hötte, G. J., Linam-Lennon, N., Reynolds, J. V., and Maher, S. G. (2012) Radiation sensitivity of esophageal adenocarcinoma: the contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance. Radiat. Res. 177, 272-279
    • (2012) Radiat. Res. , vol.177 , pp. 272-279
    • Hötte, G.J.1    Linam-Lennon, N.2    Reynolds, J.V.3    Maher, S.G.4
  • 13
    • 33751100684 scopus 로고    scopus 로고
    • Rnpc1, an rna-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript
    • Shu, L., Yan, W., and Chen, X. (2006) RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript. Genes Dev. 20, 2961-2972
    • (2006) Genes Dev. , vol.20 , pp. 2961-2972
    • Shu, L.1    Yan, W.2    Chen, X.3
  • 14
    • 77952312858 scopus 로고    scopus 로고
    • Rnpc1 modulates the rnabinding activity of, and cooperates with, hur to regulate p21 mrna stability
    • Cho, S. J., Zhang, J., and Chen, X. (2010) RNPC1 modulates the RNAbinding activity of, and cooperates with, HuR to regulate p21 mRNA stability. Nucleic Acids Res. 38, 2256-2267
    • (2010) Nucleic Acids Res. , vol.38 , pp. 2256-2267
    • Cho, S.J.1    Zhang, J.2    Chen, X.3
  • 15
    • 70450194858 scopus 로고    scopus 로고
    • Rna-binding proteins rbm38 and rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways
    • Miyamoto, S., Hidaka, K., Jin, D., and Morisaki, T. (2009) RNA-binding proteins Rbm38 and Rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways. Genes Cells 14, 1241-1252
    • (2009) Genes Cells , vol.14 , pp. 1241-1252
    • Miyamoto, S.1    Hidaka, K.2    Jin, D.3    Morisaki, T.4
  • 17
    • 84861398174 scopus 로고    scopus 로고
    • Rna-binding protein rbm24 is required for sarcomere assembly and heart contractility
    • Poon, K. L., Tan, K. T., Wei, Y. Y., Ng, C. P., Colman, A., Korzh, V., and Xu, X. Q. (2012) RNA-binding protein RBM24 is required for sarcomere assembly and heart contractility. Cardiovasc. Res. 94, 418-427
    • (2012) Cardiovasc. Res. , vol.94 , pp. 418-427
    • Poon, K.L.1    Tan, K.T.2    Wei, Y.Y.3    Ng, C.P.4    Colman, A.5    Korzh, V.6    Xu, X.Q.7
  • 18
    • 0032483461 scopus 로고
    • Ectopic p21waf1 expression induces differentiation-specific cell cycle changes in pc12 cells characteristic of nerve growth factor treatment
    • Erhardt, J. A., and Pittman, R. N. (1998) Ectopic p21WAF1 expression induces differentiation-specific cell cycle changes in PC12 cells characteristic of nerve growth factor treatment. J. Biol. Chem. 273, 23517-23523
    • (1988) J. Biol. Chem. , vol.273 , pp. 23517-23523
    • Erhardt, J.A.1    Pittman, R.N.2
  • 19
    • 0027332123 scopus 로고
    • Altered regulation of g1 cyclins in senescent human diploid fibroblasts: Accumulation of inactive cyclin e-cdk2 and cyclin d1-cdk2 complexes
    • Dulić, V., Drullinger, L. F., Lees, E., Reed, S. I., and Stein, G. H. (1993) Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc. Natl. Acad. Sci. U.S.A. 90, 11034-11038
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 11034-11038
    • Dulić, V.1    Drullinger, L.F.2    Lees, E.3    Reed, S.I.4    Stein, G.H.5
  • 20
    • 0033594245 scopus 로고    scopus 로고
    • Induced p21waf expression in h1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin
    • Wang, Y., Blandino, G., and Givol, D. (1999) Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin. Oncogene 18, 2643-2649
    • (1999) Oncogene , vol.18 , pp. 2643-2649
    • Wang, Y.1    Blandino, G.2    Givol, D.3
  • 21
    • 77951985216 scopus 로고    scopus 로고
    • Examination of the expanding pathways for the regulation of p21 expression and activity
    • Jung, Y. S., Qian, Y., and Chen, X. (2010) Examination of the expanding pathways for the regulation of p21 expression and activity. Cell. Signal. 22, 1003-1012
    • (2010) Cell. Signal. , vol.22 , pp. 1003-1012
    • Jung, Y.S.1    Qian, Y.2    Chen, X.3
  • 23
    • 0032161624 scopus 로고    scopus 로고
    • P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang, A., Kaghad, M., Wang, Y., Gillett, E., Fleming, M. D., Dötsch, V., Andrews, N. C., Caput, D., and McKeon, F. (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol. Cell 2, 305-316
    • (1998) Mol. Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dötsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9
  • 24
    • 0032533514 scopus 로고    scopus 로고
    • The potential tumor suppressor p73 differentially regulates cellular p53 target genes
    • Zhu, J., Jiang, J., Zhou, W., and Chen, X. (1998) The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res. 58, 5061-5065
    • (1998) Cancer Res. , vol.58 , pp. 5061-5065
    • Zhu, J.1    Jiang, J.2    Zhou, W.3    Chen, X.4
  • 25
    • 0032493757 scopus 로고    scopus 로고
    • P21waf1 mrna contains a conserved element in its 3-untranslated region that is bound by the elav like mrna-stabilizing proteins
    • Joseph, B., Orlian, M., and Furneaux, H. (1998) p21waf1 mRNA contains a conserved element in its 3-untranslated region that is bound by the Elav like mRNA-stabilizing proteins. J. Biol. Chem. 273, 20511-20516
    • (1998) J. Biol. Chem. , vol.273 , pp. 20511-20516
    • Joseph, B.1    Orlian, M.2    Furneaux, H.3
  • 27
    • 10344256186 scopus 로고    scopus 로고
    • Prostaglandin a2-mediated stabilization of p21 mrna through an erk-dependent pathway requiring the rna-binding protein hur
    • Yang, X., Wang, W., Fan, J., Lal, A., Yang, D., Cheng, H., and Gorospe, M. (2004) Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR. J. Biol. Chem. 279, 49298-49306
    • (2004) J. Biol. Chem. , vol.279 , pp. 49298-49306
    • Yang, X.1    Wang, W.2    Fan, J.3    Lal, A.4    Yang, D.5    Cheng, H.6    Gorospe, M.7
  • 28
    • 78651321770 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor p21 is regulated by rna-binding protein pcbp4 via mrna stability
    • Scoumanne, A., Cho, S. J., Zhang, J., and Chen, X. (2011) The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability. Nucleic Acids Res. 39, 213-224
    • (2011) Nucleic Acids Res. , vol.39 , pp. 213-224
    • Scoumanne, A.1    Cho, S.J.2    Zhang, J.3    Chen, X.4
  • 29
    • 66149143922 scopus 로고    scopus 로고
    • Depletion of the poly(c)-binding proteins-cp1 and-cp2 from k562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (cdkn1a) and g1 arrest
    • Waggoner, S. A., Johannes, G. J., and Liebhaber, S. A. (2009) Depletion of the poly(C)-binding proteins-CP1 and-CP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest. J. Biol. Chem. 284, 9039-9049
    • (2009) J. Biol. Chem. , vol.284 , pp. 9039-9049
    • Waggoner, S.A.1    Johannes, G.J.2    Liebhaber, S.A.3
  • 30
    • 0028048773 scopus 로고
    • Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor
    • Johansen, F. E., and Prywes, R. (1994) Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol. Cell. Biol. 14, 5920-5928
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5920-5928
    • Johansen, F.E.1    Prywes, R.2
  • 31
    • 84867240307 scopus 로고    scopus 로고
    • Serine 123 phosphorylation modulates p21 protein stability and activity by suppressing ubiquitin-independent proteasomal degradation
    • Chen, X., Zhang, J., Zhang, M., Liu, S., Yan, W., and Jung, J. (2012) Serine 123 phosphorylation modulates p21 protein stability and activity by suppressing ubiquitin-independent proteasomal degradation. J. Biol. Chem. 287, 34410-34418
    • (2012) J. Biol. Chem. , vol.287 , pp. 34410-34418
    • Chen, X.1    Zhang, J.2    Zhang, M.3    Liu, S.4    Yan, W.5    Jung, J.6
  • 32
    • 0029033333 scopus 로고
    • P53, through p21waf1/cip1, induces cyclin d1 synthesis
    • Chen, X., Bargonetti, J., and Prives, C. (1995) p53, through p21WAF1/CIP1, induces cyclin D1 synthesis. Cancer Res. 55, 4257-4263
    • (1995) Cancer Res. , vol.55 , pp. 4257-4263
    • Chen, X.1    Bargonetti, J.2    Prives, C.3
  • 34
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of s phase and mitosis induced by anticancer agents in cells lacking p21
    • Waldman, T., Lengauer, C., Kinzler, K. W., and Vogelstein, B. (1996) Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713-716
    • (1996) Nature , vol.381 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 35
    • 32044449228 scopus 로고    scopus 로고
    • Dna polymerase-, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates thedna damage checkpoint and p53 activation
    • Liu, G., and Chen, X. (2006) DNA polymerase-, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates theDNA damage checkpoint and p53 activation. Mol. Cell. Biol. 26, 1398-1413
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 1398-1413
    • Liu, G.1    Chen, X.2
  • 36
    • 33744940368 scopus 로고    scopus 로고
    • Tumor suppressor gene-inducible cell lines
    • Dohn, M., Nozell, S., Willis, A., and Chen, X. (2003) Tumor suppressor gene-inducible cell lines. Methods Mol. Biol. 223, 221-235
    • (2003) Methods Mol. Biol. , vol.223 , pp. 221-235
    • Dohn, M.1    Nozell, S.2    Willis, A.3    Chen, X.4
  • 37
    • 84876927156 scopus 로고    scopus 로고
    • Mdm2 expression is repressed by the rna-binding protein rnpc1 via mrna stability
    • Xu, E., Zhang, J., and Chen, X. (2013) MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability. Oncogene 32, 2169-2178
    • (2013) Oncogene , vol.32 , pp. 2169-2178
    • Xu, E.1    Zhang, J.2    Chen, X.3
  • 39
    • 59249094289 scopus 로고    scopus 로고
    • Posttranscriptional regulation of p53 and its targets by rna-binding proteins
    • Zhang, J., and Chen, X. (2008) Posttranscriptional regulation of p53 and its targets by RNA-binding proteins. Curr. Mol. Med. 8, 845-849
    • (2008) Curr. Mol. Med. , vol.8 , pp. 845-849
    • Zhang, J.1    Chen, X.2
  • 42
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein, B., and Kinzler, K. W. (2004) Cancer genes and the pathways they control. Nat. Med. 10, 789-799
    • (2004) Nat. Med. , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.