-
1
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein, B., Lane, D., and Levine, A. J. (2000) Surfing the p53 network. Nature 408, 307-310
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
2
-
-
0027359827
-
Waf1, a potential mediator of p53 tumor suppression
-
el-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.1
Tokino, T.2
Velculescu, V.3
Levy, D.4
Parsons, R.5
Trent, J.6
Lin, D.7
Mercer, W.8
Kinzler, K.9
Vogelstein, B.10
-
3
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
-
Jeffers, J. R., Parganas, E., Lee, Y., Yang, C., Wang, J., Brennan, J., MacLean, K. H., Han, J., Chittenden, T., Ihle, J. N., McKinnon, P. J., Cleveland, J. L., and Zambetti, G. P. (2003) Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell 4, 321-328
-
(2003)
Cancer Cell
, vol.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
Yang, C.4
Wang, J.5
Brennan, J.6
MacLean, K.H.7
Han, J.8
Chittenden, T.9
Ihle, J.N.10
McKinnon, P.J.11
Cleveland, J.L.12
Zambetti, G.P.13
-
4
-
-
41449091585
-
Dec1, a basic helix-loophelix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence
-
Qian, Y., Zhang, J., Yan, B., and Chen, X. (2008) DEC1, a basic helix-loophelix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence. J. Biol. Chem. 283, 2896-2905
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2896-2905
-
-
Qian, Y.1
Zhang, J.2
Yan, B.3
Chen, X.4
-
5
-
-
0028294605
-
Waf1/cip1 is induced in p53-mediated g1 arrest and apoptosis
-
el-Deiry, W. S., Harper, J. W., O'Connor, P. M., Velculescu, V. E., Canman, C. E., Jackman, J., Pietenpol, J. A., Burrell, M., Hill, D. E., and Wang, Y. (1994) WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 54, 1169-1174
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.1
Harper, J.2
O'Connor, P.3
Velculescu, V.4
Canman, C.5
Jackman, J.6
Pietenpol, J.7
Burrell, M.8
Hill, D.9
Wang, Y.10
-
6
-
-
0029125496
-
Identification of two khdomain proteins in the-globinmrnpstability complex
-
Kiledjian, M., Wang, X., and Liebhaber, S. A. (1995) Identification of two KHdomain proteins in the-globinmRNPstability complex.EMBOJ. 14, 4357-4364
-
(1995)
EMBOJ.
, vol.14
, pp. 4357-4364
-
-
Kiledjian, M.1
Wang, X.2
Liebhaber, S.A.3
-
7
-
-
0032575526
-
-
Collier, B., Goobar-Larsson, L., Sokolowski, M., and Schwartz, S. (1998) J. Biol. Chem. 273, 22648-22656
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22648-22656
-
-
Collier, B.1
Goobar-Larsson, L.2
Sokolowski, M.3
Schwartz, S.4
-
8
-
-
0033153348
-
Hnrnp complexes: Composition, structure, and function
-
Krecic, A. M., and Swanson, M. S. (1999) hnRNP complexes: composition, structure, and function. Curr. Opin. Cell Biol. 11, 363-371
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 363-371
-
-
Krecic, A.M.1
Swanson, M.S.2
-
9
-
-
84862300106
-
Versatility of rna-binding proteins in cancer
-
Wurth, L. (2012) Versatility of RNA-binding proteins in cancer. Comp. Funct. Genomics 2012, 178525
-
(2012)
Comp. Funct. Genomics
, vol.2012
, pp. 178525
-
-
Wurth, L.1
-
10
-
-
58249089865
-
Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression
-
Carvalho, B., Postma, C., Mongera, S., Hopmans, E., Diskin, S., van de Wiel, M. A., van Criekinge, W., Thas, O., Matthäi, A., Cuesta, M. A., Terhaar Sive Droste, J. S., Craanen, M., Schröck, E., Ylstra, B., and Meijer, G. A. (2009) Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression. Gut 58, 79-89
-
(2009)
Gut
, vol.58
, pp. 79-89
-
-
Carvalho, B.1
Postma, C.2
Mongera, S.3
Hopmans, E.4
Diskin, S.5
Van De Wiel, M.A.6
Van Criekinge, W.7
Thas, O.8
Matthäi, A.9
Cuesta, M.A.10
Terhaar Sive Droste, J.S.11
Craanen, M.12
Schröck, E.13
Ylstra, B.14
Meijer, G.A.15
-
11
-
-
84859928841
-
Radiation sensitivity of esophageal adenocarcinoma: The contribution of the rna-binding protein rnpc1 and p21-mediated cell cycle arrest to radioresistance
-
Hötte, G. J., Linam-Lennon, N., Reynolds, J. V., and Maher, S. G. (2012) Radiation sensitivity of esophageal adenocarcinoma: the contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance. Radiat. Res. 177, 272-279
-
(2012)
Radiat. Res.
, vol.177
, pp. 272-279
-
-
Hötte, G.J.1
Linam-Lennon, N.2
Reynolds, J.V.3
Maher, S.G.4
-
12
-
-
79960424486
-
Translational repression of p53 by rnpc1, a p53 target overexpressed in lymphomas
-
Zhang, J., Cho, S. J., Shu, L., Yan, W., Guerrero, T., Kent, M., Skorupski, K., Chen, H., and Chen, X. (2011) Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas. Genes Dev. 25, 1528-1543
-
(2011)
Genes Dev.
, vol.25
, pp. 1528-1543
-
-
Zhang, J.1
Cho, S.J.2
Shu, L.3
Yan, W.4
Guerrero, T.5
Kent, M.6
Skorupski, K.7
Chen, H.8
Chen, X.9
-
13
-
-
33751100684
-
Rnpc1, an rna-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript
-
Shu, L., Yan, W., and Chen, X. (2006) RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript. Genes Dev. 20, 2961-2972
-
(2006)
Genes Dev.
, vol.20
, pp. 2961-2972
-
-
Shu, L.1
Yan, W.2
Chen, X.3
-
14
-
-
77952312858
-
Rnpc1 modulates the rnabinding activity of, and cooperates with, hur to regulate p21 mrna stability
-
Cho, S. J., Zhang, J., and Chen, X. (2010) RNPC1 modulates the RNAbinding activity of, and cooperates with, HuR to regulate p21 mRNA stability. Nucleic Acids Res. 38, 2256-2267
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 2256-2267
-
-
Cho, S.J.1
Zhang, J.2
Chen, X.3
-
15
-
-
70450194858
-
Rna-binding proteins rbm38 and rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways
-
Miyamoto, S., Hidaka, K., Jin, D., and Morisaki, T. (2009) RNA-binding proteins Rbm38 and Rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways. Genes Cells 14, 1241-1252
-
(2009)
Genes Cells
, vol.14
, pp. 1241-1252
-
-
Miyamoto, S.1
Hidaka, K.2
Jin, D.3
Morisaki, T.4
-
16
-
-
80054103930
-
Identification ofrnabinding motif proteins essential for cardiovascular development
-
Maragh, S., Miller, R. A., Bessling, S. L., McGaughey, D. M., Wessels, M. W., de Graaf, B., Stone, E. A., Bertoli-Avella, A. M., Gearhart, J. D., Fisher, S., and McCallion, A. S. (2011) Identification ofRNAbinding motif proteins essential for cardiovascular development. BMC Dev. Biol. 11, 62
-
(2011)
BMC Dev. Biol.
, vol.11
, pp. 62
-
-
Maragh, S.1
Miller, R.A.2
Bessling, S.L.3
McGaughey, D.M.4
Wessels, M.W.5
De Graaf, B.6
Stone, E.A.7
Bertoli-Avella, A.M.8
Gearhart, J.D.9
Fisher, S.10
McCallion, A.S.11
-
17
-
-
84861398174
-
Rna-binding protein rbm24 is required for sarcomere assembly and heart contractility
-
Poon, K. L., Tan, K. T., Wei, Y. Y., Ng, C. P., Colman, A., Korzh, V., and Xu, X. Q. (2012) RNA-binding protein RBM24 is required for sarcomere assembly and heart contractility. Cardiovasc. Res. 94, 418-427
-
(2012)
Cardiovasc. Res.
, vol.94
, pp. 418-427
-
-
Poon, K.L.1
Tan, K.T.2
Wei, Y.Y.3
Ng, C.P.4
Colman, A.5
Korzh, V.6
Xu, X.Q.7
-
18
-
-
0032483461
-
Ectopic p21waf1 expression induces differentiation-specific cell cycle changes in pc12 cells characteristic of nerve growth factor treatment
-
Erhardt, J. A., and Pittman, R. N. (1998) Ectopic p21WAF1 expression induces differentiation-specific cell cycle changes in PC12 cells characteristic of nerve growth factor treatment. J. Biol. Chem. 273, 23517-23523
-
(1988)
J. Biol. Chem.
, vol.273
, pp. 23517-23523
-
-
Erhardt, J.A.1
Pittman, R.N.2
-
19
-
-
0027332123
-
Altered regulation of g1 cyclins in senescent human diploid fibroblasts: Accumulation of inactive cyclin e-cdk2 and cyclin d1-cdk2 complexes
-
Dulić, V., Drullinger, L. F., Lees, E., Reed, S. I., and Stein, G. H. (1993) Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc. Natl. Acad. Sci. U.S.A. 90, 11034-11038
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 11034-11038
-
-
Dulić, V.1
Drullinger, L.F.2
Lees, E.3
Reed, S.I.4
Stein, G.H.5
-
20
-
-
0033594245
-
Induced p21waf expression in h1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin
-
Wang, Y., Blandino, G., and Givol, D. (1999) Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin. Oncogene 18, 2643-2649
-
(1999)
Oncogene
, vol.18
, pp. 2643-2649
-
-
Wang, Y.1
Blandino, G.2
Givol, D.3
-
21
-
-
77951985216
-
Examination of the expanding pathways for the regulation of p21 expression and activity
-
Jung, Y. S., Qian, Y., and Chen, X. (2010) Examination of the expanding pathways for the regulation of p21 expression and activity. Cell. Signal. 22, 1003-1012
-
(2010)
Cell. Signal.
, vol.22
, pp. 1003-1012
-
-
Jung, Y.S.1
Qian, Y.2
Chen, X.3
-
22
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
Kaghad, M., Bonnet, H., Yang, A., Creancier, L., Biscan, J. C., Valent, A., Minty, A., Chalon, P., Lelias, J. M., Dumont, X., Ferrara, P., McKeon, F., and Caput, D. (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90, 809-819
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
Ferrara, P.11
McKeon, F.12
Caput, D.13
-
23
-
-
0032161624
-
P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
Yang, A., Kaghad, M., Wang, Y., Gillett, E., Fleming, M. D., Dötsch, V., Andrews, N. C., Caput, D., and McKeon, F. (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol. Cell 2, 305-316
-
(1998)
Mol. Cell
, vol.2
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dötsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
24
-
-
0032533514
-
The potential tumor suppressor p73 differentially regulates cellular p53 target genes
-
Zhu, J., Jiang, J., Zhou, W., and Chen, X. (1998) The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res. 58, 5061-5065
-
(1998)
Cancer Res.
, vol.58
, pp. 5061-5065
-
-
Zhu, J.1
Jiang, J.2
Zhou, W.3
Chen, X.4
-
25
-
-
0032493757
-
P21waf1 mrna contains a conserved element in its 3-untranslated region that is bound by the elav like mrna-stabilizing proteins
-
Joseph, B., Orlian, M., and Furneaux, H. (1998) p21waf1 mRNA contains a conserved element in its 3-untranslated region that is bound by the Elav like mRNA-stabilizing proteins. J. Biol. Chem. 273, 20511-20516
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20511-20516
-
-
Joseph, B.1
Orlian, M.2
Furneaux, H.3
-
26
-
-
0033959125
-
Hur regulates p21 mrna stabilization by uv light
-
Wang, W., Furneaux, H., Cheng, H., Caldwell, M. C., Hutter, D., Liu, Y., Holbrook, N., and Gorospe, M. (2000) HuR regulates p21 mRNA stabilization by UV light. Mol. Cell. Biol. 20, 760-769
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 760-769
-
-
Wang, W.1
Furneaux, H.2
Cheng, H.3
Caldwell, M.C.4
Hutter, D.5
Liu, Y.6
Holbrook, N.7
Gorospe, M.8
-
27
-
-
10344256186
-
Prostaglandin a2-mediated stabilization of p21 mrna through an erk-dependent pathway requiring the rna-binding protein hur
-
Yang, X., Wang, W., Fan, J., Lal, A., Yang, D., Cheng, H., and Gorospe, M. (2004) Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR. J. Biol. Chem. 279, 49298-49306
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49298-49306
-
-
Yang, X.1
Wang, W.2
Fan, J.3
Lal, A.4
Yang, D.5
Cheng, H.6
Gorospe, M.7
-
28
-
-
78651321770
-
The cyclin-dependent kinase inhibitor p21 is regulated by rna-binding protein pcbp4 via mrna stability
-
Scoumanne, A., Cho, S. J., Zhang, J., and Chen, X. (2011) The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability. Nucleic Acids Res. 39, 213-224
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 213-224
-
-
Scoumanne, A.1
Cho, S.J.2
Zhang, J.3
Chen, X.4
-
29
-
-
66149143922
-
Depletion of the poly(c)-binding proteins-cp1 and-cp2 from k562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (cdkn1a) and g1 arrest
-
Waggoner, S. A., Johannes, G. J., and Liebhaber, S. A. (2009) Depletion of the poly(C)-binding proteins-CP1 and-CP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest. J. Biol. Chem. 284, 9039-9049
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 9039-9049
-
-
Waggoner, S.A.1
Johannes, G.J.2
Liebhaber, S.A.3
-
30
-
-
0028048773
-
Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor
-
Johansen, F. E., and Prywes, R. (1994) Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol. Cell. Biol. 14, 5920-5928
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 5920-5928
-
-
Johansen, F.E.1
Prywes, R.2
-
31
-
-
84867240307
-
Serine 123 phosphorylation modulates p21 protein stability and activity by suppressing ubiquitin-independent proteasomal degradation
-
Chen, X., Zhang, J., Zhang, M., Liu, S., Yan, W., and Jung, J. (2012) Serine 123 phosphorylation modulates p21 protein stability and activity by suppressing ubiquitin-independent proteasomal degradation. J. Biol. Chem. 287, 34410-34418
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 34410-34418
-
-
Chen, X.1
Zhang, J.2
Zhang, M.3
Liu, S.4
Yan, W.5
Jung, J.6
-
32
-
-
0029033333
-
P53, through p21waf1/cip1, induces cyclin d1 synthesis
-
Chen, X., Bargonetti, J., and Prives, C. (1995) p53, through p21WAF1/CIP1, induces cyclin D1 synthesis. Cancer Res. 55, 4257-4263
-
(1995)
Cancer Res.
, vol.55
, pp. 4257-4263
-
-
Chen, X.1
Bargonetti, J.2
Prives, C.3
-
33
-
-
0032553485
-
Requirement for p53 and p21 to sustain g2 arrest after dna damage
-
Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., and Vogelstein, B. (1998) Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282, 1497-1501
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
34
-
-
0030011128
-
Uncoupling of s phase and mitosis induced by anticancer agents in cells lacking p21
-
Waldman, T., Lengauer, C., Kinzler, K. W., and Vogelstein, B. (1996) Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713-716
-
(1996)
Nature
, vol.381
, pp. 713-716
-
-
Waldman, T.1
Lengauer, C.2
Kinzler, K.W.3
Vogelstein, B.4
-
35
-
-
32044449228
-
Dna polymerase-, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates thedna damage checkpoint and p53 activation
-
Liu, G., and Chen, X. (2006) DNA polymerase-, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates theDNA damage checkpoint and p53 activation. Mol. Cell. Biol. 26, 1398-1413
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1398-1413
-
-
Liu, G.1
Chen, X.2
-
36
-
-
33744940368
-
Tumor suppressor gene-inducible cell lines
-
Dohn, M., Nozell, S., Willis, A., and Chen, X. (2003) Tumor suppressor gene-inducible cell lines. Methods Mol. Biol. 223, 221-235
-
(2003)
Methods Mol. Biol.
, vol.223
, pp. 221-235
-
-
Dohn, M.1
Nozell, S.2
Willis, A.3
Chen, X.4
-
37
-
-
84876927156
-
Mdm2 expression is repressed by the rna-binding protein rnpc1 via mrna stability
-
Xu, E., Zhang, J., and Chen, X. (2013) MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability. Oncogene 32, 2169-2178
-
(2013)
Oncogene
, vol.32
, pp. 2169-2178
-
-
Xu, E.1
Zhang, J.2
Chen, X.3
-
38
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of mdm2
-
Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., Fotouhi, N., and Liu, E. A. (2004) In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303, 844-848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
39
-
-
59249094289
-
Posttranscriptional regulation of p53 and its targets by rna-binding proteins
-
Zhang, J., and Chen, X. (2008) Posttranscriptional regulation of p53 and its targets by RNA-binding proteins. Curr. Mol. Med. 8, 845-849
-
(2008)
Curr. Mol. Med.
, vol.8
, pp. 845-849
-
-
Zhang, J.1
Chen, X.2
-
40
-
-
44949179228
-
Rna recognition motifs: Boring? Not quite
-
Cléry, A., Blatter, M., and Allain, F. H. (2008) RNA recognition motifs: boring? Not quite. Curr. Opin. Struct. Biol. 18, 290-298
-
(2008)
Curr. Opin. Struct. Biol.
, vol.18
, pp. 290-298
-
-
Cléry, A.1
Blatter, M.2
Allain, F.H.3
-
41
-
-
0030965801
-
The cell cycle and cancer
-
Collins, K., Jacks, T., and Pavletich, N. P. (1997) The cell cycle and cancer. Proc. Natl. Acad. Sci. U.S.A. 94, 2776-2778
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 2776-2778
-
-
Collins, K.1
Jacks, T.2
Pavletich, N.P.3
-
42
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein, B., and Kinzler, K. W. (2004) Cancer genes and the pathways they control. Nat. Med. 10, 789-799
-
(2004)
Nat. Med.
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
|