The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements

Journal of Molecular and Cellular Cardiology

Volumn 54, Issue 1, 2013, Pages 90-97

  Hidalgo, Carlos G ^a   Chung, Charles S ^a   Saripalli, Chandra ^a   Methawasin, Mei ^a   Hutchinson, Kirk R ^a   Tsaprailis, George ^a   Labeit, Siegfried ^b   Mattiazzi, Alicia ^c   Granzier, Henk L ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

CaMKII; Diastolic function; Myofilament; Passive stiffness; Regulation; Titin

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II DELTA; CONNECTIN; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PHOSPHOPROTEIN PHOSPHATASE 1; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART LEFT VENTRICLE WALL; HEART MUSCLE ISCHEMIA; HEART MUSCLE TENSION; IN VITRO STUDY; IN VIVO STUDY; ISOLATED HEART; MALE; MOUSE; N2B SPRING ELEMENT; NONHUMAN; PEVK SPRING ELEMENT; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; REPERFUSION INJURY; SKINNED MUSCLE FIBER; TANDEM MASS SPECTROMETRY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CONSERVED SEQUENCE; HEART VENTRICLES; HUMANS; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY;

EID: 84871383473     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.11.012     Document Type: Article

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