메뉴 건너뛰기




Volumn 179, Issue 3, 2015, Pages 454-465

Early dynamics of T helper cell cytokines and T regulatory cells in response to treatment of active Mycobacterium tuberculosis infection

Author keywords

Cytokines; T cells; Tregs; Treatment; Tuberculosis

Indexed keywords

CD147 ANTIGEN; CD161 ANTIGEN; CULTURE FILTRATE PROTEIN 10; CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; TUBERCULOSTATIC AGENT; TUMOR NECROSIS FACTOR ALPHA; ACYLTRANSFERASE; ANTIGEN 85A, MYCOBACTERIUM TUBERCULOSIS; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CFP-10 PROTEIN (71-85), MYCOBACTERIUM TUBERCULOSIS; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; LEUKOCYTE ANTIGEN; PEPTIDE FRAGMENT; PHARMACOLOGICAL BIOMARKER;

EID: 84922800635     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12468     Document Type: Article
Times cited : (36)

References (54)
  • 1
    • 84922787418 scopus 로고    scopus 로고
    • Global Tuberculosis Report. Geneva: WHO; WHO/HTM/TB/2013.13.
    • World Health Organization (WHO). Global Tuberculosis Report. Geneva: WHO; 2013. WHO/HTM/TB/2013.13.
    • (2013)
  • 2
    • 84875595918 scopus 로고    scopus 로고
    • Tuberculosis biomarkers discovery: developments, needs, and challenges
    • Wallis RS, Kim P, Cole S etal. Tuberculosis biomarkers discovery: developments, needs, and challenges. Lancet Infect Dis 2013; 13:362-372.
    • (2013) Lancet Infect Dis , vol.13 , pp. 362-372
    • Wallis, R.S.1    Kim, P.2    Cole, S.3
  • 3
    • 77952542701 scopus 로고    scopus 로고
    • Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis
    • Gandhi NR, Nunn P, Dheda K etal. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Lancet 2010; 375:1830-1843.
    • (2010) Lancet , vol.375 , pp. 1830-1843
    • Gandhi, N.R.1    Nunn, P.2    Dheda, K.3
  • 6
    • 0035064072 scopus 로고    scopus 로고
    • Immunology of tuberculosis
    • Flynn JL, Chan J. Immunology of tuberculosis. Annu Rev Immunol 2001; 19:93-129.
    • (2001) Annu Rev Immunol , vol.19 , pp. 93-129
    • Flynn, J.L.1    Chan, J.2
  • 7
    • 77953274576 scopus 로고    scopus 로고
    • How tumour necrosis factor blockers interfere with tuberculosis immunity
    • Harris J, Keane J. How tumour necrosis factor blockers interfere with tuberculosis immunity. Clin Exp Immunol 2010; 161:1-9.
    • (2010) Clin Exp Immunol , vol.161 , pp. 1-9
    • Harris, J.1    Keane, J.2
  • 8
    • 67649216110 scopus 로고    scopus 로고
    • Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells
    • Lindenstrom T, Agger EM, Korsholm KS etal. Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells. J Immunol 2009; 182:8047-8055.
    • (2009) J Immunol , vol.182 , pp. 8047-8055
    • Lindenstrom, T.1    Agger, E.M.2    Korsholm, K.S.3
  • 9
    • 74249099784 scopus 로고    scopus 로고
    • Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells
    • Scriba TJ, Tameris M, Mansoor N etal. Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells. Eur J Immunol 2010; 40:279-290.
    • (2010) Eur J Immunol , vol.40 , pp. 279-290
    • Scriba, T.J.1    Tameris, M.2    Mansoor, N.3
  • 10
    • 79952449129 scopus 로고    scopus 로고
    • Dominant TNF-alpha+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease
    • Harari A, Rozot V, Enders FB etal. Dominant TNF-alpha+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease. Nat Med 2011; 17:372-376.
    • (2011) Nat Med , vol.17 , pp. 372-376
    • Harari, A.1    Rozot, V.2    Enders, F.B.3
  • 11
    • 77956108181 scopus 로고    scopus 로고
    • Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection
    • Caccamo N, Guggino G, Joosten SA etal. Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection. Eur J Immunol 2010; 40:2211-2220.
    • (2010) Eur J Immunol , vol.40 , pp. 2211-2220
    • Caccamo, N.1    Guggino, G.2    Joosten, S.A.3
  • 12
    • 64049095274 scopus 로고    scopus 로고
    • Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease
    • Sutherland JS, Adetifa IM, Hill PC, Adegbola RA, Ota MO. Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease. Eur J Immunol 2009; 39:723-729.
    • (2009) Eur J Immunol , vol.39 , pp. 723-729
    • Sutherland, J.S.1    Adetifa, I.M.2    Hill, P.C.3    Adegbola, R.A.4    Ota, M.O.5
  • 14
    • 34547957664 scopus 로고    scopus 로고
    • Regulatory T cells depress immune responses to protective antigens in active tuberculosis
    • Hougardy JM, Place S, Hildebrand M etal. Regulatory T cells depress immune responses to protective antigens in active tuberculosis. Am J Respir Crit Care Med 2007; 176:409-416.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 409-416
    • Hougardy, J.M.1    Place, S.2    Hildebrand, M.3
  • 15
    • 79551676026 scopus 로고    scopus 로고
    • T regulatory cells and immune activation in Mycobacterium tuberculosis infection and the effect of preventive therapy
    • Wergeland I, Assmus J, Dyrhol-Riise AM. T regulatory cells and immune activation in Mycobacterium tuberculosis infection and the effect of preventive therapy. Scand J Immunol 2011; 73:234-242.
    • (2011) Scand J Immunol , vol.73 , pp. 234-242
    • Wergeland, I.1    Assmus, J.2    Dyrhol-Riise, A.M.3
  • 17
    • 77952877802 scopus 로고    scopus 로고
    • T regulatory cells and Th1/Th2 cytokines in peripheral blood from tuberculosis patients
    • He XY, Xiao L, Chen HB etal. T regulatory cells and Th1/Th2 cytokines in peripheral blood from tuberculosis patients. Eur J Clin Microbiol Infect Dis 2010; 29:643-650.
    • (2010) Eur J Clin Microbiol Infect Dis , vol.29 , pp. 643-650
    • He, X.Y.1    Xiao, L.2    Chen, H.B.3
  • 18
    • 34347232370 scopus 로고    scopus 로고
    • Intracellular cytokine optimization and standard operating procedure
    • Lamoreaux L, Roederer M, Koup R. Intracellular cytokine optimization and standard operating procedure. Nat Protoc 2006; 1:1507-1516.
    • (2006) Nat Protoc , vol.1 , pp. 1507-1516
    • Lamoreaux, L.1    Roederer, M.2    Koup, R.3
  • 19
    • 79956265736 scopus 로고    scopus 로고
    • Multiparameter intracellular cytokine staining
    • In: Hawley TS, Hawley RG, eds. New York: Humana Press
    • Lovelace P, Maecker H. Multiparameter intracellular cytokine staining. In: Hawley TS, Hawley RG, eds. Flow cytometry protocols. New York: Humana Press, 2011:165-178.
    • (2011) Flow cytometry protocols , pp. 165-178
    • Lovelace, P.1    Maecker, H.2
  • 20
    • 79251515158 scopus 로고    scopus 로고
    • SPICE: exploration and analysis of post-cytometric complex multivariate datasets
    • Roederer M, Nozzi JL, Nason MC. SPICE: exploration and analysis of post-cytometric complex multivariate datasets. Cytometry A 2011; 79A:167-174.
    • (2011) Cytometry A , vol.79 , pp. 167-174
    • Roederer, M.1    Nozzi, J.L.2    Nason, M.C.3
  • 21
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Treg cells
    • Liu W, Putnam AL, Xu-Yu Z etal. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Treg cells. J Exp Med 2006; 203:1701-1711.
    • (2006) J Exp Med , vol.203 , pp. 1701-1711
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3
  • 22
    • 81055148068 scopus 로고    scopus 로고
    • CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells
    • Solstad T. CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells. Blood 2011; 118:5141-5151.
    • (2011) Blood , vol.118 , pp. 5141-5151
    • Solstad, T.1
  • 23
    • 84877275454 scopus 로고    scopus 로고
    • CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines
    • Pesenacker AM, Bending D, Ursu S, Wu Q, Nistala K, Wedderburn LR. CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines. Blood 2013; 121:2647-2658.
    • (2013) Blood , vol.121 , pp. 2647-2658
    • Pesenacker, A.M.1    Bending, D.2    Ursu, S.3    Wu, Q.4    Nistala, K.5    Wedderburn, L.R.6
  • 24
    • 66149151399 scopus 로고    scopus 로고
    • Characterization of regulatory T cells identified as CD4+CD25highCD39+ in patients with active tuberculosis
    • Chiacchio T, Casetti R, Butera O etal. Characterization of regulatory T cells identified as CD4+CD25highCD39+ in patients with active tuberculosis. Clin Exp Immunol 2009; 156:463-470.
    • (2009) Clin Exp Immunol , vol.156 , pp. 463-470
    • Chiacchio, T.1    Casetti, R.2    Butera, O.3
  • 25
    • 77956131187 scopus 로고    scopus 로고
    • Increased IgG1, IFN-gamma, TNF-alpha and IL-6 responses to Mycobacterium tuberculosis antigens in patients with tuberculosis are lower after chemotherapy
    • Mattos AM, Almeida Cde S, Franken KL etal. Increased IgG1, IFN-gamma, TNF-alpha and IL-6 responses to Mycobacterium tuberculosis antigens in patients with tuberculosis are lower after chemotherapy. Int Immunol 2010; 22:775-782.
    • (2010) Int Immunol , vol.22 , pp. 775-782
    • Mattos, A.M.1    Almeida Cde, S.2    Franken, K.L.3
  • 26
    • 34547864228 scopus 로고    scopus 로고
    • Changes in the kinetics of intracellular IFN-gamma production in TB patients during treatment
    • Veenstra H, Crous I, Brahmbhatt S etal. Changes in the kinetics of intracellular IFN-gamma production in TB patients during treatment. Clin Immunol 2007; 124:336-344.
    • (2007) Clin Immunol , vol.124 , pp. 336-344
    • Veenstra, H.1    Crous, I.2    Brahmbhatt, S.3
  • 27
    • 80052653924 scopus 로고    scopus 로고
    • Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load
    • Day CL, Abrahams DA, Lerumo L etal. Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load. J Immunol 2011; 187:2222-2232.
    • (2011) J Immunol , vol.187 , pp. 2222-2232
    • Day, C.L.1    Abrahams, D.A.2    Lerumo, L.3
  • 29
    • 84874568830 scopus 로고    scopus 로고
    • Early specific host response associated with starting effective tuberculosis treatment in an infection controlled placebo controlled mouse study
    • den Hertog AL, de Vos AF, Klatser PR, Anthony RM. Early specific host response associated with starting effective tuberculosis treatment in an infection controlled placebo controlled mouse study. PLOS ONE 2013; 8:e57997.
    • (2013) PLOS ONE , vol.8 , pp. e57997
    • den Hertog, A.L.1    de Vos, A.F.2    Klatser, P.R.3    Anthony, R.M.4
  • 30
    • 84879513164 scopus 로고    scopus 로고
    • Recombinant ESAT-6-CFP10 fusion protein induction of Th1/Th2 cytokines and FoxP3 expressing Treg cells in pulmonary TB
    • Jackson-Sillah D, Cliff JM, Mensah GI etal. Recombinant ESAT-6-CFP10 fusion protein induction of Th1/Th2 cytokines and FoxP3 expressing Treg cells in pulmonary TB. PLOS ONE 2013; 8:e68121.
    • (2013) PLOS ONE , vol.8 , pp. e68121
    • Jackson-Sillah, D.1    Cliff, J.M.2    Mensah, G.I.3
  • 31
    • 84860780826 scopus 로고    scopus 로고
    • Utility of interferon-gamma release assay results to monitor anti-tubercular treatment in adults and children
    • Chiappini E, Fossi F, Bonsignori F, Sollai S, Galli L, de Martino M. Utility of interferon-gamma release assay results to monitor anti-tubercular treatment in adults and children. Clin Ther 2012; 34:1041-1048.
    • (2012) Clin Ther , vol.34 , pp. 1041-1048
    • Chiappini, E.1    Fossi, F.2    Bonsignori, F.3    Sollai, S.4    Galli, L.5    de Martino, M.6
  • 32
    • 79952677009 scopus 로고    scopus 로고
    • Whole-blood flow-cytometric analysis of antigen-specific CD4 T-cell cytokine profiles distinguishes active tuberculosis from non-active states
    • Sester U, Fousse M, Dirks J etal. Whole-blood flow-cytometric analysis of antigen-specific CD4 T-cell cytokine profiles distinguishes active tuberculosis from non-active states. PLOS ONE 2011; 6:e17813.
    • (2011) PLOS ONE , vol.6 , pp. e17813
    • Sester, U.1    Fousse, M.2    Dirks, J.3
  • 33
    • 84871249884 scopus 로고    scopus 로고
    • The phenotypic distribution and functional profile of tuberculin-specific CD4 T-cells characterizes different stages of TB infection
    • Streitz M, Fuhrmann S, Thomas D etal. The phenotypic distribution and functional profile of tuberculin-specific CD4 T-cells characterizes different stages of TB infection. Cytometry B Clin Cytom 2012; 82:360-368.
    • (2012) Cytometry B Clin Cytom , vol.82 , pp. 360-368
    • Streitz, M.1    Fuhrmann, S.2    Thomas, D.3
  • 34
    • 84876836834 scopus 로고    scopus 로고
    • IFNgamma/TNFalpha specific-cells and effector memory phenotype associate with active tuberculosis
    • Petruccioli E, Petrone L, Vanini V etal. IFNgamma/TNFalpha specific-cells and effector memory phenotype associate with active tuberculosis. J Infect 2013; 66:475-486.
    • (2013) J Infect , vol.66 , pp. 475-486
    • Petruccioli, E.1    Petrone, L.2    Vanini, V.3
  • 35
    • 84922831094 scopus 로고    scopus 로고
    • Polyfunctional T-cells and effector memory phenotype are associated with active TB in HIV-infected patients
    • [Epub ahead of print].
    • Chiacchio T, Petruccioli E, Vanini V etal. Polyfunctional T-cells and effector memory phenotype are associated with active TB in HIV-infected patients. J Infect 2014. doi: 10.1016/j.jinf.2014.06.009. [Epub ahead of print].
    • (2014) J Infect
    • Chiacchio, T.1    Petruccioli, E.2    Vanini, V.3
  • 36
    • 42549163830 scopus 로고    scopus 로고
    • Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons
    • Day CL, Mkhwanazi N, Reddy S etal. Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons. J Infect Dis 2008; 197:990-999.
    • (2008) J Infect Dis , vol.197 , pp. 990-999
    • Day, C.L.1    Mkhwanazi, N.2    Reddy, S.3
  • 37
    • 34247137553 scopus 로고    scopus 로고
    • Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load
    • Millington KA, Innes JA, Hackforth S etal. Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load. J Immunol 2007; 178:5217-5226.
    • (2007) J Immunol , vol.178 , pp. 5217-5226
    • Millington, K.A.1    Innes, J.A.2    Hackforth, S.3
  • 38
    • 77955301737 scopus 로고    scopus 로고
    • Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment
    • Young JM, Adetifa IM, Ota MO, Sutherland JS. Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment. PLOS ONE 2010; 5:e11237.
    • (2010) PLOS ONE , vol.5 , pp. e11237
    • Young, J.M.1    Adetifa, I.M.2    Ota, M.O.3    Sutherland, J.S.4
  • 39
    • 84865792720 scopus 로고    scopus 로고
    • New pathways of protective and pathological host defense to mycobacteria
    • Ottenhoff TH. New pathways of protective and pathological host defense to mycobacteria. Trends Microbiol 2012; 20:419-428.
    • (2012) Trends Microbiol , vol.20 , pp. 419-428
    • Ottenhoff, T.H.1
  • 40
    • 67650735181 scopus 로고    scopus 로고
    • Differential cytokine/chemokines and KL-6 profiles in patients with different forms of tuberculosis
    • Djoba Siawaya JF, Chegou NN, van den Heuvel MM etal. Differential cytokine/chemokines and KL-6 profiles in patients with different forms of tuberculosis. Cytokine 2009; 47:132-136.
    • (2009) Cytokine , vol.47 , pp. 132-136
    • Djoba Siawaya, J.F.1    Chegou, N.N.2    van den Heuvel, M.M.3
  • 41
    • 0142185336 scopus 로고    scopus 로고
    • Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
    • Betts MR, Brenchley JM, Price DA etal. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 2003; 281:65-78.
    • (2003) J Immunol Methods , vol.281 , pp. 65-78
    • Betts, M.R.1    Brenchley, J.M.2    Price, D.A.3
  • 42
    • 84856000776 scopus 로고    scopus 로고
    • The influence of bacille Calmette-Guerin vaccine strain on the immune response against tuberculosis: a randomized trial
    • Ritz N, Dutta B, Donath S etal. The influence of bacille Calmette-Guerin vaccine strain on the immune response against tuberculosis: a randomized trial. Am J Respir Crit Care Med 2012; 185:213-222.
    • (2012) Am J Respir Crit Care Med , vol.185 , pp. 213-222
    • Ritz, N.1    Dutta, B.2    Donath, S.3
  • 43
    • 84455192424 scopus 로고    scopus 로고
    • Granulysin-expressing CD4+ T cells as candidate immune marker for tuberculosis during childhood and adolescence
    • Mueller H, Fae KC, Magdorf K etal. Granulysin-expressing CD4+ T cells as candidate immune marker for tuberculosis during childhood and adolescence. PLOS ONE 2011; 6:e29367.
    • (2011) PLOS ONE , vol.6 , pp. e29367
    • Mueller, H.1    Fae, K.C.2    Magdorf, K.3
  • 44
    • 84878956249 scopus 로고    scopus 로고
    • Regulatory T cells attenuate mycobacterial stasis in alveolar and blood-derived macrophages from patients with tuberculosis
    • Semple PL, Binder AB, Davids M, Maredza A, van Zyl-Smit RN, Dheda K. Regulatory T cells attenuate mycobacterial stasis in alveolar and blood-derived macrophages from patients with tuberculosis. Am J Respir Crit Care Med 2013; 187:1249-1258.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 1249-1258
    • Semple, P.L.1    Binder, A.B.2    Davids, M.3    Maredza, A.4    van Zyl-Smit, R.N.5    Dheda, K.6
  • 45
    • 33847344205 scopus 로고    scopus 로고
    • Cutting Edge: regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis
    • Kursar M, Koch M, Mittrucker HW etal. Cutting Edge: regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis. J Immunol 2007; 178:2661-2665.
    • (2007) J Immunol , vol.178 , pp. 2661-2665
    • Kursar, M.1    Koch, M.2    Mittrucker, H.W.3
  • 46
    • 33947253487 scopus 로고    scopus 로고
    • CD4(+)CD25(+)FoxP3(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease
    • Chen X, Zhou B, Li M etal. CD4(+)CD25(+)FoxP3(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease. Clin Immunol 2007; 123:50-59.
    • (2007) Clin Immunol , vol.123 , pp. 50-59
    • Chen, X.1    Zhou, B.2    Li, M.3
  • 47
    • 77955717510 scopus 로고    scopus 로고
    • Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis
    • Marin ND, Paris SC, Velez VM, Rojas CA, Rojas M, Garcia LF. Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis. Tuberculosis (Edinb) 2010; 90:252-261.
    • (2010) Tuberculosis (Edinb) , vol.90 , pp. 252-261
    • Marin, N.D.1    Paris, S.C.2    Velez, V.M.3    Rojas, C.A.4    Rojas, M.5    Garcia, L.F.6
  • 48
    • 84855668117 scopus 로고    scopus 로고
    • Increased frequency of regulatory T cells and T lymphocyte activation in persons with previously treated extrapulmonary tuberculosis
    • de Almeida AS, Fiske CT, Sterling TR, Kalams SA. Increased frequency of regulatory T cells and T lymphocyte activation in persons with previously treated extrapulmonary tuberculosis. Clin Vaccine Immunol 2012; 19:45-52.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 45-52
    • de Almeida, A.S.1    Fiske, C.T.2    Sterling, T.R.3    Kalams, S.A.4
  • 49
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy KJ, Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol 2001; 2:816-822.
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 50
    • 78349232055 scopus 로고    scopus 로고
    • Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype
    • Dwyer KM, Hanidziar D, Putheti P etal. Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype. Am J Transplant 2010; 10:2410-2420.
    • (2010) Am J Transplant , vol.10 , pp. 2410-2420
    • Dwyer, K.M.1    Hanidziar, D.2    Putheti, P.3
  • 51
    • 84879604666 scopus 로고    scopus 로고
    • Pathogen-specific Treg cells expand early during Mycobacterium tuberculosis infection but are later eliminated in response to interleukin-12
    • Shafiani S, Dinh C, Ertelt JM etal. Pathogen-specific Treg cells expand early during Mycobacterium tuberculosis infection but are later eliminated in response to interleukin-12. Immunity 2013; 38:1261-1270.
    • (2013) Immunity , vol.38 , pp. 1261-1270
    • Shafiani, S.1    Dinh, C.2    Ertelt, J.M.3
  • 52
    • 61849099439 scopus 로고    scopus 로고
    • Differential cytokine secretion and early treatment response in patients with pulmonary tuberculosis
    • Djoba Siawaya JF, Beyers N, van Helden P, Walzl G. Differential cytokine secretion and early treatment response in patients with pulmonary tuberculosis. Clin Exp Immunol 2009; 156:69-77.
    • (2009) Clin Exp Immunol , vol.156 , pp. 69-77
    • Djoba Siawaya, J.F.1    Beyers, N.2    van Helden, P.3    Walzl, G.4
  • 53
    • 80755159593 scopus 로고    scopus 로고
    • Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood
    • Chiacchio T, Petruccioli E, Vanini V etal. Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood. PLOS ONE 2011; 6:e27539.
    • (2011) PLOS ONE , vol.6 , pp. e27539
    • Chiacchio, T.1    Petruccioli, E.2    Vanini, V.3
  • 54
    • 79955698216 scopus 로고    scopus 로고
    • Polyfunctional Mycobacterium tuberculosis-specific effector memory CD4+ T cells at sites of pleural TB
    • El Fenniri L, Toossi Z, Aung H etal. Polyfunctional Mycobacterium tuberculosis-specific effector memory CD4+ T cells at sites of pleural TB. Tuberculosis (Edinb) 2011; 91:224-230.
    • (2011) Tuberculosis (Edinb) , vol.91 , pp. 224-230
    • El Fenniri, L.1    Toossi, Z.2    Aung, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.