Regulatory T cells attenuate mycobacterial stasis in alveolar and blood-derived macrophages from patients with tuberculosis

American Journal of Respiratory and Critical Care Medicine

Volumn 187, Issue 11, 2013, Pages 1249-1258

  Semple, Patricia L ^a   Binder, Anke B ^a   Davids, Malika ^a   Maredza, Alice ^a   Van Zyl Smit, Richard N ^a   Dheda, Keertan ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Bronchoalveolar lavage; FoxP3; Mycobacterial stasis; Natural regulatory T cells; Pulmonary tuberculosis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 22; TRANSCRIPTION FACTOR FOXP3; TUBERCULIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BACTERIAL GROWTH; BLOOD DONOR; BRONCHOSCOPY; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CELL FUNCTION; CELL PROLIFERATION; CLINICAL ARTICLE; COCULTURE; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LATENT TUBERCULOSIS; LUNG ALVEOLUS; LUNG LAVAGE; LUNG TUBERCULOSIS; MACROPHAGE; MONOCYTE; MYCOBACTERIUM TUBERCULOSIS; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T CELL DEPLETION; TH1 CELL; TH17 CELL; TH2 CELL;

ANTIGENS, BACTERIAL; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOKINES; HUMANS; IMMUNITY, CELLULAR; MACROPHAGES; MYCOBACTERIUM TUBERCULOSIS; T-LYMPHOCYTES, REGULATORY; TUBERCULOSIS, PULMONARY;

EID: 84878956249     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201210-1934OC     Document Type: Article

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