Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines and FoxP3 Expressing Treg Cells in Pulmonary TB

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Jackson Sillah, Dolly ^a,c   Cliff, Jacqueline M ^a   Mensah, Gloria Ivy ^c   Dickson, Emmanuel ^c   Sowah, Sandra ^c   Tetteh, John K A ^c   Addo, Kwasi K ^c   Ottenhoff, Tom H M ^b   Bothamley, Graham ^d   Dockrell, Hazel M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c University of Ghana   (Ghana)

^d HOMERTON UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; ETHAMBUTOL PLUS ISONIAZID PLUS PYRAZINAMIDE PLUS RIFAMPICIN; GAMMA INTERFERON; HYBRID PROTEIN; INTERLEUKIN 4; ISONIAZID PLUS RIFAMPICIN; TRANSCRIPTION FACTOR FOXP3; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; BCG VACCINE; CFP17 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; NEGATIVE ELONGATION FACTOR; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR;

ADULT; AGED; ARTICLE; CELL CULTURE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSPOT ASSAY; EX VIVO STUDY; FEMALE; GHANA; HUMAN; HUMAN CELL; IMMUNOLOGICAL PARAMETERS; IN VITRO STUDY; LUNG TUBERCULOSIS; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; PATIENT SELECTION; PERIPHERAL BLOOD MONONUCLEAR CELL; REGULATORY T LYMPHOCYTE; TH1 CELL; TH2 CELL; UNITED KINGDOM; ADOLESCENT; CLINICAL TRIAL; IMMUNOLOGY; LONGITUDINAL STUDY; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; MULTICENTER STUDY; TUBERCULOSIS, PULMONARY; YOUNG ADULT;

MYCOBACTERIUM TUBERCULOSIS;

ADOLESCENT; ADULT; AGED; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BCG VACCINE; CELLS, CULTURED; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GHANA; HUMANS; LEUKOCYTES, MONONUCLEAR; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; RECOMBINANT PROTEINS; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTION FACTORS; TUBERCULOSIS, PULMONARY; UNITED KINGDOM; YOUNG ADULT;

EID: 84879513164     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068121     Document Type: Article

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