Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host

Science

Volumn 337, Issue 6093, 2012, Pages 463-466

  Salmon, Didier ^a,b   Vanwalleghem, Gilles ^a   Morias, Yannick ^c,d   Denoeud, Julie ^a   Krumbholz, Carsten ^e   Lhommé, Frédéric ^f   Bachmaier, Sabine ^e   Kador, Markus ^e   Gossmann, Jasmin ^e   Dias, Fernando Braga Stehling ^a,b   De Muylder, Géraldine ^a   Uzureau, Pierrick ^a   Magez, Stefan ^c,d   Moser, Muriel ^a   De Baetselier, Patrick ^c,d   Van Den Abbeele, Jan ^g   Beschin, Alain ^c,d   Boshart, Michael ^e   Pays, Etienne ^a,h  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^e UNIVERSITY OF MUNICH   (Germany)

^f Center for Microscopy and Molecular Imaging   (Belgium)

^g INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^h Walloon Excellence in Life Sciences and Biotechnology (WELBIO)   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA; VARIANT SURFACE GLYCOPROTEIN;

COLONIZATION; ENZYME ACTIVITY; GENETIC ANALYSIS; IMMUNE RESPONSE; POLYMORPHISM; PROTEIN; PROTOZOAN;

ARTICLE; ENZYME ACTIVATION; HOST; HOST PARASITE INTERACTION; INNATE IMMUNITY; MICROBIAL COLONIZATION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SPLENECTOMY; SURVIVAL TIME; TRYPANOSOMA BRUCEI;

TRYPANOSOMA BRUCEI;

EID: 84864344932     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1222753     Document Type: Article

References (28)

1. E. Pays, L. Vanhamme, D. Pérez-Morga, Curr. Opin. Microbiol. 7, 369 (2004).
2. S. Rolin et al., J. Biol. Chem. 271, 10844 (1996).
3. S. Magez et al., J. Immunol. 160, 1949 (1998).
4. J. M. Mansfield, D. M. Paulnock, Parasite Immunol. 27, 361 (2005).
5. S. Magez, M. Radwanska, A. Beschin, K. Sekikawa, P. De Baetselier, Infect. Immun. 67, 3128 (1999).
6. M. Guilliams et al., J. Immunol. 182, 1107 (2009).
7. S. Magez, B. Stijlemans, T. Baral, P. De Baetselier, Microbes Infect. 4, 999 (2002).
8. S. Alexandre et al., Mol. Biochem. Parasitol. 77, 173 (1996).
9. D. J. Bridges et al., Proteomics 8, 83 (2008).
10. D. Salmon et al., Mol. Microbiol. 84, 225 (2012).
11. E. Pays et al., Cell 57, 835 (1989).
12. S. Alexandre et al., Mol. Biochem. Parasitol. 43, 279 (1990).
13. C. Naula, R. Schaub, V. Leech, S. Melville, T. Seebeck, Mol. Biochem. Parasitol. 112, 19 (2001).
14. T. Seebeck, R. Schaub, A. Johner, Curr. Mol. Med. 4, 585 (2004).
15. H. P. Voorheis, B. R. Martin, Eur. J. Biochem. 113, 223 (1980).
16. B. Bieger, L. O. Essen, EMBO J. 20, 433 (2001).
17. P. Paindavoine et al., Mol. Cell. Biol. 12, 1218 (1992).
18. L. Lecordier et al., Mol. Biochem. Parasitol. 140, 127 (2005).
19. N. Van Rooijen, A. Sanders, J. Immunol. Methods 174, 83 (1994).
20. W. L. Dempsey, J. M. Mansfield, J. Immunol. 130, 405 (1983).
21. E. A. Wall et al., Sci. Signal. 2, ra28 (2009).
22. B. S. Willis, C. M. Niswender, T. Su, P. S. Amieux, G. S. McKnight, PLoS ONE 6, e18772 (2011).
23. G. Wei, H. Bull, X. Zhou, H. Tabel, J. Infect. Dis. 203, 418 (2011).
24. K. A. McDonough, A. Rodriguez, Nat. Rev. Microbiol. 10, 27 (2012).
25. N. Agarwal, G. Lamichhane, R. Gupta, S. Nolan,W. R. Bishai, Nature 460, 98 (2009).
26. J. Cui, S. Das, T. F. Smith, J. Samuelson, PLoS Negl. Trop. Dis. 4, e782 (2010).
27. L. Ratier et al., PLoS ONE 3, e3524 (2008).
28. J. P. J. Saeij et al., Science 314, 1780 (2006).