A vaccine formulation combining rhoptry proteins NcROP40 and NcROP2 improves pup survival in a pregnant mouse model of neosporosis

Veterinary Parasitology

Volumn 207, Issue 3-4, 2015, Pages 203-215

  Pastor Fernández, Iván ^a   Arranz Solís, David ^a   Regidor Cerrillo, Javier ^a   Álvarez García, Gema ^a   Hemphill, Andrew ^b   García Culebras, Alicia ^a   Cuevas Martín, Carmen ^a   Ortega Mora, Luis M ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b VETSUISSE FACULTY UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

NcGRA7; NcNTPase; NcROP2; NcROP40; Neospora caninum vaccine; Pregnant mouse model

Indexed keywords

DNA; GAMMA INTERFERON; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 4; PARASITE ANTIGEN; PROTOZOAL VACCINE; RECOMBINANT ANTIGEN; RECOMBINANT NCGRA7 VACCINE; RECOMBINANT NCNTPASE VACCINE; RECOMBINANT NCROP2 VACCINE; RECOMBINANT NCROP40 VACCINE; RECOMBINANT VACCINE; UNCLASSIFIED DRUG; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; RECOMBINANT PROTEIN;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; CELL ORGANELLE; CELLULAR IMMUNITY; CEREBRAL PARASITE INFECTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CUB; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; FEMALE; FEMALE FERTILITY; FEVER; GROWTH RETARDATION; HUMORAL IMMUNITY; IMMUNIZATION; INFECTION PREVENTION; MONOTHERAPY; MORBIDITY; MOUSE; NEOSPORA CANINUM; NEOSPOROSIS; NEWBORN MORTALITY; NONHUMAN; PARASITE ISOLATION; PARASITE LOAD; PARASITE VIRULENCE; PARASITOSIS; PARESIS; POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY COMPLICATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RHOPTRY; SKIN NODULE; SURVIVAL; SURVIVAL RATE; SURVIVAL TIME; TACHYZOITE; VERTICAL TRANSMISSION; WEIGHT REDUCTION; ANIMAL; BLOOD; COCCIDIOSIS; DISEASE MODEL; IMMUNOLOGY; MORTALITY; NEOSPORA; PHYSIOLOGY; PREVENTION AND CONTROL; STANDARDS;

BOVINAE; MUS; NEOSPORA CANINUM;

ANIMALS; ANTIBODIES, PROTOZOAN; COCCIDIOSIS; DISEASE MODELS, ANIMAL; FEMALE; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MICE; NEOSPORA; PREGNANCY; PROTOZOAN PROTEINS; PROTOZOAN VACCINES; RECOMBINANT PROTEINS; SURVIVAL ANALYSIS;

EID: 84922696350     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2014.12.009     Document Type: Article

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