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Volumn 123, Issue 1, 2009, Pages 81-89

Toxoplasma gondii: The immunogenic and protective efficacy of recombinant ROP2 and ROP4 rhoptry proteins in murine experimental toxoplasmosis

Author keywords

Immunoprotection; Recombinant ROP2; Recombinant ROP4; Subunit vaccines; Toxoplasma gondii

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL VACCINE; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G1; INTERLEUKIN 2; RECOMBINANT ROP2 ANTIGEN; RECOMBINANT ROP4 ANTIGEN; UNCLASSIFIED DRUG;

EID: 67949107942     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2009.06.002     Document Type: Article
Times cited : (50)

References (48)
  • 3
    • 0029042137 scopus 로고
    • A commercial vaccine for ovine toxoplasmosis
    • Buxton D., and Innes E.A. A commercial vaccine for ovine toxoplasmosis. Parasitology 110 (1995) 11-16
    • (1995) Parasitology , vol.110 , pp. 11-16
    • Buxton, D.1    Innes, E.A.2
  • 4
    • 0025349748 scopus 로고
    • Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens
    • Chardes T., Bourguin I., Mevelec M.N., Dubremetz J.F., and Bout D. Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens. Infection and Immunity 58 (1990) 1240-1246
    • (1990) Infection and Immunity , vol.58 , pp. 1240-1246
    • Chardes, T.1    Bourguin, I.2    Mevelec, M.N.3    Dubremetz, J.F.4    Bout, D.5
  • 5
    • 0032718790 scopus 로고    scopus 로고
    • T lymphocyte-dependent effector mechanisms of immunity to Toxoplasma gondii
    • Denkers E.Y. T lymphocyte-dependent effector mechanisms of immunity to Toxoplasma gondii. Microbes and Infection 1 (1999) 699-708
    • (1999) Microbes and Infection , vol.1 , pp. 699-708
    • Denkers, E.Y.1
  • 6
    • 0031736936 scopus 로고    scopus 로고
    • Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection
    • Denkers E.Y., and Gazzinelli R.T. Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clinical Microbiology Reviews 11 (1998) 569-588
    • (1998) Clinical Microbiology Reviews , vol.11 , pp. 569-588
    • Denkers, E.Y.1    Gazzinelli, R.T.2
  • 9
    • 33947109437 scopus 로고    scopus 로고
    • Rhoptries are major players in Toxoplasma gondii invasion and host cell interaction
    • Dubremetz J.F. Rhoptries are major players in Toxoplasma gondii invasion and host cell interaction. Cellular Microbiology 9 (2007) 841-848
    • (2007) Cellular Microbiology , vol.9 , pp. 841-848
    • Dubremetz, J.F.1
  • 10
    • 34548568164 scopus 로고    scopus 로고
    • Identification of Toxoplasma gondii proteins binding human lactoferrin: a new aspect of rhoptry proteins function
    • Dziadek B., Dziadek J., and Dlugonska H. Identification of Toxoplasma gondii proteins binding human lactoferrin: a new aspect of rhoptry proteins function. Experimental Parasitology 115 (2007) 277-282
    • (2007) Experimental Parasitology , vol.115 , pp. 277-282
    • Dziadek, B.1    Dziadek, J.2    Dlugonska, H.3
  • 11
    • 33646469572 scopus 로고    scopus 로고
    • Potent antigen-specific immunity to Toxoplasma gondii in adjuvant-free vaccination system using Rop2-Leishmania infantum Hsp83 fusion protein
    • Echeverria P.C., De Miguel N., Costas M., and Angel S.O. Potent antigen-specific immunity to Toxoplasma gondii in adjuvant-free vaccination system using Rop2-Leishmania infantum Hsp83 fusion protein. Vaccine 24 (2006) 4102-4110
    • (2006) Vaccine , vol.24 , pp. 4102-4110
    • Echeverria, P.C.1    De Miguel, N.2    Costas, M.3    Angel, S.O.4
  • 14
    • 37349012151 scopus 로고    scopus 로고
    • Toxoplasma gondii: Chimeric Dr fimbriae as a recombinant vaccine against toxoplasmosis
    • Gatkowska J., Gasior A., Kur J., and Dlugonska H. Toxoplasma gondii: Chimeric Dr fimbriae as a recombinant vaccine against toxoplasmosis. Experimental Parasitology 118 (2008) 266-270
    • (2008) Experimental Parasitology , vol.118 , pp. 266-270
    • Gatkowska, J.1    Gasior, A.2    Kur, J.3    Dlugonska, H.4
  • 15
    • 34247512000 scopus 로고    scopus 로고
    • Evaluation of protective effect of recombinant dense granule antigens GRA2 and GRA6 formulated in monophosphoryl lipid A (MPL) adjuvant against Toxoplasma chronic infection in mice
    • Golkar M., Shokrgozar M.A., Rafati S., Musset K., Assmar M., Sadaie R., Cesbron-Delauw M.F., and Mercier C. Evaluation of protective effect of recombinant dense granule antigens GRA2 and GRA6 formulated in monophosphoryl lipid A (MPL) adjuvant against Toxoplasma chronic infection in mice. Vaccine 25 (2007) 4301-4311
    • (2007) Vaccine , vol.25 , pp. 4301-4311
    • Golkar, M.1    Shokrgozar, M.A.2    Rafati, S.3    Musset, K.4    Assmar, M.5    Sadaie, R.6    Cesbron-Delauw, M.F.7    Mercier, C.8
  • 16
    • 0036803121 scopus 로고    scopus 로고
    • Toxoplasma gondii: transmission, diagnosis and prevention
    • Hill D., and Dubey J.P. Toxoplasma gondii: transmission, diagnosis and prevention. Clinical Microbiology and Infection 8 (2002) 634-640
    • (2002) Clinical Microbiology and Infection , vol.8 , pp. 634-640
    • Hill, D.1    Dubey, J.P.2
  • 18
    • 33846811391 scopus 로고    scopus 로고
    • Vaccination as a control strategy against the coccidial parasites Eimeria, Toxoplasma and Neospora
    • Innes E.A., and Vermeulen A.N. Vaccination as a control strategy against the coccidial parasites Eimeria, Toxoplasma and Neospora. Parasitology 133 (2006) 145-168
    • (2006) Parasitology , vol.133 , pp. 145-168
    • Innes, E.A.1    Vermeulen, A.N.2
  • 19
    • 50849142871 scopus 로고    scopus 로고
    • Protective Th1 immune responses against chronic toxoplasmosis induced by a protein-protein vaccine combination but not by its DNA-protein counterpart
    • Jongert E., Verhelst D., Abady M., Petersen E., and Gargano N. Protective Th1 immune responses against chronic toxoplasmosis induced by a protein-protein vaccine combination but not by its DNA-protein counterpart. Vaccine 26 (2008) 5289-5295
    • (2008) Vaccine , vol.26 , pp. 5289-5295
    • Jongert, E.1    Verhelst, D.2    Abady, M.3    Petersen, E.4    Gargano, N.5
  • 20
    • 0034161721 scopus 로고    scopus 로고
    • Decreased resistance of B cell-deficient mice to infection with Toxoplasma gondii despite unimpaired expression of IFN-γ, TNF-α, and inducible nitric oxide synthase
    • Kang H., Remington J.S., and Suzuki Y. Decreased resistance of B cell-deficient mice to infection with Toxoplasma gondii despite unimpaired expression of IFN-γ, TNF-α, and inducible nitric oxide synthase. The Journal of Immunology 164 (2000) 2629-2634
    • (2000) The Journal of Immunology , vol.164 , pp. 2629-2634
    • Kang, H.1    Remington, J.S.2    Suzuki, Y.3
  • 21
    • 51449108123 scopus 로고    scopus 로고
    • Control of the risk of human toxoplasmosis transmitted by meat
    • Kijlstra A., and Jongert E. Control of the risk of human toxoplasmosis transmitted by meat. International Journal for Parasitology 38 (2008) 1359-1370
    • (2008) International Journal for Parasitology , vol.38 , pp. 1359-1370
    • Kijlstra, A.1    Jongert, E.2
  • 22
    • 0031710771 scopus 로고    scopus 로고
    • Protective effect of vaccination with a combination of recombinant surface antigen 1 and interleukin-12 against toxoplasmosis in mice
    • Letscher-Bru V., Villard O., Risse B., Zauke M., Klein J.P., and Kien T. Protective effect of vaccination with a combination of recombinant surface antigen 1 and interleukin-12 against toxoplasmosis in mice. Infection and Immunity 66 (1998) 4503-4506
    • (1998) Infection and Immunity , vol.66 , pp. 4503-4506
    • Letscher-Bru, V.1    Villard, O.2    Risse, B.3    Zauke, M.4    Klein, J.P.5    Kien, T.6
  • 24
    • 0034910058 scopus 로고    scopus 로고
    • Genetic immunization with plasmid DNA coding the ROP2 protein of Toxoplasma gondii
    • Leyva R., Herion P., and Saavedra R. Genetic immunization with plasmid DNA coding the ROP2 protein of Toxoplasma gondii. Parasitology Research 87 (2001) 70-79
    • (2001) Parasitology Research , vol.87 , pp. 70-79
    • Leyva, R.1    Herion, P.2    Saavedra, R.3
  • 28
    • 0031921785 scopus 로고    scopus 로고
    • Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route
    • Mevelec M.N., Mercereau-Puijalon O., Buzoni-Gatel D., Bourguin J., Chardes T., Dubremetz J.F., and Bout D. Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route. Parasite Immunology 20 (1998) 183-195
    • (1998) Parasite Immunology , vol.20 , pp. 183-195
    • Mevelec, M.N.1    Mercereau-Puijalon, O.2    Buzoni-Gatel, D.3    Bourguin, J.4    Chardes, T.5    Dubremetz, J.F.6    Bout, D.7
  • 30
    • 0035321583 scopus 로고    scopus 로고
    • Modified protection against Toxoplasma gondii lethal infection and brain cyst formation by vaccination with SAG2 and SRS1
    • Mishima M., Xuan X., Shioda A., Omata Y., Fujisaki K., Nagasawa H., and Mikami T. Modified protection against Toxoplasma gondii lethal infection and brain cyst formation by vaccination with SAG2 and SRS1. Parasitology 63 (2001) 433-438
    • (2001) Parasitology , vol.63 , pp. 433-438
    • Mishima, M.1    Xuan, X.2    Shioda, A.3    Omata, Y.4    Fujisaki, K.5    Nagasawa, H.6    Mikami, T.7
  • 31
    • 0037672558 scopus 로고    scopus 로고
    • Pleiotropic effect due to targeted depletion of secretory rhoptry protein ROP2 in Toxoplasma gondii
    • Nakaar V., Ngo H.M., Aaronson E.P., Coppens I., Stedman T.T., and Joiner K.A. Pleiotropic effect due to targeted depletion of secretory rhoptry protein ROP2 in Toxoplasma gondii. Journal of Cell Science 116 (2003) 2311-2320
    • (2003) Journal of Cell Science , vol.116 , pp. 2311-2320
    • Nakaar, V.1    Ngo, H.M.2    Aaronson, E.P.3    Coppens, I.4    Stedman, T.T.5    Joiner, K.A.6
  • 32
    • 0032146449 scopus 로고    scopus 로고
    • Immunization with E. coli produced recombinant T. gondii SAG1 with alum as adjuvant protect mice against lethal infection with Toxoplasma gondii
    • Petersen E., Nielsen H.V., Christiansen L., and Spenter J. Immunization with E. coli produced recombinant T. gondii SAG1 with alum as adjuvant protect mice against lethal infection with Toxoplasma gondii. Vaccine 16 (1998) 1283-1289
    • (1998) Vaccine , vol.16 , pp. 1283-1289
    • Petersen, E.1    Nielsen, H.V.2    Christiansen, L.3    Spenter, J.4
  • 33
    • 56149118583 scopus 로고    scopus 로고
    • New insights in toxoplasmosis immunology during pregnancy. Perspective for vaccine prevention
    • Pfaff A.W., and Candolfi E. New insights in toxoplasmosis immunology during pregnancy. Perspective for vaccine prevention. Parasitologia 50 (2008) 55-58
    • (2008) Parasitologia , vol.50 , pp. 55-58
    • Pfaff, A.W.1    Candolfi, E.2
  • 34
    • 0026076742 scopus 로고
    • Human T cell clone identifies a potentially protective 54-kDa protein antigen of Toxoplasma gondii cloned and expressed in Escherichia coli
    • Saavedra R., De Meuter F., Decourt J.L., and Herion P. Human T cell clone identifies a potentially protective 54-kDa protein antigen of Toxoplasma gondii cloned and expressed in Escherichia coli. The Journal of Immunology 147 (1991) 1975-1982
    • (1991) The Journal of Immunology , vol.147 , pp. 1975-1982
    • Saavedra, R.1    De Meuter, F.2    Decourt, J.L.3    Herion, P.4
  • 38
    • 0033955713 scopus 로고    scopus 로고
    • B cells are essential for vaccination-induced resistance to virulent Toxoplasma gondii
    • Sayles P.C., Gibson G.W., and Johnson L.L. B cells are essential for vaccination-induced resistance to virulent Toxoplasma gondii. Infection and Immunity 68 (2000) 1026-1033
    • (2000) Infection and Immunity , vol.68 , pp. 1026-1033
    • Sayles, P.C.1    Gibson, G.W.2    Johnson, L.L.3
  • 40
    • 0033082686 scopus 로고    scopus 로고
    • Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors
    • Sheffield P., Garrard S., and Derewenda Z. Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors. Protein Expression and Purification 15 (1999) 34-39
    • (1999) Protein Expression and Purification , vol.15 , pp. 34-39
    • Sheffield, P.1    Garrard, S.2    Derewenda, Z.3
  • 42
    • 0035833263 scopus 로고    scopus 로고
    • The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane
    • Sinai A.P., and Joiner K.A. The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane. The Journal of Cell Biology 154 (2001) 95-108
    • (2001) The Journal of Cell Biology , vol.154 , pp. 95-108
    • Sinai, A.P.1    Joiner, K.A.2
  • 43
    • 0027508691 scopus 로고
    • Serodiagnosis of toxoplasmosis by using a recombinant form of the 54-kilodalton rhoptry antigen expressed in Escherichia coli
    • Van Gelder P., Bosman F., De Meuter F., Van Heuverswyn H., and Herion P. Serodiagnosis of toxoplasmosis by using a recombinant form of the 54-kilodalton rhoptry antigen expressed in Escherichia coli. Journal of Clinical Microbiology 31 (1993) 9-15
    • (1993) Journal of Clinical Microbiology , vol.31 , pp. 9-15
    • Van Gelder, P.1    Bosman, F.2    De Meuter, F.3    Van Heuverswyn, H.4    Herion, P.5
  • 44
    • 0033961350 scopus 로고    scopus 로고
    • DNA vaccination with genes encoding Toxoplasma gondii antigens GRA1, GRA7, and ROP2 induces partially protective immunity against lethal challenge in mice
    • Vercammen M., Scorza T., Huygen K., De Braekeleer J., Diet R., Jacobs D., Saman E., and Verschueren H. DNA vaccination with genes encoding Toxoplasma gondii antigens GRA1, GRA7, and ROP2 induces partially protective immunity against lethal challenge in mice. Infection and Immunity 68 (2000) 38-45
    • (2000) Infection and Immunity , vol.68 , pp. 38-45
    • Vercammen, M.1    Scorza, T.2    Huygen, K.3    De Braekeleer, J.4    Diet, R.5    Jacobs, D.6    Saman, E.7    Verschueren, H.8
  • 45
    • 53049100142 scopus 로고    scopus 로고
    • Evaluation of the immune response elicited by multi-antigenic DNA vaccine expressing SAG1, ROP2 and GRA2 against Toxoplasma gondii
    • Xue M., He S., Cui Y., Yao Y., and Wang H. Evaluation of the immune response elicited by multi-antigenic DNA vaccine expressing SAG1, ROP2 and GRA2 against Toxoplasma gondii. Parasitology International 57 (2008) 424-429
    • (2008) Parasitology International , vol.57 , pp. 424-429
    • Xue, M.1    He, S.2    Cui, Y.3    Yao, Y.4    Wang, H.5
  • 46
    • 44249119349 scopus 로고    scopus 로고
    • Comparison of cholera toxin A2/B and murine interleukin-12 as adjuvants of Toxoplasma multi-antigenic SAG1-ROP2 DNA vaccine
    • Xue M., He S., Zhang J., Cui Y., Yao Y., and Wang H. Comparison of cholera toxin A2/B and murine interleukin-12 as adjuvants of Toxoplasma multi-antigenic SAG1-ROP2 DNA vaccine. Experimental Parasitology 119 (2008) 352-357
    • (2008) Experimental Parasitology , vol.119 , pp. 352-357
    • Xue, M.1    He, S.2    Zhang, J.3    Cui, Y.4    Yao, Y.5    Wang, H.6
  • 47
    • 0842308891 scopus 로고    scopus 로고
    • Protective immunity against Toxoplasma gondii in mice induced by a chimeric protein rSAG1/2
    • Yang C.D., Chang G.N., and Chao D. Protective immunity against Toxoplasma gondii in mice induced by a chimeric protein rSAG1/2. Parasitology Research 92 (2004) 58-64
    • (2004) Parasitology Research , vol.92 , pp. 58-64
    • Yang, C.D.1    Chang, G.N.2    Chao, D.3
  • 48
    • 34250849288 scopus 로고    scopus 로고
    • Evaluation of the immune response induced by multiantigenic DNA vaccine encoding SAG1 and ROP2 of Toxoplasma gondii and the adjuvant properties of murine interleukin-12 plasmid in BALB/c mice
    • Zhang J., He S., Jiang H., Yang T., Cong H., Zhou H., Zhang J., Gu Q., Li Y., and Zhao Q. Evaluation of the immune response induced by multiantigenic DNA vaccine encoding SAG1 and ROP2 of Toxoplasma gondii and the adjuvant properties of murine interleukin-12 plasmid in BALB/c mice. Parasitology Research 101 (2007) 331-338
    • (2007) Parasitology Research , vol.101 , pp. 331-338
    • Zhang, J.1    He, S.2    Jiang, H.3    Yang, T.4    Cong, H.5    Zhou, H.6    Zhang, J.7    Gu, Q.8    Li, Y.9    Zhao, Q.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.