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Volumn 33, Issue 2, 2011, Pages 81-94

Vaccination of mice with chitosan nanogel-associated recombinant NcPDI against challenge infection with Neospora caninum tachyzoites

Author keywords

Nanogels; Neospora caninum; Protein disulfide isomerase; vaccination

Indexed keywords

ALGINIC ACID; CHITOSAN; CYTOKINE; MANNOSE; MESSENGER RNA; NANOPARTICLE; PROTEIN DISULFIDE ISOMERASE;

EID: 78651462891     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2010.01255.x     Document Type: Article
Times cited : (52)

References (52)
  • 1
    • 0021341909 scopus 로고
    • Unidentified cyst-forming sporozoon causing encephalomyelitis and myositis in dogs
    • Bjerkas I, Mohn SF & Presthus J. Unidentified cyst-forming sporozoon causing encephalomyelitis and myositis in dogs. Z Parasitenkd 1984; 70: 271-274.
    • (1984) Z Parasitenkd , vol.70 , pp. 271-274
    • Bjerkas, I.1    Mohn, S.F.2    Presthus, J.3
  • 2
    • 0024289279 scopus 로고
    • Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission
    • Dubey JP, Hattel AL, Lindsay DS & Topper MJ. Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission. J Am Vet Med Assoc 1988; 193: 1259-1263.
    • (1988) J Am Vet Med Assoc , vol.193 , pp. 1259-1263
    • Dubey, J.P.1    Hattel, A.L.2    Lindsay, D.S.3    Topper, M.J.4
  • 3
    • 33747074886 scopus 로고    scopus 로고
    • Cellular and immunological basis of the host-parasite relationship during infection with Neospora caninum
    • Hemphill A, Vonlaufen N & Naguleswaran A. Cellular and immunological basis of the host-parasite relationship during infection with Neospora caninum. Parasitology 2006; 133: 261-278.
    • (2006) Parasitology , vol.133 , pp. 261-278
    • Hemphill, A.1    Vonlaufen, N.2    Naguleswaran, A.3
  • 4
    • 0030566651 scopus 로고    scopus 로고
    • A review of Neospora caninum and neosporosis
    • Dubey JP & Lindsay DS. A review of Neospora caninum and neosporosis. Vet Parasitol 1996; 67: 1-59.
    • (1996) Vet Parasitol , vol.67 , pp. 1-59
    • Dubey, J.P.1    Lindsay, D.S.2
  • 5
    • 0033042875 scopus 로고    scopus 로고
    • The host-parasite relationship in neosporosis
    • Hemphill A. The host-parasite relationship in neosporosis. Adv Parasitol 1999; 43: 47-104.
    • (1999) Adv Parasitol , vol.43 , pp. 47-104
    • Hemphill, A.1
  • 6
    • 34248210832 scopus 로고    scopus 로고
    • Epidemiology and control of neosporosis and Neospora caninum
    • Dubey JP, Schares G & Ortega-Mora LM. Epidemiology and control of neosporosis and Neospora caninum. Clin Microbiol Rev 2007; 20: 323-367.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 323-367
    • Dubey, J.P.1    Schares, G.2    Ortega-Mora, L.M.3
  • 9
    • 67650499884 scopus 로고    scopus 로고
    • Neospora caninum- how close are we to development of an efficacious vaccine that prevents abortion in cattle?
    • Reichel MP & Ellis JT. Neospora caninum- how close are we to development of an efficacious vaccine that prevents abortion in cattle? Int J Parasitol 2009; 39: 1173-1187.
    • (2009) Int J Parasitol , vol.39 , pp. 1173-1187
    • Reichel, M.P.1    Ellis, J.T.2
  • 10
    • 33847760357 scopus 로고    scopus 로고
    • Immunization of cattle with live tachyzoites of Neospora caninum confers protection against fetal death
    • Williams DJ, Guy CS, Smith RF, et al. Immunization of cattle with live tachyzoites of Neospora caninum confers protection against fetal death. Infect Immun 2007; 75: 1343-1348.
    • (2007) Infect Immun , vol.75 , pp. 1343-1348
    • Williams, D.J.1    Guy, C.S.2    Smith, R.F.3
  • 11
    • 55049087149 scopus 로고    scopus 로고
    • Evaluation of recombinant proteins of Neospora caninum as vaccine candidates (in a mouse model)
    • Ellis J, Miller C, Quinn H, Ryce C & Reichel MP. Evaluation of recombinant proteins of Neospora caninum as vaccine candidates (in a mouse model). Vaccine 2008; 26: 5989-5996.
    • (2008) Vaccine , vol.26 , pp. 5989-5996
    • Ellis, J.1    Miller, C.2    Quinn, H.3    Ryce, C.4    Reichel, M.P.5
  • 12
    • 33645093214 scopus 로고    scopus 로고
    • Protecting babies: vaccine strategies to prevent foetopathy in Neospora caninum-infected cattle
    • Williams DJ & Trees AJ. Protecting babies: vaccine strategies to prevent foetopathy in Neospora caninum-infected cattle. Parasite Immunol 2006; 28: 61-67.
    • (2006) Parasite Immunol , vol.28 , pp. 61-67
    • Williams, D.J.1    Trees, A.J.2
  • 13
    • 33846811391 scopus 로고    scopus 로고
    • Vaccination as a control strategy against the coccidial parasites Eimeria, Toxoplasma and Neospora
    • Innes EA & Vermeulen AN. Vaccination as a control strategy against the coccidial parasites Eimeria, Toxoplasma and Neospora. Parasitology 2006; 133: S145-S168.
    • (2006) Parasitology , vol.133
    • Innes, E.A.1    Vermeulen, A.N.2
  • 14
    • 5444251694 scopus 로고    scopus 로고
    • Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions
    • Romero JJ, Perez E & Frankena K. Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions. Vet Parasitol 2004; 123: 149-159.
    • (2004) Vet Parasitol , vol.123 , pp. 149-159
    • Romero, J.J.1    Perez, E.2    Frankena, K.3
  • 15
    • 26944476272 scopus 로고    scopus 로고
    • Neospora caninum protein disulfide isomerase is involved in tachyzoite-host cell interaction
    • Naguleswaran A, Alaeddine F, Guionaud C, et al. Neospora caninum protein disulfide isomerase is involved in tachyzoite-host cell interaction. Int J Parasitol 2005; 35: 1459-1472.
    • (2005) Int J Parasitol , vol.35 , pp. 1459-1472
    • Naguleswaran, A.1    Alaeddine, F.2    Guionaud, C.3
  • 16
    • 33846098250 scopus 로고    scopus 로고
    • Structure-activity relationships from in vitro efficacies of the thiazolide series against the intracellular apicomplexan protozoan Neospora caninum
    • Esposito M, Müller N & Hemphill A. Structure-activity relationships from in vitro efficacies of the thiazolide series against the intracellular apicomplexan protozoan Neospora caninum. Int J Parasitol 2007; 37: 183-190.
    • (2007) Int J Parasitol , vol.37 , pp. 183-190
    • Esposito, M.1    Müller, N.2    Hemphill, A.3
  • 17
    • 34447283736 scopus 로고    scopus 로고
    • Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs
    • Esposito M, Moores S, Naguleswaran A, Müller J & Hemphill A. Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs. Int J Parasitol 2007; 37: 1143-1152.
    • (2007) Int J Parasitol , vol.37 , pp. 1143-1152
    • Esposito, M.1    Moores, S.2    Naguleswaran, A.3    Müller, J.4    Hemphill, A.5
  • 18
    • 37349023592 scopus 로고    scopus 로고
    • Neospora caninum: functional inhibition of protein disulfide isomerase by the broad-spectrum anti-parasitic drug nitazoxanide and other thiazolides
    • Müller J, Naguleswaran A, Müller N & Hemphill A. Neospora caninum: functional inhibition of protein disulfide isomerase by the broad-spectrum anti-parasitic drug nitazoxanide and other thiazolides. Exp Parasitol 2008; 118: 80-88.
    • (2008) Exp Parasitol , vol.118 , pp. 80-88
    • Müller, J.1    Naguleswaran, A.2    Müller, N.3    Hemphill, A.4
  • 19
    • 77949653962 scopus 로고    scopus 로고
    • Intraperitoneal and intra-nasal vaccination of mice with three distinct recombinant Neospora caninum antigens results in differential effects with regard to protection against experimental challenge with Neospora caninum tachyzoites
    • Debache K, Guionaud C, Alaeddine F & Hemphill A. Intraperitoneal and intra-nasal vaccination of mice with three distinct recombinant Neospora caninum antigens results in differential effects with regard to protection against experimental challenge with Neospora caninum tachyzoites. Parasitology 2009; 137: 229-240.
    • (2009) Parasitology , vol.137 , pp. 229-240
    • Debache, K.1    Guionaud, C.2    Alaeddine, F.3    Hemphill, A.4
  • 20
    • 34248584919 scopus 로고    scopus 로고
    • Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers
    • Borges O, Borchard G, de Sousa A, Junginger HE & Cordeiro-da-Silva A. Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers. Int J Pharm 2007; 337: 254-264.
    • (2007) Int J Pharm , vol.337 , pp. 254-264
    • Borges, O.1    Borchard, G.2    de Sousa, A.3    Junginger, H.E.4    Cordeiro-da-Silva, A.5
  • 21
    • 0023255903 scopus 로고
    • Effect of multiporous microspheres derived from chitin and partially deacetylated chitin on the activation of mouse peritoneal macrophages
    • Nishimura K, Nishimura S, Seo H, Nishi N, Tokura S & Azuma I. Effect of multiporous microspheres derived from chitin and partially deacetylated chitin on the activation of mouse peritoneal macrophages. Vaccine 1987; 5: 136-140.
    • (1987) Vaccine , vol.5 , pp. 136-140
    • Nishimura, K.1    Nishimura, S.2    Seo, H.3    Nishi, N.4    Tokura, S.5    Azuma, I.6
  • 22
    • 0030901437 scopus 로고    scopus 로고
    • Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice
    • Shibata Y, Foster LA, Metzger WJ & Myrvik QN. Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice. Infect Immun 1997; 65: 1734-1741.
    • (1997) Infect Immun , vol.65 , pp. 1734-1741
    • Shibata, Y.1    Foster, L.A.2    Metzger, W.J.3    Myrvik, Q.N.4
  • 23
    • 24044543562 scopus 로고    scopus 로고
    • Differential levels of dendritic cell maturation on different biomaterials used in combination products
    • Babensee JE & Paranjpe A. Differential levels of dendritic cell maturation on different biomaterials used in combination products. J Biomed Mater Res A 2005; 74: 503-510.
    • (2005) J Biomed Mater Res A , vol.74 , pp. 503-510
    • Babensee, J.E.1    Paranjpe, A.2
  • 24
    • 0037654710 scopus 로고    scopus 로고
    • Microparticles as vaccine adjuvants and delivery systems
    • O'Hagan DT & Singh M. Microparticles as vaccine adjuvants and delivery systems. Expert Rev Vaccines 2003; 2: 269-283.
    • (2003) Expert Rev Vaccines , vol.2 , pp. 269-283
    • O'Hagan, D.T.1    Singh, M.2
  • 25
    • 33745192606 scopus 로고    scopus 로고
    • A novel chitosan CpG nanoparticle regulates cellular and humoral immunity of mice
    • Wu KY, Wu M, Fu ML, et al. A novel chitosan CpG nanoparticle regulates cellular and humoral immunity of mice. Biomed Environ Sci 2006; 19: 87-95.
    • (2006) Biomed Environ Sci , vol.19 , pp. 87-95
    • Wu, K.Y.1    Wu, M.2    Fu, M.L.3
  • 27
    • 36549067721 scopus 로고    scopus 로고
    • Chitosan solution enhances the immunoadjuvant properties of GM-CSF
    • Zaharoff DA, Rogers CJ, Hance KW, Schlom J & Greiner JW. Chitosan solution enhances the immunoadjuvant properties of GM-CSF. Vaccine 2007; 25: 8673-8686.
    • (2007) Vaccine , vol.25 , pp. 8673-8686
    • Zaharoff, D.A.1    Rogers, C.J.2    Hance, K.W.3    Schlom, J.4    Greiner, J.W.5
  • 28
    • 0036716434 scopus 로고    scopus 로고
    • Enhancement of protective efficacy following intranasal immunization with vaccine plus a nontoxic LTK63 mutant delivered with nanoparticles
    • Baudner BC, Balland O, Giuliani MM, et al. Enhancement of protective efficacy following intranasal immunization with vaccine plus a nontoxic LTK63 mutant delivered with nanoparticles. Infect Immun 2002; 70: 4785-4790.
    • (2002) Infect Immun , vol.70 , pp. 4785-4790
    • Baudner, B.C.1    Balland, O.2    Giuliani, M.M.3
  • 29
    • 0037471396 scopus 로고    scopus 로고
    • Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice
    • van der Lubben IM, Kersten G, Fretz MM, Beuvery C, Coos Verhoef J & Junginger HE. Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice. Vaccine 2003; 21: 1400-1408.
    • (2003) Vaccine , vol.21 , pp. 1400-1408
    • van der Lubben, I.M.1    Kersten, G.2    Fretz, M.M.3    Beuvery, C.4    Coos, V.J.5    Junginger, H.E.6
  • 30
    • 16244384193 scopus 로고    scopus 로고
    • Development of a single dose tetanus toxoid formulation based on polymeric microspheres: a comparative study of poly(D,L-lactic-co-glycolic acid) versus chitosan microspheres
    • Jaganathan KS, Rao YU, Singh P, et al. Development of a single dose tetanus toxoid formulation based on polymeric microspheres: a comparative study of poly(D, L-lactic-co-glycolic acid) versus chitosan microspheres. Int J Pharm 2005; 294: 23-32.
    • (2005) Int J Pharm , vol.294 , pp. 23-32
    • Jaganathan, K.S.1    Rao, Y.U.2    Singh, P.3
  • 31
    • 0346094226 scopus 로고    scopus 로고
    • Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice
    • Vila A, Sanchez A, Janes K, et al. Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice. Eur J Pharm Biopharm 2004; 57: 123-131.
    • (2004) Eur J Pharm Biopharm , vol.57 , pp. 123-131
    • Vila, A.1    Sanchez, A.2    Janes, K.3
  • 32
    • 33644789168 scopus 로고    scopus 로고
    • Protective immune responses to meningococcal C conjugate vaccine after intranasal immunization of mice with the LTK63 mutant plus chitosan or trimethyl chitosan chloride as novel delivery platform
    • Baudner BC, Verhoef JC, Giuliani MM, et al. Protective immune responses to meningococcal C conjugate vaccine after intranasal immunization of mice with the LTK63 mutant plus chitosan or trimethyl chitosan chloride as novel delivery platform. J Drug Target 2005; 13: 489-498.
    • (2005) J Drug Target , vol.13 , pp. 489-498
    • Baudner, B.C.1    Verhoef, J.C.2    Giuliani, M.M.3
  • 33
    • 0033801493 scopus 로고    scopus 로고
    • Carbohydrate biopolymers enhance antibody responses to mucosally delivered vaccine antigens
    • Bacon A, Makin J, Sizer PJ, et al. Carbohydrate biopolymers enhance antibody responses to mucosally delivered vaccine antigens. Infect Immun 2000; 68: 5764-5770.
    • (2000) Infect Immun , vol.68 , pp. 5764-5770
    • Bacon, A.1    Makin, J.2    Sizer, P.J.3
  • 34
    • 22244486625 scopus 로고    scopus 로고
    • Effective nasal influenza vaccine delivery using chitosan
    • Read RC, Naylor SC, Potter CW, et al. Effective nasal influenza vaccine delivery using chitosan. Vaccine 2005; 23: 4367-4374.
    • (2005) Vaccine , vol.23 , pp. 4367-4374
    • Read, R.C.1    Naylor, S.C.2    Potter, C.W.3
  • 35
    • 33646139149 scopus 로고    scopus 로고
    • Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally
    • Jaganathan KS & Vyas SP. Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally. Vaccine 2006; 24: 4201-4211.
    • (2006) Vaccine , vol.24 , pp. 4201-4211
    • Jaganathan, K.S.1    Vyas, S.P.2
  • 36
    • 21844435468 scopus 로고    scopus 로고
    • Preparation of coated nanoparticles for a new mucosal vaccine delivery system
    • Borges O, Borchard G, Verhoef JC, de Sousa A & Junginfger HE. Preparation of coated nanoparticles for a new mucosal vaccine delivery system. Int J Pharm 2005; 299: 155-166.
    • (2005) Int J Pharm , vol.299 , pp. 155-166
    • Borges, O.1    Borchard, G.2    Verhoef, J.C.3    de, S.A.4    Junginfger, H.E.5
  • 37
    • 33748131292 scopus 로고    scopus 로고
    • Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination
    • Borges O, Cordeiro-da-Silva A, Romeijn SG, et al. Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination. J Control Release 2006; 114: 348-358.
    • (2006) J Control Release , vol.114 , pp. 348-358
    • Borges, O.1    Cordeiro-da-Silva, A.2    Romeijn, S.G.3
  • 38
    • 35748974510 scopus 로고    scopus 로고
    • Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles
    • Borges O, Tavares J, de Sousa A, Borchard G, Junginger HE & Cordeiro-da-Silva A. Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles. Eur J Pharm Sci 2007; 32: 278-290.
    • (2007) Eur J Pharm Sci , vol.32 , pp. 278-290
    • Borges, O.1    Tavares, J.2    de Sousa, A.3    Borchard, G.4    Junginger, H.E.5    Cordeiro-da-Silva, A.6
  • 39
    • 0030023672 scopus 로고    scopus 로고
    • Adhesion and invasion of bovine endothelial cells by Neospora caninum
    • Hemphill A, Gottstein B & Kaufmann H. Adhesion and invasion of bovine endothelial cells by Neospora caninum. Parasitology 1996; 112: 183-197.
    • (1996) Parasitology , vol.112 , pp. 183-197
    • Hemphill, A.1    Gottstein, B.2    Kaufmann, H.3
  • 40
    • 51249107767 scopus 로고    scopus 로고
    • Vaccination of mice with recombinant NcROP2 antigen reduces mortality and cerebral infection in mice infected with Neospora caninum tachyzoites
    • Debache K, Guionaud C, Alaeddine F, Mevissen M & Hemphill A. Vaccination of mice with recombinant NcROP2 antigen reduces mortality and cerebral infection in mice infected with Neospora caninum tachyzoites. Int J Parasitol 2008; 38: 1455-1463.
    • (2008) Int J Parasitol , vol.38 , pp. 1455-1463
    • Debache, K.1    Guionaud, C.2    Alaeddine, F.3    Mevissen, M.4    Hemphill, A.5
  • 41
    • 0037396665 scopus 로고    scopus 로고
    • Vaccination of mice against experimental Neospora caninum infection using NcSAG1- and NcSRS2-based recombinant antigens and DNA vaccines
    • Cannas A, Naguleswaran A, Müller N, Eperon S, Gottstein B & Hemphill A. Vaccination of mice against experimental Neospora caninum infection using NcSAG1- and NcSRS2-based recombinant antigens and DNA vaccines. Parasitology 2003; 126: 303-312.
    • (2003) Parasitology , vol.126 , pp. 303-312
    • Cannas, A.1    Naguleswaran, A.2    Müller, N.3    Eperon, S.4    Gottstein, B.5    Hemphill, A.6
  • 42
    • 0037325687 scopus 로고    scopus 로고
    • Reduced cerebral infection of Neospora caninum-infected mice after vaccination with recombinant microneme protein NcMIC3 and ribi adjuvant
    • Cannas A, Naguleswaran A, Müller N, Gottstein B & Hemphill A. Reduced cerebral infection of Neospora caninum-infected mice after vaccination with recombinant microneme protein NcMIC3 and ribi adjuvant. J Parasitol 2003; 89: 44-50.
    • (2003) J Parasitol , vol.89 , pp. 44-50
    • Cannas, A.1    Naguleswaran, A.2    Müller, N.3    Gottstein, B.4    Hemphill, A.5
  • 43
    • 22244476152 scopus 로고    scopus 로고
    • Reduced infection and protection from clinical signs of cerebral neosporosis in C57BL/6 mice vaccinated with recombinant microneme antigen NcMIC1
    • Alaeddine F, Keller N, Leepin A & Hemphill A. Reduced infection and protection from clinical signs of cerebral neosporosis in C57BL/6 mice vaccinated with recombinant microneme antigen NcMIC1. J Parasitol 2005; 91: 657-665.
    • (2005) J Parasitol , vol.91 , pp. 657-665
    • Alaeddine, F.1    Keller, N.2    Leepin, A.3    Hemphill, A.4
  • 44
    • 68049137627 scopus 로고    scopus 로고
    • Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites
    • Debache K, Alaeddine F, Guionaud C, et al. Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites. Int J Parasitol 2009; 39: 1373-1384.
    • (2009) Int J Parasitol , vol.39 , pp. 1373-1384
    • Debache, K.1    Alaeddine, F.2    Guionaud, C.3
  • 45
    • 36749046331 scopus 로고    scopus 로고
    • Vaccination with microneme protein NcMIC4 increases mortality in mice inoculated with Neospora caninum
    • Srinivasan S, Müller J, Suana A & Hemphill A. Vaccination with microneme protein NcMIC4 increases mortality in mice inoculated with Neospora caninum. J Parasitol 2007; 93: 1046-1055.
    • (2007) J Parasitol , vol.93 , pp. 1046-1055
    • Srinivasan, S.1    Müller, J.2    Suana, A.3    Hemphill, A.4
  • 46
    • 0036136354 scopus 로고    scopus 로고
    • Application of real-time fluorescent PCR for quantitative assessment of Neospora caninum infections in organotypic slice cultures of rat central nervous system tissue
    • Müller N, Vonlaufen N, Gianinazzi C, Leib SL & Hemphill A. Application of real-time fluorescent PCR for quantitative assessment of Neospora caninum infections in organotypic slice cultures of rat central nervous system tissue. J Clin Microbiol 2002; 40: 252-255.
    • (2002) J Clin Microbiol , vol.40 , pp. 252-255
    • Müller, N.1    Vonlaufen, N.2    Gianinazzi, C.3    Leib, S.L.4    Hemphill, A.5
  • 47
    • 0033119065 scopus 로고    scopus 로고
    • Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR
    • Overbergh L, Valckx D, Waer M & Mathieu C. Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR. Cytokine 1999; 11: 305-312.
    • (1999) Cytokine , vol.11 , pp. 305-312
    • Overbergh, L.1    Valckx, D.2    Waer, M.3    Mathieu, C.4
  • 48
    • 78651456072 scopus 로고    scopus 로고
    • R Development Core Team., R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0. Available from:.
    • R Development Core Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0. 2009; Available from:.
    • (2009)
  • 49
    • 59649098841 scopus 로고    scopus 로고
    • Effects of a transferring antibody against Neospora caninum infection in a murine model
    • Nishikawa Y, Zhang H, Huang P, Zhang G & Xuan X. Effects of a transferring antibody against Neospora caninum infection in a murine model. Vet Parasitol 2009; 160: 60-65.
    • (2009) Vet Parasitol , vol.160 , pp. 60-65
    • Nishikawa, Y.1    Zhang, H.2    Huang, P.3    Zhang, G.4    Xuan, X.5
  • 50
    • 33846881091 scopus 로고    scopus 로고
    • Natural killer cells act as early responders in an experimental infection with Neospora caninum in calves
    • Klevar S, Kulberg S, Boysen P, et al. Natural killer cells act as early responders in an experimental infection with Neospora caninum in calves. Int J Parasitol 2007; 37: 329-339.
    • (2007) Int J Parasitol , vol.37 , pp. 329-339
    • Klevar, S.1    Kulberg, S.2    Boysen, P.3
  • 51
    • 34548678210 scopus 로고    scopus 로고
    • Prevention of vertical transmission of Neospora caninum in C57BL/6 mice vaccinated with Brucella abortus strain RB51 expressing N. caninum protective antigens
    • Ramamoorthy S, Sanakkayala N, Vemulapalli R, et al. Prevention of vertical transmission of Neospora caninum in C57BL/6 mice vaccinated with Brucella abortus strain RB51 expressing N. caninum protective antigens. Int J Parasitol 2007; 37: 1531-1538.
    • (2007) Int J Parasitol , vol.37 , pp. 1531-1538
    • Ramamoorthy, S.1    Sanakkayala, N.2    Vemulapalli, R.3
  • 52
    • 26944480044 scopus 로고    scopus 로고
    • Immunization with native surface protein NcSRS2 induces a Th2 immune response and reduces congenital Neospora caninum transmission in mice
    • Haldorson GJ, Mathison BA, Wenberg K, et al. Immunization with native surface protein NcSRS2 induces a Th2 immune response and reduces congenital Neospora caninum transmission in mice. Int J Parasitol 2005; 35: 1407-1415.
    • (2005) Int J Parasitol , vol.35 , pp. 1407-1415
    • Haldorson, G.J.1    Mathison, B.A.2    Wenberg, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.