Immunisation of mice against neosporosis with recombinant NcSRS2 iscoms

Veterinary Parasitology

Volumn 129, Issue 1-2, 2005, Pages 25-34

  Pinitkiatisakul, Sunan ^a   Mattsson, Jens G ^a   Wikman, Maria ^b   Friedman, Mikaela ^b   Bengtsson, Karin Lövgren ^c   Ståhl, Stefan ^b   Lundén, Anna ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b ALBANOVA UNIVERSITY CENTER   (Sweden)

^c Isconova AB   (Sweden)

Author keywords

Antibody response; Competetive PCR; Iscom; NcSRS2; Neospora caninum; Recombinant immunogen; Subunit vaccine

Indexed keywords

BIOTIN; ISCOM; MEMBRANE ANTIGEN; PROTOZOAL DNA; RECOMBINANT NCSRS2 IMMUNE STIMULATING COMPLEX; RECOMBINANT PROTEIN; STREPTAVIDIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ANTIBODY TITER; ANTIGEN ANTIBODY REACTION; ARTICLE; BRAIN; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; IMMUNITY; IMMUNIZATION; INOCULATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTOZOAL INFECTION; VACCINATION;

BOS TAURUS; COCCIDIA; ESCHERICHIA COLI; NEOSPORA CANINUM; PROTOZOA;

EID: 16244380770     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2004.12.004     Document Type: Article

References (46)

1. M.L. Anderson, P.C. Blanchard, B.C. Barr, J.P. Dubey, R.L. Hoffman, and P.A. Conrad Neospora-like protozoan infection as a major cause of abortion in California dairy cattle J. Am. Vet. Med. Assoc. 198 1991 241 244
2. F.G. Araujo, and B. Morein Immunization with Trypanosoma cruzi epimastigote antigens incorporated into iscoms protects against lethal challenge in mice Infect. Immun. 59 1991 2909 2914
3. P.C. Augustine, M.C. Jenkins, and J.P. Dubey Effect of polyclonal antisera developed against dense granule-associated Neospora caninum proteins on cell invasion and development in vitro by N. caninum tachyzoites Parasitology 119 Pt 5 1999 441 445
4. B.C. Barr, M.L. Anderson, J.P. Dubey, and P.A. Conrad Neospora-like protozoal infections associated with bovine abortions Vet. Pathol. 28 1991 110 116
5. T.V. Baszler, M.T. Long, T.F. McElwain, and B.A. Mathison Interferon-gamma and interleukin-12 mediate protection to acute Neospora caninum infection in BALB/c mice Int. J. Parasitol. 29 1999 1635 1646
6. R. Biemans, D. Gregoire, M. Haumont, A. Bosseloir, L. Garcia, A. Jacquet, C. Dubeaux, and A. Bollen The conformation of purified Toxoplasma gondii SAG1 antigen, secreted from engineered Pichia pastoris, is adequate for serorecognition and cell proliferation J. Biotechnol. 66 1998 137 146
7. I. Bjerkås, S.F. Mohn, and J. Presthus Unidentified cyst-forming sporozoon causing encephalomyelitis and myositis in dogs Z. Parasitenkd. 70 1984 271 274
8. C. Björkman, and A. Lundén Application of iscom antigen preparations in ELISAs for diagnosis of Neospora and Toxoplasma infections Int. J. Parasitol. 28 1998 187 193
9. A. Cannas, A. Naguleswaran, N. Müller, S. Eperon, B. Gottstein, and A. Hemphill Vaccination of mice against experimental Neospora caninum infection using NcSAG1- and NcSRS2-based recombinant antigens and DNA vaccines Parasitology 126 2003 303 312
10. J.P. Dubey Recent advances in Neospora and neosporosis Vet. Parasitol. 84 1999 349 367
11. J.P. Dubey Review of Neospora caninum and neosporosis in animals Korean J. Parasitol. 41 2003 1 16
12. J.P. Dubey, A.L. Hattel, D.S. Lindsay, M.J. Topper, and A. Uggla Newly recognized fatal protozoan disease of dogs J. Am. Vet. Med. Assoc. 192 1988 1269 1285
13. J.P. Dubey, A.L. Hattel, D.S. Lindsay, and M.J. Topper Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission J. Am. Vet. Med. Assoc. 193 1988 1259 1263
14. S. Eperon, K. Brönnimann, A. Hemphill, and B. Gottstein Susceptibility of B-cell deficient C57BL/6 (microMT) mice to Neospora caninum infection Parasite Immunol. 21 1999 225 236
15. N. Fuchs, S. Sonda, B. Gottstein, and A. Hemphill Differential expression of cell surface- and dense granule-associated Neospora caninum proteins in tachyzoites and bradyzoites J. Parasitol. 84 1998 753 758
16. D. Harning, J. Spenter, A. Metsis, J. Vuust, and E. Petersen Recombinant Toxoplasma gondii surface antigen 1 (P30) expressed in Escherichia coli is recognized by human Toxoplasma-specific immunoglobulin M (IgM) and IgG antibodies Clin. Diagn. Lab. Immunol. 3 1996 355 357
17. A. Hemphill Subcellular localization and functional characterization of Nc-p43, a major Neospora caninum tachyzoite surface protein Infect. Immun. 64 1996 4279 4287
18. A. Hemphill, R. Felleisen, B. Connolly, B. Gottstein, B. Hentrich, and N. Müller Characterization of a cDNA-clone encoding Nc-p43, a major Neospora caninum tachyzoite surface protein Parasitology 115 Pt 6 1997 581 590
19. D.K. Howe, A.C. Crawford, D. Lindsay, and L.D. Sibley The p29 and p35 immunodominant antigens of Neospora caninum tachyzoites are homologous to the family of surface antigens of Toxoplasma gondii Infect. Immun. 66 1998 5322 5328
20. E.A. Innes, S.E. Wright, S. Maley, A. Rae, A. Schock, E. Kirvar, P. Bartley, C. Hamilton, I.M. Carey, and D. Buxton Protection against vertical transmission in bovine neosporosis Int. J. Parasitol. 31 2001 1523 1534
21. E.A. Innes, A.G. Andrianarivo, C. Björkman, D.J. Williams, and P.A. Conrad Immune responses to Neospora caninum and prospects for vaccination Trends Parasitol. 18 2002 497 504
22. H. Kaufmann, M. Yamage, I. Roditi, D. Dobbelaere, J.P. Dubey, O.J. Holmdahl, A. Trees, and B. Gottstein Discrimination of Neospora caninum from Toxoplasma gondii and other apicomplexan parasites by hybridization and PCR Mol. Cell. Probes 10 1996 289 297
23. M. Kazanji, F. Laurent, and P. Pery Immune responses and protective effect in mice vaccinated orally with surface sporozoite protein of Eimeria falciformis in ISCOMs Vaccine 12 1994 798 804
24. I.A. Khan, J.D. Schwartzman, S. Fonseka, and L.H. Kasper Neospora caninum: role for immune cytokines in host immunity Exp. Parasitol. 85 1997 24 34
25. K. Kim, R. Bülow, J. Kampmeier, and J.C. Boothroyd Conformationally appropriate expression of the Toxoplasma antigen SAG1 (p30) in CHO cells Infect. Immun. 62 1994 203 209
26. S. Liddell, M.C. Jenkins, C.M. Collica, and J.P. Dubey Prevention of vertical transfer of Neospora caninum in BALB/c mice by vaccination J. Parasitol. 85 1999 1072 1075
27. S. Liddell, M.C. Jenkins, and J.P. Dubey A competitive PCR assay for quantitative detection of Neospora caninum Int. J. Parasitol. 29 1999 1583 1587
28. D.S. Lindsay, S.D. Lenz, R.A. Cole, J.P. Dubey, and B.L. Blagburn Mouse model for central nervous system Neospora caninum infections J. Parasitol. 81 1995 313 315
29. D.S. Lindsay, S.D. Lenz, B.L. Blagburn, and D.A. Brake Characterization of temperature-sensitive strains of Neospora caninum in mice J. Parasitol. 85 1995 64 67
30. M.T. Long, T.V. Baszler, and B.A. Mathison Comparison of intracerebral parasite load, lesion development, and systemic cytokines in mouse strains infected with Neospora caninum J. Parasitol. 84 1998 316 320
31. M.T. Long, and T.V. Baszler Neutralization of maternal IL-4 modulates congenital protozoal transmission: comparison of innate versus acquired immune responses J. Immunol. 164 2000 4768 4774
32. A. Lundén, K. Lövgren, A. Uggla, and F.G. Araujo Immune responses and resistance to Toxoplasma gondii in mice immunized with antigens of the parasite incorporated into immunostimulating complexes Infect. Immun. 61 1993 2639 2643
33. A. Lundén, S. Wright, J.E. Allen, and D. Buxton Immunisation of mice against neosporosis Int. J. Parasitol. 32 2002 867 876
34. B. Morein, B. Sundquist, S. Höglund, K. Dalsgaard, and A. Osterhaus Iscom, a novel structure for antigenic presentation of membrane proteins from enveloped viruses Nature 308 1984 457 460
35. B. Morein, and K.L. Bengtsson Immunomodulation by iscoms, immune stimulating complexes Methods 19 1999 94 102
36. Y. Nishikawa, X. Xuan, H. Nagasawa, I. Igarashi, K. Fujisaki, H. Otsuka, and T. Mikami Monoclonal antibody inhibition of Neospora caninum tachyzoite invasion into host cells Int. J. Parasitol. 30 2000 51 58
37. Y. Nishikawa, N. Inoue, X. Xuan, H. Nagasawa, I. Igarashi, K. Fujisaki, H. Otsuka, and T. Mikami Protective efficacy of vaccination by recombinant vaccinia virus against Neospora caninum infection Vaccine 19 2001 1381 1390
38. Y. Nishikawa, X. Xuan, H. Nagasawa, I. Igarashi, K. Fujisaki, H. Otsuka, and T. Mikami Prevention of vertical transmission of Neospora caninum in BALB/c mice by recombinant vaccinia virus carrying NcSRS2 gene Vaccine 19 2001 1710 1716
39. H.E. Quinn, J.T. Ellis, and N.C. Smith Neospora caninum: a cause of immune-mediated failure of pregnancy? Trends Parasitol. 18 2002 391 394
40. G. Schares, J.F. Dubremetz, J.P. Dubey, A. Bärwald, A. Loyens, and F.J. Conraths Neospora caninum: identification of 19-, 38-, and 40-kDa surface antigens and a 33-kDa dense granule antigen using monoclonal antibodies Exp. Parasitol. 92 1999 109 119
41. A. Sjölander, M. Hansson, K. Lövgren, B. Wåhlin, K. Berzins, and P. Perlmann Immunogenicity in rabbits and monkeys of influenza ISCOMs conjugated with repeated sequences of the Plasmodium falciparum antigen Pf155/RESA Parasite Immunol. 15 1993 355 359
42. S. Sonda, N. Fuchs, B. Connolly, P. Fernandez, B. Gottstein, and A. Hemphill The major 36 kDa Neospora caninum tachyzoite surface protein is closely related to the major Toxoplasma gondii surface antigen Mol. Biochem. Parasitol. 97 1998 97 108
43. A.J. Trees, H.C. Davison, E.A. Innes, and J.M. Wastling Towards evaluating the economic impact of bovine neosporosis Int. J. Parasitol. 29 1999 1195 1200
44. F. Velge-Roussel, T. Chardes, P. Mevelec, M. Brillard, J. Hoebeke, and D. Bout Epitopic analysis of the Toxoplasma gondii major surface antigen SAG1 Mol. Biochem. Parasitol. 66 1994 31 38
45. Wikman, M., Friedman, M., Pinitkiatisakul, S., Hemphill, A., Lövgren-Bengtsson, K., Lundén, A., Ståhl, S., 2005. Applying biotin-streptavidin binding for iscom association of recombinant immunogens. Biotechnol. Appl. Biochem., in press.
46. D.J. Williams, C.S. Guy, J.W. McGarry, F. Guy, L. Tasker, R.F. Smith, K. MacEachern, P.J. Cripps, D.F. Kelly, and A.J. Trees Neospora caninum-associated abortion in cattle: the time of experimentally-induced parasitaemia during gestation determines foetal survival Parasitology 121 Pt 4 2000 347 358