메뉴 건너뛰기




Volumn 38, Issue 12, 2008, Pages 1455-1463

Vaccination of mice with recombinant NcROP2 antigen reduces mortality and cerebral infection in mice infected with Neospora caninum tachyzoites

Author keywords

Cerebral infection; Host cell invasion; Neospora caninum; Neosporosis; ROP2; Vaccination

Indexed keywords

ANTISERUM; COMPLEMENTARY DNA; FREUND ADJUVANT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2A ANTIBODY; NCROP2 ANTIGEN; RECOMBINANT PROTEIN; SAPONIN; UNCLASSIFIED DRUG;

EID: 51249107767     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2008.04.001     Document Type: Article
Times cited : (64)

References (49)
  • 2
    • 22244476152 scopus 로고    scopus 로고
    • Reduced infection and protection from clinical signs of cerebral neosporosis in C57BL/6 mice vaccinated with recombinant microneme antigen NcMIC1
    • Alaeddine F., Keller N., Leepin A., and Hemphill A. Reduced infection and protection from clinical signs of cerebral neosporosis in C57BL/6 mice vaccinated with recombinant microneme antigen NcMIC1. J. Parasitol. 91 (2005) 657-665
    • (2005) J. Parasitol. , vol.91 , pp. 657-665
    • Alaeddine, F.1    Keller, N.2    Leepin, A.3    Hemphill, A.4
  • 3
    • 0034462220 scopus 로고    scopus 로고
    • Immunization of BALB/c mice with killed Neospora caninum tachyzoite antigen induces a type 2 immune response and exacerbates encephalitis and neurological disease
    • Baszler T.V., McElwain T.F., and Mathison B.A. Immunization of BALB/c mice with killed Neospora caninum tachyzoite antigen induces a type 2 immune response and exacerbates encephalitis and neurological disease. Clin. Diagn. Lab. Immunol. 7 (2000) 893-898
    • (2000) Clin. Diagn. Lab. Immunol. , vol.7 , pp. 893-898
    • Baszler, T.V.1    McElwain, T.F.2    Mathison, B.A.3
  • 5
    • 0037396665 scopus 로고    scopus 로고
    • Vaccination of mice against experimental N. caninum infection using NcSAG1- and NcSRS2-based recombinant antigens and DNA-vaccines
    • Cannas A., Naguleswaran A., Müller N., Gottstein B., Eperon S., and Hemphill A. Vaccination of mice against experimental N. caninum infection using NcSAG1- and NcSRS2-based recombinant antigens and DNA-vaccines. Parasitology 126 (2003) 303-312
    • (2003) Parasitology , vol.126 , pp. 303-312
    • Cannas, A.1    Naguleswaran, A.2    Müller, N.3    Gottstein, B.4    Eperon, S.5    Hemphill, A.6
  • 6
    • 0037325687 scopus 로고    scopus 로고
    • Reduced cerebral infection of Neospora caninum-infected mice after vaccination with recombinant microneme protein NcMIC3 and ribi adjuvant
    • Cannas A., Naguleswaran A., Muller N., Gottstein B., and Hemphill A. Reduced cerebral infection of Neospora caninum-infected mice after vaccination with recombinant microneme protein NcMIC3 and ribi adjuvant. J. Parasitol. 89 (2003) 44-50
    • (2003) J. Parasitol. , vol.89 , pp. 44-50
    • Cannas, A.1    Naguleswaran, A.2    Muller, N.3    Gottstein, B.4    Hemphill, A.5
  • 7
    • 0033386197 scopus 로고    scopus 로고
    • Cytokine, chemokine and chemokine receptor mRNA expression in different strains of normal mice: implications for establishment of a Th1/Th2 bias
    • Charles P.C., Weber K.S., Cipriani B., and Brosnan C.F. Cytokine, chemokine and chemokine receptor mRNA expression in different strains of normal mice: implications for establishment of a Th1/Th2 bias. J. Neuroimmunol. 100 (1999) 64-73
    • (1999) J. Neuroimmunol. , vol.100 , pp. 64-73
    • Charles, P.C.1    Weber, K.S.2    Cipriani, B.3    Brosnan, C.F.4
  • 8
    • 17844367149 scopus 로고    scopus 로고
    • Protective efficacy of vaccination with Neospora caninum multiple recombinant antigens against experimental Neospora caninum infection
    • Cho J.H., Chung W.S., Song K.J., Na B.K., Kang S.W., Song C.Y., and Kim T.S. Protective efficacy of vaccination with Neospora caninum multiple recombinant antigens against experimental Neospora caninum infection. Korean J. Parasitol. 43 (2005) 19-25
    • (2005) Korean J. Parasitol. , vol.43 , pp. 19-25
    • Cho, J.H.1    Chung, W.S.2    Song, K.J.3    Na, B.K.4    Kang, S.W.5    Song, C.Y.6    Kim, T.S.7
  • 9
    • 0032753956 scopus 로고    scopus 로고
    • Estimation of vertical and horizontal transmission parameters of Neospora caninum infections in dairy cattle
    • Davison H.C., Otter A., and Trees A.J. Estimation of vertical and horizontal transmission parameters of Neospora caninum infections in dairy cattle. Int. J. Parasitol. 29 (1999) 1683-1689
    • (1999) Int. J. Parasitol. , vol.29 , pp. 1683-1689
    • Davison, H.C.1    Otter, A.2    Trees, A.J.3
  • 10
    • 0032701392 scopus 로고    scopus 로고
    • Oral infection of calves with Neospora caninum oocysts from dogs: humoral and cellular immune responses
    • De Marez T., Liddell S., Dubey J.P., Jenkins M.C., and Gasbarre L. Oral infection of calves with Neospora caninum oocysts from dogs: humoral and cellular immune responses. Int. J. Parasitol. 29 (1999) 1647-1657
    • (1999) Int. J. Parasitol. , vol.29 , pp. 1647-1657
    • De Marez, T.1    Liddell, S.2    Dubey, J.P.3    Jenkins, M.C.4    Gasbarre, L.5
  • 11
    • 33947109437 scopus 로고    scopus 로고
    • Rhoptries are major players in Toxoplasma gondii invasion and host cell interaction
    • Dubremetz J.F. Rhoptries are major players in Toxoplasma gondii invasion and host cell interaction. Cell. Microbiol. 9 (2007) 841-848
    • (2007) Cell. Microbiol. , vol.9 , pp. 841-848
    • Dubremetz, J.F.1
  • 12
    • 0024289279 scopus 로고
    • Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission
    • Dubey J.P., Hattel A.L., Lindsay D.S., and Topper M.J. Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission. J. Am. Vet. Med. Assoc. 193 (1988) 1259-1263
    • (1988) J. Am. Vet. Med. Assoc. , vol.193 , pp. 1259-1263
    • Dubey, J.P.1    Hattel, A.L.2    Lindsay, D.S.3    Topper, M.J.4
  • 13
    • 34248210832 scopus 로고    scopus 로고
    • Epidemiology and control of neosporosis and Neospora caninum
    • Dubey J.P., Schares G., and Ortega L.M. Epidemiology and control of neosporosis and Neospora caninum. Clin. Microbiol. Rev. 20 (2007) 323-367
    • (2007) Clin. Microbiol. Rev. , vol.20 , pp. 323-367
    • Dubey, J.P.1    Schares, G.2    Ortega, L.M.3
  • 15
    • 0032923424 scopus 로고    scopus 로고
    • Susceptibility of B-cell deficient C57BL/6 (microMT) mice to Neospora caninum infection
    • Eperon S., Brönnimann K., Hemphill A., and Gottstein B. Susceptibility of B-cell deficient C57BL/6 (microMT) mice to Neospora caninum infection. Parasite Immunol. 21 (1999) 225-236
    • (1999) Parasite Immunol. , vol.21 , pp. 225-236
    • Eperon, S.1    Brönnimann, K.2    Hemphill, A.3    Gottstein, B.4
  • 17
    • 26944480044 scopus 로고    scopus 로고
    • Immunization with native surface protein NcSRS2 induces a Th2 immune response and reduces congenital Neospora caninum transmission in mice
    • Haldorson G.J., Mathison B.A., Wenberg K., Conrad P.A., Dubey J.P., Trees A.J., Yamane I., and Baszler T.V. Immunization with native surface protein NcSRS2 induces a Th2 immune response and reduces congenital Neospora caninum transmission in mice. Int. J. Parasitol. 35 (2005) 1407-1415
    • (2005) Int. J. Parasitol. , vol.35 , pp. 1407-1415
    • Haldorson, G.J.1    Mathison, B.A.2    Wenberg, K.3    Conrad, P.A.4    Dubey, J.P.5    Trees, A.J.6    Yamane, I.7    Baszler, T.V.8
  • 18
    • 32644484729 scopus 로고    scopus 로고
    • Neospora caninum: antibodies directed against tachyzoite surface protein NcSRS2 inhibit parasite attachment and invasion of placental trophoblasts in vitro
    • Haldorson G.J., Stanton J.B., Mathison B.A., Suarez C.E., and Baszler T.V. Neospora caninum: antibodies directed against tachyzoite surface protein NcSRS2 inhibit parasite attachment and invasion of placental trophoblasts in vitro. Exp. Parasitol. 112 (2006) 172-178
    • (2006) Exp. Parasitol. , vol.112 , pp. 172-178
    • Haldorson, G.J.1    Stanton, J.B.2    Mathison, B.A.3    Suarez, C.E.4    Baszler, T.V.5
  • 19
    • 0030023672 scopus 로고    scopus 로고
    • Adhesion and invasion of bovine endothelial cells by Neospora caninum
    • Hemphill A., Gottstein B., and Kaufmann H. Adhesion and invasion of bovine endothelial cells by Neospora caninum. Parasitology 112 (1996) 183-197
    • (1996) Parasitology , vol.112 , pp. 183-197
    • Hemphill, A.1    Gottstein, B.2    Kaufmann, H.3
  • 20
    • 0033042875 scopus 로고    scopus 로고
    • The host-parasite relationship in neosporosis
    • Hemphill A. The host-parasite relationship in neosporosis. Adv. Parasitol. 43 (1999) 47-104
    • (1999) Adv. Parasitol. , vol.43 , pp. 47-104
    • Hemphill, A.1
  • 21
    • 33747074886 scopus 로고    scopus 로고
    • Cellular and immunological basis of the host-parasite relationship during infection with Neospora caninum
    • Hemphill A., Vonlaufen N., and Naguleswaran A. Cellular and immunological basis of the host-parasite relationship during infection with Neospora caninum. Parasitology 133 (2006) 261-278
    • (2006) Parasitology , vol.133 , pp. 261-278
    • Hemphill, A.1    Vonlaufen, N.2    Naguleswaran, A.3
  • 22
  • 23
    • 35548978109 scopus 로고    scopus 로고
    • The host-parasite relationship in pregnant cattle infected with Neospora caninum
    • Innes E.A. The host-parasite relationship in pregnant cattle infected with Neospora caninum. Parasitology 134 (2007) 1903-1910
    • (2007) Parasitology , vol.134 , pp. 1903-1910
    • Innes, E.A.1
  • 24
    • 33846811391 scopus 로고    scopus 로고
    • Vaccination as a control strategy against the coccidial parasites Eimeria, Toxoplasma and Neospora
    • Innes E.A., and Vermeulen A.N. Vaccination as a control strategy against the coccidial parasites Eimeria, Toxoplasma and Neospora. Parasitology 133 (2006) S145-S168
    • (2006) Parasitology , vol.133
    • Innes, E.A.1    Vermeulen, A.N.2
  • 25
    • 1342281291 scopus 로고    scopus 로고
    • Inclusion of CpG adjuvant with plasmid Dann coding for NcGRA7 improves protection against congenital neosporosis
    • Jenkins M., Parker C., Tuo W., Vinyard B., and Dubey J.P. Inclusion of CpG adjuvant with plasmid Dann coding for NcGRA7 improves protection against congenital neosporosis. Infect. Immun. 72 (2004) 1817-1819
    • (2004) Infect. Immun. , vol.72 , pp. 1817-1819
    • Jenkins, M.1    Parker, C.2    Tuo, W.3    Vinyard, B.4    Dubey, J.P.5
  • 26
    • 5644247757 scopus 로고    scopus 로고
    • Evaluation of vaccination with Neospora caninum protein for prevention of fetal loss associated with experimentally induced neosporosis in sheep
    • Jenkins M.C., Tuo W., and Dubey J.P. Evaluation of vaccination with Neospora caninum protein for prevention of fetal loss associated with experimentally induced neosporosis in sheep. Am. J. Vet. Res. 65 (2004) 1404-1408
    • (2004) Am. J. Vet. Res. , vol.65 , pp. 1404-1408
    • Jenkins, M.C.1    Tuo, W.2    Dubey, J.P.3
  • 28
    • 33846881091 scopus 로고    scopus 로고
    • Natural killer cells act as early responders in an experimental infection with Neospora caninum in calves
    • Klevar S., Kulberg S., Boysen P., Storset A.K., Moldal T., Bjorkman C., and Olsen I. Natural killer cells act as early responders in an experimental infection with Neospora caninum in calves. Int. J. Parasitol. 37 (2007) 329-339
    • (2007) Int. J. Parasitol. , vol.37 , pp. 329-339
    • Klevar, S.1    Kulberg, S.2    Boysen, P.3    Storset, A.K.4    Moldal, T.5    Bjorkman, C.6    Olsen, I.7
  • 29
    • 0034910058 scopus 로고    scopus 로고
    • Genetic immunization with plasmid DNA coding for the ROP2 protein of Toxoplasma gondii
    • Leyva R., Hérion P., and Saavedra R. Genetic immunization with plasmid DNA coding for the ROP2 protein of Toxoplasma gondii. Parasitol. Res. 87 (2001) 70-79
    • (2001) Parasitol. Res. , vol.87 , pp. 70-79
    • Leyva, R.1    Hérion, P.2    Saavedra, R.3
  • 31
    • 0033404134 scopus 로고    scopus 로고
    • Prevention of vertical transfer of Neospora caninum in BALB/c mice by vaccination
    • Liddell S., Jenkins M., Collica C.M., and Dubey J.P. Prevention of vertical transfer of Neospora caninum in BALB/c mice by vaccination. J. Parasitol. 85 (1999) 1072-1075
    • (1999) J. Parasitol. , vol.85 , pp. 1072-1075
    • Liddell, S.1    Jenkins, M.2    Collica, C.M.3    Dubey, J.P.4
  • 32
    • 0038006413 scopus 로고    scopus 로고
    • Immunization of mice with plasmid DNA coding for NcGRA7 and NcHSP33 confers partial protection against vertical transmission of Neospora caninum
    • Liddell S., Parker C., Vinyard B., Jenkins M., and Dubey J.P. Immunization of mice with plasmid DNA coding for NcGRA7 and NcHSP33 confers partial protection against vertical transmission of Neospora caninum. J. Parasitol. 89 (2003) 496-500
    • (2003) J. Parasitol. , vol.89 , pp. 496-500
    • Liddell, S.1    Parker, C.2    Vinyard, B.3    Jenkins, M.4    Dubey, J.P.5
  • 33
    • 0031957265 scopus 로고    scopus 로고
    • Comparison of intracerebral parasite load, lesion development, and systemic cytokines in mouse strains infected with Neospora caninum
    • Long M.T., Baszler T.V., and Mathison B.A. Comparison of intracerebral parasite load, lesion development, and systemic cytokines in mouse strains infected with Neospora caninum. J. Parasitol. 84 (1998) 316-320
    • (1998) J. Parasitol. , vol.84 , pp. 316-320
    • Long, M.T.1    Baszler, T.V.2    Mathison, B.A.3
  • 34
    • 33846561691 scopus 로고    scopus 로고
    • The Toxoplasma gondii parasitophorous vacuole membrane: transactions across the border
    • Martin A.M., Liu T., Lynn B.C., and Sinai A.P. The Toxoplasma gondii parasitophorous vacuole membrane: transactions across the border. J. Eukaryot. Microbiol. 54 (2007) 25-28
    • (2007) J. Eukaryot. Microbiol. , vol.54 , pp. 25-28
    • Martin, A.M.1    Liu, T.2    Lynn, B.C.3    Sinai, A.P.4
  • 36
    • 0036136354 scopus 로고    scopus 로고
    • Application of real time fluorescent PCR for quantitative assessment of Neospora caninum infections in organotypic slice cultures of rat central nervous tissue
    • Müller N., Vonlaufen N., Gianinazzi C., Leib S.L., and Hemphill A. Application of real time fluorescent PCR for quantitative assessment of Neospora caninum infections in organotypic slice cultures of rat central nervous tissue. J. Clin. Microbiolol. 40 (2002) 252-255
    • (2002) J. Clin. Microbiolol. , vol.40 , pp. 252-255
    • Müller, N.1    Vonlaufen, N.2    Gianinazzi, C.3    Leib, S.L.4    Hemphill, A.5
  • 37
    • 34547828244 scopus 로고    scopus 로고
    • Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole
    • Müller J., Sterk M., Hemphill A., and Müller N. Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole. J. Antimicrob. Chemother. 60 (2007) 280-287
    • (2007) J. Antimicrob. Chemother. , vol.60 , pp. 280-287
    • Müller, J.1    Sterk, M.2    Hemphill, A.3    Müller, N.4
  • 38
    • 0141862138 scopus 로고    scopus 로고
    • Neospora caninum and Toxoplasma gondii: a novel adhesion/invasion assay reveals distinct differences in tachyzoite-host cell interactions
    • Naguleswaran A., Müller N., and Hemphill A. Neospora caninum and Toxoplasma gondii: a novel adhesion/invasion assay reveals distinct differences in tachyzoite-host cell interactions. Exp. Parasitol. 104 (2003) 149-158
    • (2003) Exp. Parasitol. , vol.104 , pp. 149-158
    • Naguleswaran, A.1    Müller, N.2    Hemphill, A.3
  • 39
    • 0035825606 scopus 로고    scopus 로고
    • Prevention of vertical transmission of Neospora caninum in BALB/c mice by recombinant vaccinia virus carrying NcSRS2 gene
    • Nishikawa Y., Xuan X., Nagasawa H., Igarashi I., Fujisaki K., Otsuka H., and Mikami T. Prevention of vertical transmission of Neospora caninum in BALB/c mice by recombinant vaccinia virus carrying NcSRS2 gene. Vaccine 19 (2001) 1710-1716
    • (2001) Vaccine , vol.19 , pp. 1710-1716
    • Nishikawa, Y.1    Xuan, X.2    Nagasawa, H.3    Igarashi, I.4    Fujisaki, K.5    Otsuka, H.6    Mikami, T.7
  • 40
    • 34548678210 scopus 로고    scopus 로고
    • Prevention of vertical transmission of Neospora caninum in C57BL/6 mice vaccinated with Brucella abortus strain RB51 expressing N. caninum protective antigens
    • Ramamoorthy S., Sanakkayala N., Vemulapalli R., Jain N., Lindsay D.S., Schurig G.S., Boyle S.M., and Sriranganathan N. Prevention of vertical transmission of Neospora caninum in C57BL/6 mice vaccinated with Brucella abortus strain RB51 expressing N. caninum protective antigens. Int. J. Parasitol. 37 (2007) 1531-1538
    • (2007) Int. J. Parasitol. , vol.37 , pp. 1531-1538
    • Ramamoorthy, S.1    Sanakkayala, N.2    Vemulapalli, R.3    Jain, N.4    Lindsay, D.S.5    Schurig, G.S.6    Boyle, S.M.7    Sriranganathan, N.8
  • 41
    • 0023942647 scopus 로고
    • Nitrocellulose-bound antigen repeatedly used for the affinity purification of specific polyclonal antibodies for screening DNA expression libraries
    • Robinson P.A., Anderton B.H., and Loviny T.L. Nitrocellulose-bound antigen repeatedly used for the affinity purification of specific polyclonal antibodies for screening DNA expression libraries. J. Immunol. Methods 108 (1988) 115-122
    • (1988) J. Immunol. Methods , vol.108 , pp. 115-122
    • Robinson, P.A.1    Anderton, B.H.2    Loviny, T.L.3
  • 42
    • 0029736421 scopus 로고    scopus 로고
    • Epitopes recognized by human T lymphocytes in the ROP2 protein antigen of Toxoplasma gondii
    • Saavedra R., Becerril M.A., Dubeaux C., Lippens R., De Vos M.J., and Hérion P. Epitopes recognized by human T lymphocytes in the ROP2 protein antigen of Toxoplasma gondii. Infect. Immun. 64 (1996) 3858-3862
    • (1996) Infect. Immun. , vol.64 , pp. 3858-3862
    • Saavedra, R.1    Becerril, M.A.2    Dubeaux, C.3    Lippens, R.4    De Vos, M.J.5    Hérion, P.6
  • 43
    • 33846322896 scopus 로고    scopus 로고
    • Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue
    • Saeij J.P.J., Coller S., Boyle J.P., Jerome M.E., White M.W., and Boothroyd J.C. Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue. Nature 445 (2007) 324-327
    • (2007) Nature , vol.445 , pp. 324-327
    • Saeij, J.P.J.1    Coller, S.2    Boyle, J.P.3    Jerome, M.E.4    White, M.W.5    Boothroyd, J.C.6
  • 44
    • 51249112858 scopus 로고    scopus 로고
    • Vaccination with microneme protein NcMIC4 increases mortality in mice inoculated with Neospora caninum
    • Srinivasan S., Müller J., Suana A., and Hemphill A. Vaccination with microneme protein NcMIC4 increases mortality in mice inoculated with Neospora caninum. Parasitology 92 (2007) 1235-1243
    • (2007) Parasitology , vol.92 , pp. 1235-1243
    • Srinivasan, S.1    Müller, J.2    Suana, A.3    Hemphill, A.4
  • 45
    • 37449019188 scopus 로고    scopus 로고
    • Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formomonetin
    • Sterk M., Müller J., Hemphill A., and Müller N. Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formomonetin. Microbiology 153 (2007) 4150-4158
    • (2007) Microbiology , vol.153 , pp. 4150-4158
    • Sterk, M.1    Müller, J.2    Hemphill, A.3    Müller, N.4
  • 47
    • 0034442049 scopus 로고    scopus 로고
    • Endometriosis and recurrent pregnancy loss
    • Vercammen E.E., and D'Hooghe T.M. Endometriosis and recurrent pregnancy loss. Semin. Reprod. Med. 18 (2000) 363-368
    • (2000) Semin. Reprod. Med. , vol.18 , pp. 363-368
    • Vercammen, E.E.1    D'Hooghe, T.M.2
  • 48
    • 0021355340 scopus 로고
    • A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids
    • Wessel D., and Flügge U.I. A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. Anal. Biochem. 138 (1984) 141-143
    • (1984) Anal. Biochem. , vol.138 , pp. 141-143
    • Wessel, D.1    Flügge, U.I.2
  • 49
    • 33645093214 scopus 로고    scopus 로고
    • Protecting babies: vaccine strategies to prevent foetal infection in Neospora caninum infected cattle
    • Williams D.J.L., and Trees A.J. Protecting babies: vaccine strategies to prevent foetal infection in Neospora caninum infected cattle. Parasite Immunol. 28 (2006) 61-67
    • (2006) Parasite Immunol. , vol.28 , pp. 61-67
    • Williams, D.J.L.1    Trees, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.