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Volumn 10, Issue 12, 2014, Pages 3711-3721

Gene expression profiles identify both MyD88-independent and MyD88-dependent pathways involved in the maturation of dendritic cells mediated by heparan sulfate: A novel adjuvant

Author keywords

Dendritic cells; Gene expression profile; Heparan sulfate; Humoral immune response; Toll like receptor signaling pathway; Vaccine adjuvant

Indexed keywords

ALUMINUM POTASSIUM SULFATE; B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; FREUND ADJUVANT; HEPARAN SULFATE; HEPATITIS A VACCINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G ANTIBODY; INTERFERON REGULATORY FACTOR 7; MYELOID DIFFERENTIATION FACTOR 88; RABIES VACCINE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; IMMUNOLOGICAL ADJUVANT; MYD88 PROTEIN, MOUSE; TRANSCRIPTOME;

EID: 84922550971     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.4161/21645515.2014.980682     Document Type: Article
Times cited : (12)

References (64)
  • 3
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • PMID:2700931
    • Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 1989; 54(Pt 1):1-13; PMID:2700931; http://dx.doi.org/10.1101/SQB.1989. 054.01.003
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , pp. 1-13
    • Janeway, C.A.1
  • 4
    • 0030687891 scopus 로고    scopus 로고
    • Cytokines and the mechanisms of action of vaccine adjuvants
    • PMID:9740352
    • Brewer JM, Alexander J. Cytokines and the mechanisms of action of vaccine adjuvants. Cytokines Cell Mol Ther 1997; 3:233-46; PMID:9740352
    • (1997) Cytokines Cell Mol Ther , vol.3 , pp. 233-246
    • Brewer, J.M.1    Alexander, J.2
  • 5
    • 0012929728 scopus 로고    scopus 로고
    • Toll-like receptors
    • PMID:12524386
    • Takeda K, Kaisho T, Akira S. Toll-like receptors. Annu Rev Immunol 2003; 21:335-76; PMID:12524386; http://dx.doi.org/10.1146/annurev.immunol.21.120601. 141126
    • (2003) Annu Rev Immunol , vol.21 , pp. 335-376
    • Takeda, K.1    Kaisho, T.2    Akira, S.3
  • 6
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • PMID:15454922
    • Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5 (October (10)):987-95; PMID:15454922; http://dx. doi.org/10.1038/ni1112
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 7
    • 30544448127 scopus 로고    scopus 로고
    • Triggering TLR signaling in vaccination
    • PMID:16310411
    • van Duin D, Medzhitov R, Shaw AC. Triggering TLR signaling in vaccination. Trends Immunol 2006; 27 (January (1)):49-55; PMID:16310411; http://dx.doi. org/10.1016/j.it.2005.11.005
    • (2006) Trends Immunol , vol.27 , pp. 49-55
    • Van Duin, D.1    Medzhitov, R.2    Shaw, A.C.3
  • 8
    • 0036954037 scopus 로고    scopus 로고
    • Recognition of lipopeptides by toll-like receptors
    • PMID:12697090
    • Takeda K, Takeuchi O, Akira S. Recognition of lipopeptides by toll-like receptors. J Endotoxin Res 2002; 8 (6):459-63; PMID:12697090; http://dx.doi.org/ 10.1179/096805102125001073
    • (2002) J Endotoxin Res , vol.8 , Issue.6 , pp. 459-463
    • Takeda, K.1    Takeuchi, O.2    Akira, S.3
  • 10
    • 33845224163 scopus 로고    scopus 로고
    • Vaccination with recombinant fusion proteins incorporating Tolllike receptor ligands induces rapid cellular and humoral immunity
    • PMID:16968658
    • Huleatt JW, Jacobs AR, Tang J, Desai P, Kopp EB, Huang Y, Song L, Nakaar V, Powell TJ. Vaccination with recombinant fusion proteins incorporating Tolllike receptor ligands induces rapid cellular and humoral immunity. Vaccine 2007; 25(January 8 (4)):763-75; PMID:16968658; http://dx.doi.org/10.1016/j.vaccine. 2006.08.013
    • (2007) Vaccine , vol.25 , pp. 763-775
    • Huleatt, J.W.1    Jacobs, A.R.2    Tang, J.3    Desai, P.4    Kopp, E.B.5    Huang, Y.6    Song, L.7    Nakaar, V.8    Powell, T.J.9
  • 11
    • 40649097299 scopus 로고    scopus 로고
    • The microbialmimic poly IC induces durable and protective CD4C T cell immunity together with a dendritic cell targeted vaccine
    • PMID:18256187
    • Trumpfheller C, Caskey M, Nchinda G, Longhi MP, Mizenina O, Huang Y, Schlesinger SJ, Colonna M, Steinman RM. The microbialmimic poly IC induces durable and protective CD4C T cell immunity together with a dendritic cell targeted vaccine. Proc Natl Acad Sci USA 2008; 105(February 19 (7)):2574-9; PMID:18256187; http://dx.doi.org/10.1073/ pnas.0711976105
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2574-2579
    • Trumpfheller, C.1    Caskey, M.2    Nchinda, G.3    Longhi, M.P.4    Mizenina, O.5    Huang, Y.6    Schlesinger, S.J.7    Colonna, M.8    Steinman, R.M.9
  • 12
    • 27244443079 scopus 로고    scopus 로고
    • HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8C T cell responses in nonhuman primates
    • PMID:16219698
    • Wille-Reece U, Flynn BJ, Lore K, Koup RA, Kedl RM, Mattapallil JJ, Weiss WR, Roederer M, Seder RA. HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8C T cell responses in nonhuman primates. Proc Natl Acad Sci USA 2005; 102(October 18 (42)):15190-4; PMID:16219698; http://dx.doi.org/ 10.1073/pnas.0507484102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15190-15194
    • Wille-Reece, U.1    Flynn, B.J.2    Lore, K.3    Koup, R.A.4    Kedl, R.M.5    Mattapallil, J.J.6    Weiss, W.R.7    Roederer, M.8    Seder, R.A.9
  • 13
    • 33644746129 scopus 로고    scopus 로고
    • A CpG oligonucleotide can protect mice from a low aerosol challenge dose of Burkholderia mallei
    • PMID:16495571
    • Waag DM, McCluskie MJ, Zhang N, Krieg AM. A CpG oligonucleotide can protect mice from a low aerosol challenge dose of Burkholderia mallei. Infect Immun 2006; 74(March (3)):1944-8; PMID:16495571; http://dx.doi.org/10.1128/IAI.74.3. 1944-1948.2006
    • (2006) Infect Immun , vol.74
    • Waag, D.M.1    McCluskie, M.J.2    Zhang, N.3    Krieg, A.M.4
  • 14
    • 0037018097 scopus 로고    scopus 로고
    • Adjuvants of immunity: Harnessing innate immunity to promote adaptive immunity
    • PMID:11877490
    • Bendelac A, Medzhitov R. Adjuvants of immunity: harnessing innate immunity to promote adaptive immunity. J Exp Med 2002; 195:F19-23; PMID:11877490; http://dx.doi.org/10.1084/jem.20020073
    • (2002) J Exp Med , vol.195 , pp. F19-23
    • Bendelac, A.1    Medzhitov, R.2
  • 15
    • 0031045622 scopus 로고    scopus 로고
    • Origin, maturation and antigen presenting function of dendritic cells
    • PMID:9039784
    • Cella M, Sallusto F, Lanzavecchia A. Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 1997; 9:10-16; PMID:9039784; http://dx.doi.org/10.1016/S0952-7915(97)80153-7
    • (1997) Curr Opin Immunol , vol.9 , pp. 10-16
    • Cella, M.1    Sallusto, F.2    Lanzavecchia, A.3
  • 16
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • PMID:8893001
    • Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996; 383:787-93; PMID:8893001; http://dx.doi.org/10.1038/383787a0
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 17
    • 0038189732 scopus 로고    scopus 로고
    • Propagation and control of T-cell responses by heparan sulfate-bound IL-2
    • PMID:12759423
    • Wrenshall LE, Platt JL, Stevens ET, Wight TN, Miller JD. Propagation and control of T-cell responses by heparan sulfate-bound IL-2. J. Immunol 2003; 170 (11): 5470-4; PMID:12759423; http://dx.doi.org/ 10.4049/jimmunol.170.11.5470
    • (2003) J. Immunol , vol.170 , Issue.11 , pp. 5470-5474
    • Wrenshall, L.E.1    Platt, J.L.2    Stevens, E.T.3    Wight, T.N.4    Miller, J.D.5
  • 18
    • 84867316465 scopus 로고    scopus 로고
    • Heparan sulfate an endogenous TLR4 agonist promotes acute GVHD after allogeneic stem cell transplantation
    • PMID:22760779
    • Brennan TV, Lin L, Huang X, Cardona D M, Li Z, Dredge K, Yang Y. Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation. Blood 2012; 120(14); 2899-908; PMID:22760779; http://dx.doi.org/10.1182/ blood-2011-07-368720
    • (2012) Blood , vol.120 , Issue.14 , pp. 2899-2908
    • Brennan, T.V.1    Lin, L.2    Huang, X.3    Cardona, D.M.4    Li, Z.5    Dredge, K.6    Yang, Y.7
  • 19
    • 0027377719 scopus 로고
    • Role of heparan sulfate in immune system-blood vessel interactions
    • PMID:8274190
    • Ihrcke NS, Wrenshall LE, Lindman BJ, Platt JL. Role of heparan sulfate in immune system-blood vessel interactions. Immunol 1993; Today 14:500; PMID:8274190
    • (1993) Immunol , pp. 500
    • Ihrcke, N.S.1    Wrenshall, L.E.2    Lindman, B.J.3    Platt, J.L.4
  • 20
    • 0030060311 scopus 로고    scopus 로고
    • Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix
    • PMID:8652044
    • Gilat D, Cahalon L, Hershkoviz R, Lider O. Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix. Immunol 1996; Today 17:16; PMID:8652044
    • (1996) Immunol , pp. 16
    • Gilat, D.1    Cahalon, L.2    Hershkoviz, R.3    Lider, O.4
  • 21
    • 0031749471 scopus 로고    scopus 로고
    • Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2
    • PMID:9623978
    • Kato M, Wang H, Kainulainen V, Fitzgerald ML, Ledbetter S, Ornitz DM, Bernfield M. Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2. Nat Med 1998; 4:691; PMID:9623978
    • (1998) Nat Med , vol.4 , pp. 691
    • Kato, M.1    Wang, H.2    Kainulainen, V.3    Fitzgerald, M.L.4    Ledbetter, S.5    Ornitz, D.M.6    Bernfield, M.7
  • 22
    • 0030967612 scopus 로고    scopus 로고
    • Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation
    • PMID:9169435
    • Subramanian SV, Fitzgerald ML, Bernfield M. Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation. J Biol Chem 1997; 272:14713; PMID:9169435
    • (1997) J Biol Chem , vol.272 , pp. 14713
    • Subramanian, S.V.1    Fitzgerald, M.L.2    Bernfield, M.3
  • 23
    • 0025993863 scopus 로고
    • The role of C5a and Ab in the release of heparan sulfate from endothelial cells
    • PMID:1936126
    • Platt JL, Dalmasso AP, Lindman BJ, Ihrcke NS, Bach FH. The role of C5a and Ab in the release of heparan sulfate from endothelial cells. Eur J Immunol 1991; 21:2887; PMID:1936126; http://dx.doi.org/10.1002/ eji.1830211135
    • (1991) Eur J Immunol , vol.21 , pp. 2887
    • Platt, J.L.1    Dalmasso, A.P.2    Lindman, B.J.3    Ihrcke, N.S.4    Bach, F.H.5
  • 24
    • 0031966911 scopus 로고    scopus 로고
    • Regulation of platelet heparanase during inflammation: Role of pH and proteinases
    • PMID:9572470
    • Ihrcke NS, Parker W, Reissner KJ, Platt JL. Regulation of platelet heparanase during inflammation: role of pH and proteinases. J Cell Physiol 1998; 175:255; PMID:9572470; http://dx.doi.org/10.1002/(SICI) 1097-4652(199806)175:3%3c255::AID-JCP3%3e3.0. CO;2-N
    • (1998) J Cell Physiol , vol.175 , pp. 255
    • Ihrcke, N.S.1    Parker, W.2    Reissner, K.J.3    Platt, J.L.4
  • 25
    • 0037387945 scopus 로고    scopus 로고
    • Syndecans in inflammation
    • PMID:12665470
    • Gotte M. Syndecans in inflammation. FASEB J 2003; 17, 575-91; PMID:12665470; http://dx.doi.org/ 10.1096/fj.02-0739rev
    • (2003) FASEB J , vol.17 , pp. 575-591
    • Gotte, M.1
  • 26
    • 0036024089 scopus 로고    scopus 로고
    • Chemokines in rapid leukocyte adhesion triggering and migration
    • PMID:11978080
    • Johnston B, Butcher EC. Chemokines in rapid leukocyte adhesion triggering and migration. Semin Immunol 2002; 14:83-92; PMID:11978080; http://dx.doi. org/10.1006/smim.2001.0345
    • (2002) Semin Immunol , vol.14 , pp. 83-92
    • Johnston, B.1    Butcher, E.C.2
  • 27
    • 0028816517 scopus 로고
    • Heparan sulfate initiates signals in murine macrophages leading to divergent biological outcomes
    • PMID:7814890
    • Wrenshall LE, Cerra FB, Singh RK, Platt JL. Heparan sulfate initiates signals in murine macrophages leading to divergent biological outcomes. J Immunol 1995; 154:871; PMID:7814890
    • (1995) J Immunol , vol.154 , pp. 871
    • Wrenshall, L.E.1    Cerra, F.B.2    Singh, R.K.3    Platt, J.L.4
  • 28
    • 0025911987 scopus 로고
    • Regulation of murine splenocyte responses by heparan sulfate
    • PMID:1830063
    • Wrenshall LE, Cerra FB, Carlson A, Bach FH, Platt JL. Regulation of murine splenocyte responses by heparan sulfate. J Immunol 1991; 147:455; PMID:1830063
    • (1991) J Immunol , vol.147 , pp. 455
    • Wrenshall, L.E.1    Cerra, F.B.2    Carlson, A.3    Bach, F.H.4    Platt, J.L.5
  • 29
    • 0032869736 scopus 로고    scopus 로고
    • Modulation of macrophage and B cell function by glycosaminoglycans
    • PMID:10496308
    • Wrenshall LE, Stevens RB, Cerra FB, Platt JL.Modulation of macrophage and B cell function by glycosaminoglycans. J Leukocyte Biol 1999; 66:391; PMID:10496308
    • (1999) J Leukocyte Biol , vol.66 , pp. 391
    • Wrenshall, L.E.1    Stevens, R.B.2    Cerra, F.B.3    Platt, J.L.4
  • 30
    • 0034254204 scopus 로고    scopus 로고
    • Phenotypic and functional maturation of dendritic cells mediated by heparan sulfate
    • PMID:10903769
    • Kodaira Y, Nair SK, Wrenshall LE, Gilboa E, Platt JL. Phenotypic and functional maturation of dendritic cells mediated by heparan sulfate. J Immunol 2000; 165(3): 1599-604; PMID:10903769; http://dx.doi.org/ 10.4049/jimmunol.165.3.1599
    • (2000) J Immunol , vol.165 , Issue.3 , pp. 1599-1604
    • Kodaira, Y.1    Nair, S.K.2    Wrenshall, L.E.3    Gilboa, E.4    Platt, J.L.5
  • 31
    • 79952660834 scopus 로고    scopus 로고
    • Effect of low molecular weight heparan sulfate, an endogenous danger signal, as an immunological adjuvant
    • Lan Y, Wang H-X, Wu MN, Hu N-Z, Hu Y-Z. Effect of low molecular weight heparan sulfate, an endogenous danger signal, as an immunological adjuvant. Chin J Biologicals 2011; January 24(1):5-9
    • (2011) Chin J Biologicals , Issue.1 , pp. 5-9
    • Lan, Y.1    Wang, H.-X.2    Wu, M.N.3    Hu, N.-Z.4    Hu, Y.-Z.5
  • 33
    • 0031867535 scopus 로고    scopus 로고
    • And immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • PMID:9645386
    • Sparwasser T, Koch ES, Vabulas RM, Heeg K, Lipford GB, Ellwart JW, Wagner H. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur J Immunol 1998; 28:2045; PMID:9645386; http://dx. doi.org/10.1002/(SICI)1521-4141(199806)28:06%3c 2045::AID-IMMU2045%3e3.0.CO;2-8
    • (1998) Eur J Immunol , vol.28 , pp. 2045
    • Sparwasser, T.1    Koch, E.S.2    Vabulas, R.M.3    Heeg, K.4    Lipford, G.B.5    Ellwart, J.W.6    Wagner, H.7    Bacterial, D.N.A.8
  • 35
    • 51149090409 scopus 로고    scopus 로고
    • Alum adjuvanticity: Unraveling a century old mystery
    • PMID:18651701
    • De Gregorio E, Tritto E, Rappuoli R. Alum adjuvanticity: unraveling a century old mystery. Eur J Immunol 2008; 38(8):2068-71; PMID:18651701; http://dx.doi. org/10.1002/eji.200838648
    • (2008) Eur J Immunol , vol.38 , Issue.8 , pp. 2068-2071
    • De Gregorio, E.1    Tritto, E.2    Rappuoli, R.3
  • 36
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • PMID:20075244
    • Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010; 327 (5963):291-5; PMID:20075244; http://dx.doi.org/ 10.1126/science.1183021
    • (2010) Science , vol.327 , Issue.5963 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 37
    • 53849109907 scopus 로고    scopus 로고
    • Putting endotoxin to work for us:monophosphoryl lipid A as a safe and effective vaccine adjuvant
    • PMID:18668203
    • Casella CR, Mitchell TC. Putting endotoxin to work for us:monophosphoryl lipid A as a safe and effective vaccine adjuvant. Cell Mol Life Sci 2008; 65:3231-40; PMID:18668203; http://dx.doi.org/10.1007/s00018-008-8228-6
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3231-3240
    • Casella, C.R.1    Mitchell, T.C.2
  • 38
    • 77952540334 scopus 로고    scopus 로고
    • Monophosphoryl lipidA(MPL) as an adjuvant for anti-cancer vaccines: Clinical results
    • PMID:20665204
    • Cluff CW. Monophosphoryl lipidA(MPL) as an adjuvant for anti-cancer vaccines: clinical results. Adv Exp Med Biol 2010; 667:111-23; PMID:20665204; http:// dx.doi.org/10.1007/978-1-4419-1603-7-10
    • (2010) Adv Exp Med Biol , vol.667 , pp. 111-123
    • Cluff, C.W.1
  • 39
    • 77955383770 scopus 로고    scopus 로고
    • DAMPening inflammation by modulating TLR signalling
    • Epub 2010 Jul 13; PMID: 20706656 pii: 672395
    • Piccinini AM, Midwood KS. DAMPening inflammation by modulating TLR signalling. Mediat Inflamm 2010; pii: 672395.Epub 2010 Jul 13; PMID: 20706656; http://dx.doi.org/10.1155/2010/672395
    • (2010) Mediat Inflamm
    • Piccinini, A.M.1    Midwood, K.S.2
  • 40
    • 77649334441 scopus 로고    scopus 로고
    • Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation
    • PMID:20102311
    • Kis-Toth K, Tsokos GC. Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation. Autoimmunity 2010; 43(2):121-30; PMID:20102311; http://dx.doi.org/10.3109/ 08916930903214041
    • (2010) Autoimmunity , vol.43 , Issue.2 , pp. 121-130
    • Kis-Toth, K.1    Tsokos, G.C.2
  • 43
    • 0037094084 scopus 로고    scopus 로고
    • Receptormediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4
    • PMID:11994480
    • Johnson GB, Brunn GJ, Kodaira Y, Platt JL. Receptormediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol 2002; 168:5233-9; PMID:11994480; http:// dx.doi.org/10.4049/jimmunol.168.10.5233
    • (2002) J Immunol , vol.168 , pp. 5233-5239
    • Johnson, G.B.1    Brunn, G.J.2    Kodaira, Y.3    Platt, J.L.4
  • 44
    • 20544474210 scopus 로고    scopus 로고
    • Pathogen recognition with Toll-like receptors
    • Kawai T, Akira S. Pathogen recognition with Toll-like receptors. Curr Opin Immunol 2005; 17:338-44
    • (2005) Curr Opin Immunol , vol.17 , pp. 338-344
    • Kawai, T.1    Akira, S.2
  • 45
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • PMID:10435584
    • Kawai T, Adachi O, Ogawa T, Takeda K, Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 1999; 11:115-22; PMID:10435584; http://dx.doi.org/10.1016/S1074-7613(00)80086-2
    • (1999) Immunity , vol.11 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 46
    • 3242807395 scopus 로고    scopus 로고
    • Functions of toll-like receptors: Lessons from KO mice
    • PMID:15330257
    • Akira S, Takeda K. Functions of toll-like receptors: lessons from KO mice. C R Biol 2004; 327:581-9; PMID:15330257
    • (2004) C R Biol , vol.327 , pp. 581-589
    • Akira, S.1    Takeda, K.2
  • 47
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Feb 24, PMID:16497588
    • Akira S1, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; Feb 24;124 (4):783-801; PMID:16497588; http://dx.doi.org/ 10.1016/j.cell.2006.02.015
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 49
    • 0035339861 scopus 로고    scopus 로고
    • Endotoxin-induced maturation of MyD88-deficient dendritic cells
    • PMID:11313410
    • Kaisho T, Takeuchi O, Kawai T, Hoshino K, Akira S. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J Immunol 2001; 166(9):5688-94; PMID:11313410; http://dx.doi.org/10.4049/jimmunol. 166.9.5688
    • (2001) J Immunol , vol.166 , Issue.9 , pp. 5688-5694
    • Kaisho, T.1    Takeuchi, O.2    Kawai, T.3    Hoshino, K.4    Akira, S.5
  • 50
    • 84898967990 scopus 로고    scopus 로고
    • TLR4-mediated pro-inflammatory dendritic cell differentiation in humans requires the combined action of MyD88 and TRIF
    • PMID:23941760
    • Kolanowski ST, Dieker MC, Lissenberg-Thunnissen SN, van Schijndel GM, van Ham SM, Brinke AT. TLR4-mediated pro-inflammatory dendritic cell differentiation in humans requires the combined action of MyD88 and TRIF. Innate Immun 2014; 20(4):423-30; PMID:23941760; http://dx.doi.org/10.1177/ 1753425913498626
    • (2014) Innate Immun , vol.20 , Issue.4 , pp. 423-430
    • Kolanowski, S.T.1    Dieker, M.C.2    Lissenberg-Thunnissen, S.N.3    Van Schijndel, G.M.4    Van Ham, S.M.5    Brinke, A.T.6
  • 51
    • 49649109586 scopus 로고    scopus 로고
    • Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation
    • PMID:18641322
    • Shen H, Tesar BM, Walker WE, Goldstein DR. Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation. J Immunol 2008; 181:1849-58; PMID:18641322; http://dx.doi. org/10.4049/jimmunol.181.3.1849
    • (2008) J Immunol , vol.181 , pp. 1849-1858
    • Shen, H.1    Tesar, B.M.2    Walker, W.E.3    Goldstein, D.R.4
  • 52
    • 0347146027 scopus 로고    scopus 로고
    • Upregulation of costimulatory molecules induced by lipopolysaccharide and doublestranded RNA occurs by Trif-dependent and Trif-independent pathways
    • PMID:14625548
    • Hoebe K, Janssen EM, Kim SO, Alexopoulou L, Flavell RA, Han J, Beutler B. Upregulation of costimulatory molecules induced by lipopolysaccharide and doublestranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol 2003; 4:1223-9; PMID:14625548; http://dx.doi.org/10.1038/ni1010
    • (2003) Nat Immunol , vol.4 , pp. 1223-1229
    • Hoebe, K.1    Janssen, E.M.2    Kim, S.O.3    Alexopoulou, L.4    Flavell, R.A.5    Han, J.6    Beutler, B.7
  • 53
    • 83755173986 scopus 로고    scopus 로고
    • TLR4 dependent heparan sulphate- induced pancreatic inflammatory response is IRF3-mediated
    • PMID:22188870
    • Akbarshahi H, Axelsson JB, Said K, Malmstrom A, Fischer H, Andersson R. TLR4 dependent heparan sulphate- induced pancreatic inflammatory response is IRF3-mediated. J Transl Med 2011; 9:219; PMID:22188870; http://dx.doi.org/10.1186/1479-5876-9-219
    • (2011) J Transl Med , vol.9 , pp. 219
    • Akbarshahi, H.1    Axelsson, J.B.2    Said, K.3    Malmstrom, A.4    Fischer, H.5    Andersson, R.6
  • 54
    • 18644364701 scopus 로고    scopus 로고
    • A type i interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
    • PMID:15851485
    • Gautier G, Humbert M, Deauvieau F, Scuiller M, Hiscott J, Bates EEM, Trinchieri G, Caux C, Garrone P. A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J Exp Med 2005; 201:1435-46; PMID:15851485; http://dx.doi.org/10.1084/jem.2004 1964
    • (2005) J Exp Med , vol.201 , pp. 1435-1446
    • Gautier, G.1    Humbert, M.2    Deauvieau, F.3    Scuiller, M.4    Hiscott, J.5    Bates, E.E.M.6    Trinchieri, G.7    Caux, C.8    Garrone, P.9
  • 55
    • 79952091851 scopus 로고    scopus 로고
    • CXCR3 in T cell function
    • PMID:21376175
    • Groom JR, Luster AD. CXCR3 in T cell function. Exp Cell Res 2011; 317:620-31; PMID:21376175; http:// dx.doi.org/10.1016/j.yexcr.2010.12.017
    • (2011) Exp Cell Res , vol.317 , pp. 620-631
    • Groom, J.R.1    Luster, A.D.2
  • 56
    • 84883543962 scopus 로고    scopus 로고
    • MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant
    • PMID:23716300
    • Orr MT, Duthie MS, Windish HP, Lucas EA, Guderian JA, Hudson TE, Coler RN. MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant. Eur J Immunol 2013; 43 (9):2398-408; PMID:23716300; http://dx.doi.org/ 10.1002/eji.201243124
    • (2013) Eur J Immunol , vol.43 , Issue.9 , pp. 2398-2408
    • Orr, M.T.1    Duthie, M.S.2    Windish, H.P.3    Lucas, E.A.4    Guderian, J.A.5    Hudson, T.E.6    Coler, R.N.7
  • 57
    • 34250854079 scopus 로고    scopus 로고
    • The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
    • PMID:17569868
    • Mata-Haro V, Cekic C, Martin M, Chilton PM, Casella CR, Mitchell TC. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science 2007; 316:1628-32; PMID:17569868; http:// dx.doi.org/10.1126/science.1138963
    • (2007) Science , vol.316 , pp. 1628-1632
    • Mata-Haro, V.1    Cekic, C.2    Martin, M.3    Chilton, P.M.4    Casella, C.R.5    Mitchell, T.C.6
  • 58
    • 70450253086 scopus 로고    scopus 로고
    • Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A
    • PMID:19759006
    • Cekic C, Casella CR, Eaves CA, Matsuzawa A, Ichijo H, Mitchell TC. Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A. J Biol Chem 2009; 284:31982-91; PMID:19759006; http:// dx.doi.org/10.1074/jbc.M109.046383
    • (2009) J Biol Chem , vol.284 , pp. 31982-31991
    • Cekic, C.1    Casella, C.R.2    Eaves, C.A.3    Matsuzawa, A.4    Ichijo, H.5    Mitchell, T.C.6
  • 60
    • 84874033208 scopus 로고    scopus 로고
    • TRIF is required for TLR4 mediated adjuvant effects on T cell clonal expansion
    • PMID:23457630
    • Gandhapudi SK, Chilton PM, Mitchell TC. TRIF is required for TLR4 mediated adjuvant effects on T cell clonal expansion. PLoS One 2013; 8(2):e56855; PMID:23457630; http://dx.doi.org/10.1371/journal. pone.0056855
    • (2013) PLoS One , vol.8 , Issue.2
    • Gandhapudi, S.K.1    Chilton, P.M.2    Mitchell, T.C.3
  • 61
    • 77956828437 scopus 로고    scopus 로고
    • TLR4 ligands augment antigen-specific CD8C T lymphocyte responses elicited by a viral vaccine vector
    • PMID:20631129
    • Rhee EG, Kelley RP, Agarwal I, Lynch DM, La Porte A, Simmons NL, Clark SL, Barouch DH. TLR4 ligands augment antigen-specific CD8C T lymphocyte responses elicited by a viral vaccine vector. J Virol 2010; 84:10413-9; PMID:20631129; http://dx.doi. org/10.1128/JVI.00928-10
    • (2010) J Virol , vol.84 , pp. 10413-10419
    • Rhee, E.G.1    Kelley, R.P.2    Agarwal, I.3    Lynch, D.M.4    La Porte, A.5    Simmons, N.L.6    Clark, S.L.7    Barouch, D.H.8
  • 62
    • 75549089019 scopus 로고    scopus 로고
    • Primer-Bank: A resource of human and mouse PCR primer pairs for gene expression detection and quantification
    • PMID:19906719
    • Athanasia S, Xiaowei W, Huajun W, Brian S. Primer-Bank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification. Nucl Acids Res 2010; 38:D792-9; PMID:19906719; http://dx.doi.org/10.1093/nar/gkp1005
    • (2010) Nucl Acids Res , vol.38 , pp. D792-D799
    • Athanasia, S.1    Xiaowei, W.2    Huajun, W.3    Brian, S.4
  • 63
    • 58949097577 scopus 로고    scopus 로고
    • A comprehensive collection of experimentally validated primers for Polymerase chain reaction quantitation of murine transcript abundance
    • PMID:19108745
    • Athanasia S, Xiaowei W, Huajun W, Stefan D, Tara T, Brian S. A comprehensive collection of experimentally validated primers for Polymerase chain reaction quantitation of murine transcript abundance. BMC Genomics 2008; 9:633; PMID:19108745; http://dx.doi.org/ 10.1186/1471-2164-9-633
    • (2008) BMC Genomics , vol.9 , pp. 633
    • Athanasia, S.1    Xiaowei, W.2    Huajun, W.3    Stefan, D.4    Tara, T.5    Brian, S.6
  • 64
    • 85074914953 scopus 로고    scopus 로고
    • A PCR primer bank for quantitative gene expression analysis
    • PMID:14654707
    • Xiaowei W, Brian S. A PCR primer bank for quantitative gene expression analysis. Nucleic Acids Res 2003; 31(24):e154; 1-8; PMID:14654707; http://dx.doi.org/ 10.1093/nar/gng154
    • (2003) Nucleic Acids Res , vol.31 , Issue.24 , pp. 1-8
    • Xiaowei, W.1    Brian, S.2


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